83714.m00243

Species: T.vaginalis
Alias: TvagK0758, 83714.m00243
External Links:
Annotation:

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
83714.m00243.AA Protein None 346 None Fasta, JSON
83714.m00243.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of 83714.m00243.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83714.m00243.AA GSK 40-323 39 1.7e-128 394.76 In-house 1-328 (328) Show / Hide
Range on Protein: 40-323
Range on HMM: 1-328/328
Sequence Identity: 39% (130 aa)

YNPLNIIGKGAFGVVFCARAP-----TGDV----VAIKKVLIDPRYK-NRELDIISTI---KHHNCITLRDSFRIQGRKKGE--IFLN-IVMDYYPMTLY
|   . || |.||||..| .      |...    ||||||. |.||| ||||.|.  .   .| |...|. .|  .. || |   ..| .||.| |.|||
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

DFTLNYRNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKP--GDKSVSYIASRFYRAPELILDCQVYGPPI
..   |....  .||..|||..||.| ||.|||.  |.||||||||.||...|||||||||||||...|  . ...||| ||.|||||||..|. |.  |
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQI

DIWASGCVIAEAINSASPLFVSETSNGQINAIIKIFGQPNPEDFADYAHGNSVPTDVQQ--------ETTLEK-------------------VLPG-HTP
|.|  |||.|| .    |||  ..|. |.  |||..| |. |..      .| |   ..         . . |                   ..   ||.
DVWSCGCVMAEML-KGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSM--NPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTD

PD-LIDLLKKCFIYNPNERITAEQAMAHPCF
.. .|||..||..|.|..|... .|.||| |
MQDWIDLISKCLVYDPKKRLSPLEACAHPFF

Kinase 83714.m00243.AA CMGC 40-323 20 2.4e-103 340.55 In-house 1-513 (513) Show / Hide
Range on Protein: 40-323
Range on HMM: 1-513/513
Sequence Identity: 20% (105 aa)

YNPLNIIGKGAFGVVFCARA---------------PTGDVVAIKKVLIDPRYKN----------------RELDIISTIK----------------HHN-
|  .. ||.|..|||. .|                 |. .|||||.  .. |..                ||. |   ..                ||| 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

CITLRDSFRIQG-RKKGEI----------FLNIVMDYYPMTLYDFTLNYR------------------------NQRLYVPILYIKLFSYQLFAGLR--Y
...|.|.|.  . .....            |..|..| ...||..  |..                        ..  | .| .|. ..||.. ||   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LHKRR--IVHRDIKPQNLLVNQET-------------------GVLKICDFGSAKIIKPGDK----------------------SVSYIASRFYRAPELI
.|...  |.|||.||.|.|.|...                   |.|||||||.|... | ..                        .|...|.|||||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LDC---------QVYGPPIDIWASGCVIAEAINS-------ASPLFVSETS-----------NGQINAIIKIFGQPN---------------PEDFADYA
| .         . |..|||.|. ||..|| ..          |||  ...             |.. |.|..| |.               .|.. .. 
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

HGNSVPT----------------------------DVQQETTLEKVLPGHTP----------------------------------PDLIDLLKKCFIYN
     ..                              ..  ..... |.| .                                  |..||||||...|.
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PNERITAEQAMAHPCF
|..|||||||..|| |
PDKRITAEQALQHPYF

Kinase 83714.m00243.AA S_TKc 40-323 26 2.1e-79 270.99 SMART 1-231 (231) Show / Hide
Range on Protein: 40-323
Range on HMM: 1-231/231
Sequence Identity: 26% (80 aa)

YNPLNIIGKGAFGVVFCARAPT-GDVVAIKKVLIDPRYKNRELDIISTIKHHNCITLRDSFRIQGRKKGEIFLNIVMDYYPM---TLYDFTLNYRNQRLY
|  |..|||||||.|...|    | .||||..    .   ||..| .  .| | ..| |.|.         .| .||.| .    .|.|.  ... ..|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--VPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKPGDKSVSYIASRFYRAPELILDCQVYGP-PIDIWASGCVIAE
   |   .. . ||.. .| |.|...|.|||.||.|.|...   ..||||||.|...       ... ...|.|||..     ||. ..|.|. ||...|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

AINSASPLFVSETSNGQINAIIKIFGQPNPEDFADYAHGNSVPTDVQQETTLEKVLPGHTPPDLIDLLKKCFIYNPNERITAEQAMA-------HPCF
 .    |.|       |.....|. |                                  .|...|...||. ..|..|.|| .|..       || |
MLC-GYPPFP------QMQMMFKKIG----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 83714.m00243.AA CDK 40-323 28 3.8e-72 230.08 In-house 1-284 (284) Show / Hide
Range on Protein: 40-323
Range on HMM: 1-284/284
Sequence Identity: 28% (93 aa)

YNPLNIIGKGAFGVVFCARAPT-G-----DVVAIKKVLIDP--------RYKN---RELDIISTIKHHNCITLRDSFRIQ----GRKKG--EIFLNIVMD
|  |. || |..|||. ||    |     ..||.||. ..                ||  .   . |.| ..|.| .        . |.  |  | .|..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YYPMTLYDFTLNYRNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGV-----LKICDFGSAKIIK-------PGDKSVSYIASRF
| .. |. .               || . .||  || |.|...|.|||.||||.|.| ..|.     ||| ||| |..         |  .  . .  . 
YMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILIN-NNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLW

YRAPELILDCQVYG--PPIDIWASGCVIAEAIN--SASPLFVSETSNGQINAIIKIFGQPNPEDFADYAHGNSVPTDVQQETTLEKVLPGHTPPDLIDLL
|||||| | .. |.  .|||.|. ||..|| ..  .  |||  ..   |.  |..|.| |....  .  .                           |||
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------DLL

KKCFIYNPNERITAEQAMAHPCF
 |.. |.|. ||.||||. || |
NKMLCYDPKKRISAEQALQHPYF

Kinase 83714.m00243.AA Pkinase 40-323 27 5.3e-67 233.7 Pfam 1-293 (293) Show / Hide
Range on Protein: 40-323
Range on HMM: 1-293/293
Sequence Identity: 27% (85 aa)

YNPLNIIGKGAFGVVF-CARAPTGDVVAIKKVLIDPRYKNR--------ELDIISTIKHHNCITLRDSFRIQGRKKGEIFLNIVMDYYPMTLYDFTLNY-
|  . .||.|.||.|. | .  ||..||.|..  . . ..         |. |   ..| | ..|.|.|.     |..|   .||.| ...||     . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIY--MVMEYCEGGLY-VMDLFD

-----RNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVL----KICDFGSAKI--IKPGDKSVSYIASRFYRAPELILDCQVYG
     |. ..| .   .| . ||.. || |.|...|.|||.||.|.|.. ..|..    ||||||.||   . ..    ..  ...|.|||.|...| ||
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG

PPIDIWASGCVIAEAINSASPLFVSE-TSNGQINAIIKIFGQPNPEDFADYAHGNSVP----TDVQQETTLEKVLPGHTPPDLIDLLKKCFIYNPNERIT
|..|.|. ||...| ..   |.| .. .. . .. . .|.    |.   |.   .|..    .. . . . ....   ......|..|.|. ..|..|.|
PKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPT

AEQAMAHPCF
|||.. || |
AEQILQHPWF

Kinase 83714.m00243.AA RCK 111-323 34 1.6e-48 151.95 In-house 75-298 (298) Show / Hide
Range on Protein: 111-323
Range on HMM: 75-298/298
Sequence Identity: 34% (79 aa)

LNIVMDYYPMTLYDFTLNYRNQRLYVPILY--IKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQE--------TGVLKICDFGSAKIIKPGDKS--VS
| .|. |  | || .. ..   | |.|     ||   ||...|| ..||  . |||.|| |.... .        ....||.|||... |   .|     
LYFVFEYMDMNLYQMMKDFKERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIR--SKPPYTD

YIASRFYRAPELILDCQVYGPPIDIWASGCVIAEAINSASPLF--VSETSNGQINAIIKIFGQPNPEDFADYA-HGNSVPTDVQQ--ETTLEKVLPGHTP
|. .| |||||..| |. |  |.|||| ||...| . .  |||   ||    ||. |.|. | ||..|  |   . ...  . .|   . |....|   .
YVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYE-LYMLRPLFPGSSEID--QIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPN-CS

PDLIDLLKKCFIYNPNERITAEQAMAHPCF
.|.|.|..|.  ..|..||||.||  || |
QDCIELMEKMLQWDPQKRITAQQALQHPYF

Kinase 83714.m00243.AA MAPK 141-323 33 1.9e-45 155.01 In-house 117-328 (328) Show / Hide
Range on Protein: 141-323
Range on HMM: 117-328/328
Sequence Identity: 33% (72 aa)

IKLFSYQLFAG--LRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKPGDKSV---------------SYIASRFYRAPELILD--CQVYGPPI
|. | ||.  |  | |.|  ...|||.|| |.|||.. . ||||||| | .| | ..                  |.| |.|||||..|    . |   .
IQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNEN-CDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAV

DIWASGCVIAEAINSASPLFVSETSNGQINAIIKIFGQPNPEDFADYAH-----GNSVPT----DVQQETTLEKVLPG---HTPPDLIDLLKKCFIYNPN
|.|. ||  || ..   |||  . .  |.| |... | | .|.|  .        | .        ..  ..||..|.   .. |. ||||.|    .|.
DMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTP-SEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPD

ERITAEQAMAHPCF
.|||.|.|..|| |
KRITVEEALQHPYF

Kinase 83714.m00243.AA CDC2 40-257 30 3.1e-43 130.4 In-house 1-222 (301) Show / Hide
Range on Protein: 40-257
Range on HMM: 1-222/301
Sequence Identity: 30% (71 aa)

YNPLNIIGKGAFGVVFCAR-APTGDVVAIKKVLIDPRYKN--------RELDIISTIK-HHNCITLRDSFRIQGRKKGEIFLNIVMDYYPMTLYDFTLNY
|  .. ||.| .|||. ..   |...||.||. ..             ||. ..  .| | | ..|.| . .         | .| .|. | |  .. ..
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-------NKLYMVFEYLDMDLKKYMDMS

RNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIK-PGDKSV--SYIASRFYRAPELILDCQVYGPPIDIWAS
  .. ..|  ..| . ||.  |. ..| |||.|||.||||.|.. ..|..|| ||| |. .  | ..      .  . |||||. | |. |  |.|.|. 
IPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILID-KKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSI

GCVIAEA-IN-SASPLFVSETSNGQINAIIKIF
||..||  .. .  |||  .    .|  . |||
GCIFAEMFMDVTKKPLFHGDS---EIDQLFKIF

Kinase 83714.m00243.AA CAMK 45-229 16 2e-40 127.51 In-house 1-323 (425) Show / Hide
Range on Protein: 45-229
Range on HMM: 1-323/425
Sequence Identity: 16% (54 aa)

IIGKGAFGVVFCARAP-TG------------DVVAIKKVLID-----------------------------PRYKN---RELDIIST-------IKHHNC
..|.|.||.|. ..   |.              |||| .  .                             |. .    ||..| ..       ..| | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ITLRDSFR---------IQG-RKKG-----EIFLNIVM---DYYPMT-----LYDFTLNYRNQR-----------LYVPILYIKLFSYQLFAGLRYLHKR
| | . .          . .   .      . .. .||   .| .       |.|.    .. .            ...    . .  |.  ...|.|..
IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

RIVHRDIKPQNLLVNQET----------------GVLKICDFGSAKIIKP------------------------GDKSVSYIASRFYRA-PELILD----
 |||||.|| |.|...                  . .||.||| |....|                        |.|   .  .  | | ||...     
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------CQVYGPPIDIWASGCV
          . |||..|.|. |..
NMQNATDEEKPYYGPKCDMWSCGVI

Kinase 83714.m00243.AA ERK 141-323 36 4.3e-39 136.21 In-house 110-307 (307) Show / Hide
Range on Protein: 141-323
Range on HMM: 110-307/307
Sequence Identity: 36% (72 aa)

IKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKPGDKSV---------SYIASRFYRAPELILDCQVYGPPIDIWASGCVIA
.. | ||.  || |.|   ..|||.|| |.|||   ..||||||| | .. ..  .           |.|.| |||||..|  | |  ..|||. || .|
CQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSN-CDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFA

EAINSASPLFVSETSNGQINAIIKIFGQP-NPEDFADY------AHGNSVPTDVQQETTLEKVLPGHT-PPDLIDLLKKCFIYNPNERITAEQAMAHPCF
| ..   |||  . . .|||.|..| | |   ||. .           . |  |..   .|.. | .   |. ||||.|    .|..|||.|.. .|| |
EMLG-RKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEECLEHPYF





Kinase 83714.m00243.AA CDKL 146-232 46 2.8e-37 124.99 In-house 105-192 (286) Show / Hide
Range on Protein: 146-232
Range on HMM: 105-192/286
Sequence Identity: 46% (41 aa)

YQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIK-PGDKSVSYIASRFYRAPELILDCQVYGPPIDIWASGCVIAE
.|.  .. ..||  ..|||||| |.|..   |..|.|||| |.... ||.    | | | |||||| ..   ||.|.|||| |||.||
WQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAE

Kinase 83714.m00243.AA DYRK 40-263 32 3e-34 120.12 In-house 1-226 (320) Show / Hide
Range on Protein: 40-263
Range on HMM: 1-226/320
Sequence Identity: 32% (77 aa)

YNPLNIIGKGAFGVVF-CARAPTGDVVAIKKVLIDPRYKN---RELDIISTIKHH------NCITLRDSFRIQGRKKGEIFLNIVMDYYPMTLYDFTLNY
|  | .|||| || |. |    |.. |||| .   .|. .   .|. |.. .. .      .|. . |.|  ..      .| || . . | ||.|  |.
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRN------HLCIVFELLSMNLYEFLKNN

RNQRLYVPILYIKLFSYQLFAGLRYLHKR-RIVHRDIKPQNLLVNQ--ETGVLKICDFGSAKIIKPGDKSVSYIASRFYRAPELILDCQVYGPPIDIWAS
. | .  .. ... | .|.. .|..|||  .|.| |.|| | ...|      .|..||||.  ..   .  .|| |||||||| || |. |. .||.|  
HFQGF-FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQ--RIYTYIQSRFYRAPEVILGCP-YCYAIDMWSL

GCVIAEAINSASPLFVSETSNGQINAIIKIFGQPNPE
||..|| .    |||  |. . |.. |. ..| |...
GCILAE-LFTGWPLFPGENEYDQLACIMEVLGMPPKW

Kinase 83714.m00243.AA TyrKc 40-323 21 8.2e-13 -15.49 SMART 1-280 (280) Show / Hide
Range on Protein: 40-323
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

YNPLNIIGKGAFGVVFCARAPTGDVVAIKKVLIDPRYKN--RELDIISTI--KHHNCITLRDSFRIQGRKKGEIF-----LNIVMDYYPM-TLYDFTLNY
   . ..| ||||.|. ...     ||.|..  |   .   ||. | . .  .| | . |    . |||.    |     | ||| | |   | |.  ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN----FMYIEPLMIVMEYMPHGDLKDYLRKH

RNQRLYVPILYIKLFSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFGSAKIIKPG--------DKSVSY-IASR-----FYRAPELILDCQ
|..   ..      |..|  .| .|||.....|||.   | ||. .  . ||.||| .. |. .         ....    ..        ||| | .  
RPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

VYGPPIDIWASGCVIAEAINSASPLFVSE----TSNGQ-INAIIKIFGQPNPED----FADYAHGNSVPTDVQQETTLEKVLPGHTPPDLIDLLKKCFIY
.. .  |.|. | .. |      .    .     || . |. . . .  | |..                              . |... .. |.|  .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------F-VCCPDEMYQIMKQCWHE

NPNERITAEQAMAHPCF
.|..| | ..   | ||
DPEDRPTFSEI--HECF

Kinase 83714.m00243.AA CDKL 277-323 38 6.1e-12 37.11 In-house 240-286 (286) Show / Hide
Range on Protein: 277-323
Range on HMM: 240-286/286
Sequence Identity: 38% (18 aa)

DVQQETTLEKVLPGHTPPDLIDLLKKCFIYNPNERITAEQAMAHPCF
....  .||| .|.   . ..|..|||.  .| ||.|.||.| || |
EIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF

Kinase 83714.m00243.AA CAMK 294-323 33 2.9e-11 31.8 In-house 396-425 (425) Show / Hide
Range on Protein: 294-323
Range on HMM: 396-425/425
Sequence Identity: 33% (10 aa)

PDLIDLLKKCFIYNPNERITAEQAMAHPCF
.. .||..|.  ..|..|.|.||...|| .
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 83714.m00243.AA DYRK 278-323 28 9.1e-11 36.74 In-house 276-320 (320) Show / Hide
Range on Protein: 278-323
Range on HMM: 276-320/320
Sequence Identity: 28% (13 aa)

VQQETTLEKVLPGHTPPDLIDLLKKCFIYNPNERITAEQAMAHPCF
..  . .. ..      ...|..|||....|..|||..||. || |
PPGRRNWDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF

Kinase 83714.m00243.AA CDC2 280-323 32 4.7e-10 26.56 In-house 250-301 (301) Show / Hide
Range on Protein: 280-323
Range on HMM: 250-301/301
Sequence Identity: 32% (17 aa)

QETTLEKVLPG--------HTPPDLIDLLKKCFIYNPNERITAEQAMAHPCF
... |.|..|          ..|. ||||..  .|.|. ||.|..|..|| |
KPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF

Kinase 83714.m00243.AA MAPK 40-70 42 1.5e-08 25.43 In-house 1-38 (328) Show / Hide
Range on Protein: 40-70
Range on HMM: 1-38/328
Sequence Identity: 42% (16 aa)

YNPLNIIGKGAFGVVFCARAP-------TGDVVAIKKV
|..|  ||.||.|||. |.         .|. |||||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKI

Kinase 83714.m00243.AA ERK 40-70 43 4.1e-07 22.75 In-house 1-37 (307) Show / Hide
Range on Protein: 40-70
Range on HMM: 1-37/307
Sequence Identity: 43% (16 aa)

YNPLNIIGKGAFGVVFCAR-AP-----TGDVVAIKKV
|. .. ||.||.|||. |.  .     ||. |||||.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKI

Kinase 83714.m00243.AA RCK 40-69 41 5.5e-07 17.89 In-house 1-31 (298) Show / Hide
Range on Protein: 40-69
Range on HMM: 1-31/298
Sequence Identity: 41% (13 aa)

YNPLNIIGKGAFGVVFCARA-PTGDVVAIKK
|. .. .|.|..|.|. |..  ||..|||||
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKK

Kinase 83714.m00243.AA Pkinase_Tyr 144-185 40 3e-06 21.84 Pfam 116-156 (270) Show / Hide
Range on Protein: 144-185
Range on HMM: 116-156/270
Sequence Identity: 40% (17 aa)

FSYQLFAGLRYLHKRRIVHRDIKPQNLLVNQETGVLKICDFG
...|  .|. ||. ....|||.   | ||. .  | ||||||
MCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFG

Kinase 83714.m00243.AA CDKL 40-69 48 5.2e-05 13.07 In-house 1-31 (286) Show / Hide
Range on Protein: 40-69
Range on HMM: 1-31/286
Sequence Identity: 48% (15 aa)

YNPLNIIGKGAFGVVF-CARAPTGDVVAIKK
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YEKLGKVGEGSYGVVMKCRNKETGQIVAIKK

Kinase 83714.m00243.AA Pkinase_Tyr 40-91 23 0.015957 9.17 Pfam 1-65 (270) Show / Hide
Range on Protein: 40-91
Range on HMM: 1-65/270
Sequence Identity: 23% (15 aa)

YNPLNIIGKGAFGVVFCARAP-----TGDVVAIKKVLIDPRYKN-------RELDIISTI-KHHN
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ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPN