Gene 85522.m00037 (T.vaginalis)

85522.m00037

Species: T.vaginalis
Alias: 85522.m00037, TvagK0176
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
85522.m00037.AA Protein None 313 None Fasta, JSON
85522.m00037.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 85522.m00037.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 85522.m00037.AA S_TKc 14-257 30 3.5e-74 253.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-231/231
Sequence Identity: 30% (79 aa)

MNIEQSIAVGGFGEIFLVYSEQYKMHFAMKKIESKFFNRTEIDVLQSIDNNNIVRLYSYFELGEHVFLLMEYCPS---DLYQYVKENED------IEPEK
  | . |  |.||. ....    . ..|.|.|      | ||..|.. .  |||.|| .|.  .|... ||||.    ||..| |..        . .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LRKYIQEMVLSIKACHDYKIAHNDIKPSNFLLDKYGRVKVCDFGLSMIHEEDSLSKSYKGTLFFMAPEQLRRTEYNPIKADIWSLGVTMFYMATKTYPFI
 |.|...... .. ||. .| | |.||.| |||.  ..|.|||||. .       ... ||...|||| |    |.. |.|.||.|.... |..   || 
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

ASHPDLILKLIDNGNYPIFAVKNPNLRRIIMKCLQVDPSQRPTCEEILA-------MPYF
  ......|.|            | .. .|.||||.||..|||. |.|.       .|.|
--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85522.m00037.AA CAMK 19-257 17 2.1e-65 209.42 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-257
Range on HMM: 1-425/425
Sequence Identity: 17% (75 aa)

SIAVGGFGEIFLVYSEQYK------------MHFAMKKIE---------------------------------SKFFNRTEIDVLQS-------IDNNNI
 .  |.||. .|..  . .             ..|.| |.                                 .. . | ||.....       .|  ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLYSYFE------------LGEH--------VFLLM---EYCPS-----DLYQYVKENED---------------IEPEKLRKYIQEMVLSIKACHDYK
..|| ..|              ..        ... |   |||.      ||..|..|...               .. .  |.|.. ..  .. ||. .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHNDIKPSNFLLDKY-----------------GRVKVCDFGLSMIHEE------------------------DSLSKSYKGTLFFMA-PEQLRR-----
|.| |.|| | |||.                  . .|..|||.. . ..                        . . | . ||. .|| || |..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------TEYNPIKADIWSLGVTMFYMATKTYPFIAS-------------HPDLILKLIDNGNY--PIFAVKNPN----------------------LR
         .| . |.|.||.|| .. | . ..|| ..             ..  ... | .|.|  | . ....                        .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

RIIMKCLQVDPSQRPTCEEILAMPYF
  | |.|||||..|.|.|..|. | .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 85522.m00037.AA Pkinase 14-257 25 2.5e-60 211.55 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

MNIEQSIAVGGFGEIFLVYSEQYKMHFAMKKIESKFFNR---------TEIDVLQSIDNNNIVRLYSYFELGEHVFLLMEYCPS-----DLYQYVK--EN
  |.. |  |.||. .. .   .   .|.|.|. .  .          .|| ......  |||||| .|| . |. . ||||.      ||. |..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EDI--EPEKLRKYIQEMVLSIKACHDYKIAHNDIKPSNFLLDKYGRV----KVCDFGLSMI--HEEDSLSKSYKGTLFFMAPEQLRRTEYNPIKADIWSL
  .  ... ...|. ...  .. ||. .| | |.||.|.|.|. | .    |.|||||.    .  .|  ... ||...|||| .|  .| . |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTMFYMATKTYPFIAS----HPDLILKLIDNGNYPIFAVKN------------------------PNLRRIIMKCLQVDPSQRPTCEEILAMPYF
|.....|...  ||  .    . .  ...|..  .|..                            .... .| .||..||..|||.|.||  |.|
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85522.m00037.AA AGC 14-257 20 3.5e-59 150.65 In-house 1-395 (395) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-395/395
Sequence Identity: 20% (82 aa)

MNIEQSIAVGGFGEIFLVYSE------QYKMHFAMKKIE-----------SKFFNRTE------------IDVLQSID----------NNNIVR-LYSYF
 ..   |  |.||. .||         . .  .|||...               . ||             ..|. ..          . .||. |.. |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ELGEH--VFLLMEYCP----------S-DLYQYVK---ENEDIEPEKLRKYIQE-------MVLSIKACHD-YKIAHND-IKPSNFLLDKYGRVKVCDFG
.  .|  ....|||.|            .|... .    .   . |  | |. |       .|| .   |.  .| | | .|| | |||. | .| .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSMIHEEDS---------------------------------------------------LSKSYKG--TLFFMAPEQLRRTEYNPIKADIWS--LGVTM
|. .   |                                                    . ..  |  |  .|||| |    |..  .|.||  ||. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

FYMATKTYPFIASHPD----------LILKLIDNGNYPIFAVKN----------------PNLRRIIMKCLQVDPSQRPTC----------EEILAMPYF
. | |   || .  |.           . ..| ||.| |.                    |... .| |.|..||..|..|          ||| . |.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 85522.m00037.AA CAMKL 15-257 26 1.8e-57 181.87 In-house 2-297 (297) Show / Hide 
Range on Protein: 15-257
Range on HMM: 2-297/297
Sequence Identity: 26% (80 aa)

NIEQSIAVGGFGEIFLVYSEQY-KMHFAMKKIE-SKFFN-------------------RTEIDVLQSID---NNNIVRLYSYFELGEH------VFLLME
.|.. .  |.||.  |   ... . . |.| |. .|  |                   | ||  .....     ||..||  .|  ||      ..| ||
RIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVME

YCPSD---LYQYVKENED----IEPEKLRKYIQEMVLSIKACHDYKIAHNDIKPSNFLLDKYG--RVKVCDFGLSMIHEE-----DSLSKSYKGTLFFMA
||..    |..|......    ....  |.| . .|  .. ||. .|.| |||| | |||. |   .|..|||.| ....     . . |   |.. .||
YCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMA

PEQLRR--TEYNPIKADIWSLGVTMFYMATKTYPFIASHPD-------LILKLIDNGNYPIFAVKNP-NLRRIIMKCLQVDPSQRPTCEEILAMPYF
|| . .  ..|.  |.||||.||... | . ..|| . .         . .. |  | | .   . .  .|..| | |||.|..|||...|.  | .
PEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 85522.m00037.AA Ciliate-E2 14-257 21 2.1e-53 181.64 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-365/365
Sequence Identity: 21% (80 aa)

MNIEQSIAVGGFGEIFLV--YSEQYK---------------------MHFAMKKIESK--FFNRTEIDVLQ----------------SIDNNNIVRLYSY
 .. . |  |.|| ....  ...|..                     . .||| .. .  ..   ||....                .....||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--LGEHVFLLMEYCPS-DLYQYVKENEDIEP----------EKLRKYIQEMVLS----------------IKACHDYK-IAHNDIKPSNFLLDKYGRV
|.    ....| ||||   ||..| |.|   ..          || .||| . .|.                .. .|  . | | ||||.| |.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KVCDFGLSMIHEED--------------------------------SLSKSYKGTLFFMAPEQLRRTEY--------NPIKADIWSLGVTMFYMATKTYP
|..||||| .  .|                                 . ... ||. .|||| |.. .|           |.|||||||....| .. .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FIASHPDLILKLIDNGNYPIF----------------AVKNPNLR--RIIMK----CLQVDPSQRPT-CEEILAMPYF
|        .. | .... ..                  |.  .    .| |    .||.||..|.|  |.||  |.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85522.m00037.AA MARK 15-257 29 1e-46 150.86 In-house 2-262 (262) Show / Hide 
Range on Protein: 15-257
Range on HMM: 2-262/262
Sequence Identity: 29% (77 aa)

NIEQSIAVGGFGEIFLVYSEQYKMHFAMKKIE----SKFFN----RTEIDVLQSIDNNNIVRLYSYFE--LGEH-VFLLMEYCPS-DLYQYVKEN--EDI
 . . |  |....  |. .  .. ..| | .|    ... .    . ||......|  ||..|. ..|    .| ..| |||... .||.|.|.     .
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL

EPEKLRKYIQEMVLSIKACHDYKIAHNDIKPSNFLLDKYG--RVKVCDFGLSMIHEEDSLSKSYKGTLFFMAPEQLRRTEYNPIKADIWSLGVTMFYMAT
. |  |.. . .|  .. ||.  |.| |||| | |.|. |   .| .|||.| . ..... ..  ||. .|||| . . .|.  |.||||||| ...| .
HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVC

KTYPFIASH--PDLILKLIDNGNYPIFAVKNPNLRRIIMKCLQVDPSQRPTCEEILAMPYF
 ..|| ..      . | | .|.|.|.    . .| .| . |.|.|..|||.|||.  | .
GYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85522.m00037.AA ULK 14-257 25 5.8e-46 159.01 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-324/324
Sequence Identity: 25% (82 aa)

MNIEQSIAVGGFG-EIFLVYSEQY---KMHFAMKKIE----SKFFNR-----------TEIDVLQSID------NNNIVRLYSYFELGEH--VFLLMEYC
 .. . .  | ||   .  . ..    . ..| |.|.    .|. |.            || ... ..      . .||.|| .||   |  ... ||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

PS-DLYQYVKENED---------IEPEKLRKYIQEMVLSIKACHDYKIAHNDIKPSNFLLDKY------------GRVKVCDFGLSMIHEED----SLSK
.  || || |.|           .. .. .....  .   |. |. .| | ||||.| |. .             |..|..|||.. . ...     . .
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SYK------GTLFFMAPEQLR----RTEYNPIKADIWSLGVTMFYMATKTYPFIASHPDLIL---KLIDNG--------NYPIFAVKN-------PNLRR
...      ||  .|||. |     . .|. .|.||||||. ...| .  ||| ..  |..|   |||.||        | ||   |.       |... 
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IIMKCLQVDPSQRPTCEEILAMPYF
.|...||.|...| . |||...| |
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85522.m00037.AA ULK 40-257 24 4e-45 155.48 In-house 31-329 (329) Show / Hide 
Range on Protein: 40-257
Range on HMM: 31-329/329
Sequence Identity: 24% (73 aa)

FAMKKIE---SKFFN------------RTEIDVLQSID--------NNNIVRLYSYFELGEH--VFLLMEYCPS-DLYQYVKENED----------IEPE
.| |.|.    . .|            . ||.... ..        . |||.|| .||   |  ... ||||.  || || |.|            .. .
VACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQ

KLRKYIQEMVLSIKACHDYKIAHNDIKPSNFLLDKY------------GRVKVCDFGLSMIHEED----SLSKSYK------GTLFFMAPEQLR----RT
. .....  .   |. |. .| | ||||.| |...             |..|..|||..   ..|     . ....      ||  .|||. |     . 
EAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQK

EYNPIKADIWSLGVTMFYMATKTYPFIASHPDLIL-----KLIDNG--------NYPIF-------AVKNPNLRRIIMKCLQVDPSQRPTCEEILAMPYF
.|.  |.||||||. ...| .  .|| |. .         |||.|.        . |.         .  |... .| ..||.|...| . ||....| |
PYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85522.m00037.AA Ciliate-E2-Unclassified 15-257 20 3.4e-44 151.2 In-house 2-352 (352) Show / Hide 
Range on Protein: 15-257
Range on HMM: 2-352/352
Sequence Identity: 20% (73 aa)

NIEQSIAVGGFGEIFLVYSEQYKMHFAMKKIESKFFNRT------------------EID-------------VLQSIDNNNIVRLYSYFELGEHVFLLM
.| . |  ||||...... .. |  .. .|. .|. ..                   ..               |..... .||... .|.  ..... |
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCPS-DLYQYVKENED-----------------IEPEKLR-----KYIQEMVLSIKACHDYK-IAHNDIKPSNFLLDKYG---RVKVCDFGLSMIHEED
|||.  || || |...                  .. .. .     .|. . .. .. .|  . | | ||||.| |.|. |   ..|..|||.|.  ...
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------------SLSKSYKGTLFFM----APEQLRRTEYNP---IKADIWSLGVTMFYMATKTYPFIASHPDL----------------ILKLIDN
                 ....  ||. .|    ||| |.. .|.    .|.||||||| ...| . .||| .   .                 ... | .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GNYPIFAVKN--------PNLRRIIM----KCLQVDPSQRPTCEEILAMPYF
.|. ..  ..        |.   .|     |.|...|..|.| |.||  |.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85522.m00037.AA CMGC 14-257 15 1.5e-41 133.74 In-house 1-513 (513) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-513/513
Sequence Identity: 15% (79 aa)

MNIEQSIAVGGFGEIFLVYS--------------EQYKMHFAMKKIESKFFNR-----------------TEIDVLQSI-----------------DNNN
  | . |  | .|. .  .                ... . |.||| ..| .                   ||  |. .                 . ||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVRLYSYFELGE-----------------HVFLLMEYCPSDLYQYVKENE---------DIEPEK------------LRKYI------QEMVLSIK--AC
||.|| .|   .                 |..| .||.. ||||| |.|            .. .             ....      . .  ..|   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HDYK--IAHNDIKPSNFLLD--------------------KYGRVKVCDFGLSM-IHEEDSL---------------------SKSYKGTLFFMAPEQLR
|  .  | | |.||.| |..                    | ||.|.|||||.  .|....                        .|  |..  ||| | 
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

RTEYNP---------IKADIWSLGVTMFYMATK-------TYPFIA----------------SHPDLILKLIDNGN------------------------
. ..            . |.||.|  .. | |.        .|.                   . ..| |.. . .                        
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

---------------------------------YPIFAV--------------------------------------------KNPNLRRIIMKCLQVDP
                                 .| .                                               .| ..  ..|.|| ||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

SQRPTCEEILAMPYF
..|.|.|..|..|||
DKRITAEQALQHPYF
Kinase 85522.m00037.AA STE 14-257 19 8.4e-39 134.67 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-359/359
Sequence Identity: 19% (70 aa)

MNIEQSIAVGGFGEIFLVYSE------QYKMH---------FAMKKIE----------------------SKFFNRTEIDVLQSID--NNNIVRLYSYFE
  . . |  |.||. .. .        . .           .|.|...                       .     ||....  .    |||. | ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

LG-------EHVFLLMEYCP-SDLYQYVKEN-EDIEP-------------EKLRKYIQEMVLS-IKACHDYKIAHNDIKPSNFLLDKYGRVKVCDFGLSM
 .       ..... |||..   | . .|.. .  .|             . ....... .    .  |. .| | ||||.| ||     || ||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

IHEE-----------------DSLSKSYKGTLFFMAPEQLRR------TEYNPIKADIWSLGVTMFYMATKTYPFIASHPDLILKLIDNGN---------
. ..                 .. ...  ||  .|||| ...       .|. .|.|||||| |.  |||  .|.   ||   . .| ...         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----YPIFAVKN----------------------PNLRRIIMKCLQVDPSQRPTCEEILA--MPYF
     |.   ..                      |...  | |||| ||..||| .. |    | .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 85522.m00037.AA TyrKc 14-257 21 2.6e-13 -7.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-280/280
Sequence Identity: 21% (61 aa)

MNIEQSIAVGGFGEIFL-VYSEQYKMHFAMKKIE----SKFFNRTEIDVLQSI--DNNNIVRLYSYFELG-------EHVFLLMEYCPS-DLYQYVKENE
   .. .  | |||... ...    .  | |..       |  . |. .. ..  .. |||||| .   .       | ....|||.|  || .| ....
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDF--MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

D-IEPEKLRKYIQEMVLSIKACHDYKIAHNDIKPSNFLLDKYGRVKVCDFGLSMIHEED--------SLSK----SYK--GTLFFMAPEQLRRTEYNPIK
. . ...| ..           |. .. | |.   | |... ..||..|||||  ...|          .|    . |    .  |||| ..  ... .|
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TK

ADIWSLGVTMFYMATKTYPFIAS------HPDLILKLIDNGNYPIFAVK---------NPNLRRIIMKCLQVDPSQRPTCEEILAMPYF
 |.|| ||.|. . |   .           .. .......|...               . . .|. .| . ||..||| .||    .|
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 85522.m00037.AA Pkinase_Tyr 135-194 32 0.000232 15.39 Pfam 143-205 (270) Show / Hide 
Range on Protein: 135-194
Range on HMM: 143-205/270
Sequence Identity: 32% (21 aa)

LLDKYGRVKVCDFGLSMIHEEDSLSKSYKGT-----LFFMAPEQLRRTEYNPIKADIWSLGVTMF
|... . ||.|||||.  ...|.   ..|..      . |||| ..  ... .| |.|| ||.|.
LVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFT-TKSDVWSFGVLMW
Kinase 85522.m00037.AA Pkinase_Tyr 54-97 32 0.001438 12.71 Pfam 53-101 (270) Show / Hide 
Range on Protein: 54-97
Range on HMM: 53-101/270
Sequence Identity: 32% (16 aa)

EIDVLQSI-DNNNIVRLYSYFE-LGEH--VFLLMEYCPS-DLYQYVKEN
|. .. .. .. ||||||      ||.  ... |||.|  ||. | ...
EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH
Kinase 85522.m00037.AA Pkinase_Tyr 228-247 30 1.117773 2.92 Pfam 243-262 (270) Show / Hide 
Range on Protein: 228-247
Range on HMM: 243-262/270
Sequence Identity: 30% (6 aa)

PNLRRIIMKCLQVDPSQRPT
. . .....| . ||..|||
DEIYDLMKQCWHYDPEDRPT