Gene GL50803_16279 (G.lamblia)

GL50803_16279

Species: G.lamblia
Alias: GK256, GL50803_16279
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_16279.AA Protein None 661 None Fasta, JSON
GL50803_16279.kin_dom Protein Kinase Domain None 316 None Fasta, JSON

Protein domain

Protein domains of GL50803_16279.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_16279.AA S_TKc 9-324 24 5e-44 153.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-324
Range on HMM: 1-231/231
Sequence Identity: 24% (79 aa)

YDVAAMIGMGTQAKIHHCMDRATGEELVVKIIYYGDIDRDSKEYYGMSREGYLMQGFHHPYILPVREVVIDSRLQTINIIMPLMKY---SLKKLIQSHRR
|..   || |. .| . | .. ||..  .|||              . ||  ...  |||.|    .|  |   . . ..| ..     .|...|....|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

RR--EPIPEADIWKYTYQLLSALHYLHDPSTEAWYKIPELLSRSTSRRPSCIDDKSGNTEDDQGTVDSARIHFPIPHRDIKPDNILLDYDNNIKLADFTM
..   |.|| ....|.||...|| |.|.                                           |  | |||.||.|||||   .||..|| .
HGLRFPFPE-HARFYMYQICCALEYCHS-------------------------------------------H-GIIHRDLKPENILLDE--HIKICDFGL

AAQFDEEELRQLKNITLDYVTNTEESGFAGAPGYRAPEAYYSVAGV-ENDIWALGCVVYEMATTERLFPNTDVQKAYFSGENRFGICLPGRSSELVKLVE
|.|.                     . | | | |.|||      |  . |.|..||..|||.. . .||  ..|. .              |.|.  ...
ARQL---------------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIR

AMLTINPAARPRASQLLR-------NPCF
 .|. .|. || | ..|.        | |
KCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase GL50803_16279.AA Pkinase 9-324 21 4e-41 146.48 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-324
Range on HMM: 1-293/293
Sequence Identity: 21% (78 aa)

YDVAAMIGMGTQAKIHHCMDRATGEELVVKIIYYGDIDRDSKEY---YGMSREGYLMQGFHHPYILPVREVVIDSRLQTINIIMPLMKYSLKKLIQSH--
| .   || |. ..  .|... ||.. .|||| . ... . ...       .| ..|. ..||.|.  .... |   . | ..|...   |. ..  .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFDY

--RRRREPI--PEADIWKYTYQLLSALHYLHDPSTEAWYKIPELLSRSTSRRPSCIDDKSGNTEDDQGTVDSARIHFPIPHRDIKPDNILLDYDNNI---
  ..|. ..  .| .. .| ||.|..| |.|.                                              | |||.||.|||.| ...|   
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--------------------------------------------GIIHRDLKPENILIDNNGHIDAC

-KLADFTMAAQFDEEELRQLKNITLDYVTNTEESGFAGAPGYRAPEA--YYSVAGVENDIWALGCVVYEMATTERLFPNT------DVQKAYFSGEN---
 |..||  |.|||             |  |.  ..|.| |.|.|||    ..  | . |.|..||..|||.. . .||.       | .. ..       
VKICDFGLAKQFD-------------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPL

---RFGICLPGRS---------------SELVKLVEAMLTINPAARPRASQLLRNPCF
   ..  | . ..               .|. .... .|. .|. || | |.|  | |
HFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_16279.AA Ciliate-E2 180-324 22 5.7e-24 79.16 In-house 184-365 (365) Show / Hide 
Range on Protein: 180-324
Range on HMM: 184-365/365
Sequence Identity: 22% (45 aa)

HRDIKPDNILLDYDNNIKLADFTMAAQFDEE--------------ELRQLKNITLDYVTNTEESGF----------AGAPGYRAPEAYYSVA--------
||||||.|||.     ||..|| .. ..|..              . .. ...|  |        .          .| ||| ||| . .          
HRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQK

--GVENDIWALGCVVYEMATTERLFPNTDVQKAYFSGENRFGICL---------------PGRSSELVKLVEA----MLTINPAARPR-ASQLLRNPCF
  . . |||.||.. ||| . .. |     |.    .. .|                      | |   |       ||  .|  |.  ..|.| .| |
GYDYKCDIWSLGVILYEMLFGKPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_16279.AA Ciliate-E2-Unclassified 180-324 23 1.3e-21 71.72 In-house 167-352 (352) Show / Hide 
Range on Protein: 180-324
Range on HMM: 167-352/352
Sequence Identity: 23% (44 aa)

HRDIKPDNILLDYDN---NIKLADFTMAAQFDEEELRQLKN--ITLDYVTNTEESGFAGAPGYR----APEAYYS-VAG----VENDIWALGCVVYEMAT
||||||.|||.| ..   .||..||  . . .. .  . .|    ...  . . . |.| |.|     ||| . .   .     . |||.||.. ||| .
HRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLF

TERLFPNTDVQK---------------AYFSGENRFGICLPG--------RSSELVK-LVE----AMLTINPAARPRASQLLRNPCF
 .. |. ..  .                ...  .   |. |         ..|. .| ...     ||  ||  |. ..|.|  | |
GYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_16279.AA STE 178-324 26 2.8e-19 64.83 In-house 173-359 (359) Show / Hide 
Range on Protein: 178-324
Range on HMM: 173-359/359
Sequence Identity: 26% (52 aa)

IPHRDIKPDNILLDYDNNIKLADFTMAAQFDEE--ELRQLKNI------TLDYVTNTEESGFAGAPGYRAPEAYY-------SVAGVENDIWALGCVVYE
| ||||||.||||     .||.||  ..|....  .. | .|.      | .  .||    |.| | . |||          .  ..  ||| |||.. |
IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNT----FVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIE

MATTERLFPN-TDVQKAYFSGEN--------------RFGICLPGR--------------------SSELVKLVEAMLTINPAARPRASQLLR--NPCF
||| .  . . .. .  .    |                   || .                    |.|.   ..  |...|  || |||||.   | .
MATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_16279.AA CAMKL 180-324 26 6.6e-19 56.84 In-house 150-297 (297) Show / Hide 
Range on Protein: 180-324
Range on HMM: 150-297/297
Sequence Identity: 26% (44 aa)

HRDIKPDNILLDYDN--NIKLADFTMAAQFD-EEELRQLKNITLDYVTNTEE--SGFAGAPGYRAPEAYYS--V--AGVENDIWALGCVVYEMATTERLF
||||||.|||||...  |||..|| ......               . ....  . | | | | ||| . .      | . |||..| . | | . .  |
HRDIKPENILLDENGNNNIKIIDFGFSNMYRPC-------------IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF

PNTDV------QKAYFSGENRFGICLPG----RSSELVKLVEAMLTINPAARPRASQLLRNPCF
 . ..       . |.  ... | . |      | ..  |   ||. ||  || . |... | .
DDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase GL50803_16279.AA STE11 180-324 30 1.2e-18 64.27 In-house 139-303 (303) Show / Hide 
Range on Protein: 180-324
Range on HMM: 139-303/303
Sequence Identity: 30% (51 aa)

HRDIKPDNILLDYDNN-IKLADFTMAAQFDEEELR-QLKNITLDYVTNTEESGFAGAPG--------YRAPEAYY-SV---AGVENDIWALGCVVYEMAT
|||||..||||| |.| .|||||  | .. .. .. . .| | .   ..    . | |         . ||| .  .     |   |||.|||.|.||||
HRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQN-HCKS----MTGTPYNSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMAT

TERLFPNTD---VQKAYFSGEN-RFGICLPGRSS-------ELVKLVEAMLTINPAARPRASQLLRNPCF
. . ..| |    .  .  |..    . .| . |       |.   .   ....|  || |.|||. | .
GKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase GL50803_16279.AA CMGC 9-130 16 4.2e-17 51.86 In-house 1-199 (513) Show / Hide 
Range on Protein: 9-130
Range on HMM: 1-199/513
Sequence Identity: 16% (32 aa)

YDVAAMIGMGTQAKIHHCMD--------------RATGEELVVKIIYYGDIDRDSK---EYYGMS----REGYLMQGF-----------------HHPYI
|..   || || ..   | |              . |.|.  .|.|     ... |   |  |..    ||  ... .                 ||..|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

LPVREVVIDSR---------------LQTINIIMPLMKYSLKKLIQSHRR-----RREPIPEAD------------IWKYT------YQLLSALH--YLH
.  .... ..                .. ..... .| ..|...|.....     |. | .|              | ...      ||.| .|.  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH
Kinase GL50803_16279.AA NEK 96-201 23 9.2e-17 55.89 In-house 94-167 (286) Show / Hide 
Range on Protein: 96-201
Range on HMM: 94-167/286
Sequence Identity: 23% (26 aa)

LKKL---IQSHRRRREPIPEADIWKYTYQLLSALHYLHDPSTEAWYKIPELLSRSTSRRPSCIDDKSGNTEDDQGTVDSARIHFPIPHRDIKPDNILLDY
| ..   |. .. ......|  ||.. .|...||.|.|| .                                            | |||||| || |. 
LYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRK-GP--------------------------------------QRKILHRDIKPQNIFLTK

DNN----IKLADF
.||    .|. ||
NNNDYHNVKIGDF
Kinase GL50803_16279.AA CAMK 180-263 26 2.3e-14 42.02 In-house 202-327 (425) Show / Hide 
Range on Protein: 180-263
Range on HMM: 202-327/425
Sequence Identity: 26% (34 aa)

HRDIKPDNILLDYD-----------------NNIKLADFTMAAQFDEEELRQ----LKNITLDYVT-------NTEESGFAGAPGYRA-PEAYYSV----
|||.||.|||||..                 ||||..|| .|..||. |        |. .    .       .   . | | |.| | ||   .     
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------AGVENDIWALGCVVYEM
            | . |.|..|.. | |
MQNATDEEKPYYGPKCDMWSCGVILYIM
Kinase GL50803_16279.AA CAMK 14-131 15 1.4e-12 36.16 In-house 1-197 (425) Show / Hide 
Range on Protein: 14-131
Range on HMM: 1-197/425
Sequence Identity: 15% (30 aa)

MIGMGTQAKIHHCMDRATG------------EELVVKIIYYGDIDRD------------------------SKEYYGMSREGYLMQG-------FHHPYI
 .| |. .| . |... |.            ..  .|||    .. .                         |    . ||  .|.         .|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LPVREVVIDSR-----------------LQTINIIM---PLMKY-----SLKKLIQSHRRRR-----------EPIPEADIWKYTYQLLSALHYLHD
.   ||  |..                  . . ..|    ..        |   |..|....             ..|..  .|  |..||.||.|.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS
Kinase GL50803_16279.AA CDK 57-131 23 4.5e-12 34.77 In-house 57-126 (284) Show / Hide 
Range on Protein: 57-131
Range on HMM: 57-126/284
Sequence Identity: 23% (20 aa)

REGYLMQGFHHPYILPVREVVIDSRLQ---------TINIIMPLMKYSLKKLIQSHRRRREPIPEADIWKYTYQLLSALHYLHD
||  |..   ||.|  ...|.... .          .. .... | . |||..              |  |..|||..|||.|.
REISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD-------------IKCYMWQLLRGLHYCHS
Kinase GL50803_16279.AA TyrKc 9-328 15 4.2e-11 -43.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-328
Range on HMM: 1-280/280
Sequence Identity: 15% (53 aa)

YDVAAMIGMGTQAKIHHCMDRATGEELVVKIIYYGDIDRDSKEYYGMSREGYLMQGF--HHPYILPVREVVIDS-----RLQTINIIMPLMKY-SLKKLI
     ..| |   ...... .   ..  || .  .           . ||  .|  .  ||| |.    |....       . . |.| .|.. .||. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

QSHRRRREPIPEADIWKYTYQLLSALHYLHDPSTEAWYKIPELLSRSTSRRPSCIDDKSGNTEDDQGTVDSARIHFPIPHRDIKPDNILLDYDNNIKLAD
..||..   .. .|  .. .|  .   |||.                                             .. |||.   |.|.. .. .| .|
RKHRPK---LCMKDLLSFCWQIACGMEYLHSK--------------------------------------------NCIHRDLAARNCLVGENHTVKISD

FTMAAQFDEEELRQLKNI------TLDYVTNTEESGFAGAPGYR--APEAY-YSVAGVENDIWALGCVVYEMATTERLFPN------TDVQKAYFSGENR
| ..        | ...       .  |.. ....| .  | .|  |||.  |..   . |.|. | . .|. |     .        . | ..   ...
FGLS--------RDIYDDDQQGESKDYYRKKEHKGGKTMLP-IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG

FGICLPGR---------SSELVKLVEAMLTINPAARPRASQLLRNPCFKDIL
.    |           ..|. .. .     .|. ||. |..      ....
YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase GL50803_16279.AA STE 9-131 17 6.9e-10 31.22 In-house 1-170 (359) Show / Hide 
Range on Protein: 9-131
Range on HMM: 1-170/359
Sequence Identity: 17% (30 aa)

YDVAAMIGMGTQAKIHHCMDR------ATGEE---------LVVKIIYYGDID-------------RDSKEYYGMSREGYLMQGFH--HPYILPVREVVI
..   .|| |.  . . .|..       |||.           .|.. . . .             ....|     .|  .|. ..  ||.|       .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----DSRLQTINIIMPLMK-YSLKKLIQSHRRRREP----------IPEADIWKYTYQLLSA-LHYLHD
     ..  ....|.| .|   || ..|..   . .|          .||  | ....|.| . |.|||.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHS
Kinase GL50803_16279.AA RCK 65-130 26 4.4e-09 24.67 In-house 54-122 (298) Show / Hide 
Range on Protein: 65-130
Range on HMM: 54-122/298
Sequence Identity: 26% (18 aa)

FH-HPYILPVREVVIDSRLQTINIIMPLMKYSLKKLIQSHRRRREPIPEAD--IWKYTYQLLSALHYLH
.. || |. ..||..|.   .  .....|.  | .....   || ..||    | .. ||.| .|...|
LNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYLPENQRSIKNIMYQILQGLAHMH
Kinase GL50803_16279.AA CAMKL 9-131 24 1.6e-08 23.13 In-house 1-145 (297) Show / Hide 
Range on Protein: 9-131
Range on HMM: 1-145/297
Sequence Identity: 24% (36 aa)

YDVAAMIGMGTQAKIHHCMD-RATGEELVVKIIYYGDIDRD------------SKEYYGMSREGYLMQGFH---HPYILPVREVVIDSRL----QTINII
|..   .| |. .|   ... | |||.  .|||    |  |            ..      ||  .|. ..   || |    ||. ...     . |...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MPLMKYS---LKKLIQSHRRRREPIPEADIWKYTYQLLSALHYLHD
| .       |   |..|..||...|| .  .|  |..||..|.|.
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHS
Kinase GL50803_16279.AA NEK 294-324 35 2.1e-08 26.13 In-house 256-286 (286) Show / Hide 
Range on Protein: 294-324
Range on HMM: 256-286/286
Sequence Identity: 35% (11 aa)

SSELVKLVEAMLTINPAARPRASQLLRNPCF
|..| .|.. ||. .|  || ..|.| .|. 
SQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_16279.AA CMGC 180-210 23 2.5e-08 22.5 In-house 207-257 (513) Show / Hide 
Range on Protein: 180-210
Range on HMM: 207-257/513
Sequence Identity: 23% (12 aa)

HRDIKPDNILLDYDNN--------------------IKLADFTMAAQFDEE
|||.|| |||.. ..                     .|..|| .| .....
HRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPH
Kinase GL50803_16279.AA CDK 180-201 44 4.5e-08 21.75 In-house 131-157 (284) Show / Hide 
Range on Protein: 180-201
Range on HMM: 131-157/284
Sequence Identity: 44% (12 aa)

HRDIKPDNILLDYDNN-----IKLADF
|||.|| |||.. . .     .|.|||
HRDLKPQNILINNNGEVKCGRLKIADF
Kinase GL50803_16279.AA RCK 294-324 38 5.7e-08 21.07 In-house 268-298 (298) Show / Hide 
Range on Protein: 294-324
Range on HMM: 268-298/298
Sequence Identity: 38% (12 aa)

SSELVKLVEAMLTINPAARPRASQLLRNPCF
|.....|.| ||...|  |. |.|.|. | |
SQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase GL50803_16279.AA RCK 180-201 38 1e-06 16.82 In-house 128-158 (298) Show / Hide 
Range on Protein: 180-201
Range on HMM: 128-158/298
Sequence Identity: 38% (12 aa)

HRDIKPDNILLDY---------DNNIKLADF
|||.|| ||..           ...||.|||
HRDLKPENIMCTGSQQYFEDQDQDHIKIADF
Kinase GL50803_16279.AA NEK 252-265 78 2e-06 19.36 In-house 206-219 (286) Show / Hide 
Range on Protein: 252-265
Range on HMM: 206-219/286
Sequence Identity: 78% (11 aa)

DIWALGCVVYEMAT
|||.||||.|||.|
DIWSLGCVLYEMCT
Kinase GL50803_16279.AA CMGC 294-324 32 3e-06 15.79 In-house 483-513 (513) Show / Hide 
Range on Protein: 294-324
Range on HMM: 483-513/513
Sequence Identity: 32% (10 aa)

SSELVKLVEAMLTINPAARPRASQLLRNPCF
..... |.. ||...|. |. |.| |. | |
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase GL50803_16279.AA CMGC 252-271 35 6e-06 14.61 In-house 317-344 (513) Show / Hide 
Range on Protein: 252-271
Range on HMM: 317-344/513
Sequence Identity: 35% (10 aa)

DIWALGCVVYEMATT--------ERLFP
|.|..||. .|| |         . |||
DMWSVGCIFAEMYTGYQSLIFRGKPLFP
Kinase GL50803_16279.AA CAMK 294-324 32 4.3e-05 11.57 In-house 395-425 (425) Show / Hide 
Range on Protein: 294-324
Range on HMM: 395-425/425
Sequence Identity: 32% (10 aa)

SSELVKLVEAMLTINPAARPRASQLLRNPCF
| |   |.  ||. .|  |. ..| |. | .
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_16279.AA CDK 300-324 40 7e-05 11.37 In-house 260-284 (284) Show / Hide 
Range on Protein: 300-324
Range on HMM: 260-284/284
Sequence Identity: 40% (10 aa)

LVEAMLTINPAARPRASQLLRNPCF
| . ||. .|. |  |.| |  | |
LLNKMLCYDPKKRISAEQALQHPYF
Kinase GL50803_16279.AA Ciliate-E2 9-130 16 8.1e-05 12.45 In-house 1-177 (365) Show / Hide 
Range on Protein: 9-130
Range on HMM: 1-177/365
Sequence Identity: 16% (29 aa)

YDVAAMIGMGTQAKIHHCMDRATGE-----------------------ELVVKIIYYGDIDRDSKEYYGMS---------REGYLMQGFHHPYILPVREV
|..  .|| |.....  | .. ...                       .  .||.   .|   ..| . |           |  ...   ||.|.   |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VIDSRLQTINIIMPLMKY-SLKKLIQSHRRRR-------EPIPEADIWKYTYQLLS---------------ALHYLH
 ..   ..| ..| . .. .|...|....  |       ... |  | ....|.|.               ||.|||
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLH
Kinase GL50803_16279.AA CDK 252-271 43 9.8e-05 10.89 In-house 204-226 (284) Show / Hide 
Range on Protein: 252-271
Range on HMM: 204-226/284
Sequence Identity: 43% (10 aa)

DIWALGCVVYEMAT---TERLFP
|.|..||. .||.|    . |||
DMWSVGCIFAEMFTDVTRKPLFP
Kinase GL50803_16279.AA RCK 252-271 55 0.000105 10.53 In-house 196-215 (298) Show / Hide 
Range on Protein: 252-271
Range on HMM: 196-215/298
Sequence Identity: 55% (11 aa)

DIWALGCVVYEMATTERLFP
||||.||. ||  .   |||
DIWAVGCIMYELYMLRPLFP
Kinase GL50803_16279.AA Ciliate-E2-Unclassified 9-130 17 0.002884 7.21 In-house 1-160 (352) Show / Hide 
Range on Protein: 9-130
Range on HMM: 1-160/352
Sequence Identity: 17% (28 aa)

YDVAAMIGMGTQAKIHHCMDRATGEELVVKIIYYGDIDRDSKEY-YG---------MSREG--------YLMQG--FHHPYILPVREVVIDSRLQTINII
| .   || | ..|...| .. .. .. .. .    .....| . .          | .           .||    .|| .. |... ..   |.| |.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MPLMKY-SLKKLIQS-------------HRRRREPIPEADIW-----KYTYQLLSALHYLH
| .... .|.. |..             ....|. ..|  .      .|..|.|..| |||
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLH
Kinase GL50803_16279.AA STE11 9-53 27 0.007776 6.43 In-house 1-48 (303) Show / Hide 
Range on Protein: 9-53
Range on HMM: 1-48/303
Sequence Identity: 27% (13 aa)

YDVAAMIGMGTQAKIHHCMDRATGEELVVKIIYYGDID---RDSKEYY
.   ..|| |.  . . ||.  |||...|| | .....    | ...|
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEY
Kinase GL50803_16279.AA STE11 117-131 60 0.05867 3.22 In-house 120-134 (303) Show / Hide 
Range on Protein: 117-131
Range on HMM: 120-134/303
Sequence Identity: 60% (9 aa)

KYTYQLLSALHYLHD
||| |.|..|.|||.
KYTKQILEGLQYLHS