Gene GL50803_3546 (G.lamblia)

GL50803_3546

Species: G.lamblia
Alias: GL50803_3546, GK178
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-GL1

Sequence

Name Sequence Type Origin Length Description Download
GL50803_3546.AA Protein None 517 None Fasta, JSON
GL50803_3546.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of GL50803_3546.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase GL50803_3546.AA Pkinase 19-280 25 8.8e-49 173.18 Pfam 1-293 (293) Show / Hide 
Range on Protein: 19-280
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

RDIGRPVGEGSYGTVYSLKSSPHK---VVKETPIRGLRPSALTALEI--EARVLPRMEHPNIVKYEAIEKTDQFFFVVMKYYPK-----SLDQLIKTAIR
  |||..|.||.|.||  .        .||. . |. ... . ..    |.... |. |||||..  .  ...   .|| | ..     .|  .|.|  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

SDKSL--SPEKIFIIVNQLASGLAYLHSPDKTDSTGKPLPAIIHRDLKPTNILVNSTETE---VAIADFGLCI---EGVANISMSSVATPCYSSPEALI-
.....  |.. .  .. |...||.|.||             |||||||| |||.... .    | |.||||.    .      .. . || | .|| .  
RHGCFYFSEWECKFYMYQILRGLEYCHSM-----------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

SKMYATSADMWSLGVIIYELTTGKRPDFLAG-----RNPEDVFTKDWKAPLGDIYD-----------------------PDLRLIIGHLLVLDPLERLTA
...| ...||||.|.|.||. .|. | |        ...  .. .. ..||   ..                       .... .|  .| .|| .|.||
GQYYGPKVDMWSCGCILYEMLCGR-PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

EELFQMTCF
|...|   |
EQILQHPWF
S_TKc GL50803_3546.AA S_TKc 19-280 26 3.5e-45 157.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-280
Range on HMM: 1-231/231
Sequence Identity: 26% (73 aa)

RDIGRPVGEGSYGTVYSLKSSP---HKVVKETPIRGLRPSALTALEIEARVLPRMEHPNIVKYEAIEKTDQFFFVVMKYYPK---SLDQLIKTAIR--SD
 .|.|..|.|..|.||  .      .  .|. .           .. | ..| .  ||||||.  .  . .....|| | .    .| ..||   |   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

KSLSPEKIFIIVNQLASGLAYLHSPDKTDSTGKPLPAIIHRDLKPTNILVNSTETEVAIADFGLCIEGVANISMSSVATPCYSSPEALISKMYAT-SADM
. ...  .  .. |....|.|.||             |||||||| |||...   .. |.||||. .      .. . || | .|| |    | . ..|.
FPFPE-HARFYMYQICCALEYCHSHG-----------IIHRDLKPENILLDE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDW

WSLGVIIYELTTGKRPDFLAGRNPEDVFTKDWKAPLGDIYDPDLRLIIGHLLVLDPLERLTAEELFQ-------MTCF
||.|.|.||. .|. |      ... .| |          .|... .| ..|. || .|.|| |..|       .  |
WSCGCILYEMLCGYPPFP----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_3546.AA TKL 60-278 20 7.7e-34 118.74 In-house 72-364 (364) Show / Hide 
Range on Protein: 60-278
Range on HMM: 72-364/364
Sequence Identity: 20% (63 aa)

LEIEARVLPRMEHPNIVKYEAIEKTDQF-------------FFVVMKYYPK-S-LDQLIKTAIRSDKSLSPEKIFIIVNQLASGLAYLHS--P-DKTDST
.| |.... |  |||||.. .. .  ..             .. || |.|. | |..|.           ..... .. . |.|..||||  |   |   
EEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCT---

GKPLPAIIHRDLKPTNILVNSTETE-------------VAIADFGLCIEGVAN---------------------ISMSSVATPCYSSPEALISK------
    |.|||||||. ||||..  |              . |.||||. .   .                      .|. . ||.. .||.|  .      
---KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEK

----------MYATSADMWSLGVIIYELTTGKRPDFLAGRNPEDVF-----------TKDWKAPLG------------DIYDPDLRLIIGHLLVLDPLER
           | ...|..| |....|. |..|| .  . .|....            |  . |.             .  .|... .. .    || .|
VGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKR

LTAEELFQMT
....|. .  
PSFQEILKRL
Kinase GL50803_3546.AA ULK 19-280 23 1.1e-33 114.94 In-house 1-329 (329) Show / Hide 
Range on Protein: 19-280
Range on HMM: 1-329/329
Sequence Identity: 23% (80 aa)

RDIGRPVGEGSYGTVYSLK---S----SPHKVVKETPIRGLRPSALT--------ALEIEARVLPRME--------HPNIVKYEAIEKTDQF--FFVVMK
  . .  |.||.|.||  .   .        ..|  ..  .. .            |. | ... ..         ||||||.  . .|...  .. .| 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YYPK-SLDQLIKTAIR------SDKSLSPEKIFIIVNQLASGLAYLHSPDKTDSTGKPLPAIIHRDLKPTNILVNSTETE-----------VAIADFGLC
| .   |.|.||.  .        | || ... ..  |...|. .||.             |||||.|| |||..   .            . |||||..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHN-----------IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA

IE-GVA----NISMSSV------ATPCYSSPEALI----SKMYATS-ADMWSLGVIIYELTTGKRPDFLAGRNPEDV---FTKD--W---------KAPL
          .. |. |       || | .|. |      | | .. .|.||||.|.||. .|| | | |  . ...    .|   .         | ||
KHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPP-FYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPL

G-------DIYDPDLRLIIGHLLVLDPLERLTAEELFQMTCF
        ..  |... .|  .|. |. .| . ||||.. .|
QFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_3546.AA Ciliate-E2 19-280 19 1.3e-33 112.71 In-house 1-365 (365) Show / Hide 
Range on Protein: 19-280
Range on HMM: 1-365/365
Sequence Identity: 19% (74 aa)

RDIGRPVGEGSYGTVYSL--KSSPHKV-------------------VKETPIRGLRPSALTALEIEARVLPRME----------------HPNIVKYE-A
 .. .  |.|..|.||    .. ....                   .|.  .  .... . ... | ... ...                ||||.|.  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IE-KTDQFFFVVMKYYPK-SLDQLIK--TAIRSDK-----SLSPEKIFIIVNQLAS---------------GLAYLHSPDKTDSTGKPLPAIIHRDLKPT
 . |.|. .. || |.   .| ..||     |  .     ... ..|  |  |...               .| ||||             |||||.|| 
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHS----------KNNIIHRDIKPE

NILVNSTETEVAIADFGLCIE----------GVANISMSSVA------------------------TPCYSSPEALISKM---------YATSADMWSLG
|||.      . |.||||. .          .. .  .                            || | .|| | .|          | ...|.||||
NILF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG

VIIYELTTGKRPDFLAGRNPEDVFTK-DWKAP-----------------LGDIYDPDLRLIIG---HLLVLDPLERLT-AEELFQMTCF
||.||. .||.|        ..   . ... |                   .. .    ||      .|. || .|.| .|....   |
VILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_3546.AA ULK 19-280 22 2.4e-33 115.67 In-house 1-324 (324) Show / Hide 
Range on Protein: 19-280
Range on HMM: 1-324/324
Sequence Identity: 22% (76 aa)

RDIGRPVGEGSYG-TVYSL---KSSP-HKVVKE--TPIRGLRPSALT--------ALEIEARVLPRME---HPN--IVKYEAIEKTD--QFFFVVMKYYP
  . .  |.||.| .||     |.    ..|.    .. ... . .          |. | ...  .    |||  |||.  . .|.   ... .| | .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

K-SLDQLIKTAIR-----SDKSLSPEKIFIIVNQLASGLAYLHSPDKTDSTGKPLPAIIHRDLKPTNILVNSTETE-----------VAIADFGLCIE-G
   |.|.||.  .       | || ... ..  |...|. .||.             |||||.|| |||..   .            . |||||..    
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHN-----------IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVD

V----ANISMSSV------ATPCYSSPEALI----SKMYATS-ADMWSLGVIIYELTTGKRPDFLAGRNPED----------------VFTKDWKAP---
     ... .. |       || | .|. |      | | .. .|.||||.|.||. .|| | |    |...                . ..  . |   
NNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP

LGDIYDPDLRLIIGHLLVLDPLERLTAEELFQMTCF
 ...  |... .|  .|. |. .| . ||.|.. .|
KDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_3546.AA CMGC 19-225 19 2.5e-28 89.42 In-house 1-341 (513) Show / Hide 
Range on Protein: 19-225
Range on HMM: 1-341/513
Sequence Identity: 19% (68 aa)

RDIGRPVGEGSYGTVYSLKSSPHK-----VVKETPIRGLRPSALTALE----------------------IEARVLPRME-----------------HPN
 .| ...|||.||.||. .    .      .  ..... .  |.  .                        | . | ..                  |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQ-AHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKYEAIEKTDQ-----------------FFFVVMKYYPKSLDQLIKTAIR-----SDKSLSPEK------------IFIIV------NQLASGLA--YL
|||   | ....                  .. |. | ...| |.||   .       . ||. .            |  ..       |.  ||.  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSPDKTDSTGKPLPAIIHRDLKPTNILVNSTETE-------------------VAIADFGLCI-EGVA----------------------NISMSSVATP
|| ..          |||||||| |||.|.. .                    . |.||||.  ...                           . |.| 
HSHWG---------NIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTR

CYSSPEALI-SKMYA---------TSADMWSLGVIIYELTTG-------KRP
 | .|| |. .| |          |. ||||.| |..|. ||       ..|
WYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKP
Kinase GL50803_3546.AA STE 19-280 20 5.6e-27 92.35 In-house 1-359 (359) Show / Hide 
Range on Protein: 19-280
Range on HMM: 1-359/359
Sequence Identity: 20% (79 aa)

RDIGRPVGEGSYGTVYSLKSS-PH-----------------KVVKETPIRGLRP---------------SALTALEIEARVLPRME--HPNIVKYEAIEK
 .. . .|.|..||||  .   ..                   .|. ...  ..               . .  .. | ... ..   |||||||   . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TD-------QFFFVVMKYYP-KSLDQLIKTAIRSDKSLS---------PEKIF-IIVNQLASG-LAYLHSPDKTDSTGKPLPAIIHRDLKPTNILVNSTE
 .       .  ...| | .  |||..||.     |.|.         ||..  .|. |.  | |.||||          .  |||||.|| |||.    
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHS----------HH-IIHRDIKPANILL----

TEVAIADFGLCIEGVAN------------------ISMSSVATPCYSSPEALIS------KMYATSADMWSLGVIIYELTTGKRPDFLAGRNPEDVFTKD
  | ..|||.|   . .                   . . | || . .|| .        | | |..|.||||  | |. ||| | .  . ...  | . 
--VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP-WHDMHPMRAMFMIP

----------------WKAP--LGD------------------IYDPDLRLIIGHLLVLDPLERLTAEELFQ--MTCF
                 . |    .                   . |...  | . |. || .| ||..| .     .
FNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_3546.AA Ciliate-E2-Unclassified 72-225 26 5.4e-26 87.18 In-house 80-269 (352) Show / Hide 
Range on Protein: 72-225
Range on HMM: 80-269/352
Sequence Identity: 26% (53 aa)

HPNIVKYEAIEKTDQFFFVVMKYYP-KSLDQLIK-------------TAIRSDKSLSPEKIF-----IIVNQLASGLAYLHSPDKTDSTGKPLPAIIHRD
||.|||.. .....| .. || | . ..| | ||               ....| .. ...       .  |. .|| |||.  .          |||||
HPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNN----------IIHRD

LKPTNILVNSTET--EVAIADFGLCI--------EGVA----------NISMSSVATPCYS----SPEALISKMYATS----ADMWSLGVIIYELTTGKR
.|| |||...     .. |.|||...        .             ... . . ||.|     .|| | .. | .|    .|.||||||.||. .|..
IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY

P
|
P
Kinase GL50803_3546.AA TKL-Unique 21-225 24 7e-25 84.77 In-house 1-233 (290) Show / Hide 
Range on Protein: 21-225
Range on HMM: 1-233/290
Sequence Identity: 24% (59 aa)

IGRPVGEGSYGTVYSLKS--SPHKVVKETPIRGLRPSALTALEIEARVLPRME-HPNIVKYEAIEK----TDQFFFVVMKYYPK-SLDQLIKT------A
..  .|||.||.||  |   .|  .... |  ..... .  .| | ... . . |||||.| .. .    .   .. || |.|  ||. .. .       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

IRSDKSLSPEKIFIIVNQLASGLAYLHSPDKTDSTGKPLPAIIHRDLKPTNILVNST----ETEVAIADFGLCIEGVANISMSSV-----------ATPC
 .. . |.....  .... |.|. |||. ..        | |||||||..|.||..     |  . |.||||..    .. |..            ... 
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEP--------P-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFR

YSSPEALIS--KMYATSADMWSLGVIIYELTTGKR------P
...|| | .  ..| ...| .| |.. .|. |.|.      |
WMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase GL50803_3546.AA CAMK 148-280 19 1.9e-20 61.93 In-house 200-425 (425) Show / Hide 
Range on Protein: 148-280
Range on HMM: 200-425/425
Sequence Identity: 19% (45 aa)

IIHRDLKPTNILVNSTE----------------TEVAIADFGLCIEGVANI-------------------------SMSSVATPCYSS-PEALISKM---
|.|||||| |||... .                  . |.|||. ..   .                             .. ||.| . || | .|    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YATSADMWSLGVIIYELTTGKRPDFLA------------GRNPEDVFTKDWKAPLG-DIYD-------------------------PDL
           |  ..||||.||| | . .|. | | .            | |... | |  |.    . .                          .. 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPP-FYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

RLIIGHLLVLDPLERLTAEELFQMTCF
.  | ..|. || .|.|.|.  .   .
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_3546.AA NEK 20-174 27 6.7e-14 45.7 In-house 2-169 (286) Show / Hide 
Range on Protein: 20-174
Range on HMM: 2-169/286
Sequence Identity: 27% (49 aa)

DIGRPVGEGSYGTVYSLKS---SPH-----KVVKETPIRGLRPSALTALE-IEARVLPRMEHPNIVKY-EAIEKTD-QFFFVVMKYYPK--SLDQL---I
.| . .|.||.|.||  ..   . |      | |.  . .. .    ..   |.|.| .. ||||||| ....  . .... || |      |.|.   |
EIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSI

KTAIRSDKSLSPEKIFIIVNQLASGLAYLHSPDKTDSTGKPLP--AIIHRDLKPTNILVNSTETE---VAIADFGL
|    . | .. |.|  .  |....| |.|.        | .|   |.|||.|| ||  ..  ..   | | |||.
KKQKQKGKYFEEEQIWDWFIQMCLALKYMHDR-------K-GPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGI
Kinase GL50803_3546.AA NEK 189-280 29 1.2e-13 44.77 In-house 187-286 (286) Show / Hide 
Range on Protein: 189-280
Range on HMM: 187-286/286
Sequence Identity: 29% (30 aa)

TPCYSSPEALISKMYATSADMWSLGVIIYELTTG--KRPDFLAGR--NPEDVF---TKD-WKAPLGDI--YDPDLRLIIGHLLVLDPLERLTAEELFQMT
||.| ||| . .| |   .|.||||...||. |   |.|    .   | .  .   .|    .|. .   | .||. .|  .|  || .| .......| 
TPYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHP--FEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMP

CF
. 
FI
Kinase GL50803_3546.AA TyrKc 19-280 20 6.8e-13 -14.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-280
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

RDIGRPVGEGSYGTVY-----------SLKSSPHKVVKETPIRGLRPSALTALEIEARVLPRM--EHPNIVKYEAIEKTD-------QFFFVVMKYYPK-
   |.  ||| .|.||           .||..                 . ..  |||.. .   .|||||.  ..  ..       .  ..|| | |. 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

SLDQLIKTAIRSDKSLSPEKIFIIVNQLASGLAYLHSPDKTDSTGKPLPAIIHRDLKPTNILVNSTETEVAIADFGLCIEGVAN---------ISMSS-V
.|.. ..   .    |....   .  | |.| .||||             .|||||   |.||..    | |.||||. ..            .....  
DLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSK-----------NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHK

ATP--C---YSSPEALISKMYATSADMWSLGVIIYELTTGKRPDFLAG----RNPEDVFTKDWKA---PLGDI--------YDPDLRLIIGHLLVLDPLE
 .         .||..  ... |  | || || ..|. |   .          ....|. .  .    |  .           ...  |.      || .
GGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED

RLTAEELFQMTCF
| | .|.    ||
RPTFSEI--HECF
Kinase GL50803_3546.AA CAMK 24-134 12 5e-11 31.04 In-house 1-197 (425) Show / Hide 
Range on Protein: 24-134
Range on HMM: 1-197/425
Sequence Identity: 12% (24 aa)

PVGEGSYGTVYSLKSSPHK---------------VVKETPIRGLR--------------------------PSALTALEIEARVLPR-------MEHPNI
  |.||.|.|.  .    .                .|  . . |.                          |. .  .. | ... .       . ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYEA---------------IEKT-----DQFFFVVM---KYYPKS------LDQLIKT-----------AIRSDKSLSPEKIFIIVNQLASGLAYLHS
.|                    ..     |.... ||    | .        .| ...             . ... .. .    .. |..|...|.||
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHS
Kinase GL50803_3546.AA Pkinase_Tyr 63-225 26 8.3e-05 16.91 Pfam 53-214 (270) Show / Hide 
Range on Protein: 63-225
Range on HMM: 53-214/270
Sequence Identity: 26% (46 aa)

EARVLPRM-EHPNIVKYEAIEK-TDQF--FFVVMKYYPK-SLDQLIKTAIRSDKSLSPEKIFIIVNQLASGLAYLHSPDKTDSTGKPLPAIIHRDLKPTN
||...  .  |||||.. ..    ..    ..|| | |. .|.   ..   ....|... .  .  | |.|..||.|             .|||||   |
EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-----------CIHRDLAARN

ILVNSTETEVAIADFGLCIEGVANISMS-SVAT-----PCYSSPEALISKMYATSADMWSLGVIIYELTT-GKRP
.||...   | |.||||.     | .    ...         .||..  . . |  | || || ..|. | |. |
CLVTENN-VVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase GL50803_3546.AA CMGC 260-280 42 0.001127 6.92 In-house 493-513 (513) Show / Hide 
Range on Protein: 260-280
Range on HMM: 493-513/513
Sequence Identity: 42% (9 aa)

LLVLDPLERLTAEELFQMTCF
.|..|| .|.|||.  |.  |
MLQYDPDKRITAEQALQHPYF
Kinase GL50803_3546.AA TKL 25-34 50 0.023115 4.33 In-house 1-10 (364) Show / Hide 
Range on Protein: 25-34
Range on HMM: 1-10/364
Sequence Identity: 50% (5 aa)

VGEGSYGTVY
.|.|..|.||
IGSGGFGEVY
Ank GL50803_3546.AA Ank 357-378 40 2.4e-05 23.57 Pfam 1-22 (33) Show / Hide 
Range on Protein: 357-378
Range on HMM: 1-22/33
Sequence Identity: 40% (9 aa)

SGMTALMIAAECGNLDAVRLLL
 |.|.|..|..||... |..||
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_3546.AA Ank 324-356 24 26.051839 1.77 Pfam 1-33 (33) Show / Hide 
Range on Protein: 324-356
Range on HMM: 1-33/33
Sequence Identity: 24% (8 aa)

TGETQLMQSVRRGNKEGLRELIENSQGFGAKNA
 |.| |.  .|.|..| ...|...     |.. 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_3546.AA Ank 388-418 24 0.025101 12.65 Pfam 1-33 (33) Show / Hide 
Range on Protein: 388-418
Range on HMM: 1-33/33
Sequence Identity: 24% (8 aa)

CGRTALMYATKNAQLAAAKELLA--VEAGKRDK
.|.|.|..| .. ..  .|.||    .   .|.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_3546.AA Ank 419-439 38 0.031386 12.3 Pfam 1-21 (33) Show / Hide 
Range on Protein: 419-439
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

SGKSALMLAAEGGSAELVALL
 | ..|.||.. |..| | .|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_3546.AA Ank 450-473 33 0.018125 13.16 Pfam 1-24 (33) Show / Hide 
Range on Protein: 450-473
Range on HMM: 1-24/33
Sequence Identity: 33% (8 aa)

SGMTALMIAVKKGFISAVEILAEH
 |.|.|..|...| .. |. | .|
DGFTPLHLACRCGHTEVVKMLLQH
Ank GL50803_3546.AA Ank 481-501 33 18.111039 2.34 Pfam 1-21 (33) Show / Hide 
Range on Protein: 481-501
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

AGRTALSHAIRFKQRPVIDLL
 |.|.|  |.|  .  |. .|
DGFTPLHLACRCGHTEVVKML