Gene 87414.m00318 (T.vaginalis)

87414.m00318

Species: T.vaginalis
Alias: TvagK0759, 87414.m00318
External Links:
Annotation:

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
87414.m00318.AA Protein None 355 None Fasta, JSON
87414.m00318.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of 87414.m00318.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87414.m00318.AA GSK 45-328 40 1e-132 407.91 In-house 1-328 (328) Show / Hide 
Range on Protein: 45-328
Range on HMM: 1-328/328
Sequence Identity: 40% (133 aa)

YRPIKVIGQGAFGIVYCARAV----DGSIV-----AIKKVLLDPRYK-NRELETMQEI---NNRYCIRLCSAFKTPGRKPKE--YYLN-LVMDYLPLSLH
|. .||||.|.|| ||.| .     . . .     |||||. |.||| ||||. |...   .   ..||  .| . . |. |   |.| |||.|.|  |.
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

QFNMNYRKERKYPPLLYVKLFAFQMFAGLNYIHSIGVTHRDLKPQNILCDMESGELKICDFGSAKQLVP--GEKSVSYIASRYYRAPELIFDCVYYTSAI
|.   |.| ..  |....||...||| ||.|.||.|. |||.||||||.| ..|.||||||||||||.|  .|...||| |||||||||||.| .||..|
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQI

DIWAGACVVAEMLMAGMPIFAGGSSLGQLHEIVKVLGPPTEDDMNSFQHGA-DIPLS-----SNPGIGLEN-------------------VLPR-HTPPD
|.|   ||.||||  | |.|.| ||. || ||.|.|| ||.... |.      .           .. .                     .. . ||...
DVWSCGCVMAEML-KGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTDMQ

-IMDLLKSIFIYNPSKRPTALECIKHPCF
 ..||......|.|.||...||...|| |
DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase 87414.m00318.AA CMGC 45-328 20 2.3e-101 333.93 In-house 1-513 (513) Show / Hide 
Range on Protein: 45-328
Range on HMM: 1-513/513
Sequence Identity: 20% (107 aa)

YRPIKVIGQGAFGIVYCARA---------------VDGSIVAIKKVLLDPRYKN----------------RELETMQEIN----------------NRY-
|  ||.||.|..|.|| .|                 .. ||||||. ... |..                ||.. ....|                ..  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

CIRLCSAFKTPGRKPKEY-----------YLNLVMDYLPLSLHQFNMNYRKE------------------------RKYPPLLYVKLFAFQMFAGLN--Y
...|   |.... ...||           .|.||..|.. .|.|.  |...                          || .. ... ...|.. ||.  |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

IHSIG--VTHRDLKPQNILCDME-------------------SGELKICDFGSAKQLVPG----------------------EKSVSYIASRYYRAPELI
.|| .  . ||||||.||| . .                   .|.|||||||.|... |                       .   .|...|.|||||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

FDC---------VYYTSAIDIWAGACVVAEMLMA-------GMPIFAGGSS-----------LGQLHEIVKVLGPP----------------TEDDMNSF
. .          .||..||.|. .|. |||..        | |.| | |.           . ||..|.||||.|                .|...|  
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

QHGADIP---------------------------LSSNPGIGLENVLPRHTP----------------------------------PDIMDLLKSIFIYN
.    ..                           .   |.. ..|. |.| .                                  |.  |||| ...|.
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PSKRPTALECIKHPCF
|.||.|| .. .|| |
PDKRITAEQALQHPYF
Kinase 87414.m00318.AA S_TKc 45-328 26 2.5e-76 260.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 45-328
Range on HMM: 1-231/231
Sequence Identity: 26% (80 aa)

YRPIKVIGQGAFGIVYCARAVD-GSIVAIKKVLLDPRYKNRELETMQEINNRYCIRLCSAFKTPGRKPKEYYLNLVMDYLPL---SLHQFNMNYRKERKY
|. ...||.|||| ||..| .. | |||||..    .   ||.. ... .  . ..|  .| .        .| .||.|..    .|...  ........
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--PPLLYVKLFAFQMFAGLNYIHSIGVTHRDLKPQNILCDMESGELKICDFGSAKQLVPGEKSVSYIASRYYRAPELIFDCVYYTS-AIDIWAGACVVAE
   |   .. .. |.. .|.|.|| |. ||||||.|||.|    ..||||||.|.||       ... ...|.|||..     |.  ..|.|.  |...|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MLMAGMPIFAGGSSLGQLHEIVKVLGPPTEDDMNSFQHGADIPLSSNPGIGLENVLPRHTPPDIMDLLKSIFIYNPSKRPTALECIK-------HPCF
||  | | |       |.... |..|                                  .|.  |... .. ..|.||||| |. .       || |
MLC-GYPPFP------QMQMMFKKIG----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87414.m00318.AA CDK 45-328 28 3.4e-68 217.21 In-house 1-284 (284) Show / Hide 
Range on Protein: 45-328
Range on HMM: 1-284/284
Sequence Identity: 28% (92 aa)

YRPIKVIGQGAFGIVYCARAVD-G-----SIVAIKKVLLDP--------RYKN---RELETMQEINNRYCIRLCSAFKTP-----GRKPK-EYYLNLVMD
|  .. ||.|..|.|| ||  . |      |||.||. ..                ||  ...|. . . ..|   . |      . | | |  | .|..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YLPLSLHQFNMNYRKERKYPPLLYVKLFAFQMFAGLNYIHSIGVTHRDLKPQNILCDMESGE-----LKICDFGSAKQLV-------PGEKSVSYIASRY
|..  | ..               .| . .|.  ||.|.|| .. ||||||||||  .. ||     ||| ||| |.          |  .  . .  . 
YMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILI-NNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLW

YRAPELIFDCVYYT--SAIDIWAGACVVAEMLM--AGMPIFAGGSSLGQLHEIVKVLGPPTEDDMNSFQHGADIPLSSNPGIGLENVLPRHTPPDIMDLL
|||||| . .  |.   .||.|.  |. |||..  .. |.| | | . ||. | ...| ||||.  .. .  |                        |||
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------DLL

KSIFIYNPSKRPTALECIKHPCF
 . . |.|.|| .| .. .|| |
NKMLCYDPKKRISAEQALQHPYF
Kinase 87414.m00318.AA Pkinase 45-328 26 4.2e-64 224.08 Pfam 1-293 (293) Show / Hide 
Range on Protein: 45-328
Range on HMM: 1-293/293
Sequence Identity: 26% (85 aa)

YRPIKVIGQGAFGIVYCARAVDGSI-VAIKKVLLDPRYKNR--------ELETMQEINNRYCIRLCSAFKTPGRKPKEYYLNLVMDYLPL-----SLH--
|. ...||.|.|| || .. .. .. ||.|.. .. . ..         |.. |...|  . .||  .| .      . .. .||.|..      .|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY

--QFNMNYRKERKYPPL----LYVKLFAFQMFAGLNYIHSIGVTHRDLKPQNILCDMESGEL----KICDFGSAKQ--LVPGEKSVSYIASRYYRAPELI
           ... ..      .| .. |.. ||.|.|| |. ||||||.|||.| . |..    ||||||.|||  . ...   ..  ...|.|||.|
IST--------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVI

FDCVYYTSAIDIWAGACVVAEMLMAGMPIFAGG----SSLGQLHEIVKVLGPPTEDD---------MNSFQHGADIPLSSNPGIGLENVLPRHTPPDIMD
 .. ||....|.|.  |...|||  | |.| |     . . |.. |....|||.. |          . |.|           . .. . .. ....  |
RGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------F-HWTF-HN-WSEECKD

LLKSIFIYNPSKRPTALECIKHPCF
..|... ..|.||||| .. .|| |
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87414.m00318.AA RCK 151-328 32 8.5e-50 156.02 In-house 112-298 (298) Show / Hide 
Range on Protein: 151-328
Range on HMM: 112-298/298
Sequence Identity: 32% (62 aa)

FQMFAGLNYIHSIGVTHRDLKPQNILCDME--------SGELKICDFGSAKQLVPGEKSVS----YIASRYYRAPELIFDCVYYTSAIDIWAGACVVAEM
.| ..||...|. |  |||||| ||.| ..        .. .||.|||...       |      |. .|.|||||..  | ||.| .||||  |. .| 
YQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREI----RSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYEL

LMAGMPIFAGGSSLGQLHEIVKVLGPPTEDDMNSFQ---HGADIPLSSNPGIGLENVLPRHTPPDIMDLLKSIFIYNPSKRPTALECIKHPCF
 |   | |.| | . |...|.||.| |. .| . ..   ..  . . . .|..|. ..|.  ..| ..|..    ..|.||.|| ....|| |
YML-RPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPN-CSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 87414.m00318.AA MAPK 146-328 34 3e-48 164.87 In-house 117-328 (328) Show / Hide 
Range on Protein: 146-328
Range on HMM: 117-328/328
Sequence Identity: 34% (73 aa)

VKLFAFQMFAG--LNYIHSIGVTHRDLKPQNILCDMESGELKICDFGSAKQLVPGEKSV---------------SYIASRYYRAPELIFD--CVYYTSAI
.. | .|.  |  | |||| .| |||||| |||.. | ..||||||| | .. | ..                  |.| |.|||||...      || |.
IQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVN-ENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAV

DIWAGACVVAEMLMAGMPIFAGGSSLGQLHEIVKVLGPPTEDDMNSFQ--HGADIPLSSN------PGIGLENVLPR---HTPPDIMDLLKSIFIYNPSK
|.|.  |  ||||  . |.| | ... |.  |..||| |.|....  .  . |   ..|.      |.. .|...|    .. |.  |||.     .|.|
DMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDK

RPTALECIKHPCF
| |. |.. || |
RITVEEALQHPYF
Kinase 87414.m00318.AA CDK-Unclassified 45-269 29 4.5e-47 152.81 In-house 1-262 (324) Show / Hide 
Range on Protein: 45-269
Range on HMM: 1-262/324
Sequence Identity: 29% (80 aa)

YRPIKVIGQGAFGIVYCARAVDGS-IVAIKKVLLDP-------------RYK---NRELETMQEINNRYCIRLCSAFKTPGRKPKE---YYLN------L
|| ....|.|.||.|. |.  . . .|||||. .               . |   .||. ..|  | .. | .   .  . . .     || |      .
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIKFMDMH--YDHDRCSKNPYYDNLHPSFYM

VMDYLPLSLHQFNMNYRKERKYPPLLY---VKLFAFQMFAGLNYIHSIGVTHRDLKPQNILCDMES----GELKICDFGSAKQLV-------------PG
||.| |  .     |  .   |.  |    .. |. ||. |..|.|. .  |||.|||||. .         ||| |||.|                 |.
VMEYMPYTW----YNQLHNNRYN--LSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPM

EKSVSYIASRYYRAPELIFDCVYYTSAIDIWAGACVVAEMLMAGMPIFAGGSSLGQLHEIVKVLGPPTEDD
 . .. .. | |||||| |    |. ..|||. .|..||..  | |||.| . . |.| | |.|| |.||.
QQYSTQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQ-GKPIFQGRTEIEQMHHIFKMLGTPCEDM
Kinase 87414.m00318.AA CDKL 146-328 35 5.9e-43 144.69 In-house 100-286 (286) Show / Hide 
Range on Protein: 146-328
Range on HMM: 100-286/286
Sequence Identity: 35% (68 aa)

VKLFAFQMFAGLNYIHSIGVTHRDLKPQNILCDMESGELKICDFGSAKQLV-PGEKSVSYIASRYYRAPELIFDCVYYTSAIDIWAGACVVAEMLMAGMP
|.   .|   ..|. |.  . ||| || |||    .|..|.|||| |..|  |||    | | | ||||||  . . | ...|||| .||.|||.. | |
VRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMID-GQP

IFAGGSSLGQLHEIVKVLGPPTEDDMNSFQ-----HGADIPLSSNPGIGLENVLPRHTPPDIMDLLKSIFIYNPSKRPTALECIKHPCF
.. | | . ||. |.|.||| . . .. |      ||  .|  ...   ||  .|    .  .|..|. .  .|..|.|. .. .|| |
LWPGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIEHM-EPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase 87414.m00318.AA ERK 149-328 36 1.3e-40 141.28 In-house 113-307 (307) Show / Hide 
Range on Protein: 149-328
Range on HMM: 113-307/307
Sequence Identity: 36% (72 aa)

FAFQMFAGLNYIHSIGVTHRDLKPQNILCDMESGELKICDFGSAKQLVPGEKSV---------SYIASRYYRAPELIFDCVYYTSAIDIWAGACVVAEML
|  |.  || |||| .| |||||| |||.  . . ||||||| |  . ..  .           |.|.|.|||||..     ||.|.|||.  |  ||||
FMYQILCGLKYIHSANVIHRDLKPSNILVN-SNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEML

MAGMPIFAGGSSLGQLHEIVKVLGPP-TEDDMNSF------QHGADIPLSSNPGIGLENVLPRHT-PPDIMDLLKSIFIYNPSKRPTALECIKHPCF
. . |.| |.....|. .| ...| | .|.|.. .      .     |    |.. .||. |..   |.  |||..    .|.|| |. ||..|| |
G-RKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase 87414.m00318.AA ERK7 151-328 33 2.8e-40 135.29 In-house 107-292 (292) Show / Hide 
Range on Protein: 151-328
Range on HMM: 107-292/292
Sequence Identity: 33% (64 aa)

FQMFAGLNYIHSIGVTHRDLKPQNILCDMESGELKICDFGSAKQLVPGEK-------SVSYIASRYYRAPELIFDCVYYTSAIDIWAGACVVAEMLMAGM
.|..  . |.||  | |||||| ||| | |   .|.|||| |  .   |.          |.| | |||||       || ..| |   |...|||  | 
YQLLRAIKYMHSGNVIHRDLKPSNILLDSEC-MVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLR-GK

PIFAGGSSLGQLHEIVKVLGPPTEDDMNSFQHGADI----PLSSNPGIGLENVLPRHTPPDIMDLLKSIFIYNPSKRPTALECIKHPCF
|.|.| | . |.  |..... ||. |... .    .     . ...   |....| ....| .|||| . ..|| || || ....||  
PMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMP-QCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase 87414.m00318.AA CDC2 45-269 30 8.9e-40 119.57 In-house 1-232 (301) Show / Hide 
Range on Protein: 45-269
Range on HMM: 1-232/301
Sequence Identity: 30% (74 aa)

YRPIKVIGQGAFGIVYCARAVD-GSIVAIKKVLLDPRYKN--------RELETMQEIN-NRYCIRLCSAFKTPGRKPKEYYLNLVMDYLPLSLHQFNMNY
|  |. || | .|.|| .. .. . |||.||. |.             ||. ...|..     ..|   ..        . | .| .||   | ..  ..
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-------NKLYMVFEYLDMDLKKYMDMS

RKERKYPPLLYVKLFAFQMFAGLNYIHSIGVTHRDLKPQNILCDMESGELKICDFGSAKQL-VPGEKSV--SYIASRYYRAPELIFDCVYYTSAIDIWAG
 . .|. |. .|| ...|.  |... |. .. |||||||||| | ..|..|| ||| |.   .|  .      .  . |||||. . | .|. ..|.|. 
IPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILID-KKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSI

ACVVAEMLMA--GMPIFAGGSSLGQLHEIVKVLGPPTEDD
 |. ||| |     |.|.| |   ||  | ..|| |.|..
GCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQT
Kinase 87414.m00318.AA TyrKc 45-328 22 5.2e-14 3.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 45-328
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

YRPIKVIGQGAFGIVYCARAVDGSIVAIKKVLLDPRYKN--RELETMQEI--NNRYCIRLCSAFKTPGRKPKE---YYLNLVMDYLPL-SLHQFNMNYRK
 . .|..| ||||.|| ...     ||.|..  |   .   ||.. | ..  ..   .||  .  ..||.        | .|| | |. .|...  ..|.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKHRP

ERKYPPLLYVKLFAFQMFAGLNYIHSIGVTHRDLKPQNILCDMESGELKICDFGSAKQLVPG----EKSVSYIA-----SR-----YYRAPELIFDCVYY
.    ..     |..|  .| .|.|| .. ||||   |.| . .    ||.||| .. .  .    | .  | .     ..        ||| |.... .
K---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-F

TSAIDIWAGACVVAEMLMAGMPIFAGG----SSLGQLHEIVKVL-GPPTEDD---MNSFQHGADIPLSSNPGIGLENVLPRHTPPDIMDLLKSIFIYNPS
|.. |.|.   .  |..  |..   |      |  ...| ||    .|  ..   |                         . |... .. |.   ..|.
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------F-VCCPDEMYQIMKQCWHEDPE

KRPTALECIKHPCF
.|||  |.  | ||
DRPTFSEI--HECF
Kinase 87414.m00318.AA MAPK 45-75 42 4.1e-08 23.93 In-house 1-38 (328) Show / Hide 
Range on Protein: 45-75
Range on HMM: 1-38/328
Sequence Identity: 42% (16 aa)

YRPIKVIGQGAFGIVYCARAVD-------GSIVAIKKV
|...| |||||.|.|  |. .        | .|||||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKI
Kinase 87414.m00318.AA CDC2 285-328 28 1e-07 19.26 In-house 250-301 (301) Show / Hide 
Range on Protein: 285-328
Range on HMM: 250-301/301
Sequence Identity: 28% (15 aa)

PGIGLENVLPR--------HTPPDIMDLLKSIFIYNPSKRPTALECIKHPCF
. ..|....|.         ..|. .|||... .|.|.|| .| | ..|| |
KPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 87414.m00318.AA RCK 45-94 33 3.4e-07 18.55 In-house 1-44 (298) Show / Hide 
Range on Protein: 45-94
Range on HMM: 1-44/298
Sequence Identity: 33% (17 aa)

YRPIKVIGQGAFGIVYCARAVD-GSIVAIKKVLLDPRYKNRELETMQEINN
|  || .| |..| |  |.... | ||||||         ..... .|..|
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-------QKFYSWEECMN
Kinase 87414.m00318.AA ERK 45-75 43 1.7e-05 16.69 In-house 1-37 (307) Show / Hide 
Range on Protein: 45-75
Range on HMM: 1-37/307
Sequence Identity: 43% (16 aa)

YRPIKVIGQGAFGIVYCARAVD------GSIVAIKKV
|. || ||.||.|.|  |.         | .|||||.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKI
Kinase 87414.m00318.AA Pkinase_Tyr 45-75 30 0.000213 15.52 Pfam 1-36 (270) Show / Hide 
Range on Protein: 45-75
Range on HMM: 1-36/270
Sequence Identity: 30% (11 aa)

YRPIKVIGQGAFGIVYCARAV-----DGSIVAIKKV
 . .|..|.|||| || ...      ..  ||.|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML
Kinase 87414.m00318.AA ERK7 45-75 40 0.00101 8.25 In-house 1-32 (292) Show / Hide 
Range on Protein: 45-75
Range on HMM: 1-32/292
Sequence Identity: 40% (13 aa)

YRPIKVIGQGAFGIVYCARAV-DGSIVAIKKV
|  .| .|.||.|||  |     . .||.||.
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKI
Kinase 87414.m00318.AA CDK-Unclassified 311-328 38 0.009592 4.7 In-house 307-324 (324) Show / Hide 
Range on Protein: 311-328
Range on HMM: 307-324/324
Sequence Identity: 38% (7 aa)

YNPSKRPTALECIKHPCF
|.| .|... |  .|| |
YQPYNRWKCMEILQHPWF
Kinase 87414.m00318.AA CDKL 45-74 41 0.018168 4.25 In-house 1-31 (286) Show / Hide 
Range on Protein: 45-74
Range on HMM: 1-31/286
Sequence Identity: 41% (13 aa)

YRPIKVIGQGAFGIVY-CARAVDGSIVAIKK
|  . ..| |. | |. |     | ||||||
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKK
Kinase 87414.m00318.AA Pkinase_Tyr 149-230 28 0.061317 7.19 Pfam 116-199 (270) Show / Hide 
Range on Protein: 149-230
Range on HMM: 116-199/270
Sequence Identity: 28% (25 aa)

FAFQMFAGLNYIHSIGVTHRDLKPQNILCDMESGELKICDFGSAKQL-------VPGEKSVSYIASRYYRAPELIFDCVYYTSAIDIWA
...|  .|..| .|..  ||||   |.| . |..  |||||| |. .       . ....   .  . . ||| |.... .|.. |.|.
MCWQIAKGMEYLESKNCIHRDLAARNCLVT-ENNVVKICDFGLARDIYNDDYYYRKRGGGK--LPIKWM-APECINYGK-FTTKSDVWS
Kinase 87414.m00318.AA Pkinase_Tyr 294-328 37 2.221026 1.91 Pfam 238-270 (270) Show / Hide 
Range on Protein: 294-328
Range on HMM: 238-270/270
Sequence Identity: 37% (13 aa)

PRHTPPDIMDLLKSIFIYNPSKRPTALECIKHPCF
|...|..| ||.|.   |.|..|||  |.  | ..
PENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL