Gene nmo (Fruit Fly)

nmo

Species: Fruit Fly
Alias: NEMO, CG7892, Nemo, clone 2.43, SFO180, adirondack, anon-EST:Liang-2.43, nmo, Nlk, adk, NEMO/NLK
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 66A21--B2,

Classification

Group: CMGC
Family: MAPK
Subfamily: nmo

Sequence

Name Sequence Type Origin Length Description Download
nmo.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 290 Kinase domain by global Sugen HMM Fasta, JSON
nmo.AA Protein Various 474 None Fasta, JSON

Protein domain

Protein domains of nmo.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase nmo.AA nmo 40-329 85 2.8e-252 785.24 In-house 1-292 (292) Show / Hide 
Range on Protein: 40-329
Range on HMM: 1-292/292
Sequence Identity: 85% (251 aa)

VQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLS
.|||||||||||||||.|||||||.||||||.|||||.|||.|||||||||||||||.|||||||||||||.||||||||.|||.|||||||||||||||
IQPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVSPQHLS

ADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGR
.||.|||||||||||||||||.|||||||||||||||||||||||||||||.|.||.||||||||||||||||||||||||.||||.|||||||.|||||
SDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGR

RILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSS--HATHEAVHLLCQMLVFDPDKRISVTDALAHPYL
|||||||.|.|||..||.|||||.||||..|||||..||||...|||...|||||||  |||||||||||.||.||||||||..||||||||
RILFQAQSPIQQLQMITDLLGTPSMEDMKYACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase nmo.AA MAPK 40-329 43 2.7e-174 585.32 In-house 1-328 (328) Show / Hide 
Range on Protein: 40-329
Range on HMM: 1-328/328
Sequence Identity: 43% (144 aa)

VQPDRPIGYGAFGVVWAVTDPR------DGRRVALKKLPNVFQSLVSSKRVFRELKMLCFF-KHENVLSALDILQP------PHLDFFQEIYVITELLQS
 |...|||.||.|||....| |      .|..||.||....||.... ||..||.|.|..| .|||. . |||..|      ..|. |..||...|| ..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLHKIIVSPQHLSADHIKVFLYQILRG--LKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQA-------------KHMTQEVVTQYYRAP
|||.|| |.|.|| |||. |.||||||  |||.|||...|||.||.|.|||.|| ||||||||||...|..              .|||. |.|..||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EILMG--ARHYSSAVDVWSVGCIFGELLG-RRILFQAQNPVQQLELITELLGTPTMEDMRHAC-EGARTHMLRR----APKPP-SFSVLYTLSS-HATHE
||...  ..||. |||.|||||||.|.|. |..||. .... |..||.|.||||..|...  |   .  .....     ..|. ... ..  .. .|...
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

AVHLLCQMLVFDPDKRISVTDALAHPYL
|..||..||||||||||.| .||.|||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase nmo.AA ERK 45-329 43 2.5e-125 422.66 In-house 6-307 (307) Show / Hide 
Range on Protein: 45-329
Range on HMM: 6-307/307
Sequence Identity: 43% (133 aa)

PIGYGAFGVVWAVTDPR-----DGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFK-HENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHL
.||.||.||| ...|       .| .|| || .|.|  ..  ||  ||.|.| .|| |||. . .||. |   . . .||...|| ..|||.|| |.| |
QIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIINSQQEL

SADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAK-------HMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGC
| ||.. |.||||.||||.||| ..|||.||.|.||||||.||||||||||........       .||. |.| .||||||.  .. |..|.|.||.||
SDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGC

IFGELLGRRILFQAQNPVQQLELITELLGTP-TMEDMRHACEGARTHMLRRAPK----PPSFSVLYTLSSHAT--HEAVHLLCQMLVFDPDKRISVTDAL
|| |.|||. ||.  . | |...|....||| . ||..  |      ...  |.    | ... ..   . |   ..|. || .||||||||||.| ..|
IFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIF---PNANCNPQAIDLLEKMLVFDPDKRITVEECL

AHPYL
.|||.
EHPYF
Kinase nmo.AA CMGC 40-329 24 3e-121 400.48 In-house 1-513 (513) Show / Hide 
Range on Protein: 40-329
Range on HMM: 1-513/513
Sequence Identity: 24% (125 aa)

VQPDRPIGYGAFGVVWAVTDPRDGRR--------------VALKKLPNVFQSLVSSK----------RVFRELKMLCFFK-----------------HEN
 . ...|| |..|||.  .| | ...              ||.||. |.|      |          | .||.|.|  ..                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VLSALDILQPPH-------------LDFFQEIYVITELLQSDLHKIIVSPQ---------HLSADH------------IKVFL------YQILRGLK--Y
... .||.....             .  |...| ..|... ||...| . |         .||  |            || |.      ||||||||  |
IVKLYDIFYHKNSDGNEYEDKHIISQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

LHSAR--ILHRDIKPGNLLVNSNCVL--------------------KICDFGLARVEEPDQ--------------------AKHMTQEVVTQYYRAPEIL
.||..  |.|||.|| |.|.|.|| |                    ||||||||| ..| .                     ...|..||| .|||||||
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

MGARHYS---------SAVDVWSVGCIFGELLGR--------RILFQ-----------AQNPVQQLELITELLGTP----------------TMEDMR--
.|..||.         ...|.|||||||.|.. .        ..||.            .. . ||..| ..||||                . |..   
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

-------------------HACEGARTHMLR----RAPKPPSFSVLYTLSSH--------------------------------ATHEAVHLLCQMLVFD
                   | .|.||..  .      ..|.... |.  ..                                 ....|..||..||..|
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PDKRISVTDALAHPYL
|||||.. .||.|||.
PDKRITAEQALQHPYF
Kinase nmo.AA p38 40-329 42 2.7e-108 366.07 In-house 1-289 (289) Show / Hide 
Range on Protein: 40-329
Range on HMM: 1-289/289
Sequence Identity: 42% (127 aa)

VQPDRPIGYGAFGVVWAVTDPRDGRR---VALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQP--PHLDFFQEIYVITELLQSDLHKIIVS
 |  .|.| ||.| | .. | | | .   || |||   ||| .  || .|||. |   .||||...||.  |    .. ||..|..|.. ..||..|. .
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

PQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFG
 |.|| |||.  .||||||||| ||| | ||| ||.|. || .| |.| ||||||     ... ||. |.|  ||||||.    ||  .||.||||||  
-QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR----HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMA

ELLGRRILFQAQNPVQQLELITELLGTPTMEDMRH-ACEGARTHMLRRAPKP-PSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYL
||. .|.||  .....||. |....|||. | .   . | ||. .  ... |   |. ...    |.  |. ||  ||. ||||||.. .|..|||.
ELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFM---GANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase nmo.AA ERK5 41-329 43 1e-104 354.22 In-house 2-295 (295) Show / Hide 
Range on Protein: 41-329
Range on HMM: 2-295/295
Sequence Identity: 43% (129 aa)

QPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPH-LDFFQEIYVITELLQSDLHKIIVSPQHLS
..   || ||.||| .    . |..||.||.|| |  .   || |||||.|  |.|.|..   |||.|   .  ....||. .|. ||||.|| | | ..
KIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPFT

ADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEP-DQAKH---MTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGE
 .||. |||||||||||.||| ..|||.|| ||||| || ||| |||.||       .||   ||. | | .|||||...    |  |.|||||||||||
LEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIFGE

LLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRR--APKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYL
...|| .|  .|...||.|| . ||.|    ..          . .  ... |    . ..   |   |. || .||.|.| .||.|  || ||.|
MIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQP--KDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase nmo.AA S_TKc 40-329 26 3.9e-89 303.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 40-329
Range on HMM: 1-231/231
Sequence Identity: 26% (80 aa)

VQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQS---DLHKIIVSPQ
 .  |.|| ||||.|. ... ..||.||.|...         ... ||...|   .|.|.   .|. |       ...|...|..     ||...|.. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRG

H------LSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSS-AVDVWSV
.      ..  |.. ..|||...|.|.|| .|.|||.|| |.|...  ..|||||||||.         |  ..| .|.|||.|    .|.  ..|.||.
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALA----
|||. |.| .. .|.      |.... ...|                                      ..|| ......|..||.||... .||.    
GCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD

---HPYL
   ||..
IKCHPWF
Kinase nmo.AA ERK7 39-329 36 7.8e-89 301.44 In-house 2-292 (292) Show / Hide 
Range on Protein: 39-329
Range on HMM: 2-292/292
Sequence Identity: 36% (108 aa)

DVQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFK-HENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQH
...  . .| ||.|.|| ..| | .  |||||    |.  . . | |||  .|  |. |.|... .....    |  . ||.. | . .||| .|   . 
EIR--KRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIR---ADNDRDIYLVFEFMETDLHAVIRKGNI

LSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLAR----VEE-PDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCI
|   | .. .||.|| .||.||....|||.|| |.|..|.|..|.|||||||     ||  .|   .|  | |  |||||||.|...|  .|| ||.|||
LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCI

FGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYL
 ||.|  . .|.    . |.|.| |... ||.||.       .  || . .       |  .  .. ..|. || ..||| |.||.....||.||| 
LGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN-QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase nmo.AA ERK1 44-329 43 1.3e-88 300.71 In-house 5-289 (289) Show / Hide 
Range on Protein: 44-329
Range on HMM: 5-289/289
Sequence Identity: 43% (125 aa)

RPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHI
. || ||.|.| .  | . ..|||.||.   |      .|  ||.|.|  |||||..   ||.. . .. ....|.. .|.  || |.. . |||| |||
QYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKT-QHLSNDHI

KVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEP--DQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRI
  |||||||||||.||| .||||.|| |||.|  | ||||||||||. .|  |    .|  | | .||||||.. .. |  ..|.||||||  |.|  | 
CYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP

LFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYL
.|  .  . || .|  .|| |  .|..          |.  |  |  . .  |  .|   |. || .|| | |.||| | .|||||||
IFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVP-WARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase nmo.AA JNK 41-329 37 1.3e-82 280.8 In-house 2-309 (309) Show / Hide 
Range on Protein: 41-329
Range on HMM: 2-309/309
Sequence Identity: 37% (116 aa)

QPDRPIGYGAFGVVWAVTDPRDGRRVALKKL--PNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPH-LDFFQEIYVITELLQSDLHKIIVS-PQ
| ...|| || |.| .  |   ..||| ||.  |. ||   . || .||.. .   .|.|. . . .  |   |. ||..|.. |.    |. .| | . 
QNLKFIGQGAQGIVCMAFDQVTNQRVAIKKMMRPDNFQNWMHWKRAYREFICMKCINHKNIIKMYNCFTPQETLEEFQDVYIVMEYMDWNLCQVIHSTFM

HLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGAR-HYSSAVDVWSVGCIFGE
 |  . .. ..||...| |.|||..| ||| || | .||. |.|||||||.|| | |.    ||  ||| ||||||.. |    |.  ||.||||||..|
ELDHERMSYLFYQMCCGIKHLHSMGIIHRDLKPSNIVVNQDCTLKICDFGHARTEDPT--FMMTPYVVTRYYRAPEVICGMMDNYKENVDIWSVGCIMAE

LLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRR----APKPPSFSVL------Y-TLSSHAT-----HEAVHLLCQMLVFDPDKRIS
..  ..||. .    |  .| |.||||. . |    . .|. ...|      .| .|. .      . ...|        | |  ||  ||| .||.|||
MIRHHVLFPGKDHIDQWNKIIEFLGTPDPHFMMQMQPHVRNYVENRNMDPYYQPYNFHEHFPDTLFPDVMQSEPKDHLTCHMARDLLFRMLVINPDDRIS

VTDALAHPYL
| ||| |||.
VDDALQHPYI
Kinase nmo.AA Pkinase 40-329 28 5.4e-82 283.5 Pfam 1-293 (293) Show / Hide 
Range on Protein: 40-329
Range on HMM: 1-293/293
Sequence Identity: 28% (89 aa)

VQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFR--ELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQS-----DLHKII
 .  |.|| |.||.|.  ..  .|..||.|... . ..    .. .|  |....  ..|.|..  .|. .       ..||...|...      ||. .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

V--SPQHL--SADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVL----KICDFGLARV--EEPDQAKHMTQEVVTQYYRAPEILMGARHYSS
   .   .  | ...| ..|||||||.|.|| .|.|||.|| |.|...|...    ||||||||..  . ...   ||  ..| .|.|||...|...|..
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS---MTTFCGTPWYMAPEVIRGGQYYGP

AVDVWSVGCIFGELLGRRILFQAQ----NPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRI
.||.||.|||. |.| .| .|. .    | . |...| . .|.|...|    |.. . . .|. . .     . |.   .. |. .... .| .|| ||.
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---F-HWTF-HNWSEECKDFIKWCLCKDPKKRP

SVTDALAHPYL
. ...| ||..
TAEQILQHPWF
Kinase nmo.AA MAPK-Unclassified 41-192 43 2.9e-62 213.15 In-house 2-161 (575) Show / Hide 
Range on Protein: 41-192
Range on HMM: 2-161/575
Sequence Identity: 43% (69 aa)

QPDRPIGYGAFGVVWAVTDPRD-GRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPHLDF--FQEIYVITELLQS---DLHKIIVS
 ..  || ||.|.|   .| .  .. || ||.. .|.  .  ||| ||.  |    |.|..   ||. .  |    |. ||. ... |.   |||.|| |
EYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIKS

PQ-HLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLAR-VEE
.| |..  ||. |.||||||||||||| |.||| || |||.| .| ..|||||..| .|.
NQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSIED
Kinase nmo.AA MAPK-Unclassified 198-329 30 9.7e-37 128.38 In-house 404-575 (575) Show / Hide 
Range on Protein: 198-329
Range on HMM: 404-575/575
Sequence Identity: 30% (53 aa)

HMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGR-----------RILFQAQN--------------------PVQQLELITELLGTPTMED
|||| ||| .||||||..    |. .|| ||.||||.|.. .           |.|| .|.                     . |. .| . ||.|  ||
HMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEED

MRH-ACEGARTHMLRRAPKPP-SFS-VLYTLSS------HATHEAVHLLCQMLVFDPDKRISVTDALAHPYL
..   |  ||      ..|.|  |.   .   .          |.  .. .||.|.| |||.  .|| ||| 
CNFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase nmo.AA Pkinase_Tyr 40-228 26 8.8e-17 57.46 Pfam 1-199 (270) Show / Hide 
Range on Protein: 40-228
Range on HMM: 1-199/270
Sequence Identity: 26% (54 aa)

VQPDRPIGYGAFGVVW---AV-TDPRDGRRVALKKLPNVFQSLV-SSKRVFRELKMLCFF-KHENVLSALDILQ---PPHLDFFQEIYVITELLQS-DLH
.. .. .| ||||.|.   .   .  ..  || |.|..   .    ..  .||.|... . .|.|... . .      |      .||...|. .  ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-----QIYIVMEYMPHGDLL

KIIVS----PQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVE-EPDQA-KHMTQEVVTQYYRAPEILMGARHYSSA
.   .    .|.|.  ..  . .|| .|. ||.| .. |||.   | ||..| | |||||||||   . |.  .  .   .     ||| ..  . ....
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTK

VDVWS
 ||||
SDVWS
Kinase nmo.AA TyrKc 40-329 19 1.7e-14 11.64 SMART 1-280 (280) Show / Hide 
Range on Protein: 40-329
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

VQPDRPIGYGAFGVVW-AVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFF--KHENVLSALDILQPP--HLDFF---QEIYVITELLQS-DLHK
.. .. .| ||||.|. .. .    . || |.| .        .   ||....| .  .|.|..  . .   .      |   . .....|.    ||..
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN---FMYIEPLMIVMEYMPHGDLKD

IIVSPQH-LSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPD-------QAKHM-----TQEVVTQYYRAPEILMGA
 . .... |. ..   | .|| .|  |||| .. |||.   | ||..| . ||.||||.|  . |       . ...     .  ..     ||| .   
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NY

RHYSSAVDVWSVGCI------FGELLGRRILFQAQNPVQQLELITELLGTPTMED---MRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQ
. .... |||| |        .|.     . .|  .. . .|.. .    | ...   |                           . ... |   .  |
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------FVCCPDEMYQIMKQ

MLVFDPDKRISVTDALAHPYL
   .||..| . ..   | ..
CWHEDPEDRPTFSEI--HECF