Gene TVAG_308340 (T.vaginalis)
TVAG_308340
Species: T.vaginalis
Alias: TVAG_308340, TvagK1064
External Links:
Annotation:
Group:
TKL
Family:
TKL-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| TVAG_308340.AA | Protein | None | 793 | None | Fasta, JSON |
| TVAG_308340.kin_dom | Protein Kinase Domain | None | 178 | None | Fasta, JSON |
Protein domains of TVAG_308340.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | TVAG_308340.AA | CAMK-Unique | 102-150 | 22 | 6.9e-07 | 18.56 | In-house | 121-190 (363) | Show / Hide |
Range on Protein: 102-150 Range on HMM: 121-190/363 Sequence Identity: 22% (16 aa) TLLDILQKG-------------------EVKFTP--EQKRSIAVSTASAIRFLHNSKIVHNNLYLDNVLV .|.|..||. . .|. . ..| ...||. ..|. .||| .| |.|..| DLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMV |
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| Kinase | TVAG_308340.AA | TKL | 102-155 | 24 | 9.1e-07 | 20.4 | In-house | 124-178 (364) | Show / Hide |
Range on Protein: 102-155 Range on HMM: 124-178/364 Sequence Identity: 24% (15 aa) TLLDILQKGEVKFTPEQKRSIAVSTASAIRFLHNSK--------IVHNNLYLDNVLVTPEGT .||..|. ..|. ..| ..|... .||... |.| .| .|.|| .| SLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWT |
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| Kinase | TVAG_308340.AA | Ciliate-E2-Unclassified | 102-154 | 16 | 1e-06 | 19.17 | In-house | 107-181 (352) | Show / Hide |
Range on Protein: 102-154 Range on HMM: 107-181/352 Sequence Identity: 16% (12 aa) TLLDILQKGEV----------------KFTPEQKR-----SIAVSTASAIRFLHNSK-IVHNNLYLDNVLVTPEG .|.....| . .|| .| . .. ... .|| .. |.| .. ..|.|.. .| DLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNG |
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| Kinase | TVAG_308340.AA | NKF4 | 127-151 | 32 | 6.5e-05 | 11.16 | In-house | 146-170 (336) | Show / Hide |
Range on Protein: 127-151 Range on HMM: 146-170/336 Sequence Identity: 32% (8 aa) ASAIRFLHNSKIVHNNLYLDNVLVT |.|. .|| .|.|. | .|.... AQAMAHLHKNHIIHRDLKPYNIIIV |
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| Kinase | TVAG_308340.AA | C8 | 103-156 | 24 | 0.000113 | 12.27 | In-house | 109-162 (226) | Show / Hide |
Range on Protein: 103-156 Range on HMM: 109-162/226 Sequence Identity: 24% (13 aa) LLDILQKGEVKFTPEQKRSIAVSTASAIRFLHNSKIVHNNLYLDNVLVTPEGTS | | ... ...|. |.| ||. . ..| .|.| . ..| || ..... LYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNY |
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| Kinase | TVAG_308340.AA | Ciliate-C4 | 127-150 | 37 | 0.000155 | 10.07 | In-house | 150-173 (361) | Show / Hide |
Range on Protein: 127-150 Range on HMM: 150-173/361 Sequence Identity: 37% (9 aa) ASAIRFLHNSKIVHNNLYLDNVLV ..|. .||. |.|| .. ..| || CHALWHLHQNKWVHCDIKPENILV |
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| Kinase | TVAG_308340.AA | SLK | 111-154 | 29 | 0.000169 | 10.96 | In-house | 91-134 (259) | Show / Hide |
Range on Protein: 111-154 Range on HMM: 91-134/259 Sequence Identity: 29% (13 aa) EVKFTPEQKRSIAVSTASAIRFLHNSKIVHNNLYLDNVLVTPEG | | .| . .. . |...||. |..| .| |.|.| .| EHPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDG |
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| Kinase | TVAG_308340.AA | UTK | 111-151 | 29 | 0.000172 | 11.28 | In-house | 112-152 (296) | Show / Hide |
Range on Protein: 111-151 Range on HMM: 112-152/296 Sequence Identity: 29% (12 aa) EVKFTPEQKRSIAVSTASAIRFLHNSKIVHNNLYLDNVLVT .. .| .|. . |. |.. .||. ..||..| |.||. PHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVH |
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| Kinase | TVAG_308340.AA | Ciliate-C8 | 102-198 | 17 | 0.000282 | 11.62 | In-house | 104-238 (238) | Show / Hide |
Range on Protein: 102-198
Range on HMM: 104-238/238
Sequence Identity: 17% (23 aa)
TLLDILQKGEVKFTPEQKRSIAVSTASAIRFLHNSKIVHNNLYLDNVLVTPEGTS--------------FVSGYGIPYSQN------TVTTIRP-EFW--
...| ..| .. .. ..| ||. . .|| |.| ..| || .. .. | .|.... ..|. . |.
QYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFC
-----NPPEQAPS---NEGDIFD-------LGLIF
.||. .. ||| .||..
GNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
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| S_TKc | TVAG_308340.AA | S_TKc | 25-247 | 11 | 0.0004 | -116.43 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 25-247
Range on HMM: 1-231/231
Sequence Identity: 11% (30 aa)
INEEKQ-------CVFPAKNSESGERYFVTFIKDGLPENTKIWAYLTSLMNIDFISLLPIVGFSHPETSNFTYPAIFQKNQGF--PTLLDILQKGEVK--
.. .|. ... ..|... . || .|. . |.. . . . .. . .. .. . .|.|...| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL
---FTPEQKRSIAVSTASAIRFLHNSKIVHNNLYLDNVLVTPEGTSFVSGYGIPYSQNTVTTIRPEFWNPPEQAPSNEG---DIFDLGLIFKAIFTEKVP
|.. . |... ...|. ..|. .|.| | .|.|.. . .. |. | . .. .|| . . |. .| |. .. . |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPP
TDISIPEDA------PEALKAILEGCFTEIKGNRITEDSLIT-------ALFS
. ... .. .| ....|.. .|.| . . .
FP---QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | TVAG_308340.AA | Eta | 113-154 | 35 | 0.00065 | 8.98 | In-house | 96-137 (261) | Show / Hide |
Range on Protein: 113-154 Range on HMM: 96-137/261 Sequence Identity: 35% (15 aa) KFTPEQKRSIAVSTASAIRFLHNSKIVHNNLYLDNVLVTPEG || | | .|. |||. .. | |||.|. || KFDEPRARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEG |
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| Sel1 | TVAG_308340.AA | Sel1 | 296-331 | 15 | 9e-06 | 22.26 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 296-331 Range on HMM: 1-43/43 Sequence Identity: 15% (7 aa) AAAMNKVG--LQFEKGI-D--CDR-D-DAQ-SLNFFNMAADKGS . |....| . ...|. . . . | ... .. .. .||..|. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 332-369 | 27 | 0.080784 | 9.18 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 332-369 Range on HMM: 1-43/43 Sequence Identity: 27% (12 aa) IEALCNLG--RIYFEGNNRF-APQ-S-IPN-AISFYDCAGAHGE | .||| ..|..| . || . |. .| | ..| P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 405-417 | 38 | 0.168521 | 8.12 | Pfam | 31-43 (43) | Show / Hide |
Range on Protein: 405-417 Range on HMM: 31-43/43 Sequence Identity: 38% (5 aa) AIQFYERAASLGN |...|..|| .|. AFYWYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 559-591 | 24 | 7.1e-08 | 29.28 | Pfam | 1-40 (43) | Show / Hide |
Range on Protein: 559-591 Range on HMM: 1-40/43 Sequence Identity: 24% (10 aa) ALALNDLG--ECYLYGN--G-CQQ-N-ITE-ARRYFEQAAN . | . || ..|..| | . | . . . |......||. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAE |
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| Sel1 | TVAG_308340.AA | Sel1 | 454-486 | 22 | 0.000164 | 18.12 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 454-486 Range on HMM: 1-43/43 Sequence Identity: 22% (10 aa) APAQNEYA--R---YLE--K-ILK-D-EDD-ALRFYMLAADQGH . ||.... . . . . . | . |...| .||.||| P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 523-558 | 18 | 0.000319 | 17.16 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 523-558 Range on HMM: 1-43/43 Sequence Identity: 18% (8 aa) SLAMLKLG--QLLLSGK--L-VER-N-AEE-GFQLIKSSVELKN . |...|| .... |. |.. . |. .|.. . . |. . P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 487-522 | 18 | 0.003952 | 13.53 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 487-522 Range on HMM: 1-43/43 Sequence Identity: 18% (8 aa) ELALFNAGRILMKKKGD----TDA---ISR-GIEYMRLAAEKNN | .| |...| .|. . . . .......|||... P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 444-453 | 40 | 18.570327 | 1.34 | Pfam | 34-43 (43) | Show / Hide |
Range on Protein: 444-453 Range on HMM: 34-43/43 Sequence Identity: 40% (4 aa) FLRRAAEAGS ....|||.|. WYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 703-738 | 40 | 4.5e-11 | 39.91 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 703-738 Range on HMM: 1-43/43 Sequence Identity: 40% (18 aa) TNAMFNLG--AMYENGA--G-VPQ-S-QAD-ANKYYFMAAEQGN |..||| ||..| | ||| . | ..| .|||||. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 667-702 | 34 | 1.2e-10 | 38.49 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 667-702 Range on HMM: 1-43/43 Sequence Identity: 34% (15 aa) SYAYSNLG--RMYQNGK--G-VTQ-D-SKL-AVKMFRRAIELGN . |. ||| .||..|. | |.| | .. |.. ...| |.|. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 629-666 | 27 | 0.00031 | 17.2 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 629-666 Range on HMM: 1-43/43 Sequence Identity: 27% (12 aa) PIGMICCG--QLLESGF-GG-AEEPR-YAQ-ASSYYQRAAALGN | .. | .... | || ... |.. | .||.||..|. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_308340.AA | Sel1 | 595-628 | 26 | 0.008419 | 12.44 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 595-628 Range on HMM: 1-43/43 Sequence Identity: 26% (12 aa) PRGCTNYGHMLI--QEGP----M---R-YKE-AFAVYRLAAEMND | .. |.| |. ..| |.. ||. |..|||... P-AQYNLG-MYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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