Gene 84773.m00045 (T.vaginalis)

84773.m00045

Species: T.vaginalis
Alias: 84773.m00045, TvagK0174
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
84773.m00045.AA Protein None 306 None Fasta, JSON
84773.m00045.kin_dom Protein Kinase Domain None 242 None Fasta, JSON

Protein domain

Protein domains of 84773.m00045.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 84773.m00045.AA S_TKc 14-255 28 6.9e-72 246.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-231/231
Sequence Identity: 28% (73 aa)

IEYQSTIAQGGFGVVFYVYSTHYHSFFALKKIPDVSFNESEIECIKQIDDPHIVSLYQYYKFDNSIYLLMEYCPS---DLEKYLKSNRH------ISEIQ
 |   .| .|.||.|. .. .. .  .|.|.|.     ..||.. |. . |.|| || ..   ...|. ||||.    || .|.|....      ..| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LQKYIYDAVKAIHQCHAKGIAHCDIKPSNFMFDKYGRLKIGDFGLSTSMSELVHSNRGTPVFMAPETFMKNQYCPIKADIWSLGVIIYYMATLQFPFFGE
 ..|.|  ..|.  || .|| |.|.||.| ..|.  ..||.||||.. .    ..  ||| .|||| .   .| . |.|.||.|.|.| |.. . ||   
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--

TRSALIQNIIRTRYNDDSVEDGRLREVISSCLDPNPDNRLSTEDILK-------MPYF
.  .....|           .  ... |. ||. .|..|..  ..|.       .|.|
QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84773.m00045.AA CAMK 19-255 17 1.5e-65 209.91 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-255
Range on HMM: 1-425/425
Sequence Identity: 17% (74 aa)

TIAQGGFGVVFYVYSTHYH------------SFFALKKIP-------------------------------DVSFN--ESEIECIKQ-------IDDPHI
|. .|.||.|. .. ..                .| | |.                               ...    ..|||. |.       .| |.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLYQYYK------------FDNS--------IYLLM---EYCPS-----DLEKYLKSN---------------RHISEIQLQKYIYDAVKAIHQCHAKG
..||..|             . .         .|. |   |||.      ||  |....               ....| . ..|.   . |.| || ..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHCDIKPSNFMFDKY-----------------GRLKIGDFGLSTSMSE--------------------------LVHSNRGTPVFMA-PETFMK-----
|.|.|.|| | ..|.                  . .|| |||... . .                          . .   ||| .|| || . .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------NQYCPIKADIWSLGVIIYYMATLQFPFFGE-------------TRSALIQNIIRTRYN-DDSVEDG-----------------------RLR
        ..|.. |.|.||.||| | | .  .|| |.             . . | ..|.. .|. ...  ..                         .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

EVISSCLDPNPDNRLSTEDILKMPYF
  |...| ..|..|.. |..|. | .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 84773.m00045.AA Pkinase 14-255 27 2.8e-64 224.68 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-293/293
Sequence Identity: 27% (80 aa)

IEYQSTIAQGGFGVVFYVYSTHYHSFFALKKIPDVSFNE---------SEIECIKQIDDPHIVSLYQYYKFDNSIYLLMEYCPS-----DLEKYLK--SN
..  ..| .|.||.|.  .   .   .|.|.|. .. ..         |||.  | .. |.|| || ..  ...||. ||||.      ||  |..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RHI--SEIQLQKYIYDAVKAIHQCHAKGIAHCDIKPSNFMFDKYGRL----KIGDFGLS----TSMSELVHSNRGTPVFMAPETFMKNQYCPIKADIWSL
. .  || ....|.|  ....  ||..|| |.|.||.|...|. | .    ||.||||.    .  ..  ..  ||| .||||  ...|| . |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVIIYYMATLQFPFFGE------TRSALIQNIIRTRYNDDSVED---------------------GRLREVISSCLDPNPDNRLSTEDILKMPYF
|.|.|.|.. ..|| |.      .  ..|..| ....  |. ..                       ....|..||...|  |.. |.||. |.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 84773.m00045.AA CAMKL 42-255 26 2.6e-54 171.63 In-house 38-297 (297) Show / Hide 
Range on Protein: 42-255
Range on HMM: 38-297/297
Sequence Identity: 26% (70 aa)

LKKIPDVSFN------------ESEIECIKQID---DPHIVSLYQYYKFDNS------IYLLMEYCPSD---LEKYLKSNRH----ISEIQLQKYIYDAV
....| .. |            . ||.. |...    |.|..||. .  ..       ||| ||||..    |  |.....|    ..| . ..|    |
IWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIV

KAIHQCHAKGIAHCDIKPSNFMFDKYG--RLKIGDFGLSTS---M----SELVHSNRGTPVFMAPETFMK--NQYCPIKADIWSLGVIIYYMATLQFPFF
 |.. || .||.| |||| | ..|. |   .|| |||.|.    .     .. .   |.| .|||| | .   .|.  |.||||.||| | | . ..|| 
SAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFD

GET---------RSALIQNIIRTRYNDDSVEDGRLREVISSCLDPNPDNRLSTEDILKMPYF
..|         .  .....  ....  .  . ..|  |.. | .||. | . ..|.. | .
DDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 84773.m00045.AA Ciliate-E2 14-255 20 2.3e-52 178.08 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-365/365
Sequence Identity: 20% (79 aa)

IEYQSTIAQGGFGVVFYV--YSTHYHS---------------------FFALKKI--PDVSFNESEIECIK----------------QIDDPHIVSLYQY
.. .  | ||.||.|...  ... . .                     ..|.| .   .. . ..||  ..                |.. |.|. .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YK--FDNSIYLLMEYCPS-DLEKYLKSNRHIS-----------EIQLQKYIYDAVK---------------AIHQCHAKG-IAHCDIKPSNFMFDKYGRL
..   ||.||| ||||   ||..|.|.|.. .           | . .....  ..               |.. .| |. | | ||||.| .|     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIGDFGLST------------SMSE----------------------LVHSNRGTPVFMAPETFMKNQY--------CPIKADIWSLGVIIYYMATLQFP
|| |||||.            ....                      ....  ||| .|||| ... .|           |.||||||||.|.| . ..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FFGETRSALIQNIIRTRYN------------------DDSVEDGRLREVISS----CLDPNPDNRLS-TEDILKMPYF
|        .|.|.   ..                  .    .      |.     .|. .|..|..  |.||. |.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 84773.m00045.AA ULK 14-255 22 2.8e-51 176.66 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-324/324
Sequence Identity: 22% (74 aa)

IEYQSTIAQGGFG-VVFYVYSTHYH---SFFALKKIP-----DVSFN----------ESEIECIKQID---DPH--IVSLYQYYKFD--NSIYLLMEYCP
..    . .| || .|.  .    .    ..| |.|.     . . .          ..||. .|...    |.  || || ... .  | ||. ||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

S-DLEKYLKSNRH---------ISEIQLQKYIYDAVKAIHQCHAKGIAHCDIKPSNFMFDKY------------GRLKIGDFGLSTSMSE------LVHS
  |||.|.| |..         .|| . ...... . .    | ..| |.||||.| .  .             |.|||.|||.. .  .      . ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

NR------GTPVFMAPETFM----KNQYCPIKADIWSLGVIIYYMATLQFPFFGETRSALI----------------QNIIRTRYN---DDSVEDGRLRE
        ||| .|||. ..    . .|. .|.||||||.|.|.| . . |||.   . ..                 .    ...   .| .    ...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VISSCLDPNPDNRLSTEDILKMPYF
 |. .|  ... | | |.|...| |
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 84773.m00045.AA ULK 14-255 22 1.1e-50 174.76 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-329/329
Sequence Identity: 22% (74 aa)

IEYQSTIAQGGFGVVFYVYSTHYH----SFFALKKIP---DVSFN------------ESEIECIKQIDDP--------HIVSLYQYYKFD--NSIYLLME
..    . .| ||.|.  .    .      .| |.|.      .|            ..||. .|....|        .|| || ... .  | ||. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPS-DLEKYLKSNRH----------ISEIQLQKYIYDAVKAIHQCHAKGIAHCDIKPSNFMFDKY------------GRLKIGDFGLSTSMSE------
||.  |||.|.| |..          .|| . ...... . .    | ..| |.||||.| . ..             |.|||.|||.. ....      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LVHSNR------GTPVFMAPETFM----KNQYCPIKADIWSLGVIIYYMATLQFPFFGETRSALI-----QNIIR------------TRYN---DDSVED
. ..        ||| .|||. ..    . .|.  |.||||||.|.|.| . . ||..   . ..     ..|              ....   .| .  
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

GRLREVISSCLDPNPDNRLSTEDILKMPYF
  ... |. .|  ... | | |.....| |
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 84773.m00045.AA Ciliate-E2-Unclassified 14-255 22 2e-49 169.57 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-352/352
Sequence Identity: 22% (80 aa)

IEYQSTIAQGGFGVVFYVYS-THYHSFFALKKIP--------------DVSFNESEIECIK----------------QIDDPHIVSLYQYYKFDNSIYLL
 . . .| |||||.|. ..   ..  ..|.| .               . .... |....|                ....|.|| .. . . .. ||. 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCPS-DLEKYLKSNRH-----------------ISEIQLQ-----KYIYDAVKAIHQCHAKG-IAHCDIKPSNFMFDKYG---RLKIGDFGLST---S
||||.  ||..|.|.. .                 ..| | .     .|..  .... ..| |. | | ||||.| .||. |   ..|| |||.|    .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

M---------------SELVHSNRGTPVFM----APETFMK-NQYCP--IKADIWSLGVIIYYMATLQFPFFGETRSA----------------LIQNII
.               ... ... ||| .|    ||| ... |.. .  .|.||||||||.|.| . ..||.....                  |.|||.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

RTRYNDDSVE--------DGRLREVIS----SCLDPNPDNRLSTEDILKMPYF
   .. .. .        .    . |.    ..|. ||..|.. |.||. |.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 84773.m00045.AA MARK 19-255 33 1.1e-44 144.04 In-house 6-262 (262) Show / Hide 
Range on Protein: 19-255
Range on HMM: 6-262/262
Sequence Identity: 33% (86 aa)

TIAQGGFGVVFYVYSTHYHSFFALKKIP-----D---VSFNESEIECIKQIDDPHIVSLYQYYK--FDNS-IYLLMEYCPS-DLEKYLKSN--RHISEIQ
|| .|....|  . ..|..  .|.| ..     |    .  ..|||  |..| |.|..|...      .  ||| |||... .|  |.|.   ....|  
TIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEE

LQKYIYDAVKAIHQCHAKGIAHCDIKPSNFMFDKYG--RLKIGDFGLSTSM--SELVHSNRGTPVFMAPETFMKNQYCPIKADIWSLGVIIYYMATLQFP
  ..    | |.. || |.|.|.|||| | . |. |    || |||.|.     ..  .  ||| .|||| | |  |.  |.|||||||. |.| . .||
ARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFP

FFGET--RSALIQNIIRTRYN-DDSVEDGRLREVISSCLDPNPDNRLSTEDILKMPYF
| | |     | ..| | .|   . | .. .|  |.. | .||. | . |.|.| | .
FDGDTQDYKELYKKILRGKYDIPCHVSKE-CRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 84773.m00045.AA STE 14-255 17 2.2e-42 147.11 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-359/359
Sequence Identity: 17% (65 aa)

IEYQSTIAQGGFGVVFYVYSTH---------------YHSFFALKKIP----------------------DVSFNESEIECIKQID--DPHIVSLYQYYK
 | .. | .|.||.|.. .  .                . ..| |...                      ..   . ||.  |. .   |.||  | .| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FD-------NSIYLLMEYCP-SDLEKYLKSN--------------RHISEIQLQKYIYDAVKA-IHQCHAKGIAHCDIKPSNFMFDKYGRLKIGDFGLST
 .       ..... |||..   |.. .|..               ...| |. ..... .|.  .  | ..| | ||||.| ..      |. |||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SMSE-------------------LVHSNRGTPVFMAPETFMK-----NQYCPIKADIWSLGVIIYYMATLQFPFFGETRSALIQNIIRT-----------
....                      .  ||| .||||  ..     .. . .|.||||||  |  ||| . |.. ..    . .|..            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---------RYNDDSVED---------------GRLREVISSCLDPNPDNRLSTEDILK--MPYF
           . ...|                  ... |. ||. .|..| .... ||   | .
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 84773.m00045.AA CMGC 14-202 17 2.4e-39 126.33 In-house 1-343 (513) Show / Hide 
Range on Protein: 14-202
Range on HMM: 1-343/513
Sequence Identity: 17% (62 aa)

IEYQSTIAQGGFGVVFYVYSTH--------------YHSFFALKKIPDVSFNE-----------------SEIECIKQI-----------------DDPH
 |  . | .| .|||.  . ..              .  . |.|||  .  .|                  ||.. |..                 ....
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVSLYQYYKFDN-----------------SIYLLMEYCPSDLEKYLKSNR---------HISEIQ------------LQKYI------YDAVKAIH--QC
||.|| .....|                 ..|| .||.. || .|.|.|.         . || .             ....      |   ....   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HAKG--IAHCDIKPSNFMFD--------------------KYGRLKIGDFGLSTSMSEL------------------------VHSNRGTPVFMAPETFM
| ..  | |.|.||.| ...                    | |||||.||||... ..                           ..  |    |||  .
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

KN---------QYCPIKADIWSLGVIIYYMATL-------QFPFF
           ..   . |.||.| |.. | |          |.|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLF
Kinase 84773.m00045.AA NEK 15-255 27 1.4e-37 130.11 In-house 2-286 (286) Show / Hide 
Range on Protein: 15-255
Range on HMM: 2-286/286
Sequence Identity: 27% (79 aa)

EYQSTIAQGGFGVVFYVYST--HYH---SFFALKKIPDVSF------NE---SEIECIKQIDDPHIVSLYQYYKFDN--SIYLLMEYCPS--DLEKY---
|.. .| || ||.|. | ..    |   .....|||  ..        .   .|.   ||.. |.||. |  .  ..  ...  ||||    ||..    
EIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

LKSNR----HISEIQLQKYIYDAVKAIHQCHAK-----GIAHCDIKPSNFMFDKYGR----LKIGDFGLSTSMS-E--LVHS-NRGTPVFMAPETFMKNQ
.| ..    ...| |  .. .  ..|.. .| .      | | ||||.| . .| ..    .||||||.|  .. .  . ..   ||| .|.|| .    
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YCPIKADIWSLGVIIYYMATLQF--PFFGE--TRSALIQNIIRT-RYNDDS-V--EDGRLREVISSCLDPNPDNRLSTEDILKMPYF
|   |.||||||...| |.||.   || ..     .|. .|..   |.  .        |...||..| ..|..| |...||.||. 
YNN-KSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 84773.m00045.AA TyrKc 14-255 19 1.6e-12 -20.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-280/280
Sequence Identity: 19% (55 aa)

IEYQSTIAQGGFGVVFY-VYSTHYHSFFALKKIPDVSFNE---SEIECIKQI--DDPHIVSLYQYYKFD-------NSIYLLMEYCPS-DLEKYLKSNRH
|.   ..  | ||.|.  ...       | |.. . .  |   .|..  ...  . |.|| || .   .         ....|||.|  || .||...|.
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-ISEIQLQKYIYDAVKAIHQCHAKGIAHCDIKPSNFMFDKYGRLKIGDFGLSTSMSEL--------VHSN----RGT---PVF-MAPETFMKNQYCPIKA
 ..  .| .. ... .     | |.. | |.   | . .. .. ||.|||||    .         . .      |    |.  ||||..... .  .| 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS

DIWSLGVIIYYMATLQFPFFGE-----TRSALIQNIIRTRYNDDSVED----------GRLREVISSCLDPNPDNRLSTEDILKMPYF
|.|| || .. . |.  .   .        . . . ....|  .  ..            . .....| . .|..| . ..|    .|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 84773.m00045.AA CMGC 232-255 37 9e-06 13.9 In-house 490-513 (513) Show / Hide 
Range on Protein: 232-255
Range on HMM: 490-513/513
Sequence Identity: 37% (9 aa)

ISSCLDPNPDNRLSTEDILKMPYF
.. .|  .||.|.. |..|..|||
LKKMLQYDPDKRITAEQALQHPYF
Kinase 84773.m00045.AA Pkinase_Tyr 143-189 32 0.003527 11.39 Pfam 151-202 (270) Show / Hide 
Range on Protein: 143-189
Range on HMM: 151-202/270
Sequence Identity: 32% (17 aa)

KIGDFGLSTSM----SE-LVHSNRGTPVF-MAPETFMKNQYCPIKADIWSLGV
||.||||.  .        ....   |.. |||| .. .  . .| |.|| ||
KICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGV
Kinase 84773.m00045.AA Pkinase_Tyr 53-111 27 0.019701 8.86 Pfam 52-119 (270) Show / Hide 
Range on Protein: 53-111
Range on HMM: 52-119/270
Sequence Identity: 27% (19 aa)

SEIECIKQI-DDPHIVSLYQYYK-FDNS--IYLLMEYCPS-DLEKYLKS----NRHISEIQLQKYIYD
.|..  ||. . |.||.||      . .  ||. |||.|  || .||..    .....  .| .. ..
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQ