Gene 90729.m00113 (T.vaginalis)

90729.m00113

Species: T.vaginalis
Alias: TvagK0836, 90729.m00113
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK8-like

Sequence

Name Sequence Type Origin Length Description Download
90729.m00113.AA Protein None 354 None Fasta, JSON
90729.m00113.kin_dom Protein Kinase Domain None 310 None Fasta, JSON

Protein domain

Protein domains of 90729.m00113.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90729.m00113.AA CMGC 12-321 21 1.8e-90 297.41 In-house 1-513 (513) Show / Hide 
Range on Protein: 12-321
Range on HMM: 1-513/513
Sequence Identity: 21% (111 aa)

YTLLKKVGSGTYGEVFKA-------------SAIGDPTKIVSVKQSKQTKNGNDDKL-------IPPAVLRELTLLSEIN----------------FPH-
|. .||.|.||||.|.|.              .  .  .|| .|  |. .   ....       .|   |||. .| ..|                 .. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIHTSIKDVFYDSDNH---------------VLAFVYDYGAFDVRKLIRFYLS-----RKQIVSEMV------------TKSIL------FQLLLALD--
|..  ..|.||.....                | .| .|   |  ..|. .       |..  || .             |...      .|.| .|.  
IVK--LYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLK

HIHQRG--IIHCDITPPNLIIMPENSK---------------IPGIVKLIDFGLARAIDNT---------------------NFPKNTGVVTVWYRAPEL
..|...  |||.|. | |. | ...                   |..|..||||||....                      | |  . ||| ||||||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

LLGDSHYD---------ASIDLWSAGCIFAELLLG--------DVLFKAETQN---EQNPTGFNKNQLAKILEIMGPINESSIAR----------PE---
|||..||.          .|| ||.||||||...|        . ||. .. .     .    . .||.|| ...|... . | .          .|   
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDD-KNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWP

-----------------------WCAHLADYNRM---TKPKQKTSLQKLFQN-----------------------------------VNPKAFDLLIKML
                       |. .   | ..    ..... ....|| .                                    .|.|.||| |||
NMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKML

EYNPYHRITAHDALRHEYF
.|.|  |||| .||.|.||
QYDPDKRITAEQALQHPYF
Kinase 90729.m00113.AA CDK 12-321 31 1.6e-75 241.09 In-house 1-284 (284) Show / Hide 
Range on Protein: 12-321
Range on HMM: 1-284/284
Sequence Identity: 31% (105 aa)

YTLLKKVGSGTYGEVFKASAIGD----PTKIVSVKQSKQTKN--GNDDKLIPPAVLRELTLLSEINFPHIIHTSIKDVFYDSD---------NHVLAFVY
|  |.|.| ||||.|.||    .    . .||  |. .  ..   ...  .|   .|| .|| |.  |.|.   ..||.....         .. | .| 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVK--LHDVCHTKNMDRNNKDKHENKLYMVF

DYGAFDVRKLIRFYLSRKQIVSEMVTKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENS-KIPGIVKLIDFGLARAIDN------TNFPKNTGVVTV
.|   |  |...              |....||| .|...|...|.| |. | |. |.   . | .| .|. |||||||  .       | .    ||| 
EYMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVK-CGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTL

WYRAPELLLGDSHYD--ASIDLWSAGCIFAELLL---GDVLFKAETQNEQNPTGFNKNQLAKILEIMGPINESSIARPEWCAHLADYNRMTKPKQKTSLQ
||||||||||..||.   .||.||.||||||...   .  ||  ..           .|| || .|.|  .|..      . .| ||             
WYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSE---------IDQLFKIFRICGTPTEDNWPG---VTKLPDY-------------

KLFQNVNPKAFDLLIKMLEYNPYHRITAHDALRHEYF
           ||| ||| |.|..||.| .|| |.||
-----------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 90729.m00113.AA S_TKc 12-321 24 1.5e-71 244.9 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-321
Range on HMM: 1-231/231
Sequence Identity: 24% (79 aa)

YTLLKKVGSGTYGEVFKASAIGDPTKIVSVKQSKQTKNGNDDKLIPPAVLRELTLLSEINFPHIIHTSIKDVFYDSDNHVLAFVYDYGAF---DVRKLIR
|..|.|.|.|..|.|.|.  ..   .|| .|. |              ..||. .|.. . |.|..  ..|||.|   . | .| .|      |....|.
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------------EHIRREIQILKK-HHPNIVK--LYDVFQD---DHLYMVMEYCDGDLGDLFDYIK

FYLSRK--QIVSEMVTKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENSKIPGIVKLIDFGLARAIDNTNFPKNTGVVTVWYRAPELLLGDSHYDA-
 . ...  .  .| ...... |...||...|..||||.|. | |. .          .|..|||||| .       .| ..| ||.|||.|    .|.  
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKC

SIDLWSAGCIFAELLLGDVLFKAETQNEQNPTGFNKNQLAKILEIMGPINESSIARPEWCAHLADYNRMTKPKQKTSLQKLFQNVNPKAFDLLIKMLEYN
..| || |||..|.| |  .|                |........|                                       | | |.. |.|...
KCDWWSCGCILYEMLCGYPPFP---------------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKD

PYHRITAHDALR-------HEYF
| .|.|| .||.       |..|
PEKRPTA-EALQDEWDIKCHPWF
Kinase 90729.m00113.AA CDK8 16-321 29 8.2e-65 201.96 In-house 1-329 (329) Show / Hide 
Range on Protein: 16-321
Range on HMM: 1-329/329
Sequence Identity: 29% (99 aa)

KKVGSGTYGEVFKASAIGD---PTKIVSVKQSKQTKNGN---DDKLIPPAVLRELTLLSEINFPHIIHTSIKDVFYDSDNHVLAFVYDYGAFDVRKLIRF
| .|.|||| |.||        |.| . .|| . .|.|    . . |     ||  |. |   |..|  .  .||       .  ..||  .|    |.|
KYIGRGTYGHVYKAKRKKQKKKPNKEYALKQFRTEKDGVEQLEGTGISMSACREIALCRELHHPNVI--CLQRVFLNHKDKCVWMLFDYAEHDLWHIIKF

YLSRKQIVSEMV------TKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENSK-IPGIVKLIDFGLARAIDNTNFPKNTG---VVTVWYRAPELLLG
    |   .. .       |||..|.|      |.  ..| |  | | ..| . .  . | ||  |.|.||   |   | ...   |||.||||||||||
HRHNKAHMKDPTMVPRNMVKSIMWQILDGIHYLHSNWVLHRDLKPANIMVMGDGPEDMCGCVKIADMGFARIFHNPLKPLYDLDPVVVTFWYRAPELLLG

DSHYDASIDLWSAGCIFAELLLGDVLFKAETQ--NEQNPTGFNKNQLAKILEIMGPINESSIARPEWCAHLADYNRMTK-----PKQKT-SLQKLFQ---
  ||   ||.|. |||||||.    .|. . .      .  .  .|| .|...||     . .  .   .. .. |..|     ..  . || . .    
ARHYTKAIDIWAIGCIFAELITSEPIFHCKEEKLDIKTQNPYHHDQLDRIFHVMG---FPQDKMWPDIKKMPEHQRLMKDFRRMQTYPNCSLHWYMEKHK

-NVNPKAFDLLIKMLEYNPYHRITAHDALRHEYF
 . . .|..|| ||| . |  |||. .|. | ||
IKRDSHAYHLLYKMLTMDPTKRITCEQAMEHPYF
Kinase 90729.m00113.AA Pkinase 12-321 28 7.3e-63 219.96 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-321
Range on HMM: 1-293/293
Sequence Identity: 28% (91 aa)

YTLLKKVGSGTYGEVFKASAIGDPTKIVSVKQSKQTKNGNDDK-----LIPPAVLRELTLLSEINFPHIIHTSIKDVFYDSDNHVLAFVYDYGAFDVRKL
|....|.|||..|.|.|.  .|..  || ||. |  ..  . .     |      .|. .. ..| |.|    ..|.|.| ..|.  .| .|   ..  .
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRL------SEIQIMKRLNHPNI--VRLYDWFED-KDHIY-MVMEYCEGGLY-V

IRFY--LS--RKQIV--SEMVTKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENSKIPGIVKLIDFGLARAI-DNTNFPKNTGVVTVWYRAPELLLG
.  .  .|  |.  .  || . |... |.| .|...|..||||.|. | |. |  .|  |. .||..|||||. .    |   .| ..| ||.|||...|
MDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

DSHYDASIDLWSAGCIFAELLLGDVLFKAETQNEQNPTGFNKNQLAKILEIMGPINESSIARPEWCAHLADYNRMTKPKQKTSLQKLFQNVNPKAFDLLI
...|. ..| ||.|||..|.|.|  .|. .  .. |      .|...| .||||......  |.||    .. ... .   . ....  |... . |.. 
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-H----DQMQMICRIMGPPLHFDW--PWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIK

KMLEYNPYHRITAHDALRHEYF
..|...|. |.||...| |..|
WCLCKDPKKRPTAEQILQHPWF
Kinase 90729.m00113.AA CDK5 12-321 34 1.7e-59 186.47 In-house 1-287 (287) Show / Hide 
Range on Protein: 12-321
Range on HMM: 1-287/287
Sequence Identity: 34% (109 aa)

YTLLKKVGSGTYGEVFKASAIGDPTKIVSVKQSKQTKNGNDDKLIPPAVLRELTLLSEINFPHIIHTSIKDVFYDSDNHVLAFVYDYGAFDVRKLIRFYL
|  . |.| |||| |.||    .   ||     |. .  ..|  .| . .||  || |.  . |.   . ||   |..  |  |. .   | .|   .  
YEKMEKIGEGTYGTVYKARNK-ETHEIVAL---KRVRLDSEDEGVPSTAIREICLLKELKHKNIVR--LHDVIH-SEKK-LTLVFEFCDQDLKK---YMD

SRKQIVSEMVTKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENSKIPGIVKLIDFGLARA--IDNTNFPKNTGVVTVWYRAPELLLGDSHYDASIDL
|..  ..  . ||...|||  |   |.. . | |  | || |  .     |. || |||||||  |   ..     ||| |||.|  |.|  ||  |||.
SCNGEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKN-----GELKLADFGLARAFGIPVRCYSHE--VVTLWYRPPDVLMGSKHYSTSIDM

WSAGCIFAELL-LGDVLFKAETQNEQNPTGFNKNQLAKILEIMGPINESSIARPEW--CAHLADYN----RMTKPKQKTSLQKLFQNVNPKAFDLLIKML
||.||||||.   |  ||         |    ..|| .| .|||  .|..     |   ..| ||.       .   ..|.|.. .. . |  ||| |||
WSCGCIFAEMANAGRPLF---------PGNDVEDQLKRIFKIMGTPCEDK-----WPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKML

EYNPYHRITAHDALRHEYF
..|| .||.| .||.| ||
QCNPNQRISAKAALHHPYF
Kinase 90729.m00113.AA CDC2 12-234 32 1.8e-54 165.53 In-house 1-217 (301) Show / Hide 
Range on Protein: 12-234
Range on HMM: 1-217/301
Sequence Identity: 32% (74 aa)

YTLLKKVGSGTYGEVFKASAIGDPTKIVSVKQSKQTKNGNDDKLIPPAVLRELTLLSEIN-FPHIIHTSIKDVFYDSDNHVLAFVYDYGAFDVRKLIRFY
|. ..|.| ||||.|.|.    . . || .|. . . .  .|  .|   .||. .| |..  | |.  ...||..    . |  | .|  .| .|. . .
YQKIEKIGEGTYGVVYKCKDMQTNQ-IVALKKIRLEQEDEGD-GVPSTAIREISCLKELKDHPNIV--KLHDVIHQ---NKLYMVFEYLDMDLKKYMDMS

LSRKQIVSEMVTKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENSKIPGIVKLIDFGLARAIDNTNFPKNT-G--VVTVWYRAPELLLGDSHYDASI
.. .. ... . ||...|.| .... |||.|.| |. | |. |  . .     .|. |||||||. ...  . | .  ||| ||||||.|||...|. ..
IPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-----IKIADFGLARAF-GIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPV

DLWSAGCIFAEL---LLGDVLFKAETQNEQ
|.|| ||||||.        || .. . .|
DMWSIGCIFAEMFMDVTKKPLFHGDSEIDQ
Kinase 90729.m00113.AA MAPK 123-321 32 7.6e-50 170.5 In-house 118-328 (328) Show / Hide 
Range on Protein: 123-321
Range on HMM: 118-328/328
Sequence Identity: 32% (74 aa)

KSILFQLLLA--LDHIHQRGIIHCDITPPNLIIMPENSKIPGIVKLIDFGLARAIDNT-----NFPKN---------TGVVTVWYRAPELLLGD--SHYD
.....|.| .  | .||  ..||.|. | |. .   |.   . .|. |||||| ||..     .....           |.| ||||||..|.    ||.
QYFMYQILRGLKLKYIHSANVIHRDLKPSNILV---NEN--CDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYT

ASIDLWSAGCIFAELLL-GDVLFKAETQNEQNPTGFNK-NQLAKILEIMGPINESSIARPEWCAHLADYNRMT---KPKQKTSLQKLFQN----VNPKAF
 ..| ||.||||||.|  . .||.          | .  .|. .|.|..|   |  | . . . | ..| .     ....| ...|.| |    .||.| 
KAVDMWSVGCIFAEMLTDRKPLFP----------GKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAI

DLLIKMLEYNPYHRITAHDALRHEYF
||| |||. .| .|||. .||.|.||
DLLEKMLVFDPDKRITVEEALQHPYF
Kinase 90729.m00113.AA RCK 12-219 32 1.3e-46 145.79 In-house 1-207 (298) Show / Hide 
Range on Protein: 12-219
Range on HMM: 1-207/298
Sequence Identity: 32% (70 aa)

YTLLKKVGSGTYGEVFKASAIGDPTKIVSVKQSKQTKNGNDDKLIPPAVLRELTLLSEIN-FPHIIHTSIKDVFYDSDNHVLAFVYDYGAFDVRKLIRFY
|...|..| ||||.|.|| .. .  .||  |. | .|  . .  .    |||.. |  .|  |.||   .|.|..|.|.  |.||  |   .. .... .
YQIIKQLGDGTYGCVMKAQNK-ETGEIVAIKKMK-QKFYSWEECM---NLREIKSLRKLNPHPNIIK--LKEVIRDNDTYQLYFVFEYMDMNLYQMMKDF

LSRKQIVSEMV--TKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPE----NSKIPGIVKLIDFGLARAIDNTN-FPKNTGVVTV-WYRAPELLLGDSH
  |.. ..| .   |.|..|.|..|.|.|  |. | |. | |. ....    . . ....|..||||.| | . . .   |  |.. ||||||.|| . .
KERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPY---TDYVSTRWYRAPECLLRCTY

YDASIDLWSAGCIFAEL
|.  .|.|. |||..||
YNSPMDIWAVGCIMYEL
Kinase 90729.m00113.AA PITSLRE 102-321 36 2.4e-45 156.99 In-house 88-295 (295) Show / Hide 
Range on Protein: 102-321
Range on HMM: 88-295/295
Sequence Identity: 36% (82 aa)

DVRKLIRFYLSRKQIVSEMVTKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENSKIPGIVKLIDFGLARAIDNTNFPKNTGVVTVWYRAPELLLGDS
|.. |.    .|.|  ..  .|. . |||.. .| |   |.| |    || .  .     || |. ||||||       |   .||| ||||||||||  
DLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHK-----GILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCK

HYDASIDLWSAGCIFAELLLGDVLFKAETQNEQNPTGFNKNQLAKILEIMGPINESSIARPEWCAHLADYNRMT-KPKQKTS-LQKLFQ---NVNPKAFD
 |   .|.|| ||||||......||.   ..|        .|. .|   ||  .|..   | |   |   ..|.  |... . | |.|.    ..  .||
KYSTPVDMWSVGCIFAEFITMKPLFQG--KSEI-------DQINCIFKEMGTPTEKIW--PGW-TELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFD

LLIKMLEYNPYHRITAHDALRHEYF
|| .||.|||  |||| ||| |..|
LLNQMLTYNPKNRITASDALKHPWF
Kinase 90729.m00113.AA CDK7 12-221 32 5.2e-42 109.39 In-house 1-198 (288) Show / Hide 
Range on Protein: 12-221
Range on HMM: 1-198/288
Sequence Identity: 32% (71 aa)

YTLLKKVGSGTYGEVFKASAIGDPTKIVSVKQSK------QTKNGNDDKLIPPAVLRELTLLSEINFPHIIHTSIKDVFYDSDNHVLAFVYDYGAFDVRK
|. .|..| |... |.||       .|| .|  |      ..| |     |    .||  .| |.  . .|     |.|   .|  .  |.|.   |   
YEKIKHIGEGQFATVYKACDHQTG-QIVAIKKIKKLGHRSEAKDG-----INRTAIREIKILQEMQHDNVIG--LIDIFMHKSN--IQLVFDFMDWDLEV

LIRFYLSRKQIVSEMVTKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENSKIPGIVKLIDFGLARAID--NTNFPKNTGVVTVWYRAPELLLGDSHY
 |.     . |      |..  ..|. | . |.  | | |. | || . ..     |..|. ||||||..   | ..  .  ||| |||||||| |  ||
VIK---DKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNEN-----GQLKIADFGLARFYGSPNRIYTHQ--VVTRWYRAPELLFGARHY

DASIDLWSAGCIFAELLL
  ..|.|| |||||||.|
GTGVDMWSVGCIFAELML
Kinase 90729.m00113.AA CRK7 123-234 28 1.2e-27 92.26 In-house 115-261 (343) Show / Hide 
Range on Protein: 123-234
Range on HMM: 115-261/343
Sequence Identity: 28% (44 aa)

KSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENSKIPGIVKLIDFGLARAIDNTN-FPKNTG-VVTVWYRAPELLLGDSHY-----------------
|... |||. .| .|.....| ||   |. .   |.   |.||. ||||||     .  .. |  |.| |||.||||||. .|                 
KCFMKQLLEGMDYCHKKNFLHRDIKCSNILM--NNQ---GEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQ

---------------------DASIDLWSAGCIFAELLLGDVLFKAETQNEQ
                       .|| || |||..||. .  .|...   .|
LSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQ
Kinase 90729.m00113.AA CDC2 279-321 36 3.4e-17 48.91 In-house 250-301 (301) Show / Hide 
Range on Protein: 279-321
Range on HMM: 250-301/301
Sequence Identity: 36% (19 aa)

QKTSLQKLFQN---------VNPKAFDLLIKMLEYNPYHRITAHDALRHEYF
... |.|.. |         ..|...||| .|| |.|..||.| .||.| ||
KPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 90729.m00113.AA CDK7 243-321 28 1.8e-16 39.97 In-house 211-288 (288) Show / Hide 
Range on Protein: 243-321
Range on HMM: 211-288/288
Sequence Identity: 28% (23 aa)

QLAKILEIMGPINESSIARPEWCAHLADYNRMTK-PK-QKTSLQKLFQNVNPKAFDLLIKMLEYNPYHRITAHDALRHEYF
|| .| ...|  .|.    |. |. ..||. ... |   .| |...|      . ||. .|.  ||  |.|. ..| ..||
QLTRIFQTLGTPTEEEW--PNMCC-MMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 90729.m00113.AA RCK 277-321 37 1.6e-15 45.43 In-house 254-298 (298) Show / Hide 
Range on Protein: 277-321
Range on HMM: 254-298/298
Sequence Identity: 37% (17 aa)

PKQKTSLQKLFQNVNPKAFDLLIKMLEYNPYHRITAHDALRHEYF
......|..|. | .. . .|. ||| ..|  ||||. ||.| ||
QCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 90729.m00113.AA CRK7 276-321 33 9e-15 47.18 In-house 290-343 (343) Show / Hide 
Range on Protein: 276-321
Range on HMM: 290-343/343
Sequence Identity: 33% (18 aa)

KPKQ--KTSLQKLFQ------NVNPKAFDLLIKMLEYNPYHRITAHDALRHEYF
|||.  .. | . |       .  ....|||.||| ..|  |.|| ..|.|..|
KPKRQYNRRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 90729.m00113.AA TyrKc 12-321 17 9.4e-08 -97.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-321
Range on HMM: 1-280/280
Sequence Identity: 17% (60 aa)

YTLLKKVGSGTYGEVFKASAIGDPTKIVSVKQSKQTKNGNDDKLIPPAVLRELTLLSEI--NFPHIIHTSIKDVFYDS-----DNHVLAFVYDYGAF-DV
 ||.|| |.| .|||.|. ..      | ||  |  .          . .||. .....  . |.|.   .  |  ..       . |  |  | .  | 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVR--LYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

RKLIRFYLSRKQIVSEMVTKSILFQLLLALDHIHQRGIIHCDITPPNLIIMPENSKIPGIVKLIDFGLARAIDNT--------NFPK----NT-GVVTVW
.. .| .  .   ..     |. .|     ...|....|| |.   |  .  ..     .||  ||||.|.|..            |    .. ... . 
KDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR

YRAPELLLGDSHYDASIDLWSAGCIFAELL-LGDVLFKAETQNEQNPTGFNKNQLAKILEIMGPINE----SSIARPEWCAHLADYNRMTKPKQKTSLQK
  ||| .  .. .    | || |    |.. .|.     ..|.    . .   .. |  . | .  .    |                            
WMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------

LFQNVNPKAFDLLIKMLEYNPYHRITAHDALRHEYF
 |    .. ...  .  ...|  | |  .   ||.|
-FVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 90729.m00113.AA CRK7 12-29 50 4e-06 16.93 In-house 1-18 (343) Show / Hide 
Range on Protein: 12-29
Range on HMM: 1-18/343
Sequence Identity: 50% (9 aa)

YTLLKKVGSGTYGEVFKA
| ... .|.|||| | ||
YEMIMQIGEGTYGQVYKA
Kinase 90729.m00113.AA MAPK 12-29 50 1e-05 15.46 In-house 1-18 (328) Show / Hide 
Range on Protein: 12-29
Range on HMM: 1-18/328
Sequence Identity: 50% (9 aa)

YTLLKKVGSGTYGEVFKA
|..||..|.| || |..|
YQILKPIGQGAYGVVCSA
Kinase 90729.m00113.AA Pkinase_Tyr 12-76 25 7.3e-05 17.09 Pfam 1-67 (270) Show / Hide 
Range on Protein: 12-76
Range on HMM: 1-67/270
Sequence Identity: 25% (18 aa)

YTLLKKVGSGTYGEVFKASAI---GDPTKIVSVKQSKQTKNGNDDKL-IPPAVLRELTLLSEI-NFPHII
 |..|| |.| .|||.|. .    ....  | ||  |.   | ...  .  . .||. ..... . |.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIV
Kinase 90729.m00113.AA PITSLRE 12-29 38 0.001859 8.7 In-house 1-18 (295) Show / Hide 
Range on Protein: 12-29
Range on HMM: 1-18/295
Sequence Identity: 38% (7 aa)

YTLLKKVGSGTYGEVFKA
.  | ... ||||.|..|
FQCLNRIHEGTYGVVYRA