87050.m00035

Species: T.vaginalis
Alias: TvagK0195, 87050.m00035
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
87050.m00035.AA Protein None 296 None Fasta, JSON
87050.m00035.kin_dom Protein Kinase Domain None 231 None Fasta, JSON

Protein domain

Protein domains of 87050.m00035.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 87050.m00035.AA S_TKc 27-257 26 1.1e-58 202.14 SMART 14-231 (231) Show / Hide
Range on Protein: 27-257
Range on HMM: 14-231/231
Sequence Identity: 26% (66 aa)

VVYLVYDPHYETHFALKVIPENRFRQSEINLMNEIDDPSIVRMYNYEHYEGFIYILYEFCQA---SLYSIIKQKNY------LDGDNLIRYSCGILKAIQ
.||.... .   ..|.|.|.  .  ..||... . . | ||..| . .  ...|.  |.|     .|...||....      ..     .| . |..|..
KVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALE

ACQNNKIAHLDIKPENILLDDYDRIKICDFGLSIKYENKDTELHYGGSIPFIAPEILDMKPYNPFKADIWSIGVTFFVMATGFFPWIGADETELCQNTLH
 | ...| | |.||||||||.  .||||||||. ..       .. |.  ..|||.|   .|...|.|.||.|.... |..|  |.   .. .. .. . 
YCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-

KKPQLELIRNHEFQKVIGCCLSKNPEERPTVDQLLN-------MAIF
          .|.   |  || |.||.|||. ..|.       .  |
---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 87050.m00035.AA CAMK 27-253 18 1.3e-48 154.36 In-house 9-421 (425) Show / Hide
Range on Protein: 27-253
Range on HMM: 9-421/425
Sequence Identity: 18% (75 aa)

VVYLVYDPHYE------------THFALKVIP---------------------------------ENRFRQSEINLMNE-------IDDPSIVRMYN-YE
.|.|... .              ...| |.|.                                   .. ..||..|.        .| | |...|  ||
KVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYE

----------------HYEG---FIYILY---EFCQA-----SLYSIIKQKNY---------------LDGDNLIRYSCGILKAIQACQNNKIAHLDIKP
                ..     ..|.     |.|.       |.. |... .               .. .   ||   |. |.. | ...|.|.|.||
DPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKP

ENILLDDYD-----------------RIKICDFGLSIKYENKDTEL------------------------HYGGSIPFIA-PEILDM-------------
||||||| .                  |||.|||...|.. .. ..                         . |. ...| ||.|               
ENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEE

KPYNPFKADIWSIGVTFFVMATGFFPWIGADETELC---------QNTLHK--KPQLELIRNH--------------------------EFQKVIGCCLS
||| ..|.|.||.||  ..| .|..|. | .. | |         .....|  | . . .  .                          | .  | ..| 
KPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQ

KNPEERPTVDQLLN
..||.|.|..| ||
VDPEKRMTIEQCLN

Kinase 87050.m00035.AA Ciliate-E2 40-257 24 4.1e-45 152.79 In-house 50-365 (365) Show / Hide
Range on Protein: 40-257
Range on HMM: 50-365/365
Sequence Identity: 24% (78 aa)

FALKVIPEN--RFRQSEINLMNEID----------------DPSIVRMYNYEH--YEGFIYILYEFCQA-SLYSIIKQK-----------NYLDGDNLIR
.|.|.. .|  ..  .||..|.||.                 | |..|| .     .  ||.  |.||  .|...||..           .|..    ..
YAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKY

YSCGILK---------------AIQACQNNK-IAHLDIKPENILLDDYDRIKICDFGLSIKYENK-----------------DTELHYG-----------
..  ||.               |.. . ... | | ||||||||.     |||.||||| || ..                 ||. ..|           
IMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMF

----GSIPFIAPEILDMKPY--------NPFKADIWSIGVTFFVMATGFFPWIGADETELCQNTLHKKPQL--------------ELIRNHEFQKVIGC-
    |. .. ||||| .|.|          .|.||||.||... | .| .|.    . . .|. .   ..                .    | .  |   
NTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF

---CLSKNPEERPT-VDQLLNMAIF
   .| |.||.|.|  .|.||  .|
GKRMLQKDPEKRITGWEQILNHPWF

Pkinase 87050.m00035.AA Pkinase 27-257 25 1.2e-44 159.01 Pfam 14-293 (293) Show / Hide
Range on Protein: 27-257
Range on HMM: 14-293/293
Sequence Identity: 25% (71 aa)

VVYLVYDPHYETHFALKVIPENRFRQ---------SEINLMNEIDDPSIVRMYNYEHYEGFIYILYEFCQA-----SLYSIIK--QKNYL--DGDNLIRY
.||. ..  ..  .|.|.|.  . .          ||| .|.... | |||.| . .... ||.  |.|.      .|...|.  ... .  . . ...|
CVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFY

SCGILKAIQACQNNKIAHLDIKPENILLDDYDRI----KICDFGLSIK--YENKDTELHYGGSIPFIAPEILDMKPYNPFKADIWSIGVTFFVMATGFFP
   ||.... | ...| | |.||||||.|. . |    |||||||. .  | |.    .. |.....|||..   .| . |.|.||.|.... |..| .|
MYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP

WIGA------DETELCQNTLHKKPQLELIRN---------------------HEFQKVIGCCLSKNPEERPTVDQLLNMAIF
. |.      |. .. ........  .                          |....| .|| |.|..||| .|.|.   |
FPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 87050.m00035.AA CAMKL 52-253 28 2.3e-42 132.93 In-house 60-293 (297) Show / Hide
Range on Protein: 52-253
Range on HMM: 60-293/297
Sequence Identity: 28% (68 aa)

QSEINLMNEID---DPSIVRMYNYEHYEGF------IYILYEFCQAS---LYSIIKQKNY----LDGDNLIRYSCGILKAIQACQNNKIAHLDIKPENIL
. ||..|  ..    | |...|     . .      ||.  | |.     |.  |... .    .. .   || . |. |.. | ...|.| ||||||||
RREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENIL

LDDYD--RIKICDFGLSIKYEN-----KDTELHYGGSIPFIAPEILDM--KPYNPFKADIWSIGVTFFVMATGFFPWIGAD---------ETELCQNTLH
||. .   |||.|||.|..|..      ..     || |. ||||.    |||. .|.||||.||. ..| .| .|. ...         . .. .... 
LDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-

KKPQLELIRNHEFQKVIGCCLSKNPEERPTVDQLLN
..|   .    . .  |   | .|||.|||..|..|
YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

Kinase 87050.m00035.AA Ciliate-E2-Unclassified 57-257 24 3.9e-41 140.45 In-house 70-352 (352) Show / Hide
Range on Protein: 57-257
Range on HMM: 70-352/352
Sequence Identity: 24% (70 aa)

LMNE----IDDPSIVRMYNYEHYEGFIYILYEFC------------------QASLYSIIKQKNYLDGDNLI-----RYSCGILKAI-QACQNNKIAHLD
.|..    ...| ||.|. ..  .  ||| .|.|                  .  |.  .||.. ..  . .     .|   ||... . ...|.| | |
IMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRD

IKPENILLDDYD---RIKICDFGLSIKYEN----------------KDTELHYGGSIPFI----APEILDMKPYNP---FKADIWSIGVTFFVMATGFFP
|||||||.|.     .|||.|||.|.||..                ..   .  |.. ..    |||.|. . |.    .|.|||| || .. | .| .|
IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP

WIGADETE----------------LCQNTLHKKPQLEL--------IRNHEFQKVIG----CCLSKNPEERPTVDQLLNMAIF
  . ....                | || . |..|           . . | .  |     ..| |||..|.| .|.||  .|
FYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 87050.m00035.AA STE 40-257 22 5.7e-37 128.11 In-house 42-359 (359) Show / Hide
Range on Protein: 40-257
Range on HMM: 42-359/359
Sequence Identity: 22% (74 aa)

FALKVIP----------------------ENRFRQSEINLMNEID--DPSIVRMYNYEHYEG-------FIYILYEFCQA-SLYSIIKQK-NYLDG----
.| |...                      |    . ||..|.. .   | ||. | .. .||        ..|  |.. . || .|||.|   ...    
MAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHN

--------DNLI-RYSCGILKA-IQACQNNKIAHLDIKPENILLDDYDRIKICDFGLSIKYENK-------------DTEL----HYGGSIPFIAPEILD
         ..| .. . |||.  .   ...| | |||| ||||     .|.||||.. . ...             .|      .  |.  . |||...
RQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQ

M------KPYNPFKADIWSIGVTFFVMATGFFPWIG-ADETELCQNTLH---------------KKPQLELIRN-------------------HEFQKVI
       |.|. .|.||||.| |   ||||  ||    .   . . .                 . |.|.                        ||.  |
QNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFI

GCCLSKNPEERPTVDQLLN--MAIF
  || |.|..|||..|||.     .
NKCLQKDPNKRPTASQLLKSEHPFI

Kinase 87050.m00035.AA ULK 39-257 22 7.1e-36 124.8 In-house 30-324 (324) Show / Hide
Range on Protein: 39-257
Range on HMM: 30-324/324
Sequence Identity: 22% (67 aa)

HFALKVIP-------ENR--------FRQSEINLMNEID---DPS--IVRMYNYEHYE--GFIYILYEFCQA-SLYSIIKQKNY---------LDGDNLI
..| |.|.       .|.        . ..||..| ...    |   ||..| .       .||| .|.|.   | ..||....         |  .  |
YVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAI

RYSCGILKAIQACQNNKIAHLDIKPENILLDDYD------------RIKICDFGLSIKYENKDTELHYG----------GSIPFIAPEILD----MKPYN
 .   |. . .. ....| | ||||.|||. . .            ..||.|||.. . .| . |              |.  . ||.||      |||.
QFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYY

PFKADIWSIGVTFFVMATGFFP---WIGADET----EL----------CQNTLHKKPQ--LELIRNHEFQKVIGCCLSKNPEERPTVDQLLNMAIF
 .|.||||.|. |. | .|  |   |   |.     .|           .|.  ..|    . ..  |..  | ..| .....| . ....|. .|
DYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF

Kinase 87050.m00035.AA ULK 40-257 22 2.8e-35 120.65 In-house 31-329 (329) Show / Hide
Range on Protein: 40-257
Range on HMM: 31-329/329
Sequence Identity: 22% (67 aa)

FALKVIP---ENRFR------------QSEINLMNEIDDPS--------IVRMYNYEHYEGF--IYILYEFCQA-SLYSIIKQKNY----------LDGD
.| |.|.   .|..             ..|| .| ....|         ||..| .     .  ||| .|.|.   | ..||....          |  .
VACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQ

NLIRYSCGILKAIQACQNNKIAHLDIKPENILLDDYD------------RIKICDFGLSIKYE-N---KDTELHYG------GSIPFIAPEILD----MK
  | . . || . .. . ..| | ||||.|||... .            ..||.|||.. . . .   .. .. .       |.  . ||.||      |
EAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQK

PYNPFKADIWSIGVTFFVMATGFFP---WIGADET-ELCQNTLHK---------KPQLELI-------RNHEFQKVIGCCLSKNPEERPTVDQLLNMAIF
||. .|.||||.|. |. | .|  |   |   |.    .|. . .         | .|.         .  |..  | ..| .....| . ..|.|. .|
PYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF





Kinase 87050.m00035.AA MARK 112-253 39 2.2e-34 109.92 In-house 113-258 (262) Show / Hide
Range on Protein: 112-253
Range on HMM: 113-258/262
Sequence Identity: 39% (57 aa)

ILKAIQACQNNKIAHLDIKPENILLDDYD--RIKICDFGLSIKYENKDTELHYGGSIPFIAPEILDMKPYNPFKADIWSIGVTFFVMATGFFPWIGAD--
|. |.. | .. |.| ||||||||.|.     |||.|||.||. ..        |. |. ||||.  |||. .|.|||| ||  ..| .| ||. |..  
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQD

ETELCQNTLHKKPQLELIRNHEFQKVIGCCLSKNPEERPTVDQLLN
. || .. |. |..      .| .. |   |  |||||||......
YKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMK

Kinase 87050.m00035.AA CMGC 27-202 17 1.5e-26 83.5 In-house 14-344 (513) Show / Hide
Range on Protein: 27-202
Range on HMM: 14-344/513
Sequence Identity: 17% (59 aa)

VVYLVYDPH--------------YETHFALKVIP---ENRFRQ-------------SEINLMNEI-----------------DDPSIVRMYNYEHYEG--
|||  .| .              .. . |.| |    . .  .              || .. ..                 ... ||..|.. ....  
VVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSD

---------------FIYILYEFCQASLYSIIKQKN---------YLDGDN------------LIRYS------CGILKAIQ--ACQNNK--IAHLDIKP
                .|.  |... .|| .||...         .|.                  ..        ||...    |  ..  | | |.||
GNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKP

ENILLDD--------------------YDRIKICDFGLSIKYENKDTE----------------------LHYGGSIPFIAPEILD-MKPYN--------
||||...                     .|.|||||||. .|.. . .                       ||  .    |||||  .| |.        
ENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHY

PFKADIWSIGVTFFVMATG----------FFP
  . |.||.|  |. | ||          .||
TTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFP

Kinase 87050.m00035.AA PLK1 54-257 28 9e-26 81.47 In-house 49-253 (253) Show / Hide
Range on Protein: 54-257
Range on HMM: 49-253/253
Sequence Identity: 28% (59 aa)

EINLMNEIDDPSIVRMYNYEHYEGFIYILYEFCQ-ASLYSIIKQKNYLDGDNLIRYSCGILKAIQACQNNKIAHLDIKPENILLDDYDRIKICDFGLSIK
||..  ... . ||.....   . ..||. | |.  ||  . |..  .       |   |....|  .|||| | |.|  |. |.|  ..|| ||||  |
EIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATK

YENK-DTELHYGGSIPFIAPEILDMKPYNPFKADIWSIGVTFFVMATGFFPWIGADETELCQNTLHKKPQLELIRNHEFQKVIGCCLSKNPEERPTVDQL
 |.. .     .|   .||||.|  |    |  ||||||  ....  |  |.      |  .   . . ..  . ..  ...|   | ..|..|||..|.
CEYDGERKKTLCGTPNYIAPEVLNKKGHS-FEVDIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQV

LNMAIF
||.  |
LNDEFF

TyrKc 87050.m00035.AA TyrKc 14-255 19 2.2e-10 -54.89 SMART 1-280 (280) Show / Hide
Range on Protein: 14-255
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

IIIKDIVDADEHMVVYL-VYDPHYETHFALKVIPENRFRQ---SEINLMNEI--DDPSIVRMYNYEHYE-------GFIYILYEFCQA-SLYSIIKQKNY
|  ...    .  .||. ...    .  | |.. |.  |.   .|...| ..  . | |||.| .   .       . ..|. |..   .| . .. .  
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LDGDNLIRYSCGILKAIQACQNNKIAHLDIKPENILLDDYDRIKICDFGLSIKYENKD-----TELHY-----GGS--IPF--IAPEILDMKPYNPFKA
 |  . |. ..  | .  .    ... | |.   |.|...  ..||.||||| . ...|     ..        ||   .|    ||| .. . .. .| 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS

DIWSIGVTFF-VMATGFFPWIG-----ADETELCQNTLHK----KPQL--ELI----RNHEFQKVIGCCLSKNPEERPTVDQLLNMA
|.|| ||. . ..  |  |. |      . .|. ..  .     .|.   . .       |  ... .|   .||.|||  ..    
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 87050.m00035.AA CMGC 237-257 33 0.006425 4.39 In-house 493-513 (513) Show / Hide
Range on Protein: 237-257
Range on HMM: 493-513/513
Sequence Identity: 33% (7 aa)

CLSKNPEERPTVDQLLNMAIF
.|  .|..|.|..| |..  |
MLQYDPDKRITAEQALQHPYF

Kinase 87050.m00035.AA MARK 27-70 21 0.024717 3.63 In-house 14-65 (262) Show / Hide
Range on Protein: 27-70
Range on HMM: 14-65/262
Sequence Identity: 21% (11 aa)

VVYLVYDPHYETHFALKVIP-------EN-RFRQSEINLMNEIDDPSIVRMY
.|.|. . |.....|.|...       .. .  ..||..|  .| | |....
KVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLF