93904.m00234

Species: T.vaginalis
Alias: 93904.m00234, TvagK1027
External Links:
Annotation:

Classification

Group: Other
Family: TLK

Sequence

Name Sequence Type Origin Length Description Download
93904.m00234.AA Protein None 501 None Fasta, JSON
93904.m00234.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of 93904.m00234.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 93904.m00234.AA S_TKc 213-481 27 6.8e-66 226.14 SMART 1-231 (231) Show / Hide
Range on Protein: 213-481
Range on HMM: 1-231/231
Sequence Identity: 27% (80 aa)

IQLIEPIGRGGFAEVWKAWDYETAQIVAVKVIELPKNVNLAQFANHLKREIDIMTVTEHKNVIKILRYFYLADNTVAYVMEFAGG--GDLNGILRKVR--
 .....||.|.|..|.|... .| .|||.|.|            .|..|||.|.    |.|..|.. .|.   . .  |||...|  |||  ...| .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LTESEAHSIIKQVIDGLLALKSKPSDTSEVIIHYDLKPANILFDENFVPKIADFGLSKIADEGKSIMQSTPGTGTVGYTAPETFTSNNKVSL-ST
     ..| .| ....|....|  . |.       ||| ||||.|||.||  . ||.||||...          |   ||  | ||| .    . .  . 
GLRFPFPE-HARFYMYQICCALEYCHSHG------IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCKC

DTWSLGIIYYEMMT------NDNELKRKIQTVDAQTCEKIVNESLDDKKVKSKLSEKGQEFIKICLRKDPKDRPTIKALAE-------MDYI
| ||.|.| |||..      ..... .||                         |. . .||. ||.|||..|||.  . .       . ..
DWWSCGCILYEMLCGYPPFPQMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Pkinase 93904.m00234.AA Pkinase 213-481 27 1.6e-57 202.24 Pfam 1-293 (293) Show / Hide
Range on Protein: 213-481
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

IQLIEPIGRGGFAEVWKAWDYETAQIVAVKVIELPKNVNLAQFANHLK-REIDIMTVTEHKNVIKILRYFYLADNTVAYVMEFAGGG----DLNGILR--
......||.|.|..|.|. .  | .|||||.|... . .  .  .|.. .|| ||    |.|.......|.  .. .  |||...||    ||  ...  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTW

-KVRL--TESEAHSIIKQVIDGLLALKSKPSDTSEVIIHYDLKPANILFDENFVP----KIADFGLSKIADEGKSIMQSTPGTGTVGYTAPETFTSNNKV
 . ..  .| |. ....|.. ||  . |.       ||| ||||.|||.|.| ..    ||.||||.| .|   .    |  .|| .| |||   .... 
RHGCFYFSEWECKFYMYQILRGLEYCHSM------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

SLSTDTWSLGIIYYEMMTNDNELKRK-------IQTVDAQTCEKIVNESLDDK---------------KVKSKLSEKGQEFIKICLRKDPKDRPTIKALA
. . | ||.|.| |||..     . .        . . ... .... .. . .               ..  ..|| ...||| ||.||||.|||.. . 
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQIL

EMDYI
. ...
QHPWF

Kinase 93904.m00234.AA Ciliate-E2 213-481 23 4e-49 166.77 In-house 1-365 (365) Show / Hide
Range on Protein: 213-481
Range on HMM: 1-365/365
Sequence Identity: 23% (91 aa)

IQLIEPIGRGGFAEVWKAWDYETAQIVA----------------VKVIELPKNVNLAQFANHLKREIDIMTVTE----------------HKNVIKILRY
. .|. ||.|.|. |.|. .... . .|                ||. .  ....  .  ...|.||.||   .                |.|.||.  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FYL-ADNTVAYVMEFAGGGDLNGILRKV------------RLTESEAHSIIKQVID---------------GLLALKSKPSDTSEV-IIHYDLKPANILF
|.   ||.. .|||.. ||||  ....             ..|| |.  |.||...               .|  |.||        ||| |.|| ||||
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSK------NNIIHRDIKPENILF

DENFVPKIADFGLSKIAD----------------EGKSIMQSTPG--------------TGTVGYTAPETFTSNNK--------VSLSTDTWSLGIIYYE
     .||.||||||..|                . |. .  |||               || || ||| . . .          . . | ||||.| ||
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

MMTNDN--ELKRKIQTVDAQTCEKIVNESLDDKKVKSK------LSEKGQEFIKI----CLRKDPKDRPT-IKALAEMDYI
|...    . . | . .| .  |.. . .. .. .  |      .|.... .||     .| |||. |.| .. . .  ..
MLFGKPPFQQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 93904.m00234.AA ULK 213-481 25 1.8e-44 154.1 In-house 1-324 (324) Show / Hide
Range on Protein: 213-481
Range on HMM: 1-324/324
Sequence Identity: 25% (86 aa)

IQLIEPIGRGGFA-EVWKAWDYET---AQIVAVKVIELPKNVNLAQFAN------HLKREIDIMTVTE---HKN--VIKILRYFYLAD-NTVAYVMEFAG
..|.. .| | |.  | |. . .|    |.||.|.|.. |  .  . ..       ||.|| ||       |.|  ..| . .|. .. | .  .||.  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLNGILRKV----------RLTESEAHSIIKQVIDGLLALKSKPSDTSEVIIHYDLKPANILFDENF------------VPKIADFGLSKIAD---EG
||||  .. |           ||.|.|| ...|| . |. .| ..       ||| |.||.|||  ...            | ||||||..|. |   . 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHN------IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNME

KSIM-----QSTPGT---GTVGYTAPETFT---SNNKVSLS-TDTWSLGIIYYEMMT---N----DNELK----RKIQT-VDAQTCEKIV--NESLDDKK
. ..     .    .   ||  | ||. .     . . . . .| ||||.|.||| .         |...    . |.    .|   .|   |. .. .|
QQMCQTCVNE----KRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGK-EQ---QIYIKNQPIQFPK

VK--SKLSEKGQEFIKICLRKDPKDRPTIKALAEMDYI
..   |.|.. ...|. .| .|.||| ..  . ..  .
PPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF

Kinase 93904.m00234.AA ULK 213-481 25 2e-44 153.01 In-house 1-329 (329) Show / Hide
Range on Protein: 213-481
Range on HMM: 1-329/329
Sequence Identity: 25% (87 aa)

IQLIEPIGRGGFAEVWKAWDYET----AQIVAVKVIELPKNVNLAQFAN------HLKREIDIMTVTE----HKN----VIKILRYFYLAD-NTVAYVME
..|.. .| | |. | |. . .|    ...||.|.|.. |  .  . ..       ||.||.||        |||    ..| . .|. .. | .  .||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FAGGGDLNGILRKV-----------RLTESEAHSIIKQVIDGLLALKSKPSDTSEVIIHYDLKPANILFDENF------------VPKIADFGLSKIADE
.  ||||  .. |            ||.|.|| ...|| . |. .| ..       ||| |.||.||| ....            | ||||||..|  |.
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHN------IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDN

G---KSIMQSTPGT------GTVGYTAPETFT---SNNKVSLS-TDTWSLGIIYYEMMT---------NDNELKRKIQTVDAQTCEK--IVNESLDDKKV
.   . .|...  .      ||  | ||. .     . . . . .| ||||.|.||| .         ||  |. ... .. .   .  | .. |. .|.
DNMEQQMMMTC--VNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKD

--KSKLSEKGQEFIKICLRKDPKDRPTIKALAEMDYI
  . ..|.. ...|. .| .|.||| ..  | ..  .
GNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 93904.m00234.AA CAMK 218-481 19 1e-43 138.28 In-house 1-425 (425) Show / Hide
Range on Protein: 218-481
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

PIGRGGFAEVWKAWDYETA------------QIVAVKVIELPKNVNL-----------------------AQFANH-LKREIDIMTV-------TEHKNV
 .|||.|..| .. . .|             | ||.|.|.  |  .                         ..  . ..|||.||           |.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKILRYFYLADN--------TVAY-----------VM---EFAGGG----DLNGILRKV----------------RLTESEAHSIIKQVIDGLLALKSKP
||.. ..  ...        |  .           ||   |.. ||    ||   ...                 |.||.||. ...|.....  . |. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH-

SDTSEVIIHYDLKPANILFDEN-----------------FVPKIADFGLSKIADEGK----------------------SIMQSTPGTGTVGYTA-PETF
      |.| |||| |||.|.|                 .  ||.|||.... |.|.                        . .|.  || .| | || .
-----NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTF-CGTPEYMAAPEVL

TS-------------NNKVSLSTDTWSLGIIYYEMMTN----DNELKRKIQT------VDAQTCEKIVNESLD-DKKVKSK-------------------
 .             .  .. ..| ||.|.| | | .     . .    |         | ...||| .   | . .  |.                   
NGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH

-LSEKGQEFIKICLRKDPKDRPTIKALAEMDYI
 .|.  . .|. .|..||..|.||.   .   .
FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 93904.m00234.AA Ciliate-E2-Unclassified 213-481 20 2.2e-43 148.34 In-house 1-352 (352) Show / Hide
Range on Protein: 213-481
Range on HMM: 1-352/352
Sequence Identity: 20% (73 aa)

IQLIEPIGRGGFAEVWKAWDYETAQIV-----AVKVIELPKNVNLAQFANHLKREIDIMTV----------------TEHKNVIKILRYFYLA-DNTVAY
  .|. ||.|||..|.|. . ..   .     . |...  ..  . .  ...  .. ..                    |.. ...  ...   ....  
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEFAGGGDLNGILRK------------------VRLTESEAH-----SIIKQVIDGL-LALKSKPSDTSEVIIHYDLKPANILFDEN---FVPKIADFG
|||.. ||||  ...|                   ..|| .|       ...|...||    ...       |||.|.|| |||||.|   . .||.|||
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNN------IIHRDIKPENILFDNNGKNYYIKIIDFG

LSKIADE---------------GKSIMQSTPGTGTVGYT----APETFTS-NNKVSLS--TDTWSLGIIYYEMMTN----DNELKRKIQTVDA-------
.||  ..                . .|...  .|| .|     ||| . . |.  | .   | ||||.| |||...    . . . . |.. .       
ISKKYQQNNNCDTNQQQKMQIWKQQMMWTF--CGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAY

--QTCEKIVNESLDDKKVKS-----KLSEKGQEFIK----ICLRKDPKDRPTIKALAEMDYI
  |  ..| .  .. .| .      ..|.....||.     .| |.|. |.|.. . .  ..
RKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 93904.m00234.AA STE 213-481 20 6.1e-40 138.74 In-house 1-359 (359) Show / Hide
Range on Protein: 213-481
Range on HMM: 1-359/359
Sequence Identity: 20% (77 aa)

IQLIEPIGRGGFAEVWKAWDYE---------------TAQIVAVKVIELPKN-----------VNLA--QFANHLKREIDIMTVTE--HKNVIKILRYFY
 ..|| ||.|.| .| || . .               | .|.|.|...| ..           ..    .  . ...||.||      |.|..| . ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

LA------DNTVAYVMEFAGGGDLNGILR---KVRLT------------ESEAHSIIKQVIDGLLALKSKPSDTSEVIIHYDLKPANILFDENFVPKIAD
        |...  .||. .|| |  |..   ..  .            ||.   |..|.. |||... .       ||| |.||||||.      |..|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-----IIHRDIKPANILL-----VKLCD

FGLSKIADE------------------GKS-IMQSTPGTGTVGYTAPETFTS-----NNKVSLSTDTWSLGIIYYEMMTNDNEL---KRK---IQTVDA-
||.... ..                  .|.  .  ||      . |||  .      ... . . | ||||.   || |   ..   .      .. .  
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP------WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNY

-------------QTCEKIVN--------------ESLDDKKVKSKLSEKGQEFIKICLRKDPKDRPTIKALAE--MDYI
             ... .. .              . .    ...|.|.. ..||. ||.|||..||| . | .     |
HMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGT-T----YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 93904.m00234.AA TKL 219-471 18 2.2e-36 127.17 In-house 1-356 (364) Show / Hide
Range on Protein: 219-471
Range on HMM: 1-356/364
Sequence Identity: 18% (69 aa)

IGRGGFAEVWKA-WDYET-------AQIVAVKVIELPKNVN-----------------------LAQFANHLKREIDIMTVTEHKNVIKILRYFYLADNT
||.|||.||.|. |  ..       .. ||||..    . .                       . .|  ....|| .|  . | |..... |    ...
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VAYVMEFAGGGDLNGILRKVRLTESEAHSIIKQVIDGLLALKS------KPSDTSEVIIHYDLKPANILFDENFV-------------
             . |||.. ||.|  .|       .  .......  |.  | |      .       ||| |||..||| |||.              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT----KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PKIADFGLSKIADEGKS-------IM----------QSTPGTGTVGYTAPETFTSNN---------------KVSLSTDTWSLGIIYYEMMTNDNELK-
 .||.|||||.  .. ..       .|          .. .  || .. ||| .  ..               . | ..| .| ||. .|..|     . 
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

RKIQTVD---------AQTCEKIVNESLDDK-------KVKSKLSEKGQEFIKICLRKDPKDRPT
 .  ...         .. |.|     ...           .   .   . .. |   ||..||.
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPS

Kinase 93904.m00234.AA TLK 214-415 35 2.1e-35 121.2 In-house 2-219 (285) Show / Hide
Range on Protein: 214-415
Range on HMM: 2-219/285
Sequence Identity: 35% (80 aa)

QLIEPIGRGGFAEVWKAWDYETAQIVAVKVIELPKNVNLAQFANHLK---REIDIMTVTEHKNVIKILRYFYLADNTVAYVMEFAGGGDLNGILRKVR-L
|| .  |.||| ||.||.| .    ||.|.  | ||      || .|   || .|    .| ...|   || .  |. . | |.  | ||   | . . .
QLLHLLGKGGFSEVYKAFDLHEFRYVACKIHQLNKNWKEEKKANYIKHACREYKIHKELDHCRIVKLYDYFEIDNNSFCTVLEYCEGNDLDFYLKQHKTM

TESEAHSIIKQVIDGLLALKSKPSDTSEVIIHYDLKPANILFDEN----FVPKIADFGLSKIADEGKSI----MQSTP-GTGTVGYTAPETFT-------
 | || .||.|..  |  | .. .     ||||||||.||.| .      . || ||||||| | ..      |  |  | ||  |  ||.|        
PEKEARCIIMQIVCCLKYLNEIKPP----IIHYDLKPQNIIFHKGNTCGEI-KITDFGLSKIMDDEQYRHDHGMELTSQGAGTYWYLPPECFVVGKCEEF

-SNNKVSLSTDTWSLGIIYYEMM
    |.|   | || |.|.|...
ENPPKISCKVDVWSVGVIFYQCL

Kinase 93904.m00234.AA CMGC 213-417 20 2.5e-35 112.86 In-house 1-331 (513) Show / Hide
Range on Protein: 213-417
Range on HMM: 1-331/513
Sequence Identity: 20% (69 aa)

IQLIEPIGRGGFAEVWKAWD--------------YETAQIVAVKVIELPKNVNLAQ-------FANHLKREIDIMTVTE-----------------HKNV
 . |..||.| ...|.|..|               || .|||.| | .|.. . |.       |     ||| |.                     |.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IKILRYFYLAD----------------NTVAYVMEFAGGGDLNGILRKVR----------LTESE------------AHSII------KQVIDGLL--AL
.|.. .||  .                | .  |.|. .  || ..... .          |.| .              ...      .|.. ||    .
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

KSKP-SDTSEVIIHYDLKPANILFDENFVP--------------------KIADFGLSKIADEG-------------------KSIMQSTPGTGTVGYTA
 |.  .     ||| ||||.|||...|                       ||.||||... ..                    |. .. |.   |  | |
HSHWGN-----IIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRA

PETFTSN---------NKVSLSTDTWSLGIIYYEMMTN
||   .          .. . . | ||.| | .||.|.
PEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTG

Kinase 93904.m00234.AA CAMKL 214-325 23 1.2e-25 78.73 In-house 2-140 (297) Show / Hide
Range on Protein: 214-325
Range on HMM: 2-140/297
Sequence Identity: 23% (33 aa)

QLIEPIGRGGFAEVWKAWD-YETAQIVAVKVIELPKNVNLAQFANH-----------LKREIDIMTVTE---HKNVIKILRYFYLADN-----TVAYVME
.... .|.|.|..|  |..   | . ||.|.|.  |  |  .  ..           ..||| ||       |.|.||..  ..  ..      .  |||
RIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVME

FAGGGD--LNGILRKV-----RLTESEAHSIIKQVIDGL
 ..||.  |   ..|      |..|.||. . .|.....
YCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAV

Kinase 93904.m00234.AA TyrKc 213-481 24 1.1e-17 63.22 SMART 1-280 (280) Show / Hide
Range on Protein: 213-481
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

IQLIEPIGRGGFAEVWKAWDYETAQIVAVKVIELPKNVNLAQFANHLKREIDIMTVT--EHKNVIKILRYFYLA------DNTVAYVMEFAGGGDLNGIL
|.|.. .|.| | ||.|.  .   . ||||..   .          . ||. ||.    .|.|..... .          .  .  |||.. .|||.  |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

RKVR--LTESEAHSIIKQVIDGLLALKSKPSDTSEVIIHYDLKPANILFDENFVPKIADFGLSKIADEG-------KSIMQST--PGT--GTVGYTAPET
|| |  |. .. .|.  |. .|   | ||       .|| ||   |.| .||.. ||.|||||.  ...       . .....   |     .  .|||.
RKHRPKLCMKDLLSFCWQIACGMEYLHSK------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

FTSNNKVSLSTDTWSLGIIYYEMMTNDNELKRK-IQ--TVDAQTCEKIVNESLDDKKVK------SKLSEKGQEFIKICLRKDPKDRPTIKALAEMDYI
.   .| .  .| || |.  .|..|.  .     ||    ...  |.. .    ..            ...  . .| | . ||.|||| ...   ...
I-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 93904.m00234.AA CAMKL 339-481 25 8e-16 46.83 In-house 148-297 (297) Show / Hide
Range on Protein: 339-481
Range on HMM: 148-297/297
Sequence Identity: 25% (40 aa)

IIHYDLKPANILFDENF--VPKIADFGLSKIADE--GKSIMQSTPGTGTVGYTAPETFTS--NNKVSLSTDTWSLGIIYYEMMT-----NDNELKRKIQT
|.| |.|| |||.|||   . ||.|||.| . ..   ..    .   |.  | ||| | .         .| ||.|.| | |..     .|  .. |   
IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN-KQGK

VDAQTCEKIVNESLDDKKVKSKLSEKGQEFIKICLRKDPKDRPTIKALAEMDYI
 .  . ......      . ...|   . .|.  | ..|..||||. . .    
DNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 93904.m00234.AA Pkinase_Tyr 213-416 27 1.7e-10 36.18 Pfam 1-209 (270) Show / Hide
Range on Protein: 213-416
Range on HMM: 1-209/270
Sequence Identity: 27% (61 aa)

IQLIEPIGRGGFAEVWKAWDY----ETAQIVAVKVIELPKNVNLAQ-FANHLKREIDIMTVT-EHKNVIKILRYFYLADNT--VAYVMEFAGGGDLNGIL
|.... .|.| | ||.|.  .    .| . ||||..  . .    | .   . ||. ||.    |.|... .   .  .    .  |||.. .|||   |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RKV-----RLTESEAHSIIKQVIDGLLALKSKPSDTSEVIIHYDLKPANILFDENFVPKIADFGLSKIADEGKSIM--QSTPGTGTVGYTAPETFTSNNK
||      .|| ..  ..  |. .|.  | ||.      .|| ||   |.| .||.| ||.||||..   . ..    ... |   .  .||| . ...|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN------CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECI-NYGK

VSLSTDTWSLGIIYYEMMT
 .  .| || |.  .|..|
FTTKSDVWSFGVLMWEIFT

Kinase 93904.m00234.AA CMGC 444-481 20 2.9e-05 12.23 In-house 466-513 (513) Show / Hide
Range on Protein: 444-481
Range on HMM: 466-513/513
Sequence Identity: 20% (10 aa)

KKVKS----------KLSEKGQEFIKICLRKDPKDRPTIKALAEMDYI
.|.||          ...... ...| .|. ||..|.|..   ...|.
EKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF

Kinase 93904.m00234.AA TLK 451-481 29 0.003364 7.19 In-house 255-285 (285) Show / Hide
Range on Protein: 451-481
Range on HMM: 255-285/285
Sequence Identity: 29% (9 aa)

SEKGQEFIKICLRKDPKDRPTIKALAEMDYI
|.  . ||. ||  .  ||  ...|..  |.
SNECKDFIRRCLQYRQEDRWDVQQLWNHPYM

Kinase 93904.m00234.AA Pkinase_Tyr 461-478 44 5.338159 0.62 Pfam 252-269 (270) Show / Hide
Range on Protein: 461-478
Range on HMM: 252-269/270
Sequence Identity: 44% (8 aa)

CLRKDPKDRPTIKALAEM
| ..||.|||| ... |.
CWHYDPEDRPTFSEIHEQ