Gene 90210.m00287 (T.vaginalis)

90210.m00287

Species: T.vaginalis
Alias: 90210.m00287, TvagK0896
External Links:
Annotation:

Classification

Group: Other
Family: Uni1

Sequence

Name Sequence Type Origin Length Description Download
90210.m00287.AA Protein None 1232 None Fasta, JSON
90210.m00287.kin_dom Protein Kinase Domain None 281 None Fasta, JSON

Protein domain

Protein domains of 90210.m00287.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 90210.m00287.AA S_TKc 936-1216 19 8.5e-27 96.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 936-1216
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

YANGKHIASGAFGVVMKAPGKD--KPVAVKILQKSLNEFENPHLFEVYSEVSILDTCKGDRRVTQLVDFGCTKNSYYIVMEFYPF---TLKAWRKSVNEK
|  ...| .||||.|.|.  |.  . ||.||.              ...|..||    .   . .| |.  . ...|.|||. .    .|.   |. . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

P-----PLNTMLRVYREFLKACTVLTDRYINHFDIKCDNVMLDFDGMPALADFGESMCYKRESNSYTLLNKGTEWIKSPEMLSIALTSTATDPKFDRRKK
.     |  .  .. .. ..|   . .. | | |.| .|..||      ..||| .  .            || |  .||.|                  
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL------------------

VGAGP-PSDIWSIGCLFFELLTGHFLFATTDWSYFYTRVTGERPVLDDVDRNELKELGCNDNVEIFLDFVLKRKEIQRPSLEQVISKY-----DELF
 | |. ..|.||.||...|.|.|  .|   .    . ..                     . .  |..  |..   .||.  ..         .. |
-GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90210.m00287.AA Pkinase 1059-1151 26 4e-11 40.43 Pfam 133-212 (293) Show / Hide 
Range on Protein: 1059-1151
Range on HMM: 133-212/293
Sequence Identity: 26% (26 aa)

DIKCDNVMLDFDGMP----ALADFGESMCYKRESNSYTLLNKGTEWIKSPEMLSIALTSTATDPKFDRRKKVGAGPPSDIWSIGCLFFELLTGHFLF
|.| .|...| .| .     ..||| . ...  .|| .    || |  .|| .                .  . ||..|.||.||...|.|.|...|
DLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---------------GGQYYGPKVDMWSCGCILYEMLCGRPPF
Kinase 90210.m00287.AA Ciliate-E2 936-1209 14 6.2e-11 33.76 In-house 1-360 (365) Show / Hide 
Range on Protein: 936-1209
Range on HMM: 1-360/365
Sequence Identity: 14% (57 aa)

YANGKHIASGAFGVVMKAPGKDKPV------------------AVKILQKSLNEFENPHLFEVYSEVSIL--DTCKGDRR---------------VTQLV
|   | | .|.||.| |.  . ..                    ||| .. .. ...  .... .| .|.    | .  .               . ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FY-KKINEKNILEQLNHPNIIKMY

DFGC--TKNSYYIVMEFYPF-TLKA-----WRKSVNE-----KPPLNTMLRVYREFLK---------------ACTVLTDRY-INHFDIKCDNVMLDFDG
..    ..|..|.|||..   .|.      . |. .|     .. .. .... .. |.               |   |  .  | | ||| .|...    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

MPALADFGESMCYKRE-------SNSYTLLNKG------------------------TEWIKSPEMLSIALTSTATDPKFDRRKKVGAGPPSDIWSIGCL
 . ..||| |  |. .       . .. ... .                        |   ..||.|.    ..         |. | .  .||||.|..
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ-------QKQKGYDYKCDIWSLGVI

FFELLTGHFLFATTDWSYFYTRVTGERPVLDDVDRNELKELGCNDNVEIFL-----------------------DFVLK-------RKEIQRPS-LEQVI
..|.|.| . |                         . . . |. .   .                        |.  |       ... .|..  ||..
LYEMLFGKPPF-------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL
Kinase 90210.m00287.AA SRPK 1129-1151 56 2.8e-10 21.1 In-house 430-452 (554) Show / Hide 
Range on Protein: 1129-1151
Range on HMM: 430-452/554
Sequence Identity: 56% (13 aa)

GPPSDIWSIGCLFFELLTGHFLF
..| ||||  |. |||.|| .||
NTPADIWSTACMAFELATGDYLF
Kinase 90210.m00287.AA AGC 1103-1151 29 1.6e-09 19.25 In-house 275-305 (395) Show / Hide 
Range on Protein: 1103-1151
Range on HMM: 275-305/395
Sequence Identity: 29% (15 aa)

SPEMLSIALTSTATDPKFDRRKKVGAGPPSDIWS--IGCLFFELLTGHFLF
.||.|                     |.. |.||   |||..|.|||.  |
APEIL--------------------YGKACDWWSFGLGCLMYEMLTGYPPF
Kinase 90210.m00287.AA Ciliate-A9 936-967 33 2.1e-09 17.65 In-house 1-36 (392) Show / Hide 
Range on Protein: 936-967
Range on HMM: 1-36/392
Sequence Identity: 33% (12 aa)

YANGKHIASGAFGVVMKAPGKD----KPVAVKILQK
. ..| | .||||.| ..  .     . .|||. ||
FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVKVIQK
Kinase 90210.m00287.AA CAMK 941-1015 15 9.6e-09 23.55 In-house 1-141 (425) Show / Hide 
Range on Protein: 941-1015
Range on HMM: 1-141/425
Sequence Identity: 15% (22 aa)

HIASGAFGVVMKAPGKDKP--------------VAVKILQKS-LNEFE----------------------NPHLFE-VYSEVSILDTCKG------DRRV
 . .|.||.| ..  |  .              ||.||. |. | . .                      .|.  . |..|..|. ...|       . .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TQLVD--------------------FGCTKNSYYIVM---EF
 .| .                    |  ... .|.||   |.
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEY
Kinase 90210.m00287.AA TyrKc 936-1212 16 3.5e-08 -90.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 936-1212
Range on HMM: 1-280/280
Sequence Identity: 16% (51 aa)

YANGKHIASGAFGVVMKAPGKDKPVAVKILQKSLNEFENPHLFEVYSEVSILDTC-KGDRRVTQLVDFGCTK-------NSYYIVMEFYPF-TLKAWRKS
   || . .||||.|.|.  |  .|||| |...        . . ..| .|.    .    . .|.    ..         ..||||. |   ||   ..
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

VNEKPPLNTMLRVYREFLKACTVLTDRYINHFDIKCDNVMLDFDGMPALADFGESMCYKRESN-------SYTLLNK--GTE------WIKSPEMLSIAL
  .| .. ..|       . .  | .. . | |. . |.... ..    .|||  .. . ..        .|    .  |.       |  .|| .    
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFG--LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECINYGK

TSTATDPKFDRRKKVGAGPPSDIWSIGCLFFELLTGHFLFATTDWSY-----FYTRVTGERPVLDDVDRNELKELG-------CNDNVEIFLDFVLKRKE
 .|.                ||.|| | . .|..|    .  . ..         .    .  ... .| .  . .       | | .        ... 
FTTK----------------SDVWSFGVCMWEIFT----YGQQPYPGMIQQMMSNQEV--IEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDP

IQRPSLEQVISKY
 .||. ...... 
EDRPTFSEIHECF
Kinase 90210.m00287.AA CMGC 1129-1155 34 4.3e-08 21.72 In-house 313-347 (513) Show / Hide 
Range on Protein: 1129-1155
Range on HMM: 313-347/513
Sequence Identity: 34% (12 aa)

GPPSDIWSIGCLFFELLTG--------HFLFATTD
..| |.||.|| |.|..||        . || . .
TTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHS
Kinase 90210.m00287.AA ULK 936-1079 20 9.2e-08 23.68 In-house 1-183 (324) Show / Hide 
Range on Protein: 936-1079
Range on HMM: 1-183/324
Sequence Identity: 20% (38 aa)

YANGKHIASGAFG-VVMKAP----G-KDKPVAVKILQKS-LNEFENP-----HLFEVYSEVSILDTCK--GDRR--VTQLVDFGCTK--NSYYIVMEFYP
|   . . .|.|| .| |.     . ... ||.|. .|. .|...|       ..   .|..|. . |        . .| |.  |.  | .||.||. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

F-TLKAWRKSVNEKP--------PLNTMLRVYREFLKACTVLTDRYINHFDIKCDNVMLDFD------------GMPALADFG
  .|.   |  ...|        . .  . . . .. ..  | .. | | ||| .| ..  .            |   .||||
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG
Kinase 90210.m00287.AA Pkinase 936-1017 30 9.9e-08 28.42 Pfam 1-83 (293) Show / Hide 
Range on Protein: 936-1017
Range on HMM: 1-83/293
Sequence Identity: 30% (27 aa)

YANGKHIASGAFGVVMKAPGKDKP--VAVKILQKSLNEFENP----HLFEVYSEVSILDTCKGDRRVTQLVDFGCTKNSYYIVMEFYP
|  |. | ||.||.| |.  |. .  |||||. |. .. . .    .|    ||..|.  .. .  . .| |.  .|...|.|||. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRLNHPN-IVRLYDWFEDKDHIYMVMEYCE
Kinase 90210.m00287.AA CAMK 1057-1149 19 2.9e-07 18.7 In-house 202-332 (425) Show / Hide 
Range on Protein: 1057-1149
Range on HMM: 202-332/425
Sequence Identity: 19% (27 aa)

HFDIKCDNVMLDFD-----------------GMPALADFGESMCYKRESNSYTLL-NKGTEWI----------------------KS-PEMLSI------
| |.|..|..|| .                 .   ..||| .  ... .|....  .|| | .                       . ||.|.       
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-MHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--ALTSTATDPKFDRRKKVGAGPPSDIWSIGCLFFELLTGHF
  | |           .| . ||..|.||.|.. . .|.|..
QNA-T---------DEEKPYYGPKCDMWSCGVILYIMLCGYP
Kinase 90210.m00287.AA STE 1057-1153 21 6.9e-07 20.49 In-house 175-270 (359) Show / Hide 
Range on Protein: 1057-1153
Range on HMM: 175-270/359
Sequence Identity: 21% (24 aa)

HFDIKCDNVMLDFDGMPALADFGESMCYKRE--------------SNS-YTLLNKGTEWIKSPEMLSIALTSTATDPKFDRRKKVGAGPPSDIWSIGCLF
| |||..|..|       |.||| . .   .              ...  .    ||    .||...   ..           . | .  .||||.||. 
HRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R---------DKGYDTKCDIWSLGCTI

FELLTGHFLFAT
 |..||.  ...
IEMATGKPPWHD
Kinase 90210.m00287.AA AGC 936-1018 22 2e-06 11.15 In-house 1-118 (395) Show / Hide 
Range on Protein: 936-1018
Range on HMM: 1-118/395
Sequence Identity: 22% (26 aa)

YANGKHIASGAFGVVMKAPGK--------DKPVAVKILQKSL-----NEFENPHLF-E--------VYSEVSILDTCKG---------DRRVTQ-LVDFG
.   |.|  |.|| |. .  |        .|  |.|.|.|.      .. .  |   |        | .|  || .|..            ... |    
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

CTKNS--YYIVMEFYP-F
 .|.    |.|||..| .
QDKDHTYLYFVMEYMPRY
Kinase 90210.m00287.AA GSK 1133-1152 50 2e-06 15.28 In-house 201-220 (328) Show / Hide 
Range on Protein: 1133-1152
Range on HMM: 201-220/328
Sequence Identity: 50% (10 aa)

DIWSIGCLFFELLTGHFLFA
|.||.|| ..|.|.|. ||.
DVWSCGCVMAEMLKGQPLFP
Kinase 90210.m00287.AA ULK 936-1079 19 4e-06 17.57 In-house 1-187 (329) Show / Hide 
Range on Protein: 936-1079
Range on HMM: 1-187/329
Sequence Identity: 19% (37 aa)

YANGKHIASGAFGVVMKA----PG--KDKPVAVKILQ---KSLNEFENP---HLFEVYSEVSILDTCK---GDRR----VTQLVDFGCTK--NSYYIVME
|   . . .|.||.| |.     .  ... ||.|...   .. .. |..    .. . .|. |. . |   .       . .| |.  |.  | .||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FYPF-TLK---AWRKSVNEKP------PLNTMLRVYREFLKACTVLTDRYINHFDIKCDNVMLDFD------------GMPALADFG
. .  .|.     .|  .|.       . .  . . . .| ..  | .. | | ||| .|.... .            |   .||||
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG
Kinase 90210.m00287.AA STE 936-1017 13 5e-06 17.34 In-house 1-120 (359) Show / Hide 
Range on Protein: 936-1017
Range on HMM: 1-120/359
Sequence Identity: 13% (16 aa)

YANGKHIASGAFGVVMKA----PG-------------KDKPVAVKILQKSLNEFENPH--------------LFEVYSEVSILDTCKG-DRRVTQLVDFG
. . . | .||||.| ||    ..             . . .|.|.. .. .. .. .              . ..  |..|.  |.     . .  .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

CTK-------NSYYIVMEFYP
  .       .. .|.||. .
FKEGHNHKNDDELWICMEYMD
Kinase 90210.m00287.AA CMGC 936-1021 16 5e-06 14.79 In-house 1-142 (513) Show / Hide 
Range on Protein: 936-1021
Range on HMM: 1-142/513
Sequence Identity: 16% (23 aa)

YANGKHIASGAFGVVMKA----------------PGKDKPVAVKILQKSLNEFENPH--------LFEVYSEVSILDTCK---------------GDRR-
| . | | .|..||| |.                   .. ||.|.. .   . |            .  . |..||   .                ..  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VTQLVDFGCTKN-----------------SYYIVMEFYPFTLK
. .| |.  .||                 . |.|.|. . .|.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLY
Kinase 90210.m00287.AA ULK 1132-1147 62 1.7e-05 15.22 In-house 237-252 (329) Show / Hide 
Range on Protein: 1132-1147
Range on HMM: 237-252/329
Sequence Identity: 62% (10 aa)

SDIWSIGCLFFELLTG
.||||.||.|.|.|.|
CDIWSLGCIFYEMLYG
Kinase 90210.m00287.AA ULK 1132-1147 62 2e-05 15.27 In-house 233-248 (324) Show / Hide 
Range on Protein: 1132-1147
Range on HMM: 233-248/324
Sequence Identity: 62% (10 aa)

SDIWSIGCLFFELLTG
.||||.||.|.|.|.|
CDIWSLGCIFYEMLYG
Kinase 90210.m00287.AA GSK 936-953 50 0.000167 9.02 In-house 1-18 (328) Show / Hide 
Range on Protein: 936-953
Range on HMM: 1-18/328
Sequence Identity: 50% (9 aa)

YANGKHIASGAFGVVMKA
| . | |..|.|||| .|
YEEMKVIGHGSFGVVYQA
Kinase 90210.m00287.AA AGC 1059-1079 50 0.013545 0.93 In-house 179-200 (395) Show / Hide 
Range on Protein: 1059-1079
Range on HMM: 179-200/395
Sequence Identity: 50% (11 aa)

D-IKCDNVMLDFDGMPALADFG
| .| .|..|| ||   |.|||
DYLKPENILLDEDGHIKLTDFG