Gene 96726.m00087 (T.vaginalis)

96726.m00087

Species: T.vaginalis
Alias: TvagK0257, 96726.m00087
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
96726.m00087.AA Protein None 313 None Fasta, JSON
96726.m00087.kin_dom Protein Kinase Domain None 242 None Fasta, JSON

Protein domain

Protein domains of 96726.m00087.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 96726.m00087.AA S_TKc 16-260 28 4.6e-66 226.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 16-260
Range on HMM: 1-231/231
Sequence Identity: 28% (75 aa)

YEFLEEIGTGSFGKVCLIYSYQYKQKFALKIIPIKVFDENEIKSLASIDCPFITRLYQYMIMKDVVYLVMEFVPN---SLHKMLQEKGA------IEESK
||.|..|| |.||||.. .    ....|.|||.     ..||. | . ..|.| .|| ..   | .|.|||....   .|.......|       . |  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

CISIARQLLTGIKTCHEHNISHGDIKLSNVLVDVYGRPKLCDFGMASVSETKRFFNFQFRGSFPYVSPEILLKRPYDPLKADICAFGVLLYIMLTAKCPW
. ....|.. ... ||.|.| | |.| .|.|.|   . |.||||.| .          | |.  |..||.|   .|.. |.|. ..|..||.||. . |.
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPF

SGKDANTLTSNIFAGNVNIDLITNPDLANVIKMCLSIDPKKRPTADELTN-------MYIF
.  . ...  .|            |.. . |. ||  ||.||||| |. .       .  |
P--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 96726.m00087.AA Pkinase 16-259 26 7e-64 223.34 Pfam 1-293 (293) Show / Hide 
Range on Protein: 16-259
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

YEFLEEIGTGSFGKVCLIYSYQYKQKFALKIIPIKVFDE---------NEIKSLASIDCPFITRLYQYMIMKDVVYLVMEFVPN-----SLHKMLQ--EK
|.... || ||||.|.. .   . ...|.|||. .  ..         .||. ......|.| ||| ..  || .|.|||....     .|. ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GAI--EESKCISIARQLLTGIKTCHEHNISHGDIKLSNVLVDVYGRP----KLCDFGMASV--SETKRFFNFQFRGSFPYVSPEILLKRPYDPLKADICA
|..  .|  |.....|.| |.. ||...| | |.|..|.|.|  | .    |.|||| | .     .. ..  | |. .|..||......|.. |.|. .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MT-TFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGVLLYIMLTAKCPWSGK------DANTLTSNIFAGNVNIDLITN---------------------PDLANVIKMCLSIDPKKRPTADELTNM-YI
.|..||.||. . |..|.      | . .  .|  . .  |  .                      ...  .|| ||  ||||||||... .  ..
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 96726.m00087.AA CAMKL 16-254 26 1.9e-59 188.32 In-house 1-291 (297) Show / Hide 
Range on Protein: 16-254
Range on HMM: 1-291/297
Sequence Identity: 26% (78 aa)

YEFLEEIGTGSFGKVCLIYSYQY-KQKFALKIIP------IKVFDEN--------------EIKSLASID---CPFITRLYQYMIMKDV------VYLVM
|......|.|||||| |    .. ..| | |||       . . . |              ||. . ...    | | .||. .  ..       .||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFVPNS---LHKMLQEKGA----IEESKCISIARQLLTGIKTCHEHNISHGDIKLSNVLVDVYG--RPKLCDFGMASVSET-----KRFFNFQFRGSFPY
| ...    |. .....|     ..|. .  . ||.. ... ||.|.| | |||. |.|.|  |    |..|||..   .       ....  | || ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLK-TFCGSPPY

VSPEILLK--RPYDPLKADICAFGVLLYIMLTAKCPWSGK--------DANTLTSNIFAGNVNIDLITNP-DLANVIKMCLSIDPKKRPTADEL
 .|||...  .|||  |.|| . ||.|| |.. . |. .         .  .|   |  |  ...    . |. . |.  |  .|.||||....
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQI
Kinase 96726.m00087.AA CAMK 21-253 18 3.3e-58 185.83 In-house 1-418 (425) Show / Hide 
Range on Protein: 21-253
Range on HMM: 1-418/425
Sequence Identity: 18% (78 aa)

EIGTGSFGKVCLIYSYQYK------------QKFALKIIPIK-------------------------------VFD--ENEIKSLAS-------IDCPFI
..|.|||||| | .  . .            ||.| |||. |                                 .  ..||. . .       .| | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TRLYQYMIMKDV-------------------VYLVM---EFVPN-----SLHKMLQEK---------------GAIEESKCISIARQLLTGIKTCHEHNI
 .||...  ...                   .|.||   |....      |  ...|.               | ..|. .  . ||.. ... ||.|||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHGDIKLSNVLVDVY-----------------GRPKLCDFGMASVSETKRF-----------------------FNFQFRGSFPYVS-PEILLK------
 | |.|. |.|.|                   .  |..|||.| . . .                             | |. .|.. ||.|..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------RPYDPLKADICAFGVLLYIMLTAKCPWSGK-------------DANTLTSNIFAGNVN-IDLITNP-----------------------DLAN
       .||.. |.|. . ||.|||||. . |. |.             . . |  .| .|. . ..    |                       .  .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

VIKMCLSIDPKKRPTADE
 |. .|  ||.||.|...
LIRKMLQVDPEKRMTIEQ
Kinase 96726.m00087.AA MARK 16-254 31 3.7e-56 182.14 In-house 1-256 (262) Show / Hide 
Range on Protein: 16-254
Range on HMM: 1-256/262
Sequence Identity: 31% (82 aa)

YEFLEEIGTGSFGKVCLIYSYQYKQKFALKIIP-IKVFD-------ENEIKSLASIDCPFITRLYQYMI--MKDV-VYLVMEFVPN-SLHKMLQEK--GA
|..| .||.||..|| |  .  ...|.|.||..  | .|       . ||. . ..| | |..|....    .   .||.|| ... .|.  ....  | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IEESKCISIARQLLTGIKTCHEHNISHGDIKLSNVLVDVYG--RPKLCDFGMASVSETKRFFNFQFRGSFPYVSPEILLKRPYDPLKADICAFGVLLYIM
..|. .  | ||.. ... ||..|| | |||. |.|.|  |    |..|||..   .. .  |  | |. || .|||.||.|||  |.|| . ||.||.|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLN-TFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LTAKCPWSGKD--ANTLTSNIFAGNVNIDLITNPDLANVIKMCLSIDPKKRPTADEL
.. . |. |..   ..|  .| .|.  |     ... | |.  | ..|..|||..|.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEI
Kinase 96726.m00087.AA Ciliate-E2-Unclassified 16-260 21 7.1e-50 171.19 In-house 1-352 (352) Show / Hide 
Range on Protein: 16-260
Range on HMM: 1-352/352
Sequence Identity: 21% (75 aa)

YEFLEEIGTGSFGKVCLIYSYQYKQKFALKIIP-IKVFD----------------ENEIK-------------SLASIDCPFITRLYQYMIMKDVVYLVM
|.... ||.|.||||.. .  . ||..|.|..  |....                .|..|             .| ....||| ... .   |. .|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFVPNSLHKMLQEK------------------GAIEESKCI-----SIARQLLTGIKTCHEHN-ISHGDIKLSNVLVDVYG---RPKLCDFGMASVSET-
|....  ..   .|                    ..| ...      ...|.| |.. .|. | | | |||..|.|.|  |   ..|..||| .. ... 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---KRFF------------NFQFRGSFPYV----SPEILLKRPYDP---LKADICAFGVLLYIMLTAKCPWSGKDANT----------------LTSNIF
   . ..              .| |.  |     .||.| .  ||     |.|| ..||.|| ||. ..| .... .                 | .||.
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

AGNVNIDL--------ITNPDLANVIK----MCLSIDPKKRPTADELTNMYIF
..|....         . .|  .. |.     .|  .|.||.|.... |  .|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 96726.m00087.AA Ciliate-E2 16-260 18 5e-49 166.44 In-house 1-365 (365) Show / Hide 
Range on Protein: 16-260
Range on HMM: 1-365/365
Sequence Identity: 18% (71 aa)

YEFLEEIGTGSFGKVCLIYSYQYKQ------------------KFALKIIPIKVFDENEIKSLAS-----------------------IDCPFITRLYQY
|.|.. ||.|.||.|..   .. ..                  |.. ||. .|.. .|.|... .                       ...|.| ..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

MI--MKDVVYLVMEFVPN-SLHKMLQEK-----------GAIEESKCISIARQLLT---------------GIKTCHEHN-ISHGDIKLSNVLVDVYGRP
 .   .. .|||||..   .| . ....           . . | ... | .|.|                ... .|. | | | |||..|.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGMAS-----------VSETKRFFNFQ---------------------FRGSFPYVSPEILLKRPYDP--------LKADICAFGVLLYIMLTAKC
|..|||..             .. | . . .                     . |. .|..|||| . .||          |.|| ..||.||.||. | 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWSGKDANTLTSNIFAGNVNID------------------LITNPDLANVIKM----CLSIDPKKRPT-ADELTNMYIF
|.          .|  ......                  .   ..  . ||     .|  ||.||.| .... |  .|
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 96726.m00087.AA AGC 16-260 20 4.8e-46 115.89 In-house 1-395 (395) Show / Hide 
Range on Protein: 16-260
Range on HMM: 1-395/395
Sequence Identity: 20% (82 aa)

YEFLEEIGTGSFGKVCLIYSY------QYKQKFALKIIPIKV---------FDEN--E------------IKSLASID----------CPFITR-LYQYM
.|||  ||.||||||.|          . .. .|.|..  |.          . .  |             . |. ..          .|||.. |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

IMKDV--VYLVMEFVP----------N-SLHKMLQ---EKGAIEESKCISIARQ-------LLTGIKTCHE-HNISHGD-IKLSNVLVDVYGRPKLCDFG
  ||   .|.|||..|             |. .||    .|  .|. .  .| .       .. ..   |. ..| | | .|. |.| |  |  ||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

MASVSET--------------------------------------------------KRFFNFQFRG--SFPYVSPEILLKRPYDPLKADICA--FGVLL
.. .  .                                                  ||. .  | |  .  |..||||    |..  .|. .  .|.|.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

YIMLTAKCPWSGK----------DANTLTSNIFAG----NVNIDLITN------------PDLANVIKMCLSIDPKKRPT----------ADELTNMYIF
| ||| . | .|.          . . .  .|  |    | .. .  .            |.. . ||..|  ||.||..          |.|. |   |
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 96726.m00087.AA ULK 16-260 23 1.5e-42 146.33 In-house 1-329 (329) Show / Hide 
Range on Protein: 16-260
Range on HMM: 1-329/329
Sequence Identity: 23% (76 aa)

YEFLEEIGTGSFGKVCLIYSYQYK----QKFALKIIP----IKVFDE-----------NEIKSLASID--------CPFITRLYQYMIMKDV--VYLVME
|.  ...| ||||||.  .  . |    .|.| |.|.    ..  .|           |||| .  ..        .| | .|| .   ..   .|..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FVPN-SLHKMLQEKGA----------IEESKCISIARQLLTGIKTCHEHNISHGDIKLSNVLVDVY------------GRPKLCDFGMASVSETK---RF
. .   | . .....           ..|...|.. .|.| | |  |.||| | |||..|.|..              |. |..||| | . .      .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

FNFQFR------GSFPYVSPEILL----KRPYDPLKADICAFGVLLYIMLTAKCPWSGKDANTLT-----SNIFAG--------NVNIDLI-------TN
 .  .       |.  | .|.||     . ||.  |.||  .|...| ||. |.|...  .|..      ..|  .        . ...           
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PDLANVIKMCLSIDPKKRPTADELTNMYIF
|.. . |. .| .|.|.| . .|| |. .|
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 96726.m00087.AA ULK 16-260 22 1.9e-42 147.32 In-house 1-324 (324) Show / Hide 
Range on Protein: 16-260
Range on HMM: 1-324/324
Sequence Identity: 22% (72 aa)

YEFLEEIGTGSFG-KVCLIYSYQY---KQKFALKIIPIKVFDE---------------NEIKSLASID---CPF--ITRLYQYMIMKDV--VYLVMEFVP
|.  ...| |||| ||.  .  .    .|..| |.|..| . .               |||. .  ..   .|.  | .|| .   ..   .|..||. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

N-SLHKMLQEKGA---------IEESKCISIARQLLTGIKTCHEHNISHGDIKLSNVLVDVY------------GRPKLCDFGMASVSE---TKRFFNFQ
   | . .....          ..|...|.. .|.. | |  |.||| | |||..| |.               |. |..||| | . .      . . .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FR------GSFPYVSPEILL----KRPYDPLKADICAFGVLLYIMLTAKCPWSGKDANTLT----SN----------IFAGNVNIDL-----ITNPDLAN
.       |.  | .|.||     . ||.  |.||  .|...| ||. |.|...  .|..     .           |   ......     .  |.. .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VIKMCLSIDPKKRPTADELTNMYIF
 |. .| .|.|.| . .|. |. .|
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 96726.m00087.AA STE 16-259 20 4.8e-37 128.36 In-house 1-359 (359) Show / Hide 
Range on Protein: 16-259
Range on HMM: 1-359/359
Sequence Identity: 20% (75 aa)

YEFLEEIGTGSFGKVCLIYSY------QYKQK---------FALKIIPIKVFD----------------------ENEIKSLASID--CPFITRLYQYMI
.|..|.|| |.||.|.. .        . ...         .| |.....  .                      ..||| .   .  .|.| . | . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

MK-------DVVYLVMEFVP-NSLHKMLQEK--------------GAIEESKCISIARQLLTG-IKTCHEHNISHGDIKLSNVLVDVYGRPKLCDFGMAS
 .       | ....||...  || .....|              . ..||  . |.||.| |  .  |.|.| | ||| .|.|.      |||||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-VSE---------------TKRFFNFQFRGSFPYVSPEILLK------RPYDPLKADICAFGVLLYIMLTAKCPWSG-KDANTLTSNIFAG---------
 ...               |    .  | |.  . .||....       .||  |.||  .| ..  |.| | ||.  ..   .   .| .         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----NVNIDLITN---------------------PDLANVIKMCLSIDPKKRPTADELTN---MYI
    .    | ..                     |.. . |. || .||.|||||..| .     |
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 96726.m00087.AA CMGC 16-152 17 2e-34 109.87 In-house 1-251 (513) Show / Hide 
Range on Protein: 16-152
Range on HMM: 1-251/513
Sequence Identity: 17% (44 aa)

YEFLEEIGTGSFGKVCLIYS--------------YQYKQKFALKIIP-IKVFDE----------------NEIKSLASI-----------------DCPF
|| .. || |..|.|.  .                ..... |.|.|   . ..|                 ||| |  .                 . . 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ITRLYQYMIMKD-----------------VVYLVMEFVPNSLHKMLQEKG---------AIEESK------------CISIA------RQLLTGIK--TC
| .|| .   |.                  .|||.|.....|.......            .| .            . ..       .|.|.|.|   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HEHN--ISHGDIKLSNVLVDVYGRP--------------------KLCDFGMA
| |.  | | |.| .|.|..  ..                     |.||||.|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase 96726.m00087.AA TyrKc 16-258 19 5e-13 -12.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 16-258
Range on HMM: 1-280/280
Sequence Identity: 19% (55 aa)

YEFLEEIGTGSFGKVCL-IYSYQYKQKFALKIIP---IKVFDENEIKSLASI--DCPFITRLYQYMIMK-------DVVYLVMEFVPN-SLHKMLQEKGA
 ......| | ||.|.. ...    .. | | .    .. |  .|.. . ..  . | | ||| . . .       . ...|||..|. .|.. |.... 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDF-MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-IEESKCISIARQLLTGIKTCHEHNISHGDIKLSNVLVDVYGRPKLCDFGMASVSETK-------RFFNFQF--RGS--FPY--VSPEILLKRPYDPLKA
 .  .. .|.. |   |    |..|. | |.   |.||.  .. | .|||..   . .            .    |   .|.   .|| . .. . . | 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KS

DICAFGVLLY-IMLTAKCPWSG-----KDANTLTSNIFAGNVNIDLIT---------NPDLANVIKMCLSIDPKKRPTADELTNMY
|. .|||... |.   . |..|     ...  .  .. .|.                 ... ...|.|   ||..|||  |.    
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 96726.m00087.AA CMGC 226-260 28 0.000151 9.84 In-house 479-513 (513) Show / Hide 
Range on Protein: 226-260
Range on HMM: 479-513/513
Sequence Identity: 28% (10 aa)

DLITNPDLANVIKMCLSIDPKKRPTADELTNMYIF
..  .|.. . .| .| .||.||.||..  ..  |
RKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 96726.m00087.AA Pkinase_Tyr 16-113 21 0.001343 12.81 Pfam 1-119 (270) Show / Hide 
Range on Protein: 16-113
Range on HMM: 1-119/270
Sequence Identity: 21% (26 aa)

YEFLEEIGTGSFGKVCLIYSY----QYKQKFALKIIPIKVFDEN--------EIKSLASI-DCPFITRLYQYMI-MKDV--VYLVMEFVPN-SLHKMLQE
 .|....| |.||.|.. . .    . |.. | |... .  .|.        |.| . .. ..| | |||   .  ..   .|.|||..|. .|.. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----KGAIEESKCISIARQ
    |...  .  .....|
HREDKQPLTMKDLLQMCWQ
Kinase 96726.m00087.AA Pkinase_Tyr 231-258 28 0.319946 4.76 Pfam 243-270 (270) Show / Hide 
Range on Protein: 231-258
Range on HMM: 243-270/270
Sequence Identity: 28% (8 aa)

PDLANVIKMCLSIDPKKRPTADELTNMY
... ...|.|   ||..|||  |. .. 
DEIYDLMKQCWHYDPEDRPTFSEIHEQL