Gene 94734.m00211 (T.vaginalis)

94734.m00211

Species: T.vaginalis
Alias: 94734.m00211, TvagK0248
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94734.m00211.AA Protein None 313 None Fasta, JSON
94734.m00211.kin_dom Protein Kinase Domain None 241 None Fasta, JSON

Protein domain

Protein domains of 94734.m00211.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 94734.m00211.AA S_TKc 19-260 25 2.8e-57 197.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-260
Range on HMM: 1-231/231
Sequence Identity: 25% (67 aa)

YKALDFIGEGAYGKCLRVYSLKYYQTFVCKVISQVRSFNNEINSLASMSHPNIIKLYDHFTEYNKCFLILEDCEN--GDIINYLRNNN-------VSNQE
|. |. ||.||.||. ...  |  . . .|.|.  ... .||. | .  ||||.||||.| . .. ....| |..  ||   |.....        .  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LIRICYEIINVIEYIHSQGLCHLDIKPSNIIVDKNGRVKLADFGFSQSFDNLCNCDRIGTRLYRAPEVFEDKPFDPFKADIWSMGITLYYIVFGTFPFHD
  ...|.|.. .||.||.| .| |.||.|| .|.  ..|..|||..  .        .||. |.||||.   .....|.|.|| |..||  . |  ||..
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFPQ

YKEWINRLTLGVSSLRIPKFICDELNTVLEMSINVRPFMRKPMTEIKD--------VFS
... ....              .|.   ..   .. |  |    |.           . 
MQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 94734.m00211.AA Pkinase 19-209 29 7.3e-57 200.03 Pfam 1-214 (293) Show / Hide 
Range on Protein: 19-209
Range on HMM: 1-214/293
Sequence Identity: 29% (63 aa)

YKALDFIGEGAYGKCLRVYSLKYYQTFVCKVISQVRSFN---------NEINSLASMSHPNIIKLYDHFTEYNKCFLILEDCENG----DIINYLR---N
|. .  ||.|..|.. . .  .. .....|.|. ..            .||  .....||||..||| |.. ... ...| ||.|    |   |..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NNV--SNQELIRICYEIINVIEYIHSQGLCHLDIKPSNIIVDKNGRV----KLADFGFSQ---SFDNLCNCDRIGTRLYRAPEVFEDKPFDPFKADIWSM
...  | .|.....|.|.  .||.||.| .| |.||.|| .|.|| .    |..|||..       |  . .. ||. |.||||  . . .. |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITLYYIVFGTFPFHD
|..||. ..| .|| .
GCILYEMLCGRPPFPG
Kinase 94734.m00211.AA CAMK 24-209 18 1.6e-52 167.16 In-house 1-336 (425) Show / Hide 
Range on Protein: 24-209
Range on HMM: 1-336/425
Sequence Identity: 18% (64 aa)

FIGEGAYGKCLRVYSLKY------------YQTFVCKVIS---------------------------------QVRSFNNEINSLAS-------MSHPNI
 .|.|..||  ...  .              | . .|.|.                                   ... .||. . .       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYDHFT------------EYNK--------CFLIL---EDCENG----DIINYLRNN----------------NVSNQELIRICYEIINVIEYIHSQG
||||...               .|        .....   | |..|    |. .|.. .                 .. .|  |.   |.  ..|.||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

LCHLDIKPSNIIVDKN-----------------GRVKLADFGFSQSFDNLCNC-------------------------DRIGTRLYRA-PEVFED-----
 .|.|.|| || .|.|                 . .|..||||.. ||   |.                         .. ||  | | |||..      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KPFDPFKADIWSMGITLYYIVFGTFPFHD
        || ...|.|.||.|. ||  . |..|| .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYG
Kinase 94734.m00211.AA Ciliate-E2-Unclassified 19-212 23 2.8e-52 179.65 In-house 1-275 (352) Show / Hide 
Range on Protein: 19-212
Range on HMM: 1-275/352
Sequence Identity: 23% (64 aa)

YKALDFIGEGAYGKCLRVYSLKYYQTFVCKVISQVRSFN-----------------NEIN-------------SLASMSHPNIIKLYDHFTEYNKCFLIL
|| .  ||.|..||  ...  | .| .. | ........                 |...             .| .. ||.|.|....|. ........
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EDCENGDIINYLRN------------------NNVSNQELI-----RICYEIINVIEYIHSQG-LCHLDIKPSNIIVDKNG---RVKLADFGFSQSFDNL
| ||.|| ..|...                  . .. |. .     .....|.. .||.|...  .| ||||.||..|.||   ..|..|||.|   .. 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

-----------------CNCDRIGTRLYR----APEVFEDKPFDP---FKADIWSMGITLYYIVFGTFPFHDYKE
                   ....||  |     ||||.. .  |    .|.||||.|. ||...||..|| |...
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNC
Kinase 94734.m00211.AA CAMKL 19-216 26 8.9e-50 156.95 In-house 1-256 (297) Show / Hide 
Range on Protein: 19-216
Range on HMM: 1-256/297
Sequence Identity: 26% (69 aa)

YKALDFIGEGAYGKCLRVYSLKY-YQTFVCKVISQVRSFNN--------------------EINSLASMS---HPNIIKLYDHFTEYNK------CFLIL
|. .. .|.|..||       ..  .    |.|   .  |.                    ||. . ...   ||||||||....  ..      ..|..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EDCENGD--IINYLRNNN-----VSNQELIRICYEIINVIEYIHSQGLCHLDIKPSNIIVDKNG--RVKLADFGFSQSFD------NLCNCDRIGTRLYR
| |..|.    .|....       .  |  |.   |.  ..|.||.| .| |||| || .|.||   .|..|||||  ..      .     . |.  | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVFED--KPFDPFKADIWSMGITLYYIVFGTFPFHDYK-----------EWINR
|||.|..  ||.| .|.||||.|..|| .|.|..|| |             .|...
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIM
Kinase 94734.m00211.AA Ciliate-E2 19-215 22 1.7e-49 168.09 In-house 1-302 (365) Show / Hide 
Range on Protein: 19-215
Range on HMM: 1-302/365
Sequence Identity: 22% (70 aa)

YKALDFIGEGAYG-----KCLRV-----YSLKYYQT--------------FVCKVI--SQVRSFNNEINSL----------------ASMSHPNIIKLYD
|| .  ||.|..|     |  .|     . ... |               .  |..  .|......||. .                 ...||||||.|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

HFT--EYNKCFLILEDCENGDIINYLRNN------------NVSNQELIRICYEIIN---------------VIEYIHSQG-LCHLDIKPSNIIVDKNGR
.|     |...|..| |. ||   |..||            . . .| ..| ..|..                .||.||..  .| ||||.||..     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKLADFGFSQSFD------------NLCNCDR----------------------IGTRLYRAPEVFEDKPFDP--------FKADIWSMGITLYYIVFGT
.|..|||.|. .|            ...   .                      .||  | |||... |. |         .|.||||.|..||. .|| 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

FPFHDYKEWIN
.||  ... ..
PPF--QQQIKQ
Kinase 94734.m00211.AA ULK 19-216 27 8.5e-46 157.86 In-house 1-269 (329) Show / Hide 
Range on Protein: 19-216
Range on HMM: 1-269/329
Sequence Identity: 27% (74 aa)

YKALDFIGEGAYGKCLRVYSLKY----YQTFVCKVIS-----QVR----------SFNNEINSLASMS--------HPNIIKLYDHFTEY--NKCFLILE
|   . .|.|..||  . .  |      . ..||.|.     |            ...|||  .  .         ||||.|||| | .   | ...|.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

DCENGDIINYLRNN-----------NVSNQELIRICYEIINVIEYIHSQGLCHLDIKPSNIIVDKN------------GRVKLADFGFSQSFD-N-----
 |. ||  .|. .|           . | || | ... |.|   ..|...  | ||||.|| ....            |..|.|||||....| .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-LCNCD---RI-GTRLYRAPEVFE----DKPFDPFKADIWSMGITLYYIVFGTFP----FHDYKEWINR
 .. |    |. || || ||....     ||.. .|.||||.|. .|....|  |    | |....|..
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQ
Kinase 94734.m00211.AA ULK 19-207 28 1.9e-44 153.98 In-house 1-252 (324) Show / Hide 
Range on Protein: 19-207
Range on HMM: 1-252/324
Sequence Identity: 28% (71 aa)

YKALDFIGEGAYG-KCLRVYSLKY---YQTFVCKVIS--------QVR-------SFNNEINSLASMS---HPN--IIKLYDHFTEY--NKCFLILEDCE
|   . .|.|..| |  . .  |     | . ||.|.        . .       ...|||. .  .    |||  |.|||| | .   | ...|.| |.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDIINYLRNN----------NVSNQELIRICYEIINVIEYIHSQGLCHLDIKPSNIIVDKN------------GRVKLADFGFSQSFDN--LCNCDRI-
 ||  .|. .|          . | || | ... |.|   ..|...  | ||||.|| . ..            |..|.|||||....||  .  ...  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTRLYRAPEVFE----DKPFDPFKADIWSMGITLYYIVFGTFPF
        || || ||....     ||.. .|.||||.|. .|....|  ||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPF
Kinase 94734.m00211.AA MARK 19-212 33 3.9e-42 135.63 In-house 1-215 (262) Show / Hide 
Range on Protein: 19-212
Range on HMM: 1-215/262
Sequence Identity: 33% (73 aa)

YKALDFIGEGAYGKCLRVYSLKYYQTFVCKVIS-------QV-RSFNNEINSLASMSHPNIIKLYDHFT--EYNK-CFLILEDCENGDIINYLRNN---N
|| |  ||.|.|.|   . .... . .  |..        |  ...  ||. . ...|||||||.. .   . ..  .||.| ...|.  .|...     
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

VSNQELIRICYEIINVIEYIHSQGLCHLDIKPSNIIVDKNG--RVKLADFGFSQSFDNLCNCDRI-GTRLYRAPEVFEDKPFDPFKADIWSMGITLYYIV
 .  |  ||.  |.  ..| ||.. .| |||| || .|.||   .|..|||||  . . .  ..  ||  | |||.|. || | .|.||||.|. ||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

FGTFPFH--D--YKE
 |.|||   .  |||
CGYFPFDGDTQDYKE
Kinase 94734.m00211.AA CMGC 19-177 17 4.6e-37 118.69 In-house 1-296 (513) Show / Hide 
Range on Protein: 19-177
Range on HMM: 1-296/513
Sequence Identity: 17% (52 aa)

YKALDFIGEGAYGKCLRVYS--------------LKYYQTFVCKVISQVRSFN-----------------NEINSLASMS-----------------HPN
|. .. ||||.||.  . .                .. .    | |...  .                   ||  |  ..                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIKLYDHFTEYN-----------------KCFLILEDCENGDIINYLRNNN-----------------------------VSNQELIRICYEIINVIE--
|.||||.|.  |                 . .|. | ... |  .|..||.                              ..     ..| |.. ..  
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

YIHSQG--LCHLDIKPSNIIVDKN--------------------GRVKLADFGFSQSFDNL-----------------------CNCDRIGTRLYRAPEV
|.||..   .| |.||.|| ...|                    ||.|..|||.. ....                         . ... || |||||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI
Kinase 94734.m00211.AA STE 19-211 20 4.4e-36 124.95 In-house 1-272 (359) Show / Hide 
Range on Protein: 19-211
Range on HMM: 1-272/359
Sequence Identity: 20% (56 aa)

YKALDFIGEGAYGKCLRVYSLK---YY------------QTFVCKVIS----------------------QVRSFNNEINSLASMS--HPNIIKLYDHFT
.. ...||.||.|.  . .  |   ..            . .  |...                      .. .. .||. .  ..  ||||.| |... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EY-------NKCFLILEDCENGDIINYLRNNNVS---------------NQELIRICYEIINV-IEYIHSQGLCHLDIKPSNIIVDKNGRVKLADFGFSQ
         .......| ...| .   ....                   .....||..|.    .|.||..  | ||||.|| .     |||.|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SFDN-----------------LCNC-DRIGTRLYRAPEVFE------DKPFDPFKADIWSMGITLYYIVFGTFPFHDYK
....                   ..   .||  . |||| .      ||. | .|.|||| |.|.   . |  |.||..
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMH
Kinase 94734.m00211.AA TKL 25-212 16 1.4e-33 117.92 In-house 1-294 (364) Show / Hide 
Range on Protein: 25-212
Range on HMM: 1-294/364
Sequence Identity: 16% (50 aa)

IGEGAYGKCLRVYSLKYY--------QTFVCKVISQV--------------------------------RSFNNEINSLASMSHPNIIKLYDHFTEYNK-
||.|..|.  . .             .. . |....                                   ...||... . .||||....   .. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------CFLILEDCENGDIINYLRNNNVSNQELIRICYEIINVIEYIHSQG--------LCHLDIKPSNIIVDKNGR--------------VKL
            .... | |..|.  .||       . ..|....|   ..| ||..        . | |.|..|| ||.|..              .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADFGFSQSFDNLC---------------------NCDRIGTRLYRAPEVFEDKPFDP---------------FKADIWSMGITLYYIVFGTFPFHDYKE
.|||.|.....                       .. ..||  . ||||........                |.|..|.|| |. |. .  |..||..
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY
Kinase 94734.m00211.AA TyrKc 19-259 22 3.4e-12 -25.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-259
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

YKALDFIGEGAYGKCLRVYSLKYYQTFV----CKVISQVRSFNNEINSLASM--SHPNIIKLYDHFTEY-------NKCFLILEDCENGDIINYLRNNN-
 . .. .||||.|.   ||  ... . |    .|  . .. | .|.. . .   .||||..||   |.           ....| ...||  .|||..  
ITLGKKLGEGAFGE---VYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-VSNQELIRICYEIINVIEYIHSQGLCHLDIKPSNIIVDKNGRVKLADFGFSQSFDNL----CNCDRIGTR---LYR--------APEVFEDKPFDPFKA
 .....|. .|. | .  ||.||... | |.   |. |..|..|| .||| |   ..      . | . ..     .        |||.. .. |  .| 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS

DIWSMGITLYYIVFGTFPFHDYKE-----WINRLTLGV----SSLRIPKF--------ICDELNTVLEMSINVRPFMRKPMTEIKDVF
|.|| |.... |   |.    | .       |.  .        ...|.           ||. .. ..  .  | .|  ..||.. |
DVWSFGVCMWEIF--TYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 94734.m00211.AA Pkinase_Tyr 51-153 28 3e-07 25.19 Pfam 43-156 (270) Show / Hide 
Range on Protein: 51-153
Range on HMM: 43-156/270
Sequence Identity: 28% (32 aa)

SQ--VRSFNNEINSLASM-SHPNIIKLYDHFT-EYNK--CFLILEDCENGDIINYLRNN-----NVSNQELIRICYEIINVIEYIHSQGLCHLDIKPSNI
.|   ..| .|.. . .. .||||..||   | .      ....| ...||  .|||..     ... ..|. .|..| .  || .|... | |.   |.
EQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNC

IVDKNGRVKLADFG
 |..|. || .|||
LVTENNVVKICDFG