Gene ERK7 (Mouse)

ERK7

Species: Mouse
Alias: ERK7
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
Erk7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 292 Kinase domain by global Sugen HMM Fasta, JSON
Erk7.NA RNA Sugen 1930 None Fasta, JSON
Erk7.AA Protein Sugen 549 None Fasta, JSON

Protein domain

Protein domains of Erk7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Erk7.AA ERK7 14-305 66 1.2e-211 709.41 In-house 1-292 (292) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-292/292
Sequence Identity: 66% (195 aa)

YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLLDVIPAKNDRDIYLVFESMDTDLNAVIQKGRLLKDI
|.|..|||||||||||||.|.||..|||.||||||||.|.||||||||||.|.||..|||||||..||.|.||||||||||.|.|||.|||.||..||||
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDI

HKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGDLPE-GPGGQALTEYVATRWYRAPEVLLSSRWYTPGVDMWSLGCILGEM
||..|.||||||.|..|||.|||||.||.|.||||.|.||.||||||||.....| ..  ..||||||||||||||.||.|..||.||||||.|||||||
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEM

LRGQPLFPGTSTFHQLELILKTIPLPSMEELQDLGSDYSALILQNLGSRPQQTLDALLPPDTPPEALDLLKRLLAFAPDKRLSAEQALQHPYV
|||.|.||||||..|.|.||.||| |..|.....||.|.. .|.........|||...| .....|.|||||||.|.|.|||.||||||||||
LRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMP-QCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase Erk7.AA MAPK 14-305 42 6.2e-171 574.16 In-house 1-328 (328) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-328/328
Sequence Identity: 42% (138 aa)

YLIKRRLGKGAYGIVWKAMDRR------TGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLLDVIPAK-----ND----RDIYLVFESMDT
| | ...|.||||.|..|.|.|      .|. ||||||...|.......||.|||.||..|..|.|||.|||.. ..     |.    .|||.|.| |.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLNAVIQKGRLLKDIHKRCIFYQLLRA--TKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGDLPEGPGGQ---------ALTEYVATRWYRAP
||...|. .. | |.|.. ..||.||.   |.|||..||||| ||.|.|... | .|.||||||||. .  . ...|          .||||||||||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EVLLS--SRWYTPGVDMWSLGCILGEMLR-GQPLFPGTSTFHQLELILKTIPLPSMEELQDLG-SDYSALILQNL---GSRPQQTLDALLPP---DTPPE
|..|.  .. || .|||||.|||..|||. ..|||||... .|..||..... ||.| .| .. |.  .  .|.|     .|..... ..|    .. |.
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

ALDLLKRLLAFAPDKRLSAEQALQHPYV
|.|||...|.| ||||...|.||||||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase Erk7.AA CMGC 14-305 25 3.8e-134 443.64 In-house 1-513 (513) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-513/513
Sequence Identity: 25% (130 aa)

YLIKRRLGKGAYGIVWKAMD--------------RRTGEVVAIKKIFDAFRDQIDAQ----------RTFREIMLLKEFG----------------GHPN
| | ...|.|.||.|.|. |              ..|.|.||||||. .| ....|.          |..|||..||..                  |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIRLLDVIPAKN---------------DRDIYLVFESMDTDLNAVIQKGR---------LLKDIH------------KRCIF------YQLLRATK--FI
|..|.|..  ||               ....||||| ||.||  .|.. .          |.. |            .....      ||.||. |  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSGR--VIHRDQKPANVLLDSACRV--------------------KLCDFGLARSLGDLPEGPG----------------GQALTEYVATRWYRAPEVLL
|| .  .|||| ||.|.|... |..                    |.|||||||.... .. ..                ....|.||.||||||||.||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

SS---------RWYTPGVDMWSLGCILGEMLRG--------QPLFP-----------GTSTFHQLELILKTIPLP----------------SMEELQDLG
..         . ||...||||.|||..||..|        .||||           |.|. .||..| |..  |                . |  . ..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

--------------------SDYSALILQN---LGSRPQQTLDALLPP----------------------------------DTPPEALDLLKRLLAFAP
                    |.   . .|.   .. .| ...  | |.                                  . .|.|.||||..| . |
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

DKRLSAEQALQHPYV
|||..||||||||| 
DKRITAEQALQHPYF
Kinase Erk7.AA ERK 14-305 44 2.1e-113 383.02 In-house 1-307 (307) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-307/307
Sequence Identity: 44% (139 aa)

YLIKRRLGKGAYGIVWKAMDRR-----TGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLLDVIPAK---NDRDIYLVFESMDTDLNAVIQ
| |  ..|.||||.| .| |       ||. ||||||..|| . |.. || ||| ||. | ||.||| |.|..  .   .  |||.|.| |.|||  .|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

KGRLLKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLAR----SLGDLPEGPGG--QALTEYVATRWYRAPEVLLSSRWYTPG
    | | |     ||.|.. |.|||  ||||| || |.|. | |  | |||||||    |  . .|   .  . .|||||||||||||..|| . ||  
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHE---CNQNFMTEYVATRWYRAPEIMLSWQKYTKA

VDMWSLGCILGEMLRGQPLFPGTSTFHQLELILKTIPLP-SMEELQDLGSDYSALILQNLGS--RPQQTLDALLPPDTP--PEALDLLKRLLAFAPDKRL
.|.|| |||. |||...||||| .. ||...|...|  | | |.||. .|.     . ||.   || . .  .  |...  |.|.|||...|.| ||||.
MDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIF-PNANCNPQAIDLLEKMLVFDPDKRI

SAEQALQHPYV
..|..|.||| 
TVEECLEHPYF
Kinase Erk7.AA CDK 14-305 34 2e-99 318.8 In-house 1-284 (284) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-284/284
Sequence Identity: 34% (113 aa)

YLIKRRLGKGAYGIVWKAMDRRTG-----EVVAIKKIFDAF-----RDQIDAQRTFREIMLLKEFGGHPNIIRLLDVIPAKN---------DRDIYLVFE
| .  ..| |.||.| || |..||     ..||.|||          .    . . ||| ||||   ||||..|.||.. ||         .. .|.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

SMDTDLNAVIQKGRLLKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACR-----VKLCDFGLARSLGD-LPEGPG-GQALTEYVATRWYRAP
 ||.||  ..           .|...||||.  ..|| ...||| ||.| |...        .|. ||||||  |  .... .  ...|  | |.|||||
YMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYRAP

EVLLSSRWYT--PGVDMWSLGCILGEMLR---GQPLFPGTSTFHQLELILKTI------PLPSMEELQDLGSDYSALILQNLGSRPQQTLDALLPPDTPP
|.|| |. |.  ...||||.|||..||..   ..|||||.|  .||..| ...        |....|.|                               
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------------

EALDLLKRLLAFAPDKRLSAEQALQHPYV
   ||| ..|.. |.||.|||||||||| 
---DLLNKMLCYDPKKRISAEQALQHPYF
Kinase Erk7.AA S_TKc 14-305 33 4.3e-99 336.42 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-231/231
Sequence Identity: 33% (104 aa)

YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLLDVIPAKNDRDIYLVFESMDT---DLNAVIQKGRL-
| | | .||||.| |.|. ...||..||||.|          ... ||| .||.  .||||..|.||.      ..|.|.| .|.   ||  .|.| .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGDLPEGPGGQALTEYVATRWYRAPEVLLSSRWYTP-GVDMW
     .   | |...||...| ...|| ..|||| ||.|.|||.  ..|.||||||| |            | .. |.||.|||||     |..  .|.|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL----GYGKCKCDWW

SLGCILGEMLRGQPLFPGTSTFHQLELILKTIPLPSMEELQDLGSDYSALILQNLGSRPQQTLDALLPPDTPPEALDLLKRLLAFAPDKRLSAEQALQ--
|.|||| ||| |.|.||      |.....| |                                       .|||.|.....| . |.||..| .|||  
SCGCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDE

-----HPYV
     ||..
WDIKCHPWF
Kinase Erk7.AA p38 14-305 41 1.6e-96 326.96 In-house 1-289 (289) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-289/289
Sequence Identity: 41% (124 aa)

YLIKRRLGKGAYGIVWKAMDRRTGEV---VAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLLDV-IP----AKNDRDIYLVFESMDTDLNAVIQ
|   . .|.|||| | ||.|||||.    |||||..  | . |.| ||.||. |||    | |.| ||||  |    ... .|.|.| . |..||| .. 
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHM-RHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

KGRLLKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGDLPEGPGGQALTEYVATRWYRAPEVLLSSRWYTPGVDMWSL
  | | | | . . ||.||. |.|||  .|||| || |. .   | ..  ||||||        .  . .|.|||||||||||..|.   ||  ||.||.
CQR-LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR--------HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSV

GCILGEMLRGQPLFPGTSTFHQLELILKTIPLPSMEELQDLGSDYSALILQNLGSRPQQTLDALLPPDTPPEALDLLKRLLAFAPDKRLSAEQALQHPYV
|||. |.. |..||||.   .||. |.| .  |. | .| . |. .   .|..  .|.. .  ...  .| . .||| ..|   ||||..||.|.|||| 
GCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQA-IDLLEKMLELDPDKRITAEEAMQHPYF
Kinase Erk7.AA Pkinase 14-305 32 1.1e-89 309.04 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-293/293
Sequence Identity: 32% (100 aa)

YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFR--EIMLLKEFGGHPNIIRLLDVIPAKNDRDIYLVFESMDT-----DLNAVIQ-
| |.|..|.|..| |.|.... ||..||.|.|    ..    |. .|  || ..|.. .||||.||.|.     ...||.|.| ..      || ..|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

-KGRLL--KDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRV----KLCDFGLARSLGDLPEGPGGQALTEYVATRWYRAPEVLLSSRWYTP
 ... .   . . ....||.||. ...|| ..|||| ||.|.|.|. . .    |.||||||. .        .. .| .. |.||.||||..... |.|
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

GVDMWSLGCILGEMLRGQPLFPGT----STFHQLELILKTIPLPSMEELQDLGSDYSALILQNLGSRPQQTLDALLPPDTPPEALDLLKRLLAFAPDKRL
 |||||.|||| ||| |.|.|||     .   |...| .. . | ... . . | .    ..    .   .   .. . ...|..|..|..|.. | ||.
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---F-HWTF-HNWSEECKDFIKWCLCKDPKKRP

SAEQALQHPYV
.|||.||||..
TAEQILQHPWF
Kinase Erk7.AA ERK5 14-305 41 1.2e-89 304.19 In-house 1-295 (295) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-295/295
Sequence Identity: 41% (122 aa)

YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLLDVI----PAKNDRDIYLVFESMDTDLNAVIQKGRL
| |  ..| ||||.|  |. |..|. ||||||  ||     |.|||||. .|. |  | ||| . |..    |    .|.| ||. |. ||  .|     
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHF-RHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQP

LKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGDLPEGPGGQALTEYVATRWYRAPEVLLSSRWYTPGVDMWSLGCIL
.   | |   ||.||  |..||  ||||| ||.|.|    | .|. |||.|| |  .        .|||||||||||||...||  ||  .|.|| |||.
FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIF

GEMLRGQPLFPGTSTFHQLELILKTIPLPSMEELQDLGSDYSALILQN-LGSRPQQTLDALLPPDTPPEALDLLKRLLAFAPDKRLSAEQALQHPYV
|||.  . .|||    |||.||.. . .|.   .|  ..|     .|  .  |  . .. .  |   . ||||| |.| | | .|... .|||||..
GEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVY-PKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase Erk7.AA ERK1 14-305 45 1.6e-87 297.08 In-house 1-289 (289) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-289/289
Sequence Identity: 45% (133 aa)

YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLLDVIPAK---NDRDIYLVFESMDTDLNAVIQKGRLL
|.  . .|.||||.|  |.|..... ||||||   |  |   ||| ||| .|. |  | ||| . |.| |.   . ||.|.| . |.|||  ...  .| 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRF-KHENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

KDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGDLPEGPGGQALTEYVATRWYRAPEVLLSSRWYTPGVDMWSLGCILG
 | |     ||.||  |.|||  |.||| ||.|.||   | .|.||||||| . | ||      ||||||||||||||..| |. ||  .|.|| |||| 
ND-HICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-IAD-PEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILA

EMLRGQPLFPGTSTFHQLELILKTIPLPSMEELQDLGSDYSALILQNLGSRPQQTLDALLPPDTPPEALDLLKRLLAFAPDKRLSAEQALQHPYV
|||   |.|||     || .||  .  || ..|. .  .     || | ..|.. .. |  |.. . ||||| ..|.| |.||.  |.|| |||.
EMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLF-PKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase Erk7.AA CDC2 14-223 40 2e-70 215.52 In-house 1-213 (301) Show / Hide 
Range on Protein: 14-223
Range on HMM: 1-213/301
Sequence Identity: 40% (89 aa)

YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQID--AQRTFREIMLLKEFGGHPNIIRLLDVIPAKNDRDIYLVFESMDTDLNAVIQ----KG
|   ...|.| ||.| |. |..|...||.|||     | .|   . . ||| .|||   ||||..| |||     . .|.||| .| ||         |.
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

RLLKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGDLPEGPGGQALTE-YVATRWYRAPEVLLSSRWYTPGVDMWSLG
  .  .  . ..||.|..  | |. |..||| || | |.|.. ..|. ||||||  |     |  . .||  | |.||||||.|| .. |. .|||||.|
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFG----IPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIG

CILGEM---LRGQPLFPGTS
||. ||       |||.| |
CIFAEMFMDVTKKPLFHGDS
Kinase Erk7.AA MAPK-Unclassified 14-165 38 1.5e-53 184.25 In-house 1-161 (575) Show / Hide 
Range on Protein: 14-165
Range on HMM: 1-161/575
Sequence Identity: 38% (63 aa)

YLIKRRLGKGAYGIVWKAMDRRT-GEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLLDVIPAKNDRD-----IYLVFESMDT---DLNAVI
|. .  .| ||||.| .||| .. .  |||||.  .| ...|. |. ||| .| .   |||||.. |.. .| .       ||.| . | |   ||  .|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYL-NHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQII

QKGR-LLKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGD
.     . ..| . .|||.||  | .||  .|||| ||.|.|..  | |. ||||..||  |
KSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSIED
Kinase Erk7.AA MAPK-Unclassified 175-305 29 4.6e-42 146.05 In-house 405-575 (575) Show / Hide 
Range on Protein: 175-305
Range on HMM: 405-575/575
Sequence Identity: 29% (50 aa)

LTEYVATRWYRAPEVLLSSRWYTPGVDMWSLGCILGEMLRG-----------QPLFPGTS--------------------TFHQLELILKTIPLPSMEEL
.|.||.|||||||| .||.  |.  ||.||.|||..||.             .|||||..                       |. .|.     |  | .
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC

QDLGSDYSALILQNLGSRPQQTLDALLPPDTP---------PEALDLLKRLLAFAPDKRLSAEQALQHPYV
.  ..|     .| ..  ..   . | .. .|         .|..|... .|.| | || .|.|||.|||.
NFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase Erk7.AA TyrKc 14-308 21 1.3e-15 29.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-308
Range on HMM: 1-280/280
Sequence Identity: 21% (71 aa)

YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIF-DAFRDQIDAQRTFREIMLLKEFG-GHPNIIRLLDVIPAK-----NDRDIYLVFESMDT-DLNAVIQ
   .. || ||.|.|.|.. .   . ||.|..  ||       .   ||. .....|  ||||.||. |.  .      .  ...|.| |.  ||.  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KGRL-LKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGDL-------PEGPGGQ--ALTEYVATRWYRAPEVLLSSRW
| |  |.  ..  . .|  .   ..|| ..||||    |.|...  .|| .||||.| ..|              .       .  ||. |||..   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGK

YTPGVDMWSLGCILGEML-RGQPLFPG-----TSTFHQLELILKTIPLPSMEE----LQDLGSDYSALILQNLGSRPQQTLDALLPPDTPPEALDLLKRL
.|.  | || |  . |.. .||.  ||      | .. .|.. .   .| ...                                 .  |.|  .. |. 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------F-VCCPDEMYQIMKQC

LAFAPDKRLSAEQALQHPYVQRF
 .. |..| . ..      ...|
WHEDPEDRPTFSEI-----HECF
Kinase Erk7.AA Pkinase_Tyr 14-206 27 5.5e-15 51.37 Pfam 1-201 (270) Show / Hide 
Range on Protein: 14-206
Range on HMM: 1-201/270
Sequence Identity: 27% (57 aa)

YLIKRRLGKGAYGIVWKAMDR----RTGEVVAIKKIFDAFRDQID--AQRTFREIMLLKEFGGHPNIIRLLDVIPAKNDR-DIYLVFESMDT-DLNAVIQ
  . . ||.||.| |.|.  .     |.  ||.|..     .. .   .  .||. ..|..| ||||.||. |.  . .   ||.|.| |   ||    .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----GRLLKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLARSLGDLPEGPG-GQALTEYVATRWYRAPEVLLSSRWYTPGV
|    .. |.  .. .. .|  ..  . .| . ||||    |.|...   || ||||||| .   ...    ..    .  .|. |||..  .. .|   
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWM-APECINYGK-FTTKS

DMWSLG
| || |
DVWSFG
Kinase Erk7.AA CDC2 262-305 38 6.9e-14 38.55 In-house 250-301 (301) Show / Hide 
Range on Protein: 262-305
Range on HMM: 250-301/301
Sequence Identity: 38% (20 aa)

PQQTLDALLPP--------DTPPEALDLLKRLLAFAPDKRLSAEQALQHPYV
..| |  ..|          ..||..|||...|.  | ||.||..|||||| 
KPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF