Gene GL50803_9289 (G.lamblia)

GL50803_9289

Species: G.lamblia
Alias: GL50803_9289, GK166
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_9289.AA Protein None 627 None Fasta, JSON
GL50803_9289.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of GL50803_9289.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_9289.AA NEK 9-275 35 3.1e-81 276.21 In-house 1-286 (286) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-286/286
Sequence Identity: 35% (103 aa)

YESLGLIGQGGFGKVYKVRSLKTNEI-----FACKEIDYGCLSDKYKEIQD-NELKLLISLKHPNIVHFTNVYKDPVNEVYYMLMEFCD-KGDLSDL---
|| .  |||| ||||||||. ... .     .. |.|..|..|.| |.    || ..| .||||||| . . . .  |.  .  ||.|. .|||...   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IKHYRRARKDIPESTIWIFAYQLLNALEYCHSP--FKENCPNMGRVVHRDIKPENILRAGEVT----VKFADFGICRTIGDG-IMATT-NVGTTCYMAPE
||... ..| ..|..|| . .|.. || |.|.           ....|||||| ||    . .    ||  |||| .  ...  ||.|  ||| .||.||
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGP------QRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPE

LLKGQEYNEKIDIWALGCALYELCTK--QRMFVGK---GTDVVLKQIDE-LPRPLHLDN-YSQELCLFIDMMLTVDFSKRPAANELLRYPKI
..... ||.| |||.||| |||.||    . | ..       ..| . .  . |..  . |||.|  .| .||..| ..|| .|..|  | |
VCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_9289.AA S_TKc 9-275 36 1.8e-78 267.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-231/231
Sequence Identity: 36% (102 aa)

YESLGLIGQGGFGKVYKVRSLKTNEIFACKEIDYGCLSDKYKEIQDNELKLLISLKHPNIVHFTNVYKDPVNEVYYMLMEFCDK--GDLSDLIKHYRRAR
|| | .||.|.||||||.|  ||..|.|.|.|.         |   .|...| . .|||||..  |. |   . .|| ||.||   ||| |.||...| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

KD--IPESTIWIFAYQLLNALEYCHSPFKENCPNMGRVVHRDIKPENILRAGEVTVKFADFGICRTIGDGIMATTNVGTTCYMAPELLKGQEYNE-KIDI
..  .|| ... ..||...|||||||        . ...|||.||||||     ..| .|||..| .      || .||  |||||.|    |.  |.|.
LRFPFPE-HARFYMYQICCALEYCHS--------H-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDW

WALGCALYELCTKQRMFVGKGTDVVLKQIDELPRPLHLDNYSQELCLFIDMMLTVDFSKRPAANELLR-------YPKI
|..|| |||... .  |     ....|.|            |.|.. ||. .|..| .||| | |.|.        | .
WSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_9289.AA Pkinase 9-275 29 7.6e-66 229.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

YESLGLIGQGGFGKVYKVRSLKTNEIFACKEIDYGCLSDKYKEIQDN--ELKLLISLKHPNIVHFTNVYKDPVNEVYYMLMEFCDKG----DLSDLIKHY
|. .. ||.|.||.||| .  .|..|.|.|.|..   ... ...  .  |.... .|.||||| .  .. |  .  .|| ||.|..|    ||.|.|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

RRARKDI--PESTIWIFAYQLLNALEYCHSPFKENCPNMGRVVHRDIKPENILRAGEVTV----KFADFGICRT--IGDGIMATTNVGTTCYMAPELLK-
 .... .  .| ..  ..||.| .||||||          ...|||.||||||   . ..    | .|||...   .  .  .|| .||  |||||... 
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

GQEYNEKIDIWALGCALYELCTKQRMFVGK------GTDVVLKQIDELPRPLHLDNYS--------------------QELCLFIDMMLTVDFSKRPAAN
||.|  |.|.|..|| |||.....  | |.        ......| . | . . .. .                    .|.. ||. .|..| .||| | 
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

ELLRYPKI
..|  | .
QILQHPWF
Kinase GL50803_9289.AA STE 9-275 26 3.8e-64 219.43 In-house 1-359 (359) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-359/359
Sequence Identity: 26% (99 aa)

YESLGLIGQGGFGKVYKVRSLK---------------TNEIFACKEIDY-GC-----------LSDKYKEIQD---NELKLLISLK--HPNIVHFTNVYK
.| .. ||.|.||.||| .  |               |.||.| |....  |           |..| .|...   .|.|..  ..  |||||..   | 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----DPVNEVYYMLMEFCDKGDLSDLIKHYRRARKD----------IPESTIWIFAYQLLNA-LEYCHSPFKENCPNMGRVVHRDIKPENILRAGEVTV
     .  ..  .. ||..| | |.|.|||.    |.          .||| | ....|.| . |.| ||        .. ..|||||| |||      |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHS--------HH-IIHRDIKPANILL-----V

KFADFGICRTIGD-----------------GIMATTNVGTTCYMAPELLKG------QEYNEKIDIWALGCAL-------YELCTKQRM----FVGKG--
| .|||.|  . |                 . . .| |||  .|||| ...      ..|..| ||| ||| .       ..... . |       ..  
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

----TDVVLKQIDELPRPL--HLD----------------NYSQELCLFIDMMLTVDFSKRPAANELLR--YPKI
     ... ..... | ||  ||.                ..|.|.. ||.  |. | .||| |..||.   | |
MQQQFEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_9289.AA NEK2 9-215 34 1.9e-62 209.09 In-house 1-259 (319) Show / Hide 
Range on Protein: 9-215
Range on HMM: 1-259/319
Sequence Identity: 34% (89 aa)

YESLGLIGQGGFGKVYKVRSLKTNEIFACKEIDYGCLSDKYKEIQDNELKLLISLKHPNIVHFTNVYKDPVNEVYYMLMEFCDKGDLSDLIKHYRRARKD
|| |. ||.| ||...|||   . .|.. |||.|| .  | .    .|  .|  ||||||| . .   |  |.. |. ||.|  |||| .||..|  |. 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

IPESTIWIFAYQLLNALEYCHS------------PFKENCPNMGRVVHRDIKPENILRAGEVT-------------------------------------
..|. ||    ||. ||  ||               |   .. . . |||||| ||    .                                       
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--VKFADFGICRTIG-DGIMATTNVGTTCYMAPELLKGQEYNEKIDIWALGCALYELCT
  ||  |||  |    |   |.| |||  || ||...|| |||| |||..|| .||.|.
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCA
Kinase GL50803_9289.AA ULK 9-263 29 5.4e-59 202.31 In-house 1-317 (329) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-317/329
Sequence Identity: 29% (95 aa)

YESLGLIGQGGFGKVYKVRSLKT----NEIFACKEIDYGCLSDKYKE--------IQDNELKLLISLK--------HPNIVHFTNVYKDPVNEVYYMLME
|.    .|.| |||||| |  ||    ||..||| ||   .. |..|          .|| |..  ||        ||||| .  ..... .  .|. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCDKGDLSDLIKHYRR------ARKDIPESTIWIFAYQLLNALEYCHSPFKENCPNMGRVVHRDIKPENILRAGEV------------TVKFADFGICRT
.|. |||...|| ...        | ..|. . .| .|.||.. . |.          ...||||||.|||    .            ..| |||| ...
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK---------HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKH

IGDG----IMATTNV------GTTCYMAPELLK----GQEYN-EKIDIWALGCALYELCTKQRMFVGKGTDVVLKQIDEL------------PRPLHLD-
. ..     |..| |      ||  ||||..|.    ...|.  | ||| ||| .||. . .  |..  .| .|..| .|             .||  . 
VDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPK

-----NYSQELCLFIDMMLTVDFSKR
     . |.|.  .|  ||..| ..|
DGNDPQISPECKDLIRRMLQYDEKDR
Kinase GL50803_9289.AA ULK 9-263 28 7.2e-58 198.56 In-house 1-312 (324) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-312/324
Sequence Identity: 28% (91 aa)

YESLGLIGQGGFG-KVYKVRSLKT---NEIFACKEIDYGCLSDKYKE--------IQDNELKLLISLK---HPN--IVHFTNVYKDPVNEVYYMLMEFCD
|.    .|.| || |||| |  ||   |...||| ||   ...|..|         ..|| ...  ||   |||  || .  ..... .  .|. ||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

KGDLSDLIKHYRR-----ARKDIPESTIWIFAYQLLNALEYCHSPFKENCPNMGRVVHRDIKPENILRAGEV------------TVKFADFGICRTIGDG
 |||...|| ...       | ..|. . .| .|..|.. . |.           ..||||||.|||    .            ..| |||| .... ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHK---------HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNN

----IMATTNV------GTTCYMAPELLK----GQEYN-EKIDIWALGCALYELCTKQRMFVGKGTDVVLKQIDEL------------PRPLHLD-----
     | .| |      ||  ||||..|.    ...|.  | ||| ||| .||. . .  |..  .| .|. | .|             .|.  .     
NMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKD

-NYSQELCLFIDMMLTVDFSKR
 . |.|.  .|  ||..| ..|
PKISPECKDLIRRMLQYDEKDR
Kinase GL50803_9289.AA Ciliate-E2 9-275 24 3.9e-53 180.74 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-365/365
Sequence Identity: 24% (96 aa)

YESLGLIGQGGFGKVYKVRSLKTNEIFACKEIDYGC-------------------LSDKYKEIQDNELKLLI----------------SLKHPNIVHFTN
|. . .||||.||.|||..  |... || | ||                      .. . .|.. .|....                 .|.||||. .  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VYKDPVNEVYYMLMEFCDKGDLSDLIKHYRRARKDIPE-------STIWIFAYQLLN---------------ALEYCHSPFKENCPNMGRVVHRDIKPEN
....  .. .|. ||.|. ||| |.||. .  |. ..|         |  . .|.|.               ||||.||         ....||||||||
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHS--------KNNIIHRDIKPEN

ILRAGEVTVKFADFGICRTIGDG--------------------------------IMATTNVGTTCYMAPELLKGQE---------YNEKIDIWALGCAL
||      .| .|||... . |                                  |. | .||  ||||| |.|..         |..|.|||.||. |
ILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

YELCTKQRMFVGKGTDVVLKQIDE----LPRPL-------------HLDNYSQELCLFIDM----MLTVDFSKRPA-ANELLRYPKI
||...... |        ..|| .    .| |                .. |||   .|      || .| .||.  ....|  | .
YEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_9289.AA Ciliate-E2-Unclassified 9-275 24 2.5e-50 172.79 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-352/352
Sequence Identity: 24% (90 aa)

YESLGLIGQGGFGKVYKVRSLKTNEIF-----ACKEIDYGCLSDKYK------EIQDNELK-------------LLISLKHPNIVHFTNVYKDPVNEVYY
|. .  |||||||||||..  |..  .     ..| ..|  .. ..|      ... |..|             .|....||.||..  . .|  |   |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN--IY

MLMEFCDKGDLSDLIKHY-------------RRARKDIPESTIW-----IFAYQLLNALEYCHSPFKENCPNMGRVVHRDIKPENILRAGEV---TVKFA
. ||.|. |||.. ||..             .. || ..|  .       ...|.|..|||.|.         . ..||||||||||   .     .| .
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHH--------KNNIIHRDIKPENILFDNNGKNYYIKII

DFGICRTIGDG----------------IMATTNVGTTCYM----APELLKGQEYN----EKIDIWALGCALYELCTKQRMFVGKGTDV------------
||||.. ...                  |..|..|| .||    |||.|.||.|.    .|.|||.||. |||... .. | ..  .             
DFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNA

----VLKQI--DELPRPL--------HLDNYSQELCL-FIDMMLTVDFSKRPAANELLRYPKI
    ....|   ..  |         |...  ....  ..  || .. .||. ....|  | .
YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_9289.AA CAMK 14-211 21 3.8e-49 156.1 In-house 1-325 (425) Show / Hide 
Range on Protein: 14-211
Range on HMM: 1-325/425
Sequence Identity: 21% (73 aa)

LIGQGGFGKVYKVRSLKTN------------EIFACKEIDYGCLSD------------------------KYKEIQ--DNELKLLIS-------LKHPNI
 .|.|.||||....  .|.            . .|.| ||   |.|                        . |  .   .|.... .       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VHFTNVYKDPV-----------------NEVYYMLM---EFCDKG----DLSDLIKHYRR----------ARKD--IPESTIWIFAYQLLNALEYCHSPF
...  || ||                  .. .|| |   |.|. |    || | |.  ..          . ..  ..|.    .  |.. |..||||  
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHS--

KENCPNMGRVVHRDIKPENILRAGE-----------------VTVKFADFGICRTIGD------------------------GIMATTNVGTTCYMA-PE
      .. .||||.||||||                      ..| .|||  . . .                        | . .| .|| .||| ||
------HN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE

LLKG--------------QEYNEKIDIWALGCALY
.|.|              . |..|.|.|..|. ||
VLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY
Kinase GL50803_9289.AA NEK1 9-275 31 3e-47 161.93 In-house 1-276 (276) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-276/276
Sequence Identity: 31% (91 aa)

YESLGLIGQGGFGKVYKVRSLKTNEIFACKEIDYGCLSDKYKEIQDNELKLLISLKHPNIVHFTNVYKDPVNEVYYMLMEFCDKGDLSDLIKHYRRARKD
|. .  ||.| |||...|..   .  .. |||   . ..| .|   || ..|  .|||||| . .      . ..|  ||.|| |||   |.  .|  | 
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

IPESTIWIFAYQLLNALEYCHSPFKENCPNMGRVVHRDIKPENILRA---GEV--------------TVKFADFGICRTIGDGIM-ATTNVGTTCYMAPE
..| .|  .  |.  || . |.          .. |||||. ||      .                .|| .|||| |.  .    | | .||  |  ||
FSEDQIMHWFCQICLALNHIHD---------RKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPE

LLKGQEYNEKIDIWALGCALYELCTKQRMFVG-KGTDVVLKQIDELPRPLHLDNYSQELCLFIDMMLTVDFSKRPAANELLRYPKI
.   . || | |||.||| ||||||  . | . . .  |||..  .  |.    ||.||   .  |. .. . || .| .|  | |
ICQNKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPP-HYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase GL50803_9289.AA CMGC 9-223 21 9.3e-46 147.78 In-house 1-346 (513) Show / Hide 
Range on Protein: 9-223
Range on HMM: 1-346/513
Sequence Identity: 21% (77 aa)

YESLGLIGQGGFGKVYKVRS--------------LKTNEIFACKEIDYGCLSDKYKEIQD-------------NELKLLISLK-----------------
|| .. ||.| .|.||| |                .|||| | | |     ...|.| .               |.|.|  |.                 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKI----KNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKH

HPNIVHFTNVYKDPV---------------NEVYYMLMEFCDKGDLSDLIKHYR------------------------RARKDIPESTIWIFAYQLLNAL
|.|||.  ......                ..  |. .|..|. || ..||...                        .  | ..   |  ..||.|..|
HNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGL

E--YCHSPFKENCPNMGRVVHRDIKPENILRAGE--------------------VTVKFADFGICRTIGDG---------------------IMATT-NV
.  ||||  .       ...|||.||||||   .                     ..| .||| .| ...                       .. | .|
KLKYCHSHWG-------NIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYV

GTTCYMAPELLKGQE----------YNEKIDIWALGCALYELCTK--------QRMFVGK
 |  | |||.| | .          |...||.|..|| ..|. |.        . .| |.
VTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGH
Kinase GL50803_9289.AA TyrKc 9-275 21 1.4e-15 29.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

YESLGLIGQGGFGKVYKVRSLKTNEIFACKEIDYGCLSDKYKEIQDNELKLLISL--KHPNIVHFTNVYKDP-----VNEVYYMLMEFCDKGDLSDLIKH
 . .  .| | ||.||| .     .  | | .  ..     ... . |.... .|  .||||| .  |  ..       | ....||....||| | .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMR-EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

YRRARKDIPESTIWIFAYQLLNALEYCHSPFKENCPNMGRVVHRDIKPENILRAGEVTVKFADFGICRTIGDG--------IMAT-----TN-VGTTCYM
.|.    .. ..   |..|  .  || ||          ...|||.   |.| . . ||| .||| .| |.|.           .     .. .     |
HRPK---LCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

APELLKGQEYNEKIDIWALGCALYELCTK-QRMFVG-----KGTDVVLKQIDELPRPLHLDN--------YSQELCLFIDMMLTVDFSKRPAANELLRYP
||| ..  ....| |.|. |  ..|..|  |    |     .  . |......  |.   .|         ..|.   . .    | ..||  .|.  . 
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HE

KI
..
CF
Kinase GL50803_9289.AA NEK2 244-275 40 2.2e-08 24.18 In-house 288-319 (319) Show / Hide 
Range on Protein: 244-275
Range on HMM: 288-319/319
Sequence Identity: 40% (13 aa)

YSQELCLFIDMMLTVDFSKRPAANELLRYPKI
||..|   |  |. || ..||  .|.|..| |
YSRHLNEIIHFMINVDHYHRPSIEEILQHPQI
Kinase GL50803_9289.AA CAMK 240-275 36 0.000269 8.96 In-house 391-425 (425) Show / Hide 
Range on Protein: 240-275
Range on HMM: 391-425/425
Sequence Identity: 36% (13 aa)

HLDNYSQELCLFIDMMLTVDFSKRPAANELLRYPKI
|  . |||   .|  ||.|| .||. . . |. | .
HH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_9289.AA Pkinase_Tyr 159-215 29 0.000519 14.21 Pfam 149-209 (270) Show / Hide 
Range on Protein: 159-215
Range on HMM: 149-209/270
Sequence Identity: 29% (18 aa)

TVKFADFGICRTI-GDG---IMATTNVGTTCYMAPELLKGQEYNEKIDIWALGCALYELCT
.|| .||| .|.|  |.    ...        |||| ..  ....| |.|. |  ..|..|
VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFT
Kinase GL50803_9289.AA CMGC 251-275 32 0.00159 6.42 In-house 489-513 (513) Show / Hide 
Range on Protein: 251-275
Range on HMM: 489-513/513
Sequence Identity: 32% (8 aa)

FIDMMLTVDFSKRPAANELLRYPKI
... ||. | .||. | . |. | .
LLKKMLQYDPDKRITAEQALQHPYF
Kinase GL50803_9289.AA Pkinase_Tyr 55-97 36 0.013647 9.4 Pfam 52-96 (270) Show / Hide 
Range on Protein: 55-97
Range on HMM: 52-96/270
Sequence Identity: 36% (17 aa)

NELKLLISL-KHPNIVHFTNVYK---DPVNEVYYMLMEFCDKGDLSD
.|.|.. .| .||||| .  |     .|    .|. ||.. .||| |
REAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLD
Ank GL50803_9289.AA Ank 390-407 44 0.005528 15.02 Pfam 1-18 (33) Show / Hide 
Range on Protein: 390-407
Range on HMM: 1-18/33
Sequence Identity: 44% (8 aa)

YGNTPLMLAAASGNLASV
.|.|||.||. .|..  |
DGFTPLHLACRCGHTEVV
Ank GL50803_9289.AA Ank 421-451 30 8e-06 25.28 Pfam 1-33 (33) Show / Hide 
Range on Protein: 421-451
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

DCKTALMMAAENNHLQIVRFLLE--AEAGKTTD
|  |.|..|....|...|..||.  |.   ..|
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_9289.AA Ank 452-477 38 0.00082 18.01 Pfam 1-26 (33) Show / Hide 
Range on Protein: 452-477
Range on HMM: 1-26/33
Sequence Identity: 38% (10 aa)

VGDTALIIAATQGHTSIVELLVEYEA
 |.|.| .|.  |||..|..|... |
DGFTPLHLACRCGHTEVVKMLLQHGA
Ank GL50803_9289.AA Ank 483-503 33 0.044589 11.75 Pfam 1-21 (33) Show / Hide 
Range on Protein: 483-503
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

AGWTALMKAATGDHHRVARLL
 |.|.|. |.  .|..|...|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_9289.AA Ank 514-536 26 0.000925 17.82 Pfam 1-23 (33) Show / Hide 
Range on Protein: 514-536
Range on HMM: 1-23/33
Sequence Identity: 26% (6 aa)

NGLTALMIAAAMNSEGVLQELIE
.| |.|..|. .... |...|..
DGFTPLHLACRCGHTEVVKMLLQ
Ank GL50803_9289.AA Ank 545-565 42 0.066666 11.12 Pfam 1-21 (33) Show / Hide 
Range on Protein: 545-565
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

EGKTALIFATINGHLQLVKWL
.| |.|  | ..||.. ||.|
DGFTPLHLACRCGHTEVVKML