96281.m00300

Species: T.vaginalis
Alias: TvagK0612, 96281.m00300
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7

Sequence

Name Sequence Type Origin Length Description Download
96281.m00300.AA Protein None 300 None Fasta, JSON
96281.m00300.kin_dom Protein Kinase Domain None 279 None Fasta, JSON

Protein domain

Protein domains of 96281.m00300.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96281.m00300.AA CMGC 5-283 23 2.3e-98 323.89 In-house 1-513 (513) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-513/513
Sequence Identity: 23% (123 aa)

YLIGDKITEGTSPVIYKATDLRSN--------------EIVALKVSK---MDQ------EEDGVTISSMREITTLRNMS-----------------HPNI
| | .|| |||  | ||..| |.|              ||||.|  |   ..       |.||. |.. |||  |....                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

ITLREVITENE-----------------QLAVAFEYMAKNLRQFLEK--------RSRPLDPPL------------LQSYA------YQLLSGIN--YIH
..|..... ..                 .|   |||| ..| |....        | .||..               ...       ||.| |..  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SVG--YIHQQIEPSNILINAKGLL--------------------KIGGFGKARAYHHP------------------------MSRSVNTSQLLWYTAPEL
| .   ||  . |.||||| .. |                    ||. || ||.||..                        ..  | |   .|| |||.
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVT---RWYRAPEI

LVGT---------DYYGLGIDVWSAGCIIAEMARG--------QVLFPGDSN-----------IDMLARISNILGQPS---------------EEEWPE-
|.|          ..|. .||.||.|||.||| .|        . ||||.|.           ||.|..| ..|| |.               |||||. 
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNM

-------------------------------------FYRVINKMSLHLS-------------------EDFYS-------CFNNINPELVDLIKKLLTL
                                      .. ..  .|.                     |.| |       . ....|...||.||.|..
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

NPANRISANEALLHPYF
.|..||.| .|| ||||
DPDKRITAEQALQHPYF

Kinase 96281.m00300.AA CDK 5-283 35 1.1e-95 306.61 In-house 1-284 (284) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-284/284
Sequence Identity: 35% (113 aa)

YLIGDKITEGTSPVIYKATDLRSN-----EIVALKVSKMDQ-----EEDGVTISSMREITTLRNMSHPNIITLREVITEN-----------EQLAVAFEY
| . .|| |||  | ||| |....     .|||||  .|..     |..|. |.. |||..|... ||||..|..|.. .             |   |||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MAKNLRQFLEKRSRPLDPPLLQSYAYQLLSGINYIHSVGYIHQQIEPSNILINAKGL-----LKIGGFGKARAYH---------HPMSRSVNTSQLLWYT
|   | ....           ..| .|||.|..|.|| . .|  . |.||||| .|      |||. || |||..          ...  | |   ||| 
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVT---LWYR

APELLVGTDYYG--LGIDVWSAGCIIAEMAR---GQVLFPGDSNIDMLARISNILGQPSEEEWPEFYRVINKMSLHLSEDFYSCFNNINPELVDLIKKLL
||||| |.  |.   .||.||.|||.|||..   .. |||||| || | .|..|.| |.|. ||..    .                      ||. |.|
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------DLLNKML

TLNPANRISANEALLHPYF
...|..|||| .|| ||||
CYDPKKRISAEQALQHPYF

Kinase 96281.m00300.AA CDC2 5-283 38 3.3e-93 286.79 In-house 1-301 (301) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-301/301
Sequence Identity: 38% (115 aa)

YLIGDKITEGTSPVIYKATDLRSNEIVALKVSKMDQEEDG--VTISSMREITTLRNMS-HPNIITLREVITENEQLAVAFEYMAKNLRQFLE-KRS--RP
|    || |||  |.||. |...|.|||||  . .||..|  |  ...||| .| ..  ||||..|..|| .   |   |||.  .|..... . .   .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LDPPLLQSYAYQLLSGINYIHSVGYIHQQIEPSNILINAKGLLKIGGFGKARAYHHPMSRSV--NTSQLLWYTAPELLVGTDYYGLGIDVWSAGCIIAEM
..| |..||.||.|.|... |. . .|  . |.||||..|| .||. || |||   |.           ||| |||.| |  .| ...|.|| |||.|||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---ARGQVLFPGDSNIDMLARISNILGQPSEEEWPEFYRVI---NKMSLHLSEDFYSCFNN---------INPELVDLIKKLLTLNPANRISANEALLHP
   .    ||.||| || | .|  ||| |.|..||. .      |.       |. . . |         ..|| .||....| ..|..|||| ||| ||
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHP

YF
||
YF

Kinase 96281.m00300.AA CDK5 5-283 36 1.1e-84 267.45 In-house 1-287 (287) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-287/287
Sequence Identity: 36% (106 aa)

YLIGDKITEGTSPVIYKATDLRSNEIVALKVSKMDQEEDGVTISSMREITTLRNMSHPNIITLREVITENEQLAVAFEYMAKNLRQFLEKRSRPLDPPLL
|   .|| |||  ..||| .  . ||||||  ..|.|  ||  . .|||  |. . |.||. |  ||  .  |   ||.. . |. .....   .|... 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

QSYAYQLLSGINYIHSVGYIHQQIEPSNILINAKGLLKIGGFGKARAYHHPMSRSVNTSQLLWYTAPELLVGTDYYGLGIDVWSAGCIIAEMA-RGQVLF
.|. |||| |. . |.    |    | | ||| .| || . || |||.  |          ||| .|  | |   |   ||.||.|||.||||  |. ||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PGDSNIDMLARISNILGQPSEEEWPEF-----YR-VINKMSLHLSED-FYSCFNNINPELVDLIKKLLTLNPANRISANEALLHPYF
|| .  | | ||  |.| |.|..||       |.  ...   .  .  . .   . . .. || .|.| .||. ||||..|| ||||
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF

Kinase 96281.m00300.AA CDK7 5-283 34 3.4e-82 218.61 In-house 1-288 (288) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-288/288
Sequence Identity: 34% (101 aa)

YLIGDKITEGTSPVIYKATDLRSNEIVALKVSK----MDQEEDGVTISSMREITTLRNMSHPNIITLREVITENEQLAVAFEYMAKNLRQFLEKRSRPLD
| . ..| ||.  ..|||.|. ...||| |  |     .. .||.  . .|||  |. |.|.|.| |. ..     .   |..|   |    .  |  | 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

PPLLQSYAYQLLSGINYIHSVGYIHQQIEPSNILINAKGLLKIGGFGKARAYHHPMSRSVNTSQLL--WYTAPELLVGTDYYGLGIDVWSAGCIIAEMAR
|    .|. ..| |. | |     |  . | | |.|  | |||. || ||.|  |    . |.|    || ||||| |   || |.|.|| |||.||   
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSP--NRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELML

GQVLFPGDSNIDMLARISNILGQPSEEEWPEFYRVIN--KMSLHLS---EDFYSCFNNINPELVDLIKKLLTLNPANRISANEALLHPYF
    .|||| || | || ..|| |.|||||.     .  |.  .       .   |     .|.||.....|.|| .|... ..| .|||
RVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF

Kinase 96281.m00300.AA PITSLRE 5-283 35 1.3e-71 244.23 In-house 1-295 (295) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-295/295
Sequence Identity: 35% (105 aa)

YLIGDKITEGTSPVIYKATDLRSNEIVALKVSKMD--QEEDGVTISSMREIT-TLRNMSHPNIITLREVI--TENEQLAVAFEYMAKNLRQFLEKRS---
. . ..| |||  |.|.| | | .||||||  ||.  .| .|  | |.|||   |. . ||||....|..  .       ..||.   |.  .|. .   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

RPLDPPLLQSYAYQLLSGINYIHSVGYIHQQIEPSNILINAKGLLKIGGFGKARAYHHP---MSRSVNTSQLLWYTAPELLVGTDYYGLGIDVWSAGCII
 |  |.   .   |||.|. . |.   .|     ||.|.. || |||. || || |  |    .  | |   ||| ||||| |.. |   .|.|| ||| 
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVT---LWYRAPELLLGCKKYSTPVDMWSVGCIF

AEMARGQVLFPGDSNIDMLARISNILGQPSEEEWPEFYRVINKMSLH-LSEDFYSCFNNINP--ELV-----DLIKKLLTLNPANRISANEALLHPYF
||.  ...||.|.| || . .| . .| |.|  || .    .   .  ...  |.  ... |  ...     ||  ..||.||.|||.| .|| ||.|
AEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF

Kinase 96281.m00300.AA Pkinase 5-283 30 1.4e-66 232.26 Pfam 1-293 (293) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-293/293
Sequence Identity: 30% (92 aa)

YLIGDKITEGTSPVIYKATDLRSNEIVALKVSKMDQEEDGVTISSMR--EITTLRNMSHPNIITLREVITENEQLAVAFEYMAK-----NLRQFLE-KRS
| || || .|.. . ||...  ...|||.|. | . |.... ..  |  ||  .....||||..|... ...  . . .||. .      |  ... .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RPL--DPPLLQSYAYQLLSGINYIHSVGYIHQQIEPSNILINAKGLL----KIGGFGKARAYHHPMSRSVNTSQL--LWYTAPELLVGTDYYGLGIDVWS
...  ..  ...|.||.|.|..|.|| | ||  . |.||||. .| .    ||. || |. .    . | .|.    .|| |||.. |  |||  .|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

AGCIIAEMARGQVLFPGD----SNIDMLARISNILGQPSEEEWPEFYR--VINKMSLHLSEDFYSCFNNINPELVDLIKKLLTLNPANRISANEALLHPY
.|||..||. |. .|||.    . .|....| .|.| | ...||. ..    .  .    ..  . | |...|. |.||..|...|. |..| ..| ||.
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F

Kinase 96281.m00300.AA S_TKc 5-283 28 2.6e-66 227.53 SMART 1-231 (231) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-231/231
Sequence Identity: 28% (84 aa)

YLIGDKITEGTSPVIYKATDLRSNEIVALKVSKMDQEEDGVTISSMREITTLRNMSHPNIITLREVITENEQLAVAFEYMAK---NLRQFLEKRSRP---
| |..|| .|.  . ||... ....|||.|. |         .. .|||  |..  ||||..| .|. . . | . .||.     .|.....|| |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDPPLLQSYAYQLLSGINYIHSVGYIHQQIEPSNILINAKGLLKIGGFGKARAYHHPMSRSVNTSQL--LWYTAPELLVGTDYYGL-GIDVWSAGCII
  ...   ..|.||......|.|| | ||  . |.|||..    .||. || || .         |..   .|| |||.|     ||   .|.|| |||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

AEMARGQVLFPGDSNIDMLARISNILGQPSEEEWPEFYRVINKMSLHLSEDFYSCFNNINPELVDLIKKLLTLNPANRISANEALL-------HPYF
.||. |. .||       .... ...|                                 ||. |.|.|.|. .|..|..| |||        ||.|
YEMLCGYPPFP------QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 96281.m00300.AA MAPK 5-283 32 1.5e-60 207.47 In-house 1-328 (328) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-328/328
Sequence Identity: 32% (107 aa)

YLIGDKITEGTSPVIYKATDLR------SNEIVALK-VSKMDQEEDGVTISSMREITTLRNM-SHPNIITLREVITEN-----------EQLAVAFEYMA
| |  .| .|   |  .|.| |      ....||.| .|.  | .        |||  || .  |.||| |....|             ... . .|.| 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK-RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELME

KNLRQFLEKRSRPLDPPLLQSYAYQLLSG--INYIHSVGYIHQQIEPSNILINAKGLLKIGGFGKAR----AYHHP-------------MSRSVNTSQLL
 .|.| .. .  ||.    |.  ||.| |  . |||| . ||  . |||||.|  ..|||. || ||     |||.             |.  | |    
TDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVAT---R

WYTAPELLVG--TDYYGLGIDVWSAGCIIAEMAR-GQVLFPGDSNIDMLARISNILGQPSEEEW-----P-EFYRVINKM---SLHLSEDFYSCFNN---
|| |||.. .  .. |  ..|.||.||| ||| . ...||||.. || . .| ..|| |||| .     . . . .|  .     .   .... | |   
WYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF

-INPELVDLIKKLLTLNPANRISANEALLHPYF
  ||. .||..|.|...|  ||.. ||| ||||
NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF

Kinase 96281.m00300.AA CDK10 9-283 34 3.3e-60 206.36 In-house 5-285 (285) Show / Hide
Range on Protein: 9-283
Range on HMM: 5-285/285
Sequence Identity: 34% (97 aa)

DKITEGTSPVIYKATDLRSNEIVALKVSKMDQEEDGVTISSMREITTLRNMSHPNIITLREVITEN--EQLAVAFEYMAKNLRQFLEKRSRPLDPPLLQS
 .. |||  ..|.| | ||.||||||  .||.| ||. ||..|||. | .. |.||. |.||.  .  . . .  .|  . |   |.  . |      . 
NRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQPFTETQVKC

YAYQLLSGINYIHSVGYIHQQIEPSNILINAKGLLKIGGFGKARAYHHPMSRSVNTSQLLWYTAPELLVGTDYYGLGIDVWSAGCIIAEMARGQVLFPGD
 . |.| |. |.|.   ||  .  ||.|.  || .|.  || ||.|  |.         ||| |||||.|.      ||.| .|||..|.  .. |.|| 
IMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKPLMPGN

SNIDMLARISNILGQPSEEEWPEFYRVINKMSLHLSEDFY----SCFNNINPELVDLIKKLLTLNPANRISANEALLHPYF
| |  .  | ..|| |||. || |  .       |..  |      |. .      |.. |.  ||  |  |.|.|   ||
SEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF

Kinase 96281.m00300.AA PFTAIRE 5-283 33 2.9e-58 199.88 In-house 1-287 (287) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-287/287
Sequence Identity: 33% (97 aa)

YLIGDKITEGTSPVIYKATDLRSNEIVALKVSKMDQEEDGVTISSMREITTLRNMSHPNIITLREVITENEQLAVAFEYMAKNLRQFLEKRSRPLDPPLL
|.  .|  ||.   .||.     . .||||. ...||| |.     ||   |.|. | ||..|  .|   | |   |||. . | |...|    ..|   
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQEE-GTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

QSYAYQLLSGINYIHSVGYIHQQIEPSNILINAKGLLKIGGFGKARAYHHPMSRSVNTSQLLWYTAPELLVGTDYYGLGIDVWSAGCIIAEMARGQVLFP
. . .||| |  |.|     |  . | | || ..| ||   || |||   |     .    |||  |  | |   |   .|.| .|||  ||  || .||
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP

GDSNI-DMLARISNILGQPSEEEW------PEFYRVINKMSLHLSEDFYSCFNNIN--PELVDLIKKLLTLNPANRISANEALLHPYF
| ..| | | .|  .|| | |. |      |... . ..  .. ..     .. |   |.  ||..|.| ..| .|.||.||. ||||
GMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF

Kinase 96281.m00300.AA RCK 167-283 34 5.6e-34 104.98 In-house 178-298 (298) Show / Hide
Range on Protein: 167-283
Range on HMM: 178-298/298
Sequence Identity: 34% (42 aa)

WYTAPELLVGTDYYGLGIDVWSAGCIIAEMARGQVLFPGDSNIDMLARISNILGQPSEEEWPEFYRVINKMSLHL----SEDFYSCFNNINPELVDLIKK
|| |||.|    ||   .|.|. |||..|    . |||| | || .  | ...| |. ..||..|.  ..| . .    .    . ..|.......|..|
WYRAPECLLRCTYYNSPMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEK

LLTLNPANRISANEALLHPYF
.|. .|  ||.|..|| ||||
MLQWDPQKRITAQQALQHPYF

Kinase 96281.m00300.AA RCK 5-150 33 9.3e-33 101.05 In-house 1-162 (298) Show / Hide
Range on Protein: 5-150
Range on HMM: 1-162/298
Sequence Identity: 33% (55 aa)

YLIGDKITEGTSPVIYKATDLRSNEIVALKVSKMDQE-EDGVTISSMREITTLRNMS-HPNIITLREVITENE--QLAVAFEYMAKNLRQFLEK---RSR
| | ... .||  .  || .....|||| |  || |. ..   . . |||. || .. ||||| |.||| .|.  ||.  |||| .|| |...    | .
YQIIKQLGDGTYGCVMKAQNKETGEIVAIK--KMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRK

PLDPPL--LQSYAYQLLSGINYIHSVGYIHQQIEPSNILINA---------KGLLKIGGFGKAR
.|  .   . .. ||.| |....|. |. |  . | ||...           ...||. || .|
YLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCR

Kinase 96281.m00300.AA TyrKc 5-283 23 3.6e-14 6.39 SMART 1-280 (280) Show / Hide
Range on Protein: 5-283
Range on HMM: 1-280/280
Sequence Identity: 23% (72 aa)

YLIGDKITEGTSPVIYKATDLRSNEIVALKVSKMDQEEDGVTISSMREITTLRNM--SHPNIITLREVITEN-------EQLAVAFEYMAK-NLRQFLEK
   |.|. ||   ..||.|     . || |. | |          |||.  ...   .||||. |  |.|.        |.| . .|||.. .|...| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RSRPLDPPLLQSYAYQLLSGINYIHSVGYIHQQIEPSNILINAKGLLKIGGFGKARAYHHP----MSRSVNTSQ---LLW------YTAPELLVGTDY-Y
. . | .. | |...|  .| .|.|| ..||  .   |.|.....  ||. || .|. ..      | .. ...             .||| .   .. .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKF

GLGIDVWSAGCIIAEMA-RGQVLFPG-----DSNIDMLARISNILGQPSEEE----WPEFYRVINKMSLHLSEDFYSCFNNINPELVDLIKKLLTLNPAN
    |||| |  . |.  .||   ||      ||....... .    |  ..                          |    .|. ...|.    .|..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------FVCCPDEMYQIMKQCWHEDPED

RISANEALLHPYF
| . .|   | .|
RPTFSEI--HECF

Kinase 96281.m00300.AA Pkinase_Tyr 50-125 30 5e-13 44.73 Pfam 51-134 (270) Show / Hide
Range on Protein: 50-125
Range on HMM: 51-134/270
Sequence Identity: 30% (26 aa)

MREITTLRNM-SHPNIITLREVIT-ENEQ--LAVAFEYMAK-NLRQFLEKR---SRPLDPPLLQSYAYQLLSGINYIHSVGYIH
|||. ..... .||||. |  |.| . |.  . . .|||.. .|. .| |.    .||... | ....|  .| .| .| ..||
MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH