Gene 83791.m00055 (T.vaginalis)

83791.m00055

Species: T.vaginalis
Alias: TvagK0279, 83791.m00055
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
83791.m00055.AA Protein None 1000 None Fasta, JSON
83791.m00055.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of 83791.m00055.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83791.m00055.AA TKL 200-443 22 3.1e-79 269.53 In-house 1-364 (364) Show / Hide 
Range on Protein: 200-443
Range on HMM: 1-364/364
Sequence Identity: 22% (84 aa)

IGAGAYAKVFKAIFNATN--------ETIAIKELTRIDMPPRKL-------------------------FTLKREINCLMNLNHPNCIKFYGVTVIPP--
|| |....|.|.... ..        ...|.| . . ..  . .                         |....||... .|.||| ..|.|.   ||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FSIITKFIPHGSLYDLLVNNPDDLTPLRRMKIAIGITRGLEYLDLVH--------VLHRDIKPQNILIDENDH--------------A
            . |.. ..|.|||...|        . .|...|..| ||..||   .        ..|||.|..|||.||| .              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

VLCDFGLSRSF----GPKMTA------------------ELGTIAYMAPELMGNS--FT------------SYDSSCDTYSFGILLYDLLMG--PAKYMQ
 .|||||||..    . ..|.                  . ||...||||.. ..  .|            .|. .|| |||||.|. .| .  | . . 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

MFPVQIA-------MRVLKEKYRPELP-----------NDNH--SFCELITQCWSQNPRKRPKMSVIRKKL
..|....       | | ....||..|           ...   |...|...||...|.||| .. | |.|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 83791.m00055.AA TKL-Unique 198-443 30 1.6e-60 207.34 In-house 3-290 (290) Show / Hide 
Range on Protein: 198-443
Range on HMM: 3-290/290
Sequence Identity: 30% (89 aa)

EQIGAGAYAKVFKAIFNATNETIAIKELT-RIDMPPRKLFTLKREINCLMNLN-HPNCIKFYGVTV----IPP-FSIITKFIPHGSLYDLLV--------
. ||.|.|..|.|.... .   .||| .    |  .........|.| . .|. |||  ...|...     || ..|.. ..|.|||||.|         
NKIGEGGYGQVYKGKWRGYP--VAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-NNPDDLTPLRRMKIAIGITRGLEYLDLVH--VLHRDIKPQNILIDEN-----DHAVLCDFGLSRSFG--PKMTAE----------LGTIAYMAPELMGN
 ||  .|....|.|.|| | .|..||      ..|||.|..|.|.|.|       . .||||||..     |||.           .|.. .||||.. .
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

SFTSYDSSCDTYSFGILLYDLLMGPA------KYMQMFPVQIAMRVLK--EKYRPELPND-NHSFCELITQCWSQNPRKRPKMSVIRKKL
.|. |. ..| ||||| |. .. .         |  | . |..  | .  |.|||..||. . .. .||.||| ..| .||  . |...|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 83791.m00055.AA MLK 194-443 29 8.2e-59 201.71 In-house 1-291 (291) Show / Hide 
Range on Protein: 194-443
Range on HMM: 1-291/291
Sequence Identity: 29% (87 aa)

FTKQEQIGAGAYAKVFKAIFNATN---ETIAIKELT-RIDMPPRK----LFTLKREINCLMNLNHPN----CIKFYGVTVIP-P-FSIITKFIPHGSLYD
.. .| ||.|.. ||.|. . ...    ..|.|. . ||.    .       ...|.. |  |.|||     |.||||   | . | |.. ....||||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

LL---VNNPDD----------LTPLRRMKIAIGITRGLEYL---DLVHVLHRDIKPQNILIDE------NDHAVLCDFGLSRSFGPK---MTAELGTIAY
.|    ....|           ..   |..|  . ||..||   . . . |||.|..||||||      ..... ||||.||..  .   |.   || |.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPELMGN-SFTSYDSSCDTYSFGILLYDLLMGPAKYM-QMFPVQIAMRVLKEKYRPELPND-NHSFCELITQCWSQNPRKRPKMSVIRKKL
||||       . |. .|| .|.|..|. .| .   |   . | .||. |  .. || .|.. ......|..|||.|.|.|||... | ..|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 83791.m00055.AA LRRK 194-445 23 9.1e-59 201.56 In-house 1-351 (351) Show / Hide 
Range on Protein: 194-445
Range on HMM: 1-351/351
Sequence Identity: 23% (83 aa)

FTKQEQIGAGAYA-KVFKAIFN--------------------------ATNETIAIKELTR--------------------------------IDMPPRK
. ..|||| |... .|..|...                          .  ...||| ..|                                ... .|.
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LFTLKREINCLMNLNHPNCIKFYGVTVIPPFSIITKFIPHGSLYDLLVNNP-DD-------LTPLRRMKIAIGITRGLEYLDLVH--VLHRDIKPQNILI
. .. .|. .. .||||| .. .|.. | |. ... ..|||.||..| |.  |        ...  . |||. | .|.|||   .  ..||| |. |||.
FREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---DEND---------HAVLCDFGLSR---SFGPK-MTAELGTIAYMAPELMGNS-FTSYDSSCDTYSFGILLYDLLMGPAKYMQMFP-------VQIAM
   ..|.         .| ..|||.||   .|...     .|.. .|||| |..    .|.   |.||||..|..|| .   ... ..         .  
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

RVLKEKYRPELPND--NH-----SFCELITQCWSQNPRKRPKMSVIRKKLED
   .|. || .|..  ..     ....||..||...|.|||..| | |.|..
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 83791.m00055.AA S_TKc 194-441 26 1.4e-57 198.48 SMART 1-220 (231) Show / Hide 
Range on Protein: 194-441
Range on HMM: 1-220/231
Sequence Identity: 26% (69 aa)

FTKQEQIGAGAYAKVFKAIFNATNETIAIKELTRIDMPPRKLFTLKREINCLMNLNHPNCIKFYGVTVIPPFSIITKFIPH--GSLYDLLVNNPDD----
... ..|| ||..||.|.. . |..  |||..           ...|||..|.. .||| .|.|.| .   . ... ....  |.|.|......      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTPLRRMKIAIGITRGLEYLDLVHVLHRDIKPQNILIDENDHAVLCDFGLSRSFGPKMTAELGTIAYMAPELMGNSFTSYDS-SCDTYSFGILLYDLLM
 ... .  ...  | ..|||.   ...|||.||.|||.||  |  .|||||.| .    |   ||  |||||..     .|.  .|| .|.|..|| .| 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLC

GPAKYMQMFPVQIAMRVLKEKYRPELPNDNHSFCELITQCWSQNPRKRPKMSVIRK
|   .     .|  .....           ......| .|.  .|.|||    . .
GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase 83791.m00055.AA STE 194-437 21 1.7e-48 167.4 In-house 1-349 (359) Show / Hide 
Range on Protein: 194-437
Range on HMM: 1-349/359
Sequence Identity: 21% (77 aa)

FTKQEQIGAGAYAKVFKAIFN------ATNET---------IAIKELTRIDMPP---------------RKLFTLKREINCLMNLN--HPNCIKFYGVTV
....|.|| ||. .|.||. .       |.|.         .|||..   .  .                ..  ...||. ....|  ||| .|.||  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

IPP--------FSIITKFIPHGSLYDLLVNNPDDLTPLR-------------RMKIAIGITRG-LEYLDLVHVLHRDIKPQNILIDENDHAVLCDFGLSR
             |.  ... ||| |.. ..   . ||                .|.  | .| |.||   |. ||||||.|||.     . |||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SFGP-------------------KMTAELGTIAYMAPELMGNS----FTSYDSSCDTYSFGILLYDLLMGPAKYMQMFPVQIAMRVLKE-----------
.. .                   | .   ||  .|||| . .        || .|| .|.|...  .. |   .. | | .  .. ...           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---KYRPELPND--------------------NHSFCELITQCWSQNPRKRPKMS
   .  | ||..                      .|.. | .|   .|.|||. |
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTAS
Kinase 83791.m00055.AA Dicty4 194-445 28 1.5e-47 156.77 In-house 1-277 (277) Show / Hide 
Range on Protein: 194-445
Range on HMM: 1-277/277
Sequence Identity: 28% (80 aa)

FTKQEQIGAGAYAKVFKAIFNATNETIAIKEL--TRIDMPPRKLFTLKREINCLMNLNHPNCIKFYGVTV----IP-PFSIITKFIPHGSLYDLLVN---
 .... || |....|.|..   .    |.| |  . ..     |  ...|.. . .. ||| ..|.|       .|  ..| | . | |.|| || .   
INIEQRIGKGSFGEVYKGTWRGKE--VAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

-----NPDDLTPLRR-MKIAIGITRGLEYLDL--VHVLHRDIKPQNILIDENDHAVLCDFGLSR------SFGPKMTAELGTIAYMAPELMGNSFTSYDS
      . |..  .| |..|. . ||. .|    . ..|||.|. |.|.|.|  .  ||||||.      ... ....  || ..|||| |   . .|..
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVM--MHQPYNE

SCDTYSFGILLYDLLMGPAKYM--QMFPVQIAMRVLKEKYRPELPND-NHSFCELITQCWSQNPRKRPKMSVIRKK--LED
. | |||||.|. .| . . |    | ..|..  |  .| ||..|..   |. .||. ||. .| .|| .. | ..  || 
KADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 83791.m00055.AA Dicty4-Unclassified 197-443 30 1.5e-44 150.51 In-house 4-263 (263) Show / Hide 
Range on Protein: 197-443
Range on HMM: 4-263/263
Sequence Identity: 30% (81 aa)

QEQIGAGAYAKVFKAIFNATNETIAIKELTRIDMPPR--KLFTLKREINCLMNLNHPNCIKFYGVTVIP-----PFSIITKFIPHGSLYDLLV------N
   || |. .|| | .    .  .|.| .       |   .   |.|.  |  . ||| .| ||  . |      . |.. |.. | |  .        .
DQFIGKGHFSKVHKGNWKGKD--VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

NPDDLTPLRRMKIAIGITRGLEYLDLVHVLHRDIKPQNILIDENDHAVLCDFGLSR--SFGPKMTAELGTIAYMAPE-LMGNSFTSYDSSCDTYSFGILL
 |  |     .|.|. | .|. .|  . . |||||  |||.| .  .   |||.||  .|   ||.  || .  .|| ||.    || .  | ||....|
QPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHE---SYNQKSDVYSYAMML

YDLLMGPAKYMQMF-PVQIAMRVLKEKYRPELPNDNHSFC-ELITQCWSQNPRKRPKMSVIRKKL
| |. |   |.    .. .|  |   | ||..|     |   ||  ||.  |.||| |  | ..|
YELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 83791.m00055.AA TyrKc 194-443 23 3.8e-44 153.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 194-443
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

FTKQEQIGAGAYAKVFKAIFNATNETIAIKELTRIDMPPRKLFTLKREINCLMNL--NHPNCIKFYGVTVI--------PPFSIITKFIPHGSLYDLLVN
 |. ...| ||. .|.|.. .   .. |.| |         .  . ||.. ...|  .||| ...||| .         .|  |.. . |||.| | | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NPDDLTPLRRMKIAIGITRGLEYLDLVHVLHRDIKPQNILIDENDHAVLCDFGLSRSFGPK--------MTAE----LGT----IAYMAPELMGNSFTSY
. ..|..    .... | .| |||   .. |||.   |.|..|| ..  .||||||  . .        .        |     |  |||| .   .  .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKF

DSSCDTYSFGILLYDLLMGPAKYMQM-----FPVQIAMRVLKEKYRPELPND---------NHSFCELITQCWSQNPRKRPKMSVIRKKL
 .  | .|||.... ..   ..          . | ... .|. ||.. | .              ....|||  .| .|| .| |....
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 83791.m00055.AA Pkinase 194-443 24 1.2e-42 151.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 194-443
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

FTKQEQIGAGAYAKVFKAIFNATNETIAIKELTRIDMPPRKLFTLKR--EINCLMNLNHPNCIKFYGVTV-IPPFSIITKFIPHG----SLYDLLV---N
... ..||.|....|.|..   |... |.|.. . .  . |. |. |  ||  . .||||| ...|..    .   ... . ..|    .|.|..    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NPDDL--TPLRRMKIAIGITRGLEYLDLVHVLHRDIKPQNILIDENDHA----VLCDFGLS----RSFGPKMTAELGTIAYMAPELMGNSFTSYDSSCDT
..  .  ..    ...  | |||||.    ..|||.||.|||||.|.|      .|||||.       .. ||   ||. |||||.   . . |....| 
GC--FYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDM

YSFGILLYDLLMG----PAK-----YMQMFPVQIAMRVLKEKYRPELPNDN-----------------HSFCELITQCWSQNPRKRPKMSVIRKK--L
.|.|..|| .| |    | .     . ||. ..  |.   .  .|.. .                    .....|. |. ..| |||    | .   .
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 83791.m00055.AA TK 194-443 14 2.4e-42 139.27 In-house 1-486 (486) Show / Hide 
Range on Protein: 194-443
Range on HMM: 1-486/486
Sequence Identity: 14% (71 aa)

FTKQEQIGAGAYA---KVFKAIFNATN-------------------------ETIAIKELTRI-DMPPRKLFT--------------LKREINCLMN--L
 |  ...|.|..    .|.|.. .  |                         .. |.| |.   .| ..  |               . .|.  ...  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHPNCIKFYGVTVI-------------PPFSIITKFIPHGS----LYDLLVNNPDD--------------------------------------------
.||| ...||| .              .|. |.. . |||.    | | | .....                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTPLRRMKIAIGITRGLEYLDLV------HVLHRDIKPQNILIDENDH-----------AVLCDFG---
                               ||. ... ..  | .|.|||         .. |||.   |.|..||..           . ..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRSFGP-----KMT------------------------AELGTIAYMAPELMGNS-------FTSYDSSCDTYSFGILLYDLLMGP-AKYMQMF
     |.|  ..     ...                             | .|||| .          .  . .  | .|||.|.. ...   . |  . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PV---------QIAMRVLKE------------KYRPELP---NDN--------------HSFCELITQCWSQNPRKRPKMSVIRKKL
.          |  |. |..             || ..|   .                  . .|..|||. .|..|| .| ....|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 83791.m00055.AA CMGC 194-386 18 8.4e-39 124.49 In-house 1-331 (513) Show / Hide 
Range on Protein: 194-386
Range on HMM: 1-331/513
Sequence Identity: 18% (61 aa)

FTKQEQIGAGAYAKVFKAIF--------------NATNETIAIKELTRIDMPPRKL---------FTLKREINCLMNLN-----------------HPNC
... ..|| |.|..|.|..               . ||| .||| . .  ..  ..         ..  ||| .|..||                 |.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IKFYGVTVIP------------------PFSIITKFIPHGSLYDLLVNNPD--------DLTPLR------------RMKIA------IGITRGLE--YL
.| | . . .                   . ... ...| .||... ||..         |..                ..         | |||.  |.
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

DLVH--VLHRDIKPQNILIDEN--------------------DHAVLCDFGLSRSFGPK------------------------MTAELGTIAYMAPELMG
      ..|||.||.||||..|                    ..  .|||||.|...|                         .| .  |  | |||.. 
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

NS--------FTSYDSSCDTYSFGILLYDLLMG
..        .. |....|  |.|  .. ...|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTG
Kinase 83791.m00055.AA Ciliate-E2 194-386 21 1.1e-35 119.9 In-house 1-292 (365) Show / Hide 
Range on Protein: 194-386
Range on HMM: 1-292/365
Sequence Identity: 21% (64 aa)

FTKQEQIGAGAYAKVFKAIFNATNETIAIKELTRID-------------------MPPRKLFTLKREINCLM----------------NLNHPNCIKFYG
. ....|| |....|.|.    ... .|||  .                      | ..... .|.||. ..                .||||| ||.| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VTVIPPFS--------IITKFIPHGSLYDLLVNNPD----------DLTPLRRMKIAIGITR---------------GLEYLDLVH-VLHRDIKPQNILI
.     |         ... .. .|.|.|.. ||.            .|   . .|   |..               .||||   . ..||||||.|||.
C-----FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF

DENDHAVLCDFGLSRSFGPKMTAEL----------------------------------GTIAYMAPELMGNSFTS-------YDSSCDTYSFGILLYDL
       ..|||||. . ...  ..                                  ||  |||||  ..   .       || .|| .|.|..|| .
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

LMG
|.|
LFG
Kinase 83791.m00055.AA Pkinase_Tyr 194-381 27 1.1e-32 111.3 Pfam 1-205 (270) Show / Hide 
Range on Protein: 194-381
Range on HMM: 1-205/270
Sequence Identity: 27% (58 aa)

FTKQEQIGAGAYAKVFKAIFN----ATNETIAIKELTRIDMPPRK--LFTLKREINCLMNL-NHPNCIKFYGVTV-I-PP--FSIITKFIPHGSLYDLLV
 |. ...|.||. .|.|.. .     |. . |.| | . .  ..   .  . ||.. ...| .||| ...||| .    |    |.. . |||.|.| | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NN---PDDLTPLRRMKIAIGITRGLEYLDLVHVLHRDIKPQNILIDENDHAVLCDFGLSRSF-----G-PKMTAELGTIAYMAPE-LMGNSFTSYDSSCD
..   .. ||. .  .... | .|.|||   .  |||.   |.|..|| ..  |||||.|          | .     |  |||| .. .    . .  |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK---FTTKSD

TYSFGILLY
 .|||.|..
VWSFGVLMW
Kinase 83791.m00055.AA Pkinase_Tyr 420-443 41 1e-05 20.0 Pfam 247-270 (270) Show / Hide 
Range on Protein: 420-443
Range on HMM: 247-270/270
Sequence Identity: 41% (10 aa)

ELITQCWSQNPRKRPKMSVIRKKL
.|..||| ..| .|| .| |. .|
DLMKQCWHYDPEDRPTFSEIHEQL