Gene 86188.m00120 (T.vaginalis)

86188.m00120

Species: T.vaginalis
Alias: TvagK0191, 86188.m00120
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
86188.m00120.AA Protein None 199 None Fasta, JSON
86188.m00120.kin_dom Protein Kinase Domain None 185 None Fasta, JSON

Protein domain

Protein domains of 86188.m00120.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86188.m00120.AA CAMK 20-196 19 1.8e-56 180.1 In-house 1-327 (425) Show / Hide 
Range on Protein: 20-196
Range on HMM: 1-327/425
Sequence Identity: 19% (63 aa)

VIGEGGYGILYLVYHEQYK------------SYFAMKKIP---------------------------------EKRFNQAEIDCLKN-------IDHPNI
..|.|..|. .|..| . .              .|.| |.                                  ... . ||...|.       .|||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLYKYYFFNGF-------------------VYLLM---EYCPVD------LSMILQKQSE--------------LDEEILRKYVHDILLAIKACHDRCI
..|| .|  . .                   .|. |   |||.        ...| .. ..              ..|.  |.|.. |. |.. ||.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHSDIKPSNFLIDKY-----------------GRIKVCDFGFSDVYE-------------------------NCSCQMYCGTLLFIA-PEVLKK------
.| |.|| | |.|.                  . ||..||||. ...                         .  .. .|||. ..| ||||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QEYNPMKADIWALGVTLYYM
       ..| . |.|.|..|| || |
QNATDEEKPYYGPKCDMWSCGVILYIM
Kinase 86188.m00120.AA CAMKL 16-198 29 5.7e-51 160.81 In-house 2-231 (297) Show / Hide 
Range on Protein: 16-198
Range on HMM: 2-231/297
Sequence Identity: 29% (67 aa)

TFDKVIGEGGYGILYLVYHEQY-KSYFAMKKIP-----EKRFNQA---------------EIDCLKNID---HPNIVSLYKYYFFNGF------VYLLME
.. |..|.|..|   |  |... .   |.| |      .. ....               || ..| ..   ||||..||  .    .      .|| ||
RIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVME

YCP---VDLSMILQKQSE----LDEEILRKYVHDILLAIKACHDRCIAHSDIKPSNFLIDKYG--RIKVCDFGFSDVYE------NCSCQMYCGTLLFIA
||.   .||   ..|. .    ..|.  |.|   |. |.. ||...|.| |||| | |.|. |   ||..|||||  |.      .  . . ||.. . |
YCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMA

PEVLKK--QEYNPMKADIWALGVTLYYMAT
||....  ..|.  |.|||..||.|| | .
PEIFQGNNKPYDGPKVDIWSCGVILYAMVC
Pkinase 86188.m00120.AA Pkinase 15-199 30 5.5e-50 177.17 Pfam 1-208 (293) Show / Hide 
Range on Protein: 15-199
Range on HMM: 1-208/293
Sequence Identity: 30% (64 aa)

ITFDKVIGEGGYGILYLVYHEQYKSYFAMKKIPEKRFNQ---------AEIDCLKNIDHPNIVSLYKYYFFNGFVYLLMEYCPV-----DLSMILQ--KQ
... ..||.|..|  |. .|  .   .|.|.|. .. .          .||  .|...||||| || ..  .. .|. ||||.      ||. ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SEL--DEEILRKYVHDILLAIKACHDRCIAHSDIKPSNFLIDKYGRI----KVCDFGFSD---VYENCSCQMYCGTLLFIAPEVLKKQEYNPMKADIWAL
  .  .|. ...|.  || ... ||.. | | |.||.|.|||. | |    |.||||..       |  .. .|||. ..||||.....| . |.|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTLYYMATK
|..||.|...
GCILYEMLCG
Kinase 86188.m00120.AA AGC 15-198 22 3.1e-49 124.32 In-house 1-300 (395) Show / Hide 
Range on Protein: 15-198
Range on HMM: 1-300/395
Sequence Identity: 22% (69 aa)

ITFDKVIGEGGYGILYLVYHE------QYKSYFAMKKIP-----------EKRFNQAE------------IDCLKNID----------HPNIVS-LYKYY
  | ||||.|..|  ||| .       . . |.|||..            . . ...|             . |....          ||.||. |.  .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

FFNGF--VYLLMEYCP----------V-DLSMILQ---KQSELDEEILRKYVHD-------ILLAIKACHD-RCIAHSD-IKPSNFLIDKYGRIKVCDFG
  .    .|..|||.|            .| ..||   |.  .|||  | |          |.||.   |. . | | | .|| | |.|. | || .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FSDVYEN----------------------------------------------------CSCQMYCG--TLLFIAPEVLKKQEYNPMKADIWA--LGVTL
.. .  |                                                      ..  ||  |  ..|||.|    |..  .|.|.  ||. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

YYMAT
| | |
YEMLT
Kinase 86188.m00120.AA ULK 15-196 26 9.4e-40 136.47 In-house 1-249 (329) Show / Hide 
Range on Protein: 15-196
Range on HMM: 1-249/329
Sequence Identity: 26% (65 aa)

ITFDKVIGEGGYGILYLVYHEQYK----SYFAMKKIP---EKRFN------------QAEIDCLKNID--------HPNIVSLYKYYFFNGF--VYLLME
.  ....|.| .|  |  .... |     ..| |.|.   ....|            . ||. .| ..        ||||| ||...    .  .|. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPV-DLSMILQKQSE----------LDEEILRKYVHDILLAIKACHDRCIAHSDIKPSNFLIDKY------------GRIKVCDFGFSDV--YE-----
||.  ||. ...|. .          | |.. ... ..|| . |. |.. | | ||||.| ||..             |..|..||||. .  ..     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-NCSCQ---MYCGTLLFIAPEVLK----KQEYNPMKADIWALGVTLYYM
 ...|     .||| |. ||..|.    ...|.  |.||| ||. .|.|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEM
Kinase 86188.m00120.AA Ciliate-E2-Unclassified 15-198 24 2.7e-39 133.95 In-house 1-265 (352) Show / Hide 
Range on Protein: 15-198
Range on HMM: 1-265/352
Sequence Identity: 24% (66 aa)

ITFDKVIGEGGYGILYLVYHEQYKSYFAMKKIP-------------EKRFNQAEIDCLKN----------------IDHPNIVSLYKYYFF--NGFVYLL
 .. |.||.||.|. |...|.. | |.||| .              . .... ..   ..                ..||... ....| |     .|. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCP-VDLSMILQKQSE-----------------LDEEILR-----KYVHDILLAIKACHDRC-IAHSDIKPSNFLIDKYG---RIKVCDFGFSD----
||||.  ||. ...|..                  ..|.  .     .|   ||.... .|    | | ||||.| |.|. |   .||..|||.|     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-------------VYENCSCQMYCGTLLFI----APEVLKKQEYNPM---KADIWALGVTLYYMAT
             .. .. ..  |||. ..    |||||..|.|. .   |.|||.||| ||.| .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLF
S_TKc 86188.m00120.AA S_TKc 15-199 27 3.8e-39 137.28 SMART 1-220 (231) Show / Hide 
Range on Protein: 15-199
Range on HMM: 1-220/231
Sequence Identity: 27% (65 aa)

ITFDKVIGEGGYGILYLVYHEQYKSYFAMKKIPEKRFNQAEIDCLKNIDHPNIVSLYKYYFFNGFVYLLMEYCPV---DLSMILQKQSE------LDEEI
 .. ..||.|..|  |...|   . ..|.|.|.  .  . ||..||. .||||| || ..   ...|. ||||.    ||  ...|.        ..|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LRKYVHDILLAIKACHDRCIAHSDIKPSNFLIDKYGRIKVCDFGFSDVYENCSCQMYCGTLLFIAPEVLKKQEYNPMKADIWALGVTLYYMAT-------
 |.|.. |..|.. ||.. | | |.||.| |.|.  .||.||||.. ..       .|||. ..|||||    |.. |.|.|..|..|| |..       
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFPQ

----------------------------------K
                                  .
MQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ
Kinase 86188.m00120.AA ULK 15-196 26 9.2e-39 135.1 In-house 1-245 (324) Show / Hide 
Range on Protein: 15-196
Range on HMM: 1-245/324
Sequence Identity: 26% (64 aa)

ITFDKVIGEGGYG-ILYLVYHEQY---KSYFAMKKIP---EKRFNQA------------EIDCLKNID---HPN--IVSLYKYYFFN--GFVYLLMEYCP
.  ....|.| .|   |  ....    . |.| |.|.    . ...             ||  .| ..   |||  || ||...      ..|. ||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

V-DLSMILQKQSE---------LDEEILRKYVHDILLAIKACHDRCIAHSDIKPSNFLIDKY------------GRIKVCDFGFSDVYEN-----CSCQM
  ||. ...|. .         | |.. ... ..|. . |. |.. | | ||||.| || .             |..|..||||. . .|     . || 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YC------GTLLFIAPEVLK----KQEYNPMKADIWALGVTLYYM
..      || |. ||..|.    ...|.  |.||| ||. .|.|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEM
Kinase 86188.m00120.AA MARK 16-198 34 2.8e-37 119.54 In-house 2-201 (262) Show / Hide 
Range on Protein: 16-198
Range on HMM: 2-201/262
Sequence Identity: 34% (68 aa)

TFDKVIGEGGYGILYLVYHEQYKSYFAMKKIP-------EK-RFNQAEIDCLKNIDHPNIVSLYKYYF--FNGF-VYLLMEYCP-VDLSMILQKQ--SEL
 . |.||.|.|.  .|. |  ..  .| | ..       .. .  . ||. .| .|||||..|...     ..  .|| |||..  .|   ....    |
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL

DEEILRKYVHDILLAIKACHDRCIAHSDIKPSNFLIDKYG--RIKVCDFGFSDVY-ENCSCQMYCGTLLFIAPEVLKKQEYNPMKADIWALGVTLYYMAT
 ||  |.. . |. |.. ||.. |.| |||| | |||. |   || .|||||    ...   . |||. . |||...|..|.  |.|||.||| ||.| .
HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVC
Kinase 86188.m00120.AA Ciliate-E2 15-196 21 1.4e-36 123.07 In-house 1-289 (365) Show / Hide 
Range on Protein: 15-196
Range on HMM: 1-289/365
Sequence Identity: 21% (64 aa)

ITFDKVIGEGGYGILYLV--YHEQYKS----------------YFAMKKIPEKRFNQAEIDCLKN-----------------------IDHPNIVSLYKY
. | |.||.|..|. |..  . .|...                ....|..  |.... .|  .|.                       ..||||. .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YF--FNGFVYLLMEYCPV-DLSMILQKQ-----------SELDEEILRKYVHDILL---------------AIKACHDRC-IAHSDIKPSNFLIDKYGRI
.    .  .|| ||||   ||  .....             ..|.  ...   ||                |.. .| .  | | ||||.| |.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KVCDFGFSDVYENCSC------------------------------QMY---CGTLLFIAPEVLKKQEY--------NPMKADIWALGVTLYYM
|..|||.|  | ....                              .|.   |||. . |||.|....|           |.|||.|||.||.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM
Kinase 86188.m00120.AA STE 15-198 22 5.3e-35 121.08 In-house 1-263 (359) Show / Hide 
Range on Protein: 15-198
Range on HMM: 1-263/359
Sequence Identity: 22% (60 aa)

ITFDKVIGEGGYGILYLVYHE------QYKSY---------FAMKKIP----------------------EKRFNQAEIDCLKNID--HPNIVSLYKYYF
 .. ..||.|..|  |. ..       . .           .|.|...                      |.   . ||. .|. .  |||||  | .||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FNG-------FVYLLMEYCPV-DLSMILQ----KQSELD----------EEILRKYVHDILLA-IKACHDRCIAHSDIKPSNFLIDKYGRIKVCDFGFSD
 .|        ... |||..   |. |..    .. .|.          |.........|| .  .  |.  | | ||||.| |.     .| ||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

VYEN------------------CSCQMYCGTLLFIAPEVLKK------QEYNPMKADIWALGVTLYYMAT
  ..                    ..  .||  . ||||...      ..|.  |.||| || |.  |||
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMAT
Kinase 86188.m00120.AA CMGC 15-198 19 7.2e-35 111.34 In-house 1-330 (513) Show / Hide 
Range on Protein: 15-198
Range on HMM: 1-330/513
Sequence Identity: 19% (64 aa)

ITFDKVIGEGGYGILYLVYH--------------EQYKSYFAMKKIP---EKRFNQ-------------AEIDCLKNI-----------------DHPNI
 . .|.|||| ||. |  ..               ... . |.|||    ...  .              || .||..                 .|.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VSLYKYYFFNG-----------------FVYLLMEYCPVDLSMILQKQS---------ELDEEI------------LRKYV------HDILLAIK--ACH
|.|| .. ...                  .|| .||.. ||  ......         .|.|               ....      . || ..|   ||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

DRC--IAHSDIKPSNFLID--------------------KYGRIKVCDFGFSDVYENCS-----------------------CQMYCGTLLFIAPEVLKK
 ..  | | |.||.| ||.                    | ||.|.||||..  |.. |                          |  |.   |||.|  
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

QEYNP---------MKADIWALGVTLYYMAT
 ..            . |.|..|  .. | |
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYT
Kinase 86188.m00120.AA TyrKc 15-196 17 2.3e-07 -103.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-196
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

ITFDKVIGEGGYGILYL-VYHEQYKSYF-AMKKIPEKRFNQA---EIDCLKNI--DHPNIVSLYKYYFFN-------GFVYLLMEYCPV-DLSMILQKQS
||..|..||| .|. |. ..      .  | |.. |    ..   |.  ....  .||||| || .           . ....|||.|  ||   |.|  
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

E-LDEEILRKYVHDILLAIKACHDRCIAHSDIKPSNFLIDKYGRIKVCDFGFSDVYENC-----SCQMY------CGTLLF----IAPEVLKKQEYNPMK
. |  . | .. ..|       |.... | |.   | |... ...|..||| |   ..      | ..|      .|  ..     |||.... .... |
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-K

ADIWALGVTLY-------------------------------------Y-------------------------------------M
 |.|. ||...                                     .                                     .
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF