Gene GL50803_14004 (G.lamblia)

GL50803_14004

Species: G.lamblia
Alias: GK040, GL50803_14004
External Links: GiardiaDB ,
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MOK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_14004.AA Protein None 545 None Fasta, JSON
GL50803_14004.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of GL50803_14004.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_14004.AA RCK 19-304 45 1.6e-151 484.25 In-house 1-298 (298) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-298/298
Sequence Identity: 45% (136 aa)

YKFVSKKGAGAFSDVIKAQCVKTEEYVAIKRMKATFKSIEQITSLREIQSLRRLADQPFIIRLIEILFDRTTGRLALVFELMEMNLYELIKN---RKYHL
|......|.|....|.||| ..| |.||||.|| .|.|.|....||||.|||.|   | || |.|...|..|..|..|||.|.||||...|.   |. .|
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYL

PESS--IKWYMWQLLHAVRIAHASGTFHRDIKPENILLDD---------KDNLKLSDFGSCRGIHTQLPYTEYISTRWYRSPECLLTDGVYGPEMDLFGV
||.   || .| |.| .    |  | ||||.|||||.. .          |..|. |||.|| |  . |||.|.||||||.|||||... |   ||...|
PENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAV

GCVMFEITALFPLFPGKDELDQITRIHAILGTPPKELIQRIRKGA-KNNPIKGDFPPQKGSGLAKLIPHASSTAIDLMLKLMEYDPQKRITAEEALRHPF
||.|.|.. |.||||| .|.|||  |. ..||| |.      .|  . . .  .||. ||..| .|||..|. .|.|| |.. .||||||||..||.||.
GCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKK---DWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPY

F
|
F
Kinase GL50803_14004.AA MOK 19-304 50 8.4e-138 434.74 In-house 1-283 (283) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-283/283
Sequence Identity: 50% (145 aa)

YKFVSKKGAGAFSDVIKAQCVKTEEYVAIKRMKATFKSIEQITSLREIQSLRRLADQPFIIRLIEILFDRTTGRLALVFELMEMNLYELIKNRKYHLPES
|| . | | |.||.|.| | ..  .| | |.||  |.||||. .||||| .|||   | |. | |..||| || |||. |||.||.||||. |.. ||. 
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQK

SIKWYMWQLLHAVRIAHASGTFHRDIKPENILLDDKDNLKLSDFGSCRGIHTQLPYTEYISTRWYRSPECLLTDGVYGPEMDLFGVGCVMFEITALFPLF
 |. ||.||. ..   |  | ||||.||||||. . | |||.|||||| .  . |||||||||||| |||||||| |  .||.. |||| .|| .| |||
KIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQ-DHLKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPLF

PGKDELDQITRIHAILGTPPKELIQRIRKGAKNNPIKGDFPPQKGSGLAKLIPHASSTAIDLMLKLMEYDPQKRITAEEALRHPFF
||  |.|||..|| ..||| ...... .. ..   .  ||| .||||. ||.| ..  ....| |.. |||  ||||. ...||.|
PGVNEVDQISKIHDVMGTPCQKILNKFKNQSRA--MNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase GL50803_14004.AA CMGC 19-304 22 2.7e-110 363.82 In-house 1-513 (513) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-513/513
Sequence Identity: 22% (117 aa)

YKFVSKKGAGAFSDVIKAQC--------------VKTEEYVAIKRMKATFKSIEQI----------TSLREIQSLRRLA----------------DQPFI
|. ..| | |... | |...               .|.|.||||..|  |. ...           ..||||. |..|                 . . |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IRLIEILFDRTTG---------------RLALVFELMEMNLYELIKNRKY--------HLPESS------------IKWYM------WQLLHAVR--IAH
..|..|. .. .                 | ||||.|...||..||| .         .|.|              || .|      .|.| ..     |
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

ASG--TFHRDIKPENILLDDK--------------------DNLKLSDFGSCRGIHTQL----------------------PYTEYISTRWYRSPECLLT
  .   .|||.||||||....                    ..||. |||..| .|.                        |||.|..|||||.|| || 
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

D---------GVYGPEMDLFGVGCVMFEITA--------LFPLFPGKDE-----------LDQITRIHAILGTP----------------PKELIQRIR-
.         . |....|  .|||...|.          . |||||..|           .||. .|  .||||                ..| ...|  
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

-------------------KGAKNNPIKG--DFPPQKGSGLAKLIPH-----------------------------------ASSTAIDLMLKLMEYDPQ
                   .    |.|.   .||....  . .|.|                                    ... ||||. |...|||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRITAEEALRHPFF
||||||.||.||.|
KRITAEQALQHPYF
Kinase GL50803_14004.AA MAK 19-240 36 1.9e-84 268.68 In-house 1-270 (352) Show / Hide 
Range on Protein: 19-240
Range on HMM: 1-270/352
Sequence Identity: 36% (98 aa)

YKFVSKKGAGAFSDVIKAQC------------------------------VKTEEYVAIKRMKATFKSIEQITSLREIQSLRRLADQPFIIRLIEILFDR
| .. . |.|.. .|..|.                               ..| | |||||||  | | |  ..|||. ||. |   | |..| |.. | 
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

TTGRLALVFELMEMNLYELIKNRKY-HLPESSIKWYMWQLLHAVRIAHASGTFHRDIKPENILLDDK-----------------DNLKLSDFGSCRGIHT
    | .||| |. |||...| |.  |.||..|.  |.| | .    |  | ||||.|||||..                    . .|. |||  | |  
ENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLAREIRS

QLPYTEYISTRWYRSPECLLTDGVYGPEMDLFGVGCVMFEITALFPLFPGKDELDQITRIHAILGTPPKE
. ||| |.||||||.|| ||  ..|.  .|.  |||.| |.. . |||||  | |||  |  .|||| |.
KPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKD
Kinase GL50803_14004.AA S_TKc 19-304 29 3e-82 280.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-231/231
Sequence Identity: 29% (90 aa)

YKFVSKKGAGAFSDVIKAQCVKTEEYVAIKRMKATFKSIEQITSLREIQSLRRLADQPFIIRLIEILFDRTTGRLALVFELMEM---NLYELIKNRKYH-
|... | | |||. | |.. .|| ..||||..|        .. .|||| |..  . |.|..|...  |   ..| .|.|...    .|...||.|..| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPESSIKWYMWQLLHAVRIAHASGTFHRDIKPENILLDDKDNLKLSDFGSCRGIHTQLPYTEYISTRWYRSPECLLTDGVYGP-EMDLFGVGCVMF
    .||  .. ||.|.. |.   |  |  |||.||||||||.  ..|..|||..| .      | .. |.||..|| |     ||. . |   .||...
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY

EITALFPLFPGKDELDQITRIHAILGTPPKELIQRIRKGAKNNPIKGDFPPQKGSGLAKLIPHASSTAIDLMLKLMEYDPQKRITAEEALR-------HP
|  .  |.||      |. ..  ..|                                      |. |.|.. |....||.||.|| |||.       ||
EMLCGYPPFP------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

FF
.|
WF
Kinase GL50803_14004.AA CDK 19-304 30 1.5e-76 244.41 In-house 1-284 (284) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-284/284
Sequence Identity: 30% (97 aa)

YKFVSKKGAGAFSDVIKAQCVKTE-----EYVAIKRMKATF------KSIEQITSLREIQSLRRLADQPFIIRLIEILFDRTTG---------RLALVFE
|. . | | |..  | ||.. .|      ..||.|. .         |    ||..|||  |. |   | |..|...  . ..          .| .|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

LMEMNLYELIKNRKYHLPESSIKWYMWQLLHAVRIAHASGTFHRDIKPENILLDDKDN-----LKLSDFGSCRGIH-------TQLPYTEYISTRWYRSP
 |.. |.....          ||.|||||| ..   |  .  |||.|| |||.... .     ||. |||  |  .        . .||  . |.|||.|
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ECLLTDGVYG--PEMDLFGVGCVMFEITA---LFPLFPGKDELDQITRIHAILGTPPKELIQRIRKGAKNNPIKGDFPPQKGSGLAKLIPHASSTAIDLM
| || .  |.  .. |. .|||.. |.       |||||. |.||. .|  |.|||  .    . |                               ||.
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------DLL

LKLMEYDPQKRITAEEALRHPFF
 |.. |||.|||.||.|| ||.|
NKMLCYDPKKRISAEQALQHPYF
Kinase GL50803_14004.AA CDC2 19-304 34 5.3e-73 223.55 In-house 1-301 (301) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-301/301
Sequence Identity: 34% (105 aa)

YKFVSKKGAGAFSDVIKAQCVKTEEYVAIKRMKATFKSIEQ---ITSLREIQSLRRLADQPFIIRLIEILFDRTTGRLALVFELMEMNLYELIK---NRK
|. . | | | .  |.|.. ..| ..||.|. . .  . .     |..|||  |  | | | |..| ....     .| .||| ..|.| .. .     .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

YHLPESSIKWYMWQLLHAVRIAHASGTFHRDIKPENILLDDKDNLKLSDFGSCRGIHTQL-PYT--EYISTRWYRSPECLLTDGVYGPEMDLFGVGCVMF
.|.|.. .| ||.|.| .|   |. . .|||.|| |||.|.| |.|..|||  | . . . .||    . |.|||.|| || .  |  . |.  .||.. 
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EI---TALFPLFPGKDELDQITRIHAILGTPPKELIQRIRKGAKNNP-IKGDFPPQKGSGLAKLIPH---------ASSTAIDLMLKLMEYDPQKRITAE
|.       |||.|. | ||. .|  |||||  .  .    | ...|  | .||  | ..| |..|          .  ..|||  ..  |||||||.|.
EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWP----GVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAK

EALRHPFF
|||.||.|
EALQHPYF
Kinase GL50803_14004.AA Pkinase 19-304 28 1.9e-72 251.77 Pfam 1-293 (293) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-293/293
Sequence Identity: 28% (89 aa)

YKFVSKKGAGAFSDVIKAQCVKTEEYVAIKRMKATFKSIEQ-ITSLR--EIQSLRRLADQPFIIRLIEILFDRTTGRLALVFELMEM-----NLYELIK-
|....| |.|.|. | |.. ..|.. ||.|..|   .. .. .| .|  ||| ..|| . |.|.||...  |   ... .|.|..|.      |...|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

NRKYHL--PESSIKWYMWQLLHAVRIAHASGTFHRDIKPENILLDDKDNL----KLSDFGSCRG--IHTQLPYTEYISTRWYRSPECLLTDGVYGPEMDL
 |.  .  .|  .| ||.|.| ..   |. |  |||.||||||.|.....    |..|||...   .  .  .| .  |.||..|| ....  |||. | 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FGVGCVMFEITALFPLFPGK----DELDQITRIHAILGTPPKELIQ----------RIRKGAKNNPIKGDFPPQKGSGLAKLIPHASSTAIDLMLKLMEY
...||...|     |.|||.    . .||. .|  |.|.|... ..          |. . .                . .. . .|....|.. .. ..
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H--------------F-HWTF-HNWSEECKDFIKWCLCK

DPQKRITAEEALRHPFF
||.||.|||..| ||.|
DPKKRPTAEQILQHPWF
Kinase GL50803_14004.AA MAPK 19-304 32 3.1e-67 229.66 In-house 1-328 (328) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-328/328
Sequence Identity: 32% (107 aa)

YKFVSKKGAGAFSDVIKAQCVK------TEEYVAIKRMK-ATFKSIEQITSLREIQSLRRLADQPFIIRLIEILFDR-----TT----GRLALVFELMEM
|. ... | ||.  | .| ...      ....||||..  .  . . .   .|||  ||.. . . ||.|..|.         .      . .|.|||| 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NLYELIKNRKYHLPESSIKWYMWQLLHA--VRIAHASGTFHRDIKPENILLDDKDNLKLSDFGSCRGIHTQLPY---------------TEYISTRWYRS
.|. .|| .. .| .  |.  |.|.| .  .   |  .  |||.||.|||..  . ||. |||  |.|...  .               |||..|||||.
DLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRA

PECLLTD--GVYGPEMDLFGVGCVMFEITA-LFPLFPGKDELDQITRIHAILGTPPKELIQRIR-KGAKNNPIKGD--FPPQKGSGLAKLIP----HASS
|| .|      |   .|   ||| . |      ||||||| .||...| ..||||..|.||.|    .  | |..   .|....  ..|..|    .|..
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANP

TAIDLMLKLMEYDPQKRITAEEALRHPFF
 ||||. |. . ||.||||.||||.||.|
QAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase GL50803_14004.AA ERK7 19-304 34 1.6e-61 209.07 In-house 1-292 (292) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-292/292
Sequence Identity: 34% (102 aa)

YKFVSKKGAGAFSDVIKAQCVKTEEYVAIKRMKATFK-SIEQITSLREIQSLRRLADQPFIIRLIEILFDRTTGRLALVFELMEMNLYELIKNRKYHLPE
|.  .. | ||.  | || . .| . ||.|..   |. ..      |||  |. . . | |||||...       . |||| ||  |   |. .   | .
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIR-KGNILKD

SSIKWYMWQLLHAVRIAHASGTFHRDIKPENILLDDKDNLKLSDFGSCRGIHTQL-------PYTEYISTRWYRSPECLLTDGVYGPEMDLFGVGCVMFE
   .  |.||| |..  |     |||.|| ||||| .  .|. |||  | |  |          |||. |||||.|| ||    | .  |. ..||.. |
IHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGE

ITALFPLFPGKDELDQITRIHAILGTPPKELIQRIRKGAKNNPIKGDFPPQKGSGLAKLIPHASSTAIDLMLKLMEYDPQKRITAEEALRHPFF
.    |.|||   ..|| .|  ... | .| |. |      | ..   . ||   | ...|...  ||||. .|. . |.||.|||.||.||. 
MLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLE-QMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase GL50803_14004.AA CDKL 19-304 35 5.4e-61 207.27 In-house 1-286 (286) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-286/286
Sequence Identity: 35% (104 aa)

YKFVSKKGAGAFSDVIKAQCVKTEEYVAIKRMKA-TFKSIEQITSLREIQSLRRLADQPFIIRLIEILFDRTTGRLALVFELMEMNLYELIKNRKYHLPE
|   .| | |.   | |     | ..||||. |      ..  . .|||  |. |  .. |  |||.   |  ..| |||| .. .. .. . .   ..|
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLK-HENIVNLIEVF--RRKRKLHLVFEYCDHTVLHELEEYPNGVDE

SSIKWYMWQLLHAVRIAHASGTFHRDIKPENILLD-DKDNLKLSDFGSCRGIHTQLP--YTEYISTRWYRSPECLLTDGVYGPEMDLFGVGCVMFEITAL
. .. ||||.| |.   |     ||||||||||.   .. .|| |||  | . ..    ||.|  |||||.|| |. |  ||.. |.  .|||| | .  
HVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDG

FPLFPGKDELDQITRIHAILGTPPKELIQRIRKGAKNNPI-KG-DFP-PQKGSGLAKLIPHAS-STAIDLMLKLMEYDPQKRITAEEALRHPFF
 ||.||. ..||  .|   ||    .||.|  .  . ||. .|  || ...   | |  | .| ..|.|.| |... || .|.|.|....||.|
QPLWPGQSDIDQLYHIQKCLG----PLIPRHQEIFSKNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase GL50803_14004.AA p38 95-304 37 3.7e-55 186.87 In-house 85-289 (289) Show / Hide 
Range on Protein: 95-304
Range on HMM: 85-289/289
Sequence Identity: 37% (78 aa)

LVFELMEMNLYELIKNRKYHLPESSIKWYMWQLLHAVRIAHASGTFHRDIKPENILLDDKDNLKLSDFGSCRGIHTQLPYTEYISTRWYRSPECLLTDGV
.| ..|.  |. ..|  .  | .  |.    |.| . .  |. |  ||| || || . .   |.  |||  |  |.    |.|. |||||.|| .|  . 
MVTHFMGADLNNIMKCQR--LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR--HCDDEMTGYVATRWYRAPEIMLNWMH

YGPEMDLFGVGCVMFEITALFPLFPGKDELDQITRIHAILGTPPKELIQRIRKGAKNNPIKGDFPPQKGSGLAKLIPHASSTAIDLMLKLMEYDPQKRIT
|    |   |||.| |.    .||||.| .||..|| ...|||..|..|.| . .  | |..  |. .   .... . |.  ||||. |. | || ||||
YTQTVDIWSVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQS-YPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRIT

AEEALRHPFF
||||..||.|
AEEAMQHPYF
Kinase GL50803_14004.AA MAK 258-304 37 1e-16 49.35 In-house 302-352 (352) Show / Hide 
Range on Protein: 258-304
Range on HMM: 302-352/352
Sequence Identity: 37% (19 aa)

FPPQKG---SGLAKLIPHASS-TAIDLMLKLMEYDPQKRITAEEALRHPFF
||   .   . | .||| .|.  ||.|| .....||.|| ||......|.|
FPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase GL50803_14004.AA TyrKc 19-304 20 6.8e-12 -30.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-304
Range on HMM: 1-280/280
Sequence Identity: 20% (65 aa)

YKFVSKKGAGAFSDVIKAQCVKTEEYVAIKRMKATFKSIEQITSLREIQSLRRL-ADQPFIIRLIEILFDR-----TTGRLALVFELMEM-NLYELIKNR
 ..  | | |||  | |..     . ||.| .|.    .| .  .||.. ...|  . | |.||. .  .        . | .|.|.|.  .| . ....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDF--MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KYHLPESSIKWYMWQLLHAVRIAHASGTFHRDIKPENILLDDKDNLKLSDFGSCRGIHTQ-------LPYT------EY--ISTRWYRSPECLLTDGVYG
. .|. .    ..||     .  |  .  |||.   |.|....   | |||| .| |.           |.      .   .  ||. .|||.  .|.. 
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKFT

PEMDLFGVGCVMFEITALFPLFPGKDELDQITRIHAILGTPPKELIQRIRKGAKNNPIKG----DFPPQKGSGLAKLIPHASSTAIDLMLKLMEYDPQKR
.. | .  | .|.||  .     ..   ..| .       ...|.|.....|    . .      |            .....   ..|..  ..|| .|
TKSDVWSFGVCMWEIFTY----GQQPYPGMIQQ-----MMSNQEVIEYVKQGYRMPQPPNDYPMSF------------VCCPDEMYQIMKQCWHEDPEDR

ITAEEALRHPFF
 | .|   | .|
PTFSEI--HECF
Kinase GL50803_14004.AA p38 19-58 32 5.6e-08 23.05 In-house 1-43 (289) Show / Hide 
Range on Protein: 19-58
Range on HMM: 1-43/289
Sequence Identity: 32% (14 aa)

YKFVSKKGAGAFSDVIKAQCVKTEEY---VAIKRMKATFKSIE
|....  | ||.  |.|| ...|...   ||||..   | |..
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEI
Kinase GL50803_14004.AA Pkinase_Tyr 19-126 24 0.000409 14.56 Pfam 1-119 (270) Show / Hide 
Range on Protein: 19-126
Range on HMM: 1-119/270
Sequence Identity: 24% (29 aa)

YKFVSKKGAGAFSDVIKAQCV----KTEEYVAIKRMKATFKSIE--QITSLREIQSLRRLADQPFIIRLIEILFDRTTG-RLALVFELMEM-NLYELIKN
 .|  | |.||| .| |. .     .|.  ||.| .| .  . .  .   .||.. .. | . | |.||. .  |.    .. .|.|.|.  .|..  ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---KYHLPESSIKWYMWQ
.   | .|. . .  . ||
HREDKQPLTMKDLLQMCWQ
Kinase GL50803_14004.AA Pkinase_Tyr 148-163 37 1.559648 2.43 Pfam 141-156 (270) Show / Hide 
Range on Protein: 148-163
Range on HMM: 141-156/270
Sequence Identity: 37% (6 aa)

NILLDDKDNLKLSDFG
|.|....   | .|||
NCLVTENNVVKICDFG