81732.m00008

Species: T.vaginalis
Alias: 81732.m00008, TvagK0147
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
81732.m00008.AA Protein None 128 None Fasta, JSON
81732.m00008.kin_dom Protein Kinase Domain None 99 None Fasta, JSON

Protein domain

Protein domains of 81732.m00008.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase 81732.m00008.AA Pkinase 1-91 35 1.5e-25 91.42 Pfam 79-182 (293) Show / Hide
Range on Protein: 1-91
Range on HMM: 79-182/293
Sequence Identity: 35% (38 aa)

MEYCPS-----DLERVMK--QQKLF--SKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKYGRL----KIGDFGLSSV--YDDQYTCDLFKGTII
||||.      || ....  ... |  | .|. .| ..... .  |||..| |.|.||.|.|.|. | .    ||.||||. .  |  .  .. | ||. 
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW

YMAPEV
||||||
YMAPEV

Kinase 81732.m00008.AA AGC 1-99 21 3.1e-25 60.82 In-house 112-282 (395) Show / Hide
Range on Protein: 1-99
Range on HMM: 112-282/395
Sequence Identity: 21% (37 aa)

MEYCP---------SDLERVMKQQK-----LFSKEELLKYSKE-------VVQSVCACHS-KNIAHCD-IKPANFLVDKYGRLKIGDFGLSSV--YDD--
|||.|          ..|  . .|.      |. |.   |  |       .|  .   || ..| | | .|| | | |. | .|. ||||. .   |.  
MEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEK

-----------------------------------------------QYTCDLFKG--TIIYMAPEVFESEDYNP
                                               . ..  | |  |  |||||..    |..
GQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGK

Kinase 81732.m00008.AA CAMK 1-97 20 5.6e-24 73.53 In-house 136-310 (425) Show / Hide
Range on Protein: 1-97
Range on HMM: 136-310/425
Sequence Identity: 20% (36 aa)

M---EYCPSD------LERVMKQ--------------QKLFSKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKY-----------------GRL
|   |||.        .... ..               . |. .|  .| . ... |  |||.||.|.|.|| | |.|.                  . .
MEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNI

KIGDFGLSSVYDD------------------------QYTCDLFKGTIIYMA-PEVFES-------------EDY
|| |||.. ..|.                           .  | ||  ||| |||...             ..|
KIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPY

Kinase 81732.m00008.AA Ciliate-E2 1-98 26 1.3e-21 70.95 In-house 113-265 (365) Show / Hide
Range on Protein: 1-98
Range on HMM: 113-265/365
Sequence Identity: 26% (42 aa)

MEYCPS-DLERVMKQQKLFS-----------KEELLKYSKEVVQ---------------SVCACHSKN-IAHCDIKPANFLVDKYGRLKIGDFGLSSVYD
||||   ||.  .|..|...            .| ....|...|                .  .|||| | | |||| | |.     .|| |||||  ||
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYD

DQ----------YTCDLFK-----------------------GTIIYMAPEVFESEDYN
|.          . .   |                       ||  |||||......|.
DDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYD

Kinase 81732.m00008.AA Ciliate-E2-Unclassified 1-98 30 1.7e-21 71.35 In-house 100-244 (352) Show / Hide
Range on Protein: 1-98
Range on HMM: 100-244/352
Sequence Identity: 30% (44 aa)

MEYCPS------------------DLERVMKQQKLFSKEELL-----KYSKEVVQSVCACHSKN-IAHCDIKPANFLVDKYG---RLKIGDFGLSSVYDD
||||.                   || . |||.| |. .. .     .| ....|  . .|.|| | | |||| | |.|. |   ..|| |||.|. |..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

QYTCDLFK-----------------GTIIYM----APEVFESEDYN
.. || ..                 ||..||    ||||.... |.
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYD

Kinase 81732.m00008.AA ULK 1-98 29 1.8e-21 71.8 In-house 99-233 (329) Show / Hide
Range on Protein: 1-98
Range on HMM: 99-233/329
Sequence Identity: 29% (40 aa)

MEYCPS-DLERVMKQQKL----------FSKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKY------------GRLKIGDFGLSSVYD-D---
||||.  |||  .|..|           .| .| ... |  ..   . |..|| |.||||.| |...             |.|||.|||.. . | |   
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

---QYTCD---LFKGTIIYMAPEVFE----SEDYN
    .||    ...|| .||||....     ..|.
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYY

Kinase 81732.m00008.AA CAMKL 37-98 40 3.6e-21 64.19 In-house 143-213 (297) Show / Hide
Range on Protein: 37-98
Range on HMM: 143-213/297
Sequence Identity: 40% (29 aa)

CHSKNIAHCDIKPANFLVDKYG--RLKIGDFGLSSVYDD-----QYTCDLFKGTIIYMAPEVFES--EDYN
|||..|.| |||| | |.|. |   .|| |||.|  |..       ... | |.  |||||.|..  ..|.
CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYD

Kinase 81732.m00008.AA ULK 1-98 29 1.1e-19 66.51 In-house 96-229 (324) Show / Hide
Range on Protein: 1-98
Range on HMM: 96-229/324
Sequence Identity: 29% (40 aa)

MEYCPS-DLERVMKQQKL---------FSKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKY------------GRLKIGDFGLSSVYDD-----
||||.  |||  .|..|          .| .| ... |  ..   . |..|| |.||||.| |. .             |.|||.|||.. . |.     
MEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQ

--QYTCD---LFKGTIIYMAPEVFE----SEDYN
   .||    . ||| .||||....     ..|.
QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYY

Kinase 81732.m00008.AA CMGC 1-76 19 3.2e-19 58.98 In-house 134-283 (513) Show / Hide
Range on Protein: 1-76
Range on HMM: 134-283/513
Sequence Identity: 19% (29 aa)

MEYCPSDLERVMKQQK---------LFSKEE------------LLKYS------KEVVQSVC--ACHSKN--IAHCDIKPANFLVD--------------
.||.. || ...|...          .|  .              ...      . . ...    |||..  | |.|.||.| |..              
FEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSE

------KYGRLKIGDFGLSSVYDDQ------------------------YT
      | |||||.||||.  |..                         ||
DWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYT

Kinase 81732.m00008.AA Ciliate-E3 1-68 41 5.6e-18 52.91 In-house 83-153 (202) Show / Hide
Range on Protein: 1-68
Range on HMM: 83-153/202
Sequence Identity: 41% (30 aa)

MEYCPS-DLERVMKQQKLFSKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKYG---RLKIGDFGLS
.|||   ||   .||| . .......  ....|.. | |.||| | |||| |.||||      .||.|||.|
QEYCSNGDLYHYIKQQNK-TQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGES

Kinase 81732.m00008.AA TKL 38-99 23 4.1e-16 54.53 In-house 149-252 (364) Show / Hide
Range on Protein: 38-99
Range on HMM: 149-252/364
Sequence Identity: 23% (24 aa)

HS--------KNIAHCDIKPANFLVDKYGR--------------LKIGDFGLSSVYDDQYTCDL--------------------FKGTIIYMAPEVFESE
||        ..|.|.|.|..| |||. ..              .||.||||| . .                             ||. .|||||.. .
HSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQ

DYNP
....
MNYT

Kinase 81732.m00008.AA S_TKc 1-125 15 3.2e-07 -70.93 SMART 1-231 (231) Show / Hide
Range on Protein: 1-125
Range on HMM: 1-231/231
Sequence Identity: 15% (38 aa)

M-----------------------------------------------------------------EYCPS---DLERVMKQQKL------FSKEELLKY
                                                                  |||.    || ...|...       |.  .  .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

SKEVVQSVCACHSKNIAHCDIKPANFLVDKYGRLKIGDFGLSSVYDDQYTCDLFKGTIIYMAPEVFESEDYNP------------------------IIV
 ..... .  |||..| |.|.||.| |.|.  ..||.||||. ..      . | ||  ||||||.    |..                        . .
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFPQMQM

SIQVLG--------------MVALRSTLPNTCE-------FDTL
 ....|                . | |     .          .
MFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF