Gene CG2309 (Fruit Fly)

CG2309

Species: Fruit Fly
Alias: CG2309, SFO139, ERK7
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 8D4,

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
CG2309.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 295 Kinase domain by global Sugen HMM Fasta, JSON
CG2309.AA Protein Various 878 None Fasta, JSON

Protein domain

Protein domains of CG2309.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG2309.AA ERK7 25-319 62 7e-209 700.23 In-house 1-292 (292) Show / Hide 
Range on Protein: 25-319
Range on HMM: 1-292/292
Sequence Identity: 62% (184 aa)

FDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNLDFYLVFEFMESDLHNVIKRGNVLKDV
...|||.|||||||||||.|.|||..|||||.|||||..||||||.||..||..|.|||||.||.....|.|..|.||||||||.|||.||..||.|||.
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDI

HKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRNYTKGIDMWGLGCILG
||...||||..|||..||||||||||||||||.||.|..||.||||||.......|   ||..|||.|||||||||||||..|..||||.|||..|||||
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEY--DEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

EMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYV
||.|.||.|.||||.||||||....|..|. ||..||.......|.... ...|..||.||..||||.|.|.|.|||.||..||||..|..||||
EMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN-QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase CG2309.AA MAPK 25-319 37 1e-159 536.9 In-house 1-328 (328) Show / Hide 
Range on Protein: 25-319
Range on HMM: 1-328/328
Sequence Identity: 37% (124 aa)

FDVRKRMGKGAYGIVWKATDRR------TKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKAS-----NN----LDFYLVFEFMES
..  |. |.||||.|..|.|.|      ....||.||....|...|...|||||...|| |..|.||..| |||...     |.     |.|.|.|.||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLHNVIKRGNVLKDVHKRFVMYQLINA--IKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDG------MLTDYVATRWYRAP
|||..||... | | |... |||....  .|.|||.|||||||||||||... | ||..||||||.. .   ..  ..|.      ..|.||||||||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EILVA--SRNYTKGIDMWGLGCILGEMIR-QKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIG-PSFGSVLLSRNI--QRDRRYSLDEMMKN----CCDD
||.    ...|||..||| .|||..||.. .||||.|.....|...|.  |.. .. .|  |. ..    .....   ..  ......| .|    ....
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

GISLVKALLVLNPHNRLTAKEAIRHPYV
 | |.. .||..|. |.|..||..|||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CG2309.AA CMGC 25-319 23 5.5e-127 419.67 In-house 1-513 (513) Show / Hide 
Range on Protein: 25-319
Range on HMM: 1-513/513
Sequence Identity: 23% (119 aa)

FDVRKRMGKGAYGIVWKATD--------------RRTKNTVALKKVFDAFRDETDAQ----------RTYREVIFLRAFR----------------CHPN
... |. |.|.||.|.|..|              ..|.. ||.||.. .| .|..|.          |..||. .|. ..                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVRLVDIFKASN---------------NLDFYLVFEFMESDLHNVIKRGN---------VLKDVH------------KRFVM------YQLINAIK--FI
||.| |||. .|               . ..|||||.|. ||...||. .          |.. |            ... |      ||.....|  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSGN--VIHRDLKPSNILIDSKCRL--------------------KVADFGLARTLSSRRIY--------------DDLEQDGMLTDYVATRWYRAPEIL
|| .  .|||||||.||||...|.|                    |..|||||| ....                 || .   ..|.||.||||||||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD-KPNRPYTHYVVTRWYRAPEIL

VASRNYT---------KGIDMWGLGCILGEMIRQ--------KPLFQ-----------GTSTVNQIEKIVTSLPNV----------------TKLDIASI
. ...||         ..||||..|||..||..         ||||.           |.|...|..||.  | .                 .. ..  |
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

G--------------------PSFGSVLLSRNIQRDRRY--SLDEMMKN-----------------------------------CCDDGISLVKALLVLN
.                    ..|.   ...|..  ...  .. .....                                   |....| |.| .|...
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PHNRLTAKEAIRHPYV
|..|.||..| .||| 
PDKRITAEQALQHPYF
Kinase CG2309.AA S_TKc 25-319 27 1.9e-93 317.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-319
Range on HMM: 1-231/231
Sequence Identity: 27% (87 aa)

FDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNLDFYLVFEFMES---DLHNVIKRGNV-
... .  ||||.| |.|.....|.  ||.|..          ....||.  |.    |||||.| |.|      ..|.|.|...    ||. .||. .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRNYTK-GI
     .   | ||.|||...|....|| ..|||||||.|||.|.  ..|..|||||| |               | .. |.||.|||.|     |.|  .
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL----GYGKCKC

DMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAI
|.| .|||| ||.  .|.|.   ..... |..                                           ........ .|. .| .|.|| || 
DWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EAL

R-------HPYV
.       ||..
QDEWDIKCHPWF
Kinase CG2309.AA ERK 25-245 44 3.4e-93 315.9 In-house 1-229 (307) Show / Hide 
Range on Protein: 25-245
Range on HMM: 1-229/307
Sequence Identity: 44% (104 aa)

FDVRKRMGKGAYGIVWKATDRR-----TKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKAS---NNLDFYLVFEFMESDLHNVIK
.   |. |.||||.| .|.|       | ..|| ||...|| .. .. ||.||  .|| |. |.||. | ||.. .   .  | |.|.|.||.||| .|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

RGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLAR----TLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRNYTK
  . | | |  . |||.....|.||| |||||||||||||. | | ||..||||||    . ...      ......|.||||||||||||.   ..|||
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHE----CNQNFMTEYVATRWYRAPEIMLSWQKYTK

GIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKI
 .|.|  |||. ||.. ||||.| ..|.||. |
AMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRI
Kinase CG2309.AA CDK 25-245 34 6.2e-85 271.66 In-house 1-237 (284) Show / Hide 
Range on Protein: 25-245
Range on HMM: 1-237/284
Sequence Identity: 34% (87 aa)

FDVRKRMGKGAYGIVWKATDRRTK-----NTVALKKVFDAF-----RDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNL---------DFYLVFE
..  .. | |.||.| || |..|.     . |||||.          .|   . . ||.  |.    |||||.| |..  .|            .|.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

FMESDLHNVIKRGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCR-----LKVADFGLARTLSSRRIYDDLEQDG-M--LTDYVATRW
.|. ||  ...          .  |.||.... ..|| ...||||||.||||...       ||.|||||||  ....     .. . .  .|  | |.|
YMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQ----MS-EPNRTYTHEVVTLW

YRAPEILVASRNYT--KGIDMWGLGCILGEMIR---QKPLFQGTSTVNQIEKI
|||||.|  |..|.   .||||..|||..||..    ||||.|.|  .|..||
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKI
Kinase CG2309.AA ERK5 25-319 35 1.8e-81 276.98 In-house 1-295 (295) Show / Hide 
Range on Protein: 25-319
Range on HMM: 1-295/295
Sequence Identity: 35% (107 aa)

FDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNL----DFYLVFEFMESDLHNVIKRGNV
...  ..| ||||.|  |  |.. . ||.||.  ||   | |.||.||.  || || | ||. . || .    .    | | ||. |||||| .|     
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFR-HDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQP

LKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRNYTKGIDMWGLG
.   | |. .||..  .|..|| .||||||||||.|.   | ||. |||.|| |.    .   ..   .|.|||||||||||....| .||. ||.|  |
FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCT---FSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVG

CILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYV
||.||||  . .| |   ..|.. |.  |       | ...       . .|.   .   ....       ...|.  .|.  | .|.|. .|..||..
CIFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase CG2309.AA Pkinase 25-319 27 4.5e-79 273.81 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-319
Range on HMM: 1-293/293
Sequence Identity: 27% (86 aa)

FDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYR--EVIFLRAFRCHPNIVRLVDIFKASNNLDFYLVFEFMES-----DLHNVIK-
. . .. |.|..| |.|.... |  .||.|..    ...   |.  |  |.  .. . .||||||| |.|    . . |.|.|..|      ||. .|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

-RGNVL--KDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRL----KVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRN
 |....   . . .|.|||.. .....|| ..|||||||.|||||... .    |..|||||. ..       .  .. .|... |.||.|||..  .. 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEVIRGGQY

YTKGIDMWGLGCILGEMIRQKPLFQGT----STVNQIEKIVTSLPNVTKLDIASI--GPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLN
|.. .|||..|||| ||.  .|.|.|     . ..|...|.  ..  .. |.     .. |  .   .         . .  .|  .......| .| ..
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTF-HNWSEECKDFIKWCLCKD

PHNRLTAKEAIRHPYV
|. |.||...  ||..
PKKRPTAEQILQHPWF
Kinase CG2309.AA p38 25-246 41 2.1e-78 266.8 In-house 1-217 (289) Show / Hide 
Range on Protein: 25-246
Range on HMM: 1-217/289
Sequence Identity: 41% (96 aa)

FDVRKRMGKGAYGIVWKATDRRTKNT---VALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKA-----SNNLDFYLVFEFMESDLHNVIK
.   .  |.|||| | || ||||..    || || .  | .| .| |||||.  |.  | | |.. | |.|       ..  |.|.| .||..||.|..|
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

RGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRNYTKGIDM
    | | | .|  ||.. . |.||| ..|||||||||| .   | |.. ||||||           ..|  .|.||||||||||||.     ||. .|.
CQR-LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR-----------HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDI

WGLGCILGEMIRQKPLFQGTSTVNQIEKIV
| .|||. |.| ...|| |.  ..|...|.
WSVGCIMAELITGRTLFPGDDHIDQLQRIM
Kinase CG2309.AA CDC2 25-245 37 3.6e-72 220.94 In-house 1-221 (301) Show / Hide 
Range on Protein: 25-245
Range on HMM: 1-221/301
Sequence Identity: 37% (87 aa)

FDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQR------TYREVIFLRAFRCHPNIVRLVDIFKASNNLDFYLVFEFMESDLHNVIK--
.   .. |.| ||.| |. |..|.  |||||.    | |..         . ||   | . . |||||.| |...  |.|  |.|||... || .  .  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKI----RLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKL--YMVFEYLDMDLKKYMDMS

--RGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTD-YVATRWYRAPEILVASRNYTKG
   . ..     .  |||..... | |.  ..||||||.|||||.| ..|.|||||||. .          .  .|.  | |.||||||||  .. |. .
IPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFG-------IPIRTYTTEHEVVTLWYRAPEILLGCKRYSTP

IDMWGLGCILGEM---IRQKPLFQGTSTVNQIEKI
.||| .|||. ||   .  ||||.| |   |. ||
VDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKI
Kinase CG2309.AA ERK1 25-319 38 1e-69 237.91 In-house 1-289 (289) Show / Hide 
Range on Protein: 25-319
Range on HMM: 1-289/289
Sequence Identity: 38% (115 aa)

FDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKAS---NNLDFYLVFEFMESDLHNVIKRGNVL
.   . .|.||||.|  | |...|. ||.||.   |   |  ||| ||.  |  |. | ||. . || .|.   .  | |.| . || ||  ..|  .. 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFK-HENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

KDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYD-DLEQDGMLTDYVATRWYRAPEILVASRNYTKGIDMWGLG
 | |  . .||..  .|.||| ||.||||||||.|.   | ||. |||||      || | . .  | ||.||||||||||||.. |. ||| ||.|  |
ND-HICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLA------RIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVG

CILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYV
||| ||.  .|.| |   . |. .|.  |    . |.  |        | . .    . .....  .     . |.  .|  |||.|.|  ||. |||.
CILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYL-QSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase CG2309.AA MAPK-Unclassified 25-172 39 5.8e-53 182.26 In-house 1-157 (575) Show / Hide 
Range on Protein: 25-172
Range on HMM: 1-157/575
Sequence Identity: 39% (62 aa)

FDVRKRMGKGAYGIVWKATDRRT-KNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIF--KASNN---LDFYLVFEFMES---DLHNVI
 .. |  | ||||.| .|.| .. .  || |||  .| ..||. |. ||.  ||    ||||... |||  |   |    | |.| ..|..   ||| .|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYL-NHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQII

KRGN-VLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLAR
|     . . | .  .||. . .| .|| ..|||||||||.||. .| ....|||..|
KSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase CG2309.AA MAPK-Unclassified 181-249 28 1.5e-22 78.02 In-house 397-496 (575) Show / Hide 
Range on Protein: 181-249
Range on HMM: 397-496/575
Sequence Identity: 28% (29 aa)

DDLEQDGMLTDYVATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIR-----------QKPLFQGTS--------------------TVNQIEKIVTSL
.| .  . .| ||.|||||||||.  . .|.. .|.| .|||..||.            ..||| |..                     . ||  |.. |
NDCHHCYHMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYL
Kinase CG2309.AA Pkinase_Tyr 25-174 28 9.3e-13 43.83 Pfam 1-161 (270) Show / Hide 
Range on Protein: 25-174
Range on HMM: 1-161/270
Sequence Identity: 28% (47 aa)

FDVRKRMGKGAYGIVWKATDR----RTKNTVALKKVFDAFRDETD--AQRTYREVIFLRAF-RCHPNIVRLVDIFK-ASN-NLDFYLVFEFMES-DLHNV
    |  |.||.| |.|.| .     || .|| |..     .. .   .   ||.  .. . . |||||||. .    .  |   |.|.|.|.  ||.. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGH-HPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDY

IKR----GNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTL
 ..    .. |.  ..    .|  ..  . .| | |||||   |.|....   |..||||||..
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase CG2309.AA CDC2 281-319 31 1.1e-12 34.74 In-house 254-301 (301) Show / Hide 
Range on Protein: 281-319
Range on HMM: 254-301/301
Sequence Identity: 31% (15 aa)

LDEMMKN---------CCDDGISLVKALLVLNPHNRLTAKEAIRHPYV
| ....|         ....||.| . .|...| .|..||||..||| 
LSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CG2309.AA TyrKc 25-322 20 1.5e-12 -19.79 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-322
Range on HMM: 1-280/280
Sequence Identity: 20% (68 aa)

FDVRKRMGKGAYGIVWKATDRRTKNTVALKKVF-DAFRDETDAQRTYREVIFLRAF-RCHPNIVRLVDIFKAS-----NNLDFYLVFEFMES-DLHNVI-
    |  | ||.|.|.|.| .    .|| |..  ||       .  .||   .. .   |||||||. .   .          ..|.|.|.  ||.. . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KRGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSR------RIYDDLEQDGMLTDYVATRWYRAPEILVASRN
|... |.  ..   ..|  .   ..|| |.|||||   |.|.... . |..||||.| . .         | .  . .   . .  ||. ||| .   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGK

YTKGIDMWGLGCILGEMI----RQKPL-----FQGTSTVNQIEKI-VTSLPNV----TKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGI-S
.|   | |  |  . |.        |         .  ......      |                                         || | . .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------------F-VCCPDEMYQ

LVKALLVLNPHNRLTAKEAIRHPYVSRF
. |     .|..| | .|      ...|
IMKQCWHEDPEDRPTFSEI-----HECF
Kinase CG2309.AA CDK 246-319 17 2.9e-09 25.64 In-house 252-284 (284) Show / Hide 
Range on Protein: 246-319
Range on HMM: 252-284/284
Sequence Identity: 17% (13 aa)

VTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYV
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VTKLPDY-----------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CG2309.AA p38 293-319 48 1.7e-07 21.37 In-house 263-289 (289) Show / Hide 
Range on Protein: 293-319
Range on HMM: 263-289/289
Sequence Identity: 48% (13 aa)

ISLVKALLVLNPHNRLTAKEAIRHPYV
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IDLLEKMLELDPDKRITAEEAMQHPYF
Kinase CG2309.AA ERK 280-319 30 7.1e-07 21.85 In-house 266-307 (307) Show / Hide 
Range on Protein: 280-319
Range on HMM: 266-307/307
Sequence Identity: 30% (13 aa)

SLDEMMKN--CCDDGISLVKALLVLNPHNRLTAKEAIRHPYV
.. .. .|  |  ..| | . .|| .|  |.|..|...||| 
PWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase CG2309.AA MAPK-Unclassified 293-319 44 2.2e-05 14.84 In-house 549-575 (575) Show / Hide 
Range on Protein: 293-319
Range on HMM: 549-575/575
Sequence Identity: 44% (12 aa)

ISLVKALLVLNPHNRLTAKEAIRHPYV
| .|. .|. ||  | || .|  |||.
IDFVQKMLQFNPWKRITADQALEHPYF