Gene 94426.m00144 (T.vaginalis)

94426.m00144

Species: T.vaginalis
Alias: TvagK0243, 94426.m00144
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94426.m00144.AA Protein None 230 None Fasta, JSON
94426.m00144.kin_dom Protein Kinase Domain None 177 None Fasta, JSON

Protein domain

Protein domains of 94426.m00144.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase 94426.m00144.AA Pkinase 1-177 28 7.4e-43 152.61 Pfam 77-293 (293) Show / Hide 
Range on Protein: 1-177
Range on HMM: 77-293/293
Sequence Identity: 28% (62 aa)

MLMEYCPW-----DLSRYIK--KNRCV--EDKYMAKYCYEILKAIKACHDLNIAHSDIKPSNLLIDNYGRI----KVCDFGLSS---YQNDQSSKSDYKG
| ||||.      ||..||.  ...|.  ...   .|.|.||.... ||. .| | |.||.|.|||| | |    |.|||||.    | |..   ... |
MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCG

TLLFLPPEAFKGKPYNLLKADVWAIGATFYFMATGNYPFNAT------SYLNYVRMINSGEIPTEKISD---------------------IYLRDVIEHC
|. ...||  .| .|   |.|.|..| ..| |..|. ||         . .  ...| ..... .   .                       ..|.|. |
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

LVIEPEYRATVDELLELPYF
|   |. | | ...|. |.|
LCKDPKKRPTAEQILQHPWF
Kinase 94426.m00144.AA CAMK 1-177 20 5.8e-42 132.53 In-house 134-425 (425) Show / Hide 
Range on Protein: 1-177
Range on HMM: 134-425/425
Sequence Identity: 20% (60 aa)

MLM---EYCPW-----DLSRYIKKN-----------RCVEDKYM-----AKYCYEILKAIKACHDLNIAHSDIKPSNLLIDNY-----------------
| |   |||.      ||  ||...            . |....     ..|   |. |.. ||..||.| |.|| |.|.|.                  
MVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNN

GRIKVCDFGLSSYQND------------------------QSSKSDYKGTLLFLP-PEAFKG-------------KPYNLLKADVWAIGATFYFMATGNY
. ||..|||.. . ..                            ... ||. . . || ..|             |||   |.|.|..|   |.| .| .
NNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYP

PFNAT-------------SYLNYVRMINSGEI--PTEKISDIY----------------------LRDVIEHCLVIEPEYRATVDELLELPYF
||..              .. .  ..| .|.   | ...|.|                        .| | ..|. .|| |.|... |. | .
PFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94426.m00144.AA Ciliate-E2-Unclassified 3-177 23 3.1e-41 140.77 In-house 100-352 (352) Show / Hide 
Range on Protein: 3-177
Range on HMM: 100-352/352
Sequence Identity: 23% (60 aa)

MEYCP-WDLSRYIKKN-----------------RCVEDKYMA-----KYCYEILKAIKACHDLN-IAHSDIKPSNLLIDNYG---RIKVCDFGLSSYQND
||||.  ||. ||||.                 ...... ..     .|...||.... .|  | | | ||||.|.|.|| |   .||..|||.|.....
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

QSSKSDYK-----------------GTLLFL----PPEAFKGKPYNL---LKADVWAIGATFYFMATGNYPFNATSYLN----------------YVRMI
.. .  ..                 ||. ..    .|| ..|. |.     |.|.|. |  .|.| .|.|||.....                  . . |
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

NSGEIPTEK--------ISDIYLRDVIE----HCLVIEPEYRATVDELLELPYF
. ..|   |        ...    | |.     .|.  |..| | ...|. |.|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94426.m00144.AA Ciliate-E2 1-177 22 1.2e-38 130.32 In-house 111-365 (365) Show / Hide 
Range on Protein: 1-177
Range on HMM: 111-365/365
Sequence Identity: 22% (61 aa)

MLMEYCPW-DLSRYIKKNR-----------CVEDKYMAKYCYEILK---------------AIKACHDLN-IAHSDIKPSNLLIDNYGRIKVCDFGLSSY
. ||||   ||  |||.|.           .  .| .... ..||.               |.. .|  | | | ||||.|.|.     ||..||||| .
LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKK

QNDQ----------SSKSDYK-----------------------GTLLFLPPEAFKGKPY--------NLLKADVWAIGATFYFMATGNYPFNATSYLNY
..|.            . . |                       ||. ...|| ..||.|           |.|.|..| ..|.| .|..||        
YDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------

VRMINSGEIPTE----------------KISDIYLR--DVIEH----CLVIEPEYRAT-VDELLELPYF
 . |  ..|                   .  .. .   | |      .|. .|| | |  ...|. |.|
QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94426.m00144.AA CAMKL 1-177 29 8.5e-38 118.1 In-house 98-297 (297) Show / Hide 
Range on Protein: 1-177
Range on HMM: 98-297/297
Sequence Identity: 29% (60 aa)

MLMEYCP---WDLSRYIKKNRC----VEDKYMAKYCYEILKAIKACHDLNIAHSDIKPSNLLIDNYG--RIKVCDFGLSSYQND-----QSSKSDYKGTL
. ||||.    ||  ||.|...     . .   .|   |. |.. ||...|.| |||| |.|.|. |   ||..|||.| .. .         .   |..
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

LFLPPEAFKG--KPYNLLKADVWAIGATFYFMATGNYPFNATS---------YLNYVRMINSGEIPTEKISDIYLRDVIEHCLVIEPEYRATVDELLELP
 . .|| |.|  |||.  |.|.|..| . |.| .|..||.. .         ||    |.  ...|  .  .  .|| | . |.  ||.|.|...... |
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

YF
 .
WM
Kinase 94426.m00144.AA ULK 3-177 28 2.7e-34 117.18 In-house 99-329 (329) Show / Hide 
Range on Protein: 3-177
Range on HMM: 99-329/329
Sequence Identity: 28% (67 aa)

MEYCPW-DLSRYIKKN-RCVEDKY---------MAKYCYEILKAIKACHDLNIAHSDIKPSNLLIDNY------------GRIKVCDFGLSSY-QND---
||||.  ||. ||||| .. ||.            .... || . |. |. || | ||||.| ||.|             |..|..|||..   .||   
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

-QSSKSDY-----KGTLLFLPPEAFK----GKPYNLLKADVWAIGATFYFMATGNYPFNATSYLNYV-----RMINSG--------EIPTE--------K
 |  ..       .|| |.  |. ..    .|||.  |.|.| .|  || | .| .||.|  .  ..     . || .         .|..        .
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

ISDIYLRDVIEHCLVIEPEYRATVDELLELPYF
||.  ..| |  .|..... | . .||.. | |
ISPE-CKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 94426.m00144.AA STE 1-177 22 5.9e-34 117.32 In-house 114-359 (359) Show / Hide 
Range on Protein: 1-177
Range on HMM: 114-359/359
Sequence Identity: 22% (57 aa)

MLMEYCP-WDLSRYIK-KNRCVE-------------DKYMAKYCYEILKA-IKACHDLNIAHSDIKPSNLLIDNYGRIKVCDFGLSSYQND---------
. |||..   |.  || |  | .              .  |..|..|||.  .  |...| | ||||.| |.     .| ||||...  .|         
ICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNN

-------QSSKS-DYKGTLLFLPPEAFKG------KPYNLLKADVWAIGATFYFMATGNYPFNATSYL----NYVRMINSGE---------IPTEKISD-
       ...|.    ||  .  ||  ..      |.|.  |.|.| .| |   ||||..|.   ...    .  ... ...          |  .. | 
IIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDH

---------------------IYLRDVIEHCLVIEPEYRATVDELLE--LPYF
                       ..| |..||...|. |.|...||.   | .
LSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 94426.m00144.AA ULK 3-177 27 1.1e-31 109.76 In-house 96-324 (324) Show / Hide 
Range on Protein: 3-177
Range on HMM: 96-324/324
Sequence Identity: 27% (63 aa)

MEYCPW-DLSRYIKKN-RCVEDKY---------MAKYCYEILKAIKACHDLNIAHSDIKPSNLLIDNY------------GRIKVCDFGLSSY-QND---
||||.  ||. ||||| .. | .            .... |. . |. |. || | ||||.|.|| |             |..|..|||..   .|.   
MEYCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNME

QSSKSDYK------GTLLFLPPEAFK----GKPYNLLKADVWAIGATFYFMATGNYPFNATSYLNYV----RM----------INSGEIPTE------KI
|     ..      || |.  |. ..    .|||.  |.|.| .|  || | .| |||..  . ...    ..          |.   |.        ||
QQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKI

SDIYLRDVIEHCLVIEPEYRATVDELLELPYF
|.  ..| |  .|..... | . .|... | |
SPE-CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 94426.m00144.AA NEK 3-177 28 1.2e-26 91.16 In-house 85-286 (286) Show / Hide 
Range on Protein: 3-177
Range on HMM: 85-286/286
Sequence Identity: 28% (58 aa)

MEYCPW--DLSRY---IKKNR----CVEDKYMAKYCYEILKAIKACHDL-----NIAHSDIKPSNLLIDNYGR----IKVCDFGLSSYQNDQSSKSD--Y
||||    ||..    |||..      | ..  .... ...|.| .||      .| | ||||.|. ... ..    .|. |||.|  .|. ...    .
MEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQ

KGTLLFLPPEAFKGKPYNLLKADVWAIGATFYFMATG--NYPFNAT--SYLNYVRMINSGEIPTEKISDI--Y---LRDVIEHCLVIEPEYRATVDELLE
 ||  .. || ...||||  |.|.|..|   | |.|   . ||.|.  . .. .  |  | .  ..|..   |   |...|. .|  .|| | .....||
VGTPYYMSPEVCQNKPYN-NKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKG-PQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILE

LPYF
.|. 
MPFI
Kinase 94426.m00144.AA CMGC 1-123 20 1.3e-23 73.69 In-house 132-342 (513) Show / Hide 
Range on Protein: 1-123
Range on HMM: 132-342/513
Sequence Identity: 20% (44 aa)

MLMEYCPWDLSRYIKK----------------------------NRCVEDKYMAKYCYEILKAIK--ACHDLN--IAHSDIKPSNLLIDN----------
. .||...|| .|||.                             ..    .   |.| ||...|   ||  .  | | |.||.|.||..          
LVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMW

----------YGRIKVCDFGLSSYQNDQSS----------------------KSDYKGTLLFLPPEAFKGKPYNL---------LKADVWAIGATFYFMA
           ||.|.|||||. . .. |.                       ..|  |.   .||   | ..            . |.|..|  |. | 
KSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMY

TG-------NYPF
||        .|.
TGYQSLIFRGKPL
Kinase 94426.m00144.AA S_TKc 2-177 22 8.8e-21 76.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 2-177
Range on HMM: 1-231/231
Sequence Identity: 22% (58 aa)

L----------------------------------------------------------------MEYCPW---DLSRYIKKNRC------VEDKYMAKY
                                                                 ||||.    || .||||...            ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

CYEILKAIKACHDLNIAHSDIKPSNLLIDNYGRIKVCDFGLSSYQNDQSSKSDYKGTLLFLPPEAFKGKPYNLLKADVWAIGATFYFMATGNYPFNATSY
.|.|..|.. ||...| | |.||.|.|.|.  .||.|||||.         . . ||. ...|| .   .|.  |.|.|..| ..| |..|  ||     
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP----

LNYVRMINSGEIPTEKISDIYLRDVIEHCLVIEPEYRATVDELLE-------LPYF
 .. .|..          .  ..| |..||. .|| | |. |.|.        |.|
-QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94426.m00144.AA MARK 84-177 31 3.3e-18 56.27 In-house 167-262 (262) Show / Hide 
Range on Protein: 84-177
Range on HMM: 167-262/262
Sequence Identity: 31% (31 aa)

GTLLFLPPEAFKGKPYNLLKADVWAIGATFYFMATGNYPFNATS--YLNYVRMINSGEIP-TEKISDIYLRDVIEHCLVIEPEYRATVDELLELPYF
||. . .|| |..|||.  |.|.|. |   ||| .|..|| ...  | .  . |..|. .   ..|.  .|. |   |.. ||.|.|..|... | .
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSK-ECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 94426.m00144.AA MARK 1-70 38 5.2e-18 55.62 In-house 79-153 (262) Show / Hide 
Range on Protein: 1-70
Range on HMM: 79-153/262
Sequence Identity: 38% (29 aa)

MLMEYCP-WDLSRYIKKN--RCVEDKYMAKYCYEILKAIKACHDLNIAHSDIKPSNLLIDNYG--RIKVCDFGLS
. |||..  .|  |||.   .. . .   ...  |. |.. ||. ||.| |||| |.|||  |   || .|||.|
LIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFS
Kinase 94426.m00144.AA CMGC 143-177 31 4e-06 15.04 In-house 479-513 (513) Show / Hide 
Range on Protein: 143-177
Range on HMM: 479-513/513
Sequence Identity: 31% (11 aa)

EKISDIYLRDVIEHCLVIEPEYRATVDELLELPYF
.|  |  ..| .. .|...|. | |... |. |||
RKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 94426.m00144.AA TyrKc 1-175 17 9.6e-05 -145.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-175
Range on HMM: 1-280/280
Sequence Identity: 17% (48 aa)

M---------------------------------------------L------------------------------MEYCPW-DLSRYIKKNRC-VEDK
                                              |                              |||.|. ||  |..|.|  .  |
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

YMAKYCYEILKAIKACHDLNIAHSDIKPSNLLIDNYGRIKVCDFGLSSYQNDQ----SSKSDYK------GTLLF----LPPEAFKGKPYNLLKADVWAI
 . ..|. | .     |. |. | |.   | |... ...|..||||| .  |      ||. |.      |  ..    ..||... . ..  | |||. 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKSDVWSF

GATFYFMATG----NYP-----FNATSYLNYVRMINSGEIPTEKI------SDIYLRDVIEHCLVIEPEYRATVDELLELP
| . . . |      .       ...  ..||.  .  ..| .            . .... |   .|| | |  |. |. 
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF