Gene 97166.m00054 (T.vaginalis)

97166.m00054

Species: T.vaginalis
Alias: 97166.m00054, TvagK0258
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
97166.m00054.AA Protein None 328 None Fasta, JSON
97166.m00054.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of 97166.m00054.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 97166.m00054.AA S_TKc 16-263 25 2.4e-70 240.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 16-263
Range on HMM: 1-231/231
Sequence Identity: 25% (68 aa)

LVFNQVIAHGSYGIVFLVYSIQYQSYFAVKQVPEKMFHEQEVRCLMELDDIRIVYLYKYFKIDDCYYFVMEYCPN---DLEHFLNTKKM------ISEEV
  . ..| .|..| |.... .  . ..|.|...     ..|...|.. .   || || .|   |..|.|||||..   || ...  ..       ..| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

QRNIMKEVLLSVKVCHDNHIAHRDIKPSNFLIDKYGRIRLSDFGLSTFQTYDEKCSEYVGTHFFMAPEIYAHKKDGSSYNPILSDIWAIGVTLYFIATRR
 | .|..... .. ||...| |||.||.| |.|.  .| ..||||...       . ..|| ..||||.        .|..  .|.|..|..||  ....
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCGY

FPFQSYDFNTLQEQIMSAQYDEKLIPDLRLRFIISNCLQVDPLRRPSISEILL-------MPYF
 ||.  . ... ..|.          .  .. .|..|||.|| .||.. |.|        .|.|
PPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 97166.m00054.AA CAMK 21-263 16 1.9e-59 189.89 In-house 1-425 (425) Show / Hide 
Range on Protein: 21-263
Range on HMM: 1-425/425
Sequence Identity: 16% (71 aa)

VIAHGSYGIVFLVYSIQYQ------------SYFAVKQVP---------------------------------EKMFHEQEVRCLME-------LDDIRI
.. .||.|.|.|.. .. .              .|.| ..                                  . . ..|.....        ||   |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VYLYKYFK------------IDDC--------YYFVM---EYCPN-----DLEHFLNTK---------------KMISEEVQRNIMKEVLLSVKVCHDNH
. || ..               ..        .|.||   |||..     ||  ..  .               . ..|.  | ... ..  |. ||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHRDIKPSNFLIDKY-----------------GRIRLSDFGLSTFQTY------------------------DEKCSEYVGTHFFMA-PEIYAHKK---
|.|||.|| | |.|.                  . | ..|||.... .                         ..|.....||  .|| ||.   |.   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

------DGSSYNPILSDIWAIGVTLYFIATRRFPFQSY-------------DFNTLQEQIMSAQY--DEKLIPDLR----------------------LR
      ..  | .  .|.|..|| ||.  . ..||..              . . | |.||...|  ... ....                        .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

FIISNCLQVDPLRRPSISEILLMPYF
  |...||||| .|..|...|  | .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 97166.m00054.AA Pkinase 16-263 25 5.4e-55 193.81 Pfam 1-293 (293) Show / Hide 
Range on Protein: 16-263
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

LVFNQVIAHGSYGIVFLVYSIQYQSYFAVKQVPEKMFHE---------QEVRCLMELDDIRIVYLYKYFKIDDCYYFVMEYCPN-----DLEHFLN--TK
... ..|  ||.| |.. . . ..  .|||... .  ..         .|.. . .|.   || || .|  .| .|.|||||..     || ...    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KMI--SEEVQRNIMKEVLLSVKVCHDNHIAHRDIKPSNFLIDKYGRI----RLSDFGLSTF--QTYDEKCSEYVGTHFFMAPEIYAHKKDGSSYNPILSD
. .  ||.. ...|...|  .. ||.. | |||.||.|.|||. | |    ...||||. .     .. .. ..|| ..||||.      |..| .  .|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GGQYYGPKVD

IWAIGVTLYFIATRRFPFQSY------DFNTLQEQIMSAQYDEKLIPD---------------------LRLRFIISNCLQVDPLRRPSISEILLMPYF
.|..|..||  ...|.||..       | . . ..||......    .                       .. .|..||..|| .||.. .||  |.|
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 97166.m00054.AA Ciliate-E2 16-263 20 1.1e-53 182.7 In-house 1-365 (365) Show / Hide 
Range on Protein: 16-263
Range on HMM: 1-365/365
Sequence Identity: 20% (78 aa)

LVFNQVIAHGSYGIVFLV--YSIQYQS----------------YFAVKQVPEKMFHEQEVRCLMELDDIR-----------------------IVYLYKY
  |...|  |..|.|...  .. |.|.                ....|..  |........ ..  ..|                        |. .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FK--IDDCYYFVMEYCPN-DLEHFLN--TKKM---------ISEEVQRNIMKEVLL---------------SVKVCHDNH-IAHRDIKPSNFLIDKYGRI
|.   |...|.|||||   ||.....   ||          ..|.  ..|||..|                 .. .| .. | ||||||.| |.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLSDFGLSTFQTYD----------EKCSEYV-----------------------GTHFFMAPEIYAHKKDG----SSYNPILSDIWAIGVTLYFIATRRF
 ..|||||.... |          ... .                         ||  .|||||.  ||..    . .    .|||..||.||.  . ..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFQSYDFNTLQEQIMSAQYD------------------EKLIPDLRLRFIISN----CLQVDPLRRPS-ISEILLMPYF
||        |.||.  ..|                  ...  ..    .|..    .||.||  |.. ...||  |.|
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 97166.m00054.AA CAMKL 16-263 25 6.3e-53 167.16 In-house 1-297 (297) Show / Hide 
Range on Protein: 16-263
Range on HMM: 1-297/297
Sequence Identity: 25% (76 aa)

LVFNQVIAHGSYGIVFLVYSIQY-QSYFAVKQVP-EKMFH-------------------EQEVRCLMELDDIR----IVYLYKYFKIDDC------YYFV
  . ... .||.| | |   |.. .   |.| .  .|.                     ..|..... |. |.    |. ||  .  ...      .| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYCPND---LEHFLNTK----KMISEEVQRNIMKEVLLSVKVCHDNHIAHRDIKPSNFLIDKYG--RIRLSDFGLSTFQT-Y----DEKCSEYVGTHFF
||||..    | ...  .    . ..|.  | . . ..  |. ||...|.|||||| | |.|. |   | ..|||.|.... .    ..|...  |.  .
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

MAPEIYAH-KKDGSSYNPILSDIWAIGVTLYFIATRRFPFQSY--------DFNTLQEQIMSAQYDEK--LIPDLRLRFIISNCLQVDPLRRPSISEILL
|||||..  .|   .|.    |||..||.||.. . ..||           .. .| ..||.  | .   . .. ..| .|.  |||.| .||.| .|. 
MAPEIFQGNNK---PYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

MPYF
 | .
HPWM
Kinase 97166.m00054.AA AGC 16-263 19 4.4e-50 126.57 In-house 1-395 (395) Show / Hide 
Range on Protein: 16-263
Range on HMM: 1-395/395
Sequence Identity: 19% (80 aa)

LVFNQVIAHGSYGIVFLVYSI------QYQSYFAVKQVPEKM---FHE--QEVRCLME---------------LDDIR-------------IVY-LYKYF
  |  ||  ||.| |.||         . . |.|.| .  |      .  .. . . |               |  ..             ||  |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KIDDC--YYFVMEYCP---------NDLEHFLNTKK-----MISEEVQRNIMKE-------VLLSVKVCHD-NHIAHRD-IKPSNFLIDKYGRIRLSDFG
. .|    ||||||.|          ..| ||  ..       .||. | .. |       ..| .   |. ..| ||| .|| | |.|. | |.|.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSTFQTYDE---------------------------------------------------KCSEYVG--THFFMAPEIYAHKKDGSSYNPILSDIWA--I
|..    |.                                                   ...  .|  |. .|||||         |..   |.|.   
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------YGK-ACDWWSFGL

GVTLYFIATRRFPFQS----------YDFNTLQEQIMSAQ---YDEKLIP-------------DLRLRFIISNCLQVDPLRRPS----------ISEILL
|. .|   | . ||..          .. . . ..||. .    ..  .|             .  .. .|. .|..|| .|.           ..||  
GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN

MPYF
 |.|
HPWF
Kinase 97166.m00054.AA Ciliate-E2-Unclassified 17-263 19 1.6e-46 159.43 In-house 2-352 (352) Show / Hide 
Range on Protein: 17-263
Range on HMM: 2-352/352
Sequence Identity: 19% (69 aa)

VFNQVIAHGSYGIVFLVYSIQYQSYF------------AVKQVPEK---MFHEQEVRCLMELDDIR-----------------IVYLYKYFKIDDCYYFV
 ....| .|..|.|.... .. . ..            ..||. .|   |. ..|. .... .. |                 ||... .|. ... |.|
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYC------------------PNDLEHFLNTKKMISEEVQR-----NIMKEVLLSVKVCHDNH-IAHRDIKPSNFLIDKYG---RIRLSDFGLSTFQTY
||||                   ||| | ....|...|.  .     ......|.  . .| .. | ||||||.| |.|. |   .|...|||.| .. .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

D----------------EKCSEYVGTHFFM----APEIYAHKKDGSSYNPILSDIWAIGVTLYFIATRRFPFQSYDFNT----------------LQEQI
.                ....  .||  .|    |||..  .. . |   . .|||. || ||.. . ..||.... .                 |...|
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

MSAQYDEKLIPD----LRLR--------FIISNCLQVDPLRRPSISEILLMPYF
.  ... .  |      ..          ... .|...|  |.....||  |.|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 97166.m00054.AA ULK 16-263 22 1.4e-45 157.78 In-house 1-324 (324) Show / Hide 
Range on Protein: 16-263
Range on HMM: 1-324/324
Sequence Identity: 22% (74 aa)

LVFNQVIAHGSYG-IVFLVYSIQY---QSYFAVKQVP---EKMF-HE-----------QEVRCLMELD---DIR--IVYLYKYFKIDDC--YYFVMEYCP
 . |... .||.|  |.  . ..    . |.|.|...    ... .|           .|.. . .|.        || ||..|. ...  .|..||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

N-DLEHFLNTK---------KMISEEVQRNIMKEVLLSVKVCHDNHIAHRDIKPSNFLIDKY------------GRIRLSDFGLSTF-QTYD---EKCSE
  |||......         | .||.  ....|  .   |  |.. | ||||||.| || .             |.. ..|||.. . . ..    .| .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YV------GTHFFMAPEIYAHKKDGSSYNPILSDIWAIGVTLYFIATRRFPFQSYDFNTLQEQ--------------IMSAQYDEKL-----IPDLRLRF
.|      ||  .|||.|   .  .  |. . .||| .|. .| . . . ||.|. ||.....              |   . . ..     .    .. 
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IISNCLQVDPLRRPSISEILLMPYF
.|. .||.|.  | |. ||. .| |
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 97166.m00054.AA ULK 16-263 23 8e-45 154.41 In-house 1-329 (329) Show / Hide 
Range on Protein: 16-263
Range on HMM: 1-329/329
Sequence Identity: 23% (76 aa)

LVFNQVIAHGSYGIVFLVYSIQY----QSYFAVKQVP----EKMFHE-----------QEVRCLMELD----DIR----IVYLYKYFKID--DCYYFVME
 . |... .||.| |.  . ..     . ..|.|...     .  .|           .|.. . .|.     .     || ||..|. .  ...|..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPN-DLEHFLNTK----------KMISEEVQRNIMKEVLLSVKVCHDNHIAHRDIKPSNFLIDKY------------GRIRLSDFGLSTFQTYD--EKC
||.  |||......          | .||.  ....|  |   |  |.. | ||||||.| ||..             |.. ..|||.. . ..|  |. 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

--SEYV------GTHFFMAPEIYAHKKDGSSYNPILSDIWAIGVTLYFIATRRFPFQSYDFNTLQ-EQIMSAQYDEKLIP----DLRLRFI---------
    .|      ||  .|||.|   .  .  |.   .||| .|. .| . . . ||... ||...  .|..   ... .|    .  |.|          
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

------ISNCLQVDPLRRPSISEILLMPYF
      |. .||.|.  | |. |.. .| |
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 97166.m00054.AA STE 16-263 19 3.6e-38 132.39 In-house 1-359 (359) Show / Hide 
Range on Protein: 16-263
Range on HMM: 1-359/359
Sequence Identity: 19% (70 aa)

LVFNQVIAHGSYGIVFLVYSIQ---------------YQSYFAVKQVP---------------------EKM-FHEQEVRCLMELD--DIRIVYLYKYFK
. . ..| .|..| |.. . .                 . ..|.||..                     |.|   ..|.. .....     ||  | .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ID-------DCYYFVMEYCP-NDLEHFLNTKKMIS--------------EEVQRNIMKEVLLS-VKVCHDNHIAHRDIKPSNFLIDKYGRIRLSDFGLST
 .       |  . .|||..   |. ....|...               |.. . | ...|    .  |..|| ||||||.| |.     . |.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FQTY-----------------DEKCSEYVGTHFFMAPEIYAHKKDG--SSYNPILSDIWAIGVTLYFIATRRFPFQSYDFNTLQEQIMSAQ---------
  |                  ..|.   |||  .||||.    . |  . |. . .||| .| |.   || . |.  .       .|.  .         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----YDEKLIPD----------------------LRLRFIISNCLQVDPLRRPSISEILL--MPYF
     .   .||                        ..  |..||| ||  ||. |. |    | .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 97166.m00054.AA CMGC 16-175 17 4.1e-34 108.82 In-house 1-296 (513) Show / Hide 
Range on Protein: 16-175
Range on HMM: 1-296/513
Sequence Identity: 17% (53 aa)

LVFNQVIAHGSYGIVFLVYS--------------IQYQSYFAVKQVP-EKMFHEQ----------------EVRCLMEL-----------------DDIR
    ..| .|.||.|.  .               .... . |.| .  .. ..||                |...|..|                 ..  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVYLYKYFKIDD-----------------CYYFVMEYCPNDLEHFLNTKK---------MISEEV------------QRNIM------KEVLLSVK--VC
|| || .|. ..                 . |.|.||...|| ...  ..           || .             ...|      . .| ..|   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HDNH--IAHRDIKPSNFLID--------------------KYGRIRLSDFGLST-FQTY---------------------DEKCSEYVGTHFFMAPEI
| .   | |||.||.| ||.                    | ||... ||||.. . ..                      .  ..|| | .  ||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI
Kinase 97166.m00054.AA MARK 17-263 30 7.8e-33 104.78 In-house 2-262 (262) Show / Hide 
Range on Protein: 17-263
Range on HMM: 2-262/262
Sequence Identity: 30% (81 aa)

VFNQVIAHGSYGIVFLVYSIQYQSYFAVKQVP-EKMFH-------EQEVRCLMELDDIRIVYLYKYFK--IDDC-YYFVMEYCPN-DLEHFLNTK--KMI
 . ..| ||||. | |. .. ..  .|.| .. .|..        . |.. .. ||   |. |....      .  |..|||... .| ...  .    .
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL

SEEVQRNIMKEVLLSVKVCHDNHIAHRDIKPSNFLIDKYG--RIRLSDFGLSTFQTYDEKCSEYVGTHFFMAPEIYAHKKDGSSYNPILSDIWAIGVTLY
.||  | | . ..  |. ||...|.|||||| | |||. |   | ..|||.|.  . ..| ..  ||  .|||||   |.    |.    |||. || ||
HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKP----YDGPKVDIWSLGVVLY

FIATRRFPFQ--SYDFNTLQEQIMSAQYDEKLIPDL--RLRFIISNCLQVDPLRRPSISEILLMPYF
|. . .|||   ..|...|...| . .||    . .   .| .|.  |.|.| .||.|.||.  | .
FMVCGYFPFDGDTQDYKELYKKILRGKYD--IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 97166.m00054.AA TyrKc 16-263 20 9.5e-12 -32.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 16-263
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

LVFNQVIAHGSYGIVFL-VYSIQYQSYF-AVKQVP---EKMFHEQEVRCLMEL--DDIRIVYLYKYFKID-------DCYYFVMEYCPN-DLEHFLNTKK
....... .| .|.|.. ...     .  ||| .    ...|. .| | ...|  .   || || .   .       . .. ||||.|. || ..|  ..
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDAREDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

M-ISEEVQRNIMKEVLLSVKVCHDNHIAHRDIKPSNFLIDKYGRIRLSDFGLSTFQTYD----EKCSEYV-----GTH-----FFMAPEIYAHKKDGSSY
  .. .   ...  .       |.... |||.   | |... .... |||||| . . |    |  . |.     |..       ||||      . . .
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGKF

NPILSDIWAIGVTLYFIATR-RFPFQS-----YDFNTLQEQIMSAQYDEKLIP---------DLRLRFIISNCLQVDPLRRPSISEILLMPYF
. . ||.|. ||... | |.   |         .   . |....  . ..               .  |.. | . ||  ||. |||    .|
T-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 97166.m00054.AA CMGC 240-263 37 1.8e-07 19.62 In-house 490-513 (513) Show / Hide 
Range on Protein: 240-263
Range on HMM: 490-513/513
Sequence Identity: 37% (9 aa)

ISNCLQVDPLRRPSISEILLMPYF
....|| || .|......| .|||
LKKMLQYDPDKRITAEQALQHPYF