Gene 85889.m00444 (T.vaginalis)

85889.m00444

Species: T.vaginalis
Alias: 85889.m00444, TvagK0587
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
85889.m00444.AA Protein None 284 None Fasta, JSON
85889.m00444.kin_dom Protein Kinase Domain None 277 None Fasta, JSON

Protein domain

Protein domains of 85889.m00444.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85889.m00444.AA CDK 2-278 41 1.1e-130 420.35 In-house 1-284 (284) Show / Hide 
Range on Protein: 2-278
Range on HMM: 1-284/284
Sequence Identity: 41% (129 aa)

YTKLNRIGQGTYGVVYKAQNTQNK-----EIVAIKRIKFESQ----E-EGIPSTAIREIALLKELKHPNIVQLYDVVHSQ-----------HTLTLIFEY
| ||..||.|||||||||...|..     .|||.|.|. |..    | ||.|.||||||.||||| |||||.|.||.|.            ..|...|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CDWDLRRYMQSKNNMLSQEEIISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGE-----LKLADFGLARSTFI------PVDSLSTEVITRWYRPPE
.|.||  ||           | .. .||||.|...||. |.||| ||||||.|..||     ||.|||||||   |      |.  .. ||.|.|||.||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

ILLGNQNYG--FPVDVWSAGCVIVEMIT---GQPLFQCASNEELMEKVTVLFGSEAVERAFPEIKKQSDVLQPVGLQNIIPNTNPELLQLVLALLEVDPS
.||| ..|.   |.|.||.||...||.|   ..|||.. |  . ..|.  ..|.   |   |...|  |                   .|   .|  ||.
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGT-PTEDNWPGVTKLPDY------------------DLLNKMLCYDPK

KRISAADSLKLPIF
||||| . |. | |
KRISAEQALQHPYF
Kinase 85889.m00444.AA CDK5 2-278 46 1.3e-128 408.68 In-house 1-287 (287) Show / Hide 
Range on Protein: 2-278
Range on HMM: 1-287/287
Sequence Identity: 46% (133 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIKFESQEEGIPSTAIREIALLKELKHPNIVQLYDVVHSQHTLTLIFEYCDWDLRRYMQSKNNMLSQEEI
| |...|| ||||.||||.| . .||||.||.. .|  ||.||||||||.|||||||.||| |.||.||   |||.||.|| ||..|| | |  .... |
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

ISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLARSTFIPVDSLSTEVITRWYRPPEILLGNQNYGFPVDVWSAGCVIVEMI-TGQPLF
 || ||||. |.| |.. . ||| |||| | |..||||||||||||   |||   | ||.| ||||| .|.| . |  ..|.||.||.. ||. .|.|||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

QCASNEELMEKVTVLFGSEAVER-----AFPEIK---KQSDVLQPVG-LQNIIPNTNPELLQLVLALLEVDPSKRISAADSLKLPIF
  .. |. . ..  . |.  ...       |. |   .| .. ..   .|.|.|. . ... |   .|...| .||||.. |. | |
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 85889.m00444.AA CDC2 2-201 51 2.7e-122 377.84 In-house 1-210 (301) Show / Hide 
Range on Protein: 2-201
Range on HMM: 1-210/301
Sequence Identity: 51% (108 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIKFESQEEG--IPSTAIREIALLKELK-HPNIVQLYDVVHSQHTLTLIFEYCDWDLRRYMQ---SKNNM
|.|...|| ||||||||....| ..|||.|.|. |...||  .|||||||| .||||| |||||.| ||.|. . | ..|||.| ||..||    .||  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LSQEEIISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLARSTFIPVDSLS--TEVITRWYRPPEILLGNQNYGFPVDVWSAGCVIVEM
.... . |. ||.|....| |.. |.||| ||||||...||..|.|||||||   ||.. .    ||.|.|||.|||||| . | .|||.|| ||.. ||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---ITGQPLFQ
   .|  |||.
FMDVTKKPLFH
Kinase 85889.m00444.AA CMGC 2-278 24 5.8e-121 399.51 In-house 1-513 (513) Show / Hide 
Range on Protein: 2-278
Range on HMM: 1-513/513
Sequence Identity: 24% (125 aa)

YTKLNRIGQGTYGVVYKAQN--------------TQNKEIVAIKRIK---FESQ------EEGIPSTAIREIALLKELK-----------------HPNI
|.....||.||||||||...              ....||||||.||   .| |      ..|.|..|.||| .||.|.                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VQLYDVVHSQH-----------------TLTLIFEYCDWDLRRYMQSKNN--------MLSQEE------------IISFS------YQLLRALE--FIH
|.|||.... .                  | |.|||.|.|| .|......         ||. .            | .|.      ||.||.|.  ..|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SKY--IIHRDVKPQNILLNRKGEL--------------------KLADFGLARSTFIP---------------------VDSLSTEVITRWYRPPEILLG
|.   ||||| ||.|||.| ..||                    |..||||||.. ..                     .  ....| |||||.||||||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

N---------QNYGFPVDVWSAGCVIVEMITG--------QPLFQCASN-----------EELMEKVTVLFGSEA--------------VERAFPEIKK-
          ..|. |.|.||.||.. ||.||        .|||.  |.            . ..|   ..|.                 |. .|...| 
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

------------------QSD-------------VLQPVGLQNIIPN-----------------------------------TNPELLQLVLALLEVDPS
                  .|.               .|  ..|..|.                                    .|... |.  .|. ||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRISAADSLKLPIF
|||.|.. |. | |
KRITAEQALQHPYF
Kinase 85889.m00444.AA S_TKc 2-278 32 3.8e-99 336.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 2-278
Range on HMM: 1-231/231
Sequence Identity: 32% (95 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIKFESQEEGIPSTAIREIALLKELKHPNIVQLYDVVHSQHTLTLIFEYCDW---DLRRYMQSKNNM---
|..|. ||.|..|.|||....  ..|||||.||          ...|||..||. .|||||.|||| .. . | ...||||    ||..|.....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSQEEIISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLARSTFIPVDSLSTEVITRWYRPPEILLGNQNYGF-PVDVWSAGCVIVE
  ..  .. .. ||...|||..||. |||||.||.||||..  ..|..||||||         .| . |.||..||.|     ||. ..|.|| ||.. |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MITGQPLFQCASNEELMEKVTVLFGSEAVERAFPEIKKQSDVLQPVGLQNIIPNTNPELLQLVLALLEVDPSKRISAADSLK-------LPIF
|..|.|.|.   ....| |. .                                  ||.....  .|..||.||..| . |.        | |
MLCGYPPFP---QMQMMFKKIG---------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85889.m00444.AA PFTAIRE 2-278 39 1.4e-97 330.51 In-house 1-287 (287) Show / Hide 
Range on Protein: 2-278
Range on HMM: 1-287/287
Sequence Identity: 39% (115 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIKFESQEEGIPSTAIREIALLKELKHPNIVQLYDVVHSQHTLTLIFEYCDWDLRRYMQSKNNMLSQEEI
| ||.. | |.|  |||.    |. .|| | |. . |||| | |||||  |||.||| ||| | |..| . |||..||| . ||  || . .. .  . .
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

ISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLARSTFIPVDSLSTEVITRWYRPPEILLGNQNYGFPVDVWSAGCVIVEMITGQPLFQ
  | .|||| | ..| ... |||.|||| |.  .||||||||||||   .|    | ||.| ||||| .|||  .|   .|.| .||. |||..|||.| 
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP

CA-SNEELMEKVTVLFGSEAVER-----AFPEIKKQSDV---LQPVGLQNIIPNTN--PELLQLVLALLEVDPSKRISAADSLKLPIF
      . .||.  . |.   ..      .|. |..       .|  |....|     |.  .|.  .| . | .|.||.. .. | |
GMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase 85889.m00444.AA CDK7 2-194 42 1.7e-92 246.62 In-house 1-197 (288) Show / Hide 
Range on Protein: 2-194
Range on HMM: 1-197/288
Sequence Identity: 42% (84 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIK-FESQEE---GIPSTAIREIALLKELKHPNIVQLYDVVHSQHTLTLIFEYCDWDLRRYMQSKNNMLS
|.|.  || |....||||. .|  .|||||.||   ...|   ||  |||||| .|.|..|.|.. | |.   .  . |.|.. ||||      |   | 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

QEEIISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLARSTFIPVDSLSTEVITRWYRPPEILLGNQNYGFPVDVWSAGCVIVEMI
. .| ..  ..|. ||. |  .| ||| || | |.|  |.||.|||||||.   |   ..  |.||||| || | |   ||  ||.|| ||.. | .
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELM
Kinase 85889.m00444.AA Pkinase 2-278 31 1.3e-88 305.45 Pfam 1-293 (293) Show / Hide 
Range on Protein: 2-278
Range on HMM: 1-293/293
Sequence Identity: 31% (96 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIKFESQEEGIPSTAIR--EIALLKELKHPNIVQLYDVVHSQHTLTLIFEYCDW-----DLRRYMQ-SKN
|... .||.|..|.|||...  . .|||.|.|| ...... . |..|  ||...|.|.|||||.|||....   . ...|||.      || .|.. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NML--SQEEIISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGEL----KLADFGLARST-FIPVDSLSTEVITRWYRPPEILLGNQNYGFPVDVWSA
. .  | .|.... ||.||.||..||. |||||.||.|||....|..    |..|||||.     .   ..| . |.||..||...|.| || .||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVIVEMITGQPLFQCAS----NEELMEKVTVLFGSEAVERAFPEIKKQS-----DVLQPVGLQNIIPNTNPELLQLVLALLEVDPSKRISAADSLKLPI
||.. ||..|.|.|.  .    |   . .. .. ..  ... .|.    |     .   .  ..   .|...|.....  .|..||.||..|.. |. | 
GCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase 85889.m00444.AA PCTAIRE 2-200 51 1.7e-87 297.0 In-house 1-198 (291) Show / Hide 
Range on Protein: 2-200
Range on HMM: 1-198/291
Sequence Identity: 51% (102 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIKFESQEEGIPSTAIREIALLKELKHPNIVQLYDVVHSQHTLTLIFEYCDWDLRRYMQSKNNMLSQEEI
|.||.. | |||  ||| .      .|| | |. |  ||| | |||||. |||.||| ||| | |..| .| |||.||| | ||..||    |...  ..
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNV

ISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLARSTFIPVDSLSTEVITRWYRPPEILLGNQNYGFPVDVWSAGCVIVEMITGQPLF
  | .|||| | . | . | ||| |||| |.| .||||||||||||   .|    | ||.| |||||..|.|. .|  ..|.|  ||.  || ||.|||
KLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLF
Kinase 85889.m00444.AA PITSLRE 2-278 37 2.7e-79 269.72 In-house 1-295 (295) Show / Hide 
Range on Protein: 2-278
Range on HMM: 1-295/295
Sequence Identity: 37% (110 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIKFE--SQEEGIPSTAIREIA-LLKELKHPNIVQLYDVV--HSQHTLTLIFEYCDWDLRRYMQSKN---
. .||||. |||||||.|....  ||||.||.| |     ||.| |..|||  .|..|.|||||..  .|         ...|| . ||.  |   .   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

NMLSQEEIISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLARSTFIPVDSLSTEVITRWYRPPEILLGNQNYGFPVDVWSAGCVIVEM
   .  || ..  ||||. |. |.. |.||| |  |.|.. || ||..||||||    |. ...  |.| ||| ||.||| . |  |||.|| ||.  |.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

ITGQPLFQCASNEELMEKVTVLFG--SEAV---ERAFPEIKKQS-DVLQPVG-LQNIIP---NTNPELLQLVLALLEVDPSKRISAADSLKLPIF
||..||||  |  . ....  ..|  .|        .|  |.   .  .|.. | ...|    ..   . |   .|. .| .||.| | || | |
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase 85889.m00444.AA MAPK 2-201 35 2.9e-75 256.37 In-house 1-236 (328) Show / Hide 
Range on Protein: 2-201
Range on HMM: 1-236/328
Sequence Identity: 35% (86 aa)

YTKLNRIGQGTYGVVYKAQNTQ------NKEIVAIKRIK--FESQEEGIPSTAIREIALLKEL-KHPNIVQLYDVVHS-----QHTLT------LIFEYC
|. | .|||| |||| .|  .       ....||||.|   |...       ..||| ||... .|.||. |.|. .      |..|       ...|..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK--RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELM

DWDLRRYMQSKNNMLSQEEIISFSYQLLRA--LEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLAR----STFIPVD----------SLSTEVITRWY
..||.. ..| . .|| . | .| ||.||.  | .|||  .|||| || |||.|  ..||..||||||    ... . .           ..  | ||||
ETDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWY

RPPEILLG--NQNYGFPVDVWSAGCVIVEMIT-GQPLFQ
| |||.|.   ..|   ||.||.||   ||.| ..|||.
RAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFP
Kinase 85889.m00444.AA CDKL 2-200 43 2e-73 250.26 In-house 1-200 (286) Show / Hide 
Range on Protein: 2-200
Range on HMM: 1-200/286
Sequence Identity: 43% (88 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIKFESQEEGIPSTAIREIALLKELKHPNIVQLYDVVHSQHTLTLIFEYCDWDLRRYMQSKNNMLSQEEI
| || ..| | ||||.|  |  . .|||||. |    .. .  .| ||| .|| |||.|||.|  |      | | |||||  .  . . . | . .. .
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

ISFSYQLLRALEFIHSKYIIHRDVKPQNILLN-RKGELKLADFGLARSTFI-PVDSLSTEVITRWYRPPEILLGNQNYGFPVDVWSAGCVIVEMITGQPL
 .  .|.|.|..| |.  .||||.|| |||.. ..|..|| |||.|| .   | . .   | ||||| || |.|   || |||.|..|||. |||.||||
RKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPL

F
.
W
Kinase 85889.m00444.AA Pkinase_Tyr 2-212 28 2.6e-31 106.69 Pfam 1-228 (270) Show / Hide 
Range on Protein: 2-212
Range on HMM: 1-228/270
Sequence Identity: 28% (68 aa)

YTKLNRIGQGTYGVVYKAQNT----QNKEIVAIKRIKFESQEEGIPSTA------IREIALLKEL-KHPNIVQLYDVVH-SQHT--LTLIFEYCDW-DLR
 |..  .|.| .|.|||.  .    ..|  ||.| .|     ||  . .      .||....|.| .|||||.|| |.   .    . ...||.   ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

RYMQSK---NNMLSQEEIISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLARSTFIPVDSLSTEVIT------RWYRPPEILLGNQNY
 | ...   .. |. ........|  ...|. .|| .||||.   |.|.....  | .||||||    . |   . . .      .|. .|| .  .  .
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWM-APECINYGK-F

GFPVDVWSAGCVIVEMIT-G-QP-LFQCASNEELMEKV
    |||| | .. |..| | ||    . ||||..|..
TTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYI
Kinase 85889.m00444.AA TyrKc 2-278 24 1.6e-22 82.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-278
Range on HMM: 1-280/280
Sequence Identity: 24% (75 aa)

YTKLNRIGQGTYGVVYKAQNTQNKEIVAIKRIKFESQEEGIPSTAIREIALLKEL--KHPNIVQLYDVVHSQ-------HTLTLIFEYCDW-DLRRYMQS
 |..  .| | .|.|||.. .   . ||.| .| ..         .||. ....|  .|||||.|| |. .|       . | ...||... ||. | ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KNNMLSQEEIISFSYQLLRALEFIHSKYIIHRDVKPQNILLNRKGELKLADFGLARSTFIP--------VDSL----STE--VITRWYRPPEILLGNQN-
. . |. .. .||..|  .  |..||| .||||    |.|.....  | .||||.|             . .     ..   .  ||. .|| .  | . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI--NYGK

YGFPVDVWSAGCVIVEMIT-GQPLFQC-----ASNEELMEKVTVLFGSEAVERAFPEIKKQSDVLQPVGLQNIIPNTNPELLQLVLALLEVDPSKRISAA
. .  |||| | .. |. | ||.          ||.|..|.|   .  .  . . | .                .   .|. |. .   . ||..| . .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS-------------F-VCCPDEMYQIMKQCWHEDPEDRPTFS

DSLKLPIF
.     .|
EI--HECF
Kinase 85889.m00444.AA CDK7 250-278 34 1.3e-08 18.58 In-house 260-288 (288) Show / Hide 
Range on Protein: 250-278
Range on HMM: 260-288/288
Sequence Identity: 34% (10 aa)

ELLQLVLALLEVDPSKRISAADSLKLPIF
.|| |.  ..  .|.||......|| | |
DLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 85889.m00444.AA CDKL 245-278 25 9.3e-08 22.61 In-house 252-286 (286) Show / Hide 
Range on Protein: 245-278
Range on HMM: 252-286/286
Sequence Identity: 25% (9 aa)

PNTN-PELLQLVLALLEVDPSKRISAADSLKLPIF
|| . ...| .. ..|. ||..|........ |.|
PNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase 85889.m00444.AA CDC2 236-278 36 1.2e-07 19.07 In-house 250-301 (301) Show / Hide 
Range on Protein: 236-278
Range on HMM: 250-301/301
Sequence Identity: 36% (19 aa)

QPVGLQNIIPN---------TNPELLQLVLALLEVDPSKRISAADSLKLPIF
.| .|..|.||         ..|| ..|   .|  ||.||||| . |. | |
KPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 85889.m00444.AA MAPK 236-278 29 2e-06 17.84 In-house 282-328 (328) Show / Hide 
Range on Protein: 236-278
Range on HMM: 282-328/328
Sequence Identity: 29% (14 aa)

QPVGLQNIIPN----TNPELLQLVLALLEVDPSKRISAADSLKLPIF
... .....||    .||. . |.  .|. ||.|||.... |  | |
PKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 85889.m00444.AA PCTAIRE 253-278 34 0.001912 7.92 In-house 266-291 (291) Show / Hide 
Range on Protein: 253-278
Range on HMM: 266-291/291
Sequence Identity: 34% (9 aa)

QLVLALLEVDPSKRISAADSLKLPIF
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DLLTMLLQYESKNRVSAEKAMKHPYF