TVAG_470040

Species: T.vaginalis
Alias: TVAG_470040, TvagK1074
External Links:
Annotation:

Classification

Group: Other
Family: WNK

Sequence

Name Sequence Type Origin Length Description Download
TVAG_470040.AA Protein None 92 None Fasta, JSON
TVAG_470040.kin_dom Protein Kinase Domain None 71 None Fasta, JSON

Protein domain

Protein domains of TVAG_470040.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TVAG_470040.AA STE 2-72 20 4.5e-10 31.9 In-house 254-359 (359) Show / Hide
Range on Protein: 2-72
Range on HMM: 254-359/359
Sequence Identity: 20% (22 aa)

VGCLMLTLATGLEPY---SSLKTPFLFI--NALKN---------EIPPTEIDKIDD------------------PLLQSLVRSCFQPSTK-RPTARELLE
.||... .|||  |.   . ..  |...  ..  .         . ||.  |....                  | ..  .. |.|   . |||| .||.
LGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLK

--HPFF
  |||.
SEHPFI

Kinase TVAG_470040.AA WNK 35-72 30 1.1e-08 24.03 In-house 223-261 (261) Show / Hide
Range on Protein: 35-72
Range on HMM: 223-261/261
Sequence Identity: 30% (12 aa)

PTEIDKIDDPLLQSLVRSCFQPST-KRPTARELLEHPFF
|  ..|| .| .  ..  | . .   ||....||.| ||
PNSFQKIQNPEVKEIIEKCIRHNKEERPSIQQLLNHDFF

Kinase TVAG_470040.AA Pkinase 2-72 15 3.8e-08 29.88 Pfam 198-293 (293) Show / Hide
Range on Protein: 2-72
Range on HMM: 198-293/293
Sequence Identity: 15% (15 aa)

VGCLMLTLATGLEPYSSL-----KTPFLFINALKNEIPPTEIDKIDD-------------------PLLQSLVRSCFQPS-TKRPTARELLEHPFF
.||..  ...|  |...       ..   |.  .  ... .... ..                   . .......|...  .|||||...|.||.|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase TVAG_470040.AA STE11 50-72 54 8e-08 24.68 In-house 280-303 (303) Show / Hide
Range on Protein: 50-72
Range on HMM: 280-303/303
Sequence Identity: 54% (13 aa)

VRSCFQPSTK-RPTARELLEHPFF
.| ||..  | ||||..||.|||.
LRHCFEHDPKKRPTANQLLQHPFI

Kinase TVAG_470040.AA FRAY 49-72 57 9.4e-08 19.8 In-house 253-277 (277) Show / Hide
Range on Protein: 49-72
Range on HMM: 253-277/277
Sequence Identity: 57% (15 aa)

LVRSCFQ--PSTKRPTARELLEHPFF
....|.|  || ||||| |||.| ||
MIEKCLQKDPS-KRPTASELLKHKFF

Kinase TVAG_470040.AA CAMK 2-72 17 2.2e-07 19.06 In-house 320-425 (425) Show / Hide
Range on Protein: 2-72
Range on HMM: 320-425/425
Sequence Identity: 17% (19 aa)

VGCLMLTLATGLEPYS---------------SLKTPFLFINALKNEIPPTEIDKI--------DD-----------PLLQSLVRSCFQP-STKRPTAREL
.|... .. .|  |.                ...  |  | . | . || ....|        .|           .  ..|.|.. |.  .||.|. . 
CGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQC

LEHPFF
|.||..
LNHPWM

Kinase TVAG_470040.AA MST 59-72 57 4.6e-07 18.4 In-house 241-254 (254) Show / Hide
Range on Protein: 59-72
Range on HMM: 241-254/254
Sequence Identity: 57% (8 aa)

KRPTARELLEHPFF
.|.|| .||.|||.
QRWTAEQLLQHPFI

Kinase TVAG_470040.AA DyrkP 40-72 47 5.9e-07 18.22 In-house 290-323 (323) Show / Hide
Range on Protein: 40-72
Range on HMM: 290-323/323
Sequence Identity: 47% (16 aa)

KIDDPLLQSLVRSCFQ-PSTKRPTARELLEHPFF
. || .    ||.| |   |.||||.| |.||.|
RTDDHMFIDFVRQCLQIDFTRRPTAKEALQHPWF

Kinase TVAG_470040.AA MEK7 9-72 28 6.2e-07 19.57 In-house 200-269 (269) Show / Hide
Range on Protein: 9-72
Range on HMM: 200-269/269
Sequence Identity: 28% (20 aa)

LATGLEPYSSLKTPFLFINALKNE-IPPTEIDKIDD----PLLQSLVRSCFQ-PSTKRPTARELLEHPFF
||||. ||   .. |  .    |. ..|   ..       |. ...| .| |   ..||  |.|..||| 
LATGQYPYPGCDMEFEMMTKILNDNLEPPCLPEHMKYNFSPDFCQFVDKCLQKDHRMRPKYRMLMQHPFI

Kinase TVAG_470040.AA RCK 59-72 57 8.2e-07 17.34 In-house 285-298 (298) Show / Hide
Range on Protein: 59-72
Range on HMM: 285-298/298
Sequence Identity: 57% (8 aa)

KRPTARELLEHPFF
||.|| ..|.||.|
KRITAQQALQHPYF

Kinase TVAG_470040.AA AGC 46-72 21 2e-06 10.98 In-house 358-395 (395) Show / Hide
Range on Protein: 46-72
Range on HMM: 358-395/395
Sequence Identity: 21% (8 aa)

LQSLVRSCFQ-PSTKRPT----------ARELLEHPFF
...|.. ...   .||..          | |. .||.|
AKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF