Gene 81982.m00121 (T.vaginalis)

81982.m00121

Species: T.vaginalis
Alias: TvagK0941, 81982.m00121
External Links:
Annotation:

Classification

Group: CMGC
Family: CLK

Sequence

Name Sequence Type Origin Length Description Download
81982.m00121.AA Protein None 340 None Fasta, JSON
81982.m00121.kin_dom Protein Kinase Domain None 299 None Fasta, JSON

Protein domain

Protein domains of 81982.m00121.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 81982.m00121.AA S_TKc 24-336 19 6e-39 136.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-336
Range on HMM: 1-231/231
Sequence Identity: 19% (65 aa)

YRVVSEYHPGISSNVYRCVNIKNNTEVAIKCFRNSEMSSTHFMKSIALYKNLQKMKDFNEHFCDFFAWFYFDEHPCIVIERYGP---SLYDVMKFNHFRG
|... .   |  . ||.|...| . .||||. .       |... |.. |.        .. . .. .|.  .| ..| |  .    .|.|..| .  .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----WRLETIRQVLTQTIQALILLRNAGKLHGDIKLENILIDPNIRVSESDIFLNTGKPQPKYVQVKLIDMETTHNYYQWGSGTITTIYYRAPETILGIP
        ..| .. |...||  . . | .| |.| ||||.|                      ..|..|      .    .  . | .|.||| .   .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------HIKICDFGLARQL----TTFCGTPWYMAPEVL---G

WGR-EVDIWSLGCLALEMCVGKIYFAYSDLSSFLFAIQHLIGPFPDKMINDCTIPMFKRLFENGILNPKYIGQKDYDEINTKIPLYRIDMDHDLKDLIMN
.|. ..|.||.||.  ||..|.  |        .... ..||                                                ....||.|..
YGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------------------------------------------SPEAKDFIRK

MLSIDPLARPTLDDLLL-------HPFL
.|  ||  |||  ..|        ||..
CLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81982.m00121.AA CMGC 24-336 15 6.7e-37 118.14 In-house 1-513 (513) Show / Hide 
Range on Protein: 24-336
Range on HMM: 1-513/513
Sequence Identity: 15% (83 aa)

YRVVSEYHPGISSNVYRCVN--------------IKNNTEVAIKCFRNSEMSSTHFM-------KSIALYKNLQKMKDFN-----------------EH-
| ...    |  ..||.|..              ...| .|||| ..| .   ..         ..|  .  .. .| .|                 .. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

FCDFFAWFYFDE-----------------HPCIVIERYGPSLYDVMKFNHF-----RGWRL-------------ETIRQVL------TQTIQALI--LLR
    . .||...                 | ..| |  . .||...| |.|     |.  |             ..|.  .       | ...|    . 
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

NAG--KLHGDIKLENILIDPNIRV-----------SESDIFLNTGKPQPKYVQVKLIDM---ETTHNYYQW---------------------GSGTITTI
 ..   .| |.| |||||..| ..           ..            |  ..|..|      .|..                         .  . | 
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPC----------QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTR

YYRAPETILGIP----------WGREVDIWSLGCLALEMCVG--------KIYFA-----------YSDLSSFLFAIQHLIGPFPDKMIND---------
.||||| .|| .          .. ..|.||.||   ||  |        |. |            ...    || |  ..|... .||.          
WYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCK

-CT--------------------------IPMFKRLFENGILNPKYIGQKDYDEINTKIPL----------------------------YRIDMDHDLKD
                             .. | |.. .  .. . .  |.  ..  ..|                              | ..|... |
HEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAID

LIMNMLSIDPLARPTLDDLLLHPFL
|...|| .||  |.| .. | ||..
LLKKMLQYDPDKRITAEQALQHPYF
Kinase 81982.m00121.AA Ciliate-E2 38-336 16 1.5e-27 91.63 In-house 15-365 (365) Show / Hide 
Range on Protein: 38-336
Range on HMM: 15-365/365
Sequence Identity: 16% (70 aa)

VYRCVNIKNNTEVAIKCFRNSE----------------MSSTHFMKSIALYKNLQKM-----------------KDFNEHFCDFFAWFY--FDEHPCIVI
||.| ..|.. ..|||...                   | . .  . ... . .. |                 .. . . . .. .|.   |..  .| 
VYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVM

ERY-GPSLYDVMKFN-HFRGWR--------LETIRQVLTQTIQ---------------ALILLRNAG-KLHGDIKLENILIDPNIRVSESDIFLNTGKPQ
| . | .|.| .| | ..|.          .. |... .| .|               ||  | . .  .| |||.||||.                   
EYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-------------------

PKYVQVKLIDMET----------------THNYYQWG---SGTIT----------------TIYYRAPETILGIP---------WGREVDIWSLGCLALE
     .|.||. .                  .| . .   |.|..                | .| ||| . | .         .. ..||||||..  |
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

MCVGKIYFAYSDLSSFLFAIQHLIGPFPDKMINDCTIPMFKRLFENGILNPKYIGQKDYDEINTKIPLYR------------------IDMDHDLKDLIM
|. ||  |                                                  ...|  .   ..                   . . . |||| 
MLFGKPPF--------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIK

N----MLSIDPLARPT-LDDLLLHPFL
.    ||  ||  |.|  ...| ||..
KFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81982.m00121.AA Ciliate-E2-Unclassified 24-336 17 3.7e-22 73.69 In-house 1-352 (352) Show / Hide 
Range on Protein: 24-336
Range on HMM: 1-352/352
Sequence Identity: 17% (69 aa)

YRVVSEYHPGISSNVYRCVNIKNNTEV--------AIKCFRNSEMSSTHFMKSIALYKNLQKMKDFNE--------------HFCDFFAWFYF--DEHPC
|...     |  . ||.|...|.. ..        .... ... |..   .. ...  | .|. ....              | .     ..|  .....
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

IVIERY-GPSLYDVMKFNHF---------------RGWRLETIR-----QVLTQTIQAL-ILLRNAGKLHGDIKLENILIDPNIRVSESDIFLNTGKPQP
|| |   | .| . .| ...               .    . ..     . . | .|.|  | .. . .| |||.||||.| | .               
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK---------------

KYVQVKLIDMETTHNYYQW------------------GSGTITTIYYR----APETILGIPWGRE----VDIWSLGCLALEMCVGKIYFAYSDLSSFLFA
   ..|.||     .| |                    . .. |..|     ||| . |   . .    .||||||... ||. |.  | . .  .  . 
-NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQL

IQHLIGP-----FPDKMINDCTIPMFKRLFENGILNPKYIGQKDYDEINTKIPLYRIDMDHD--LKDLIM----NMLSIDPLARPTLDDLLLHPFL
|.  |          . |... |  .|  . .                        |... .   ||.|      ||  .|  |.|....| ||..
ITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQ------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81982.m00121.AA DYRK 205-336 26 8.2e-20 70.91 In-house 169-320 (320) Show / Hide 
Range on Protein: 205-336
Range on HMM: 169-320/320
Sequence Identity: 26% (41 aa)

YYRAPETILGIPWGREVDIWSLGCLALEMCVGKIYFAYSDLSSFLFAIQHLIGPFPDKMINDCTIPMFKRLFENGILNPKYIGQKDYDEINT------K-
.||||| |||.| . ..|.|||||   |.  |.. |. ..    |  |. ..|..| .||.  . .  .. |..    ..|  ... .. |.        
FYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC----FMYCECDEWTKQNKITDHYMTP

------------------IPLYRIDMDHDLKDLIMNMLSIDPLARPTLDDLLLHPFL
                  .|. .   ||..||.|. .| .||  |.|  . | ||..
KCHPTKRGQRRPPGRRNWDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase 81982.m00121.AA DYRK1 92-265 31 2.9e-16 53.17 In-house 70-228 (321) Show / Hide 
Range on Protein: 92-265
Range on HMM: 70-228/321
Sequence Identity: 31% (55 aa)

FYFDEHPCIVIERYGPSLYDVMKFNHFRGWRLETIRQVLTQTIQALILLR--NAGKLHGDIKLENILIDPNIRVSESDIFLNTGKPQPKYVQVKLIDMET
| | .| |.|.|     |||...  ||||  |  .|.   | ..||. .       .| |.| ||||.                   ||  ..|.||   
FMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLC-----------------NPKRSAIKIIDFGS

THNYYQWGSGTITTIYYRAPETILGIPWGREVDIWSLGCLALEMCVGKIYFAYSDLSSFLFAIQHLIGPFPDKMIN
  .  |     |   .||.|| .|||..  ..|.|||||.  || .|   |. |.    .  |   .|  |..||.
SCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMID
Kinase 81982.m00121.AA CLK 89-157 34 1.6e-14 39.24 In-house 72-147 (350) Show / Hide 
Range on Protein: 89-157
Range on HMM: 72-147/350
Sequence Identity: 34% (26 aa)

FAWFYF-DEHPCIVIERYGPSLYDVMKFNH------FRGWRLETIRQVLTQTIQALILLRNAGKLHGDIKLENILI
..|| .   | ||| |.|| |.||.|| |.      ... ....||.   | ..|.  |   .  | | | |||..
NDWFDYGHGHICIVFELYGLSIYDFMKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICF
Kinase 81982.m00121.AA DYRK2 203-241 43 3.2e-14 42.33 In-house 165-203 (318) Show / Hide 
Range on Protein: 203-241
Range on HMM: 165-203/318
Sequence Identity: 43% (17 aa)

TIYYRAPETILGIPWGREVDIWSLGCLALEMCVGKIYFA
. .||||| |||.. | ..|.||.|| . |.  |.. |.
SRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFP
Kinase 81982.m00121.AA HIPK 50-159 33 3.5e-13 37.38 In-house 27-137 (329) Show / Hide 
Range on Protein: 50-159
Range on HMM: 27-137/329
Sequence Identity: 33% (37 aa)

VAIKCFRNSEMSSTHFMKSIALYKNLQKMKDFNEHFCDFFAWFYFDEHPCIVIERYGPSLYDVMKFNHFRGWRLETIRQVLTQTIQALILLRNAGKLHGD
||||  .|    .      . . . |..    . ||  ..  |   .| |.| |     ||| .| |.|    |  || .| | . ||. |.. | .| |
VAIKILKNHPYYARQGQIEVSILHCLSQENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLPLKHIRPILQQVLTALMKLKELGLIHAD

IKLENI-LIDP
.| ||| |.||
LKPENIMLVDP
Kinase 81982.m00121.AA DYRK 92-157 36 7.7e-13 44.56 In-house 70-137 (320) Show / Hide 
Range on Protein: 92-157
Range on HMM: 70-137/320
Sequence Identity: 36% (25 aa)

FYFDEHPCIVIERYGPSLYDVMKFNHFRGW-RLETIRQVLTQTIQALILLRNA-GKLHGDIKLENILI
||. .| ||| | .  .||...|.|||.|   |. .|... |  ..| .| .    .|.|.| |||..
FYHRNHLCIVFELLSMNLYEFLKNNHFQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIML
Kinase 81982.m00121.AA DYRK2 92-156 40 8e-12 34.4 In-house 70-134 (318) Show / Hide 
Range on Protein: 92-156
Range on HMM: 70-134/318
Sequence Identity: 40% (26 aa)

FYFDEHPCIVIERYGPSLYDVMKFNHFRGWRLETIRQVLTQTIQALILLRNAGKLHGDIKLENIL
|||  | ||. | .. .||. .| ||| |  |. .|    . .|.| .|.     |.| | ||||
FYFRNHHCITFELLSMNLYEYIKKNHFQGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENIL
Kinase 81982.m00121.AA Pkinase 203-240 46 2.1e-11 41.43 Pfam 174-212 (293) Show / Hide 
Range on Protein: 203-240
Range on HMM: 174-212/293
Sequence Identity: 46% (18 aa)

TIYYRAPETIL-GIPWGREVDIWSLGCLALEMCVGKIYF
|..|.||| |. | ..|..||.||.||.  ||. |.  |
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF
Kinase 81982.m00121.AA CLK 206-264 40 4.2e-10 25.74 In-house 213-272 (350) Show / Hide 
Range on Protein: 206-264
Range on HMM: 213-272/350
Sequence Identity: 40% (24 aa)

YRAPETILGIPWGREVDIWSLGCLALEMCVGKIYFAYSDLSSFLFAIQHLIG-PFPDKMI
||||| ||| .|    |.|| ||   |  .|   |   | .  |  .. . | |.|  ||
YRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMI
Kinase 81982.m00121.AA CLK 307-336 50 9.6e-10 24.64 In-house 321-350 (350) Show / Hide 
Range on Protein: 307-336
Range on HMM: 321-350/350
Sequence Identity: 50% (15 aa)

HDLKDLIMNMLSIDPLARPTLDDLLLHPFL
. | ||| .|| .|| .|.|..| | ||| 
RQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase 81982.m00121.AA PRP4 24-157 31 3.2e-09 29.99 In-house 1-139 (320) Show / Hide 
Range on Protein: 24-157
Range on HMM: 1-139/320
Sequence Identity: 31% (44 aa)

YRVVSEYHPGISSNVYRCV-NIKNNTEVAIKCFRNSEMSSTHFMKSIALYKNLQKM---KDFNEHFCDFFAWFYFDEHPCIVIERYGPSLYDVMK-FNHF
|||..    |. ||| ||  . . | .||||  || |.     .. .   . |      |.   |    |  |..  | |.| |    .| .|.| .   
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

RGWRLETIRQVLTQTIQALILLRNAGKLHGDIKLENILI
 |  |. .|    |   || .| . . || |||  |||.
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILV
Kinase 81982.m00121.AA Pkinase 38-186 20 3.2e-09 33.71 Pfam 15-155 (293) Show / Hide 
Range on Protein: 38-186
Range on HMM: 15-155/293
Sequence Identity: 20% (34 aa)

VYRCVNIKNNTEVAIKCFRNSEMSSTHFMK-----SIALYKNLQKMKDFNEHFCDFFAWFYFDEHPCIVIERYGP-----SLYDVMK---FNHFRGWRLE
||.|...... .||.|... .. .|   .       |.. |.|.      .. . .. ||. . |...| |  .      .|.|...    . |     .
VYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-FSEW

TIRQVLTQTIQALILLRNAGKLHGDIKLENILIDPNIRVSESDIFLNTGKPQPKYVQVKLID
... ...|....|  . . | .| |.|.|||||| |  ...                ||..|
ECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA---------------CVKICD
Kinase 81982.m00121.AA HIPK 205-228 66 6.5e-09 23.7 In-house 168-191 (329) Show / Hide 
Range on Protein: 205-228
Range on HMM: 168-191/329
Sequence Identity: 66% (16 aa)

YYRAPETILGIPWGREVDIWSLGC
|||||| |||.|   ..|.|||||
YYRAPEIILGLPFCENHDMWSLGC
Kinase 81982.m00121.AA PRP4 205-240 50 6.8e-08 25.07 In-house 170-205 (320) Show / Hide 
Range on Protein: 205-240
Range on HMM: 170-205/320
Sequence Identity: 50% (18 aa)

YYRAPETILGIPWGREVDIWSLGCLALEMCVGKIYF
.||||| |.|.|    .|.|| ||   |.  ||| |
FYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMF
Kinase 81982.m00121.AA STE 208-237 41 9.4e-08 23.59 In-house 230-265 (359) Show / Hide 
Range on Protein: 208-237
Range on HMM: 230-265/359
Sequence Identity: 41% (15 aa)

APETILG------IPWGREVDIWSLGCLALEMCVGK
||| |..       . .. .|||||||...||. ||
APEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase 81982.m00121.AA STE 308-336 45 2.4e-07 22.12 In-house 329-359 (359) Show / Hide 
Range on Protein: 308-336
Range on HMM: 329-359/359
Sequence Identity: 45% (14 aa)

DLKDLIMNMLSIDPLARPTLDDLLL--HPFL
..|| | . | .||  ||| ..||   |||.
EFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81982.m00121.AA STE 124-186 23 3.2e-07 21.7 In-house 151-190 (359) Show / Hide 
Range on Protein: 124-186
Range on HMM: 151-190/359
Sequence Identity: 23% (15 aa)

ETIRQVLTQTIQA-LILLRNAGKLHGDIKLENILIDPNIRVSESDIFLNTGKPQPKYVQVKLID
. |. .. |.... | .| . .. | |||  |||.                        |||.|
SQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------------------------VKLCD
Kinase 81982.m00121.AA Pkinase 308-336 41 7e-06 21.78 Pfam 265-293 (293) Show / Hide 
Range on Protein: 308-336
Range on HMM: 265-293/293
Sequence Identity: 41% (12 aa)

DLKDLIMNMLSIDPLARPTLDDLLLHPFL
..||.| ..|  ||  ||| ...| ||..
ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81982.m00121.AA PRP4 307-336 43 2.9e-05 15.31 In-house 291-320 (320) Show / Hide 
Range on Protein: 307-336
Range on HMM: 291-320/320
Sequence Identity: 43% (13 aa)

HDLKDLIMNMLSIDPLARPTLDDLLLHPFL
| .|||. ..|  ||  | |. . | |||.
HQFKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase 81982.m00121.AA TyrKc 34-336 14 0.00093 -161.87 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-336
Range on HMM: 1-280/280
Sequence Identity: 14% (50 aa)

ISSN----------VYRCVNIKNNTEVAIKCFRNSEMSSTHFMKSIALYKNLQKMKDF---NEHFCDFFAWFYFD-------EHPCIVIE--RYGPSLYD
|. .          ||... .   ..||.|. ...           .... .. |. .   ...   ...    .       | ..|| |   .| .| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG-DLKD

VMKFNHFRGWRLETIRQVLTQTIQA---LILLRNAGKLHGDIKLENILIDPNIRVSESDIFLNTGKPQPKYVQVKL------IDMETT------HNYYQW
  . .. .     . .. |   .|.      |   .  | |.   |.|.. |                    .||        | .        . ||  
YLRKHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------TVKISDFGLSRDIYDDDQQGESKDYYRK

GS--GTI--TTIYYRAPETILGIPWGREVDIWSLGCLALEMC-VGKIYFAY-----SDLSSFLFAIQHLIGPFPDKMINDCTIPMFKRLFENGILNPKYI
 .  |.     |   |||.|       . |.|| | .  |..  |.           . .  .  ...  |  .... ||.  ||               
KEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ--GYRMPQPPNDY--PMS--------------

GQKDYDEINTKIPLYRIDMDHDLKDLIMNMLSIDPLARPTLDDLLLHPFL
              .   .  .. ...      ||  |||  ..  | ..
--------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 81982.m00121.AA DYRK1 310-336 48 0.001262 8.04 In-house 295-321 (321) Show / Hide 
Range on Protein: 310-336
Range on HMM: 295-321/321
Sequence Identity: 48% (13 aa)

KDLIMNMLSIDPLARPTLDDLLLHPFL
||||  ||  || .| |  . | |.|.
KDLIKRMLQYDPKQRITPYYALQHSFF
Kinase 81982.m00121.AA DYRK2 306-336 32 0.171078 0.24 In-house 288-318 (318) Show / Hide 
Range on Protein: 306-336
Range on HMM: 288-318/318
Sequence Identity: 32% (10 aa)

DHDLKDLIMNMLSIDPLARPTLDDLLLHPFL
| .. | |.  .  ||  | | .. | ||..
DENFIDFIKRCFEWDPSERMTPSQALKHPWI