Gene p70S6Kb (Mouse)

p70S6Kb

Species: Mouse
Alias: p70S6Kb, Rps6kb2
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSKp70

Sequence

Name Sequence Type Origin Length Description Download
p70S6Kb.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 262 Kinase domain by global Sugen HMM Fasta, JSON
p70S6Kb.AA Protein Sugen 485 None Fasta, JSON
p70S6Kb.NA RNA Sugen 1854 None Fasta, JSON

Protein domain

Protein domains of p70S6Kb.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase p70S6Kb.AA p70 67-328 70 1.3e-216 725.85 In-house 1-299 (299) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-299/299
Sequence Identity: 70% (210 aa)

FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTR-------------------------AERNILESVKHPFIVELAYAFQTG
|||| ||||||||||||||||.|.. |||||||||||||||...|||||||                         |||||||.||||||..|.|||||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

GKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAI----------THTFCG
||||||||.|.|||||.||||.||..||||||||.||..||.|||.||||||||||||.||..|||..||||||||||||.||.          ||||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TIEYMAPEILVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGK--LVLPPYLTPDARDLAKKFLKRNPTQRIGGGLGDAADVQRHPFF
||||||||||.|.|||.||||||||.||||||||.||||.||||||.|||.|||  | ||||||...||| ||.|||.||||.|.|..||||.|.||||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase p70S6Kb.AA AGC 67-328 36 9.5e-191 498.7 In-house 1-395 (395) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-395/395
Sequence Identity: 36% (147 aa)

FELLSVLGKGGYGKVFQVRKVQGT---NLGKIYAMKVLRKAK-IVCSAK-DTAHTRAE------------RNILESVK----------HPFIVE-LAYAF
||.| |.|||..|||..|||. |.     ||.||||||.|.. ||.  | . .|| .|            ||||| ..          |||||  | |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTGGK--LYLILE----CLS-----GG-ELFTHLE---REGIFLEDTACFYLAE-------ITLALGHLHS-HGIIYRD-LKPENIMLSSQGHIKLTDFG
|.  .  ||...|     ..     || |||.||    .||.| |..|.||.||       |.||| .||| .|||.|| ||||||.| ..|||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKESIHEG--------------------------------------------------AITHTFCG--TIEYMAPEILVRTGHNRAVDWWS--LGALMY
|||| . .|                                                  . |.||||  | ||||||||    ...|.||||  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

DMLTGSPPFTAEN----------RKKTMDKII------KGKLVLP----------PYLTPDARDLAKKFLKRNPTQRIGGGLGD-----AADVQRHPFF
 |||| |||...|          ......||.      . |. .|          ....|.|.|| ||.|...|..|.| | .|     | ....||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase p70S6Kb.AA RSK 70-328 57 1.2e-172 579.9 In-house 1-278 (278) Show / Hide 
Range on Protein: 70-328
Range on HMM: 1-278/278
Sequence Identity: 57% (160 aa)

LSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESVK-HPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGI---
|.|||.|||||||..||... . |.|||||||.||||| ..|||.||..|||||| .. |||||.| |||||.||||||.|...||||||||..|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FLEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSS---QGHIKLTDFGLCKE-SIHEGAITHTFCGTIEYMAPEILV----RTGHNRAVDWWSLGA
| ||.||||.|||.||. |||..|||.||||||||.. .   .|||||||||.||. .....  |.|||.||||||||.|     . ||..|.||||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMYDMLTGSPPFTA---ENRKKTMDKIIKGK--LVLP--PYLTPDARDLAKKFLKRNPTQRIGGGLGDAADVQRHPFF
|||.|||| |||..   .|||..|..| |||  | .|  .||...|.|| .| |.|.| .|.|.| .||.....||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase p70S6Kb.AA SGK 67-328 47 7.29999999999e-150 466.29 In-house 1-283 (283) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-283/283
Sequence Identity: 47% (135 aa)

FELLSVLGKGGYGKVFQVRKVQG---------------TNLGKIYAMKVLRKAKIV------CSAKDTAHTRAER-NILESVKHPFIVELAYAFQTGGKL
|..|.|.|||..|||.||....                   .|.||||||.|. |.         |   |. ||| .||  .|||||| | |||||  ||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEILVRT
|. .. . |||.| || ||..|.|| | || ||| .||..|||  |||||||||||.| .|||..||||||||| | .   | ||||| ||.|||.|   
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLAKKFLKRNPTQRIGGGLGDAADVQRHPFF
.| |.||||.||...|.|..| |||   |..   |.||...| .||. ..||.|| .  |...|..| |    |......||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKR-DFMEIKNHPFF
Kinase p70S6Kb.AA Akt 67-328 50 1.3e-145 468.48 In-house 1-264 (264) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-264/264
Sequence Identity: 50% (136 aa)

FELLSVLGKGGYGKVFQVRKVQGTNLGKIY-AMKVLRKAKIVCSAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGI
|..| ||||| .||||.|.| .    .|.| |||||.| .|.      .|| .|||||. ..||||| | |.|||  |||....  .|||||.|| |...
FDFLKVLGKGSFGKVFLVKKKDT---QKWYYAMKVLKKDYIIQKN-QVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR

FLEDTACFYLAEITLALGHLHSHGIIYRD-LKPENIMLSSQGHIKLTDFGLCKES-IHEGAITHTFCGTIEYMAPEILVRTGHNRAVDWWS-LGALMYDM
| ||.| || ||| ||..||||..||||| ||||||.....|||.|||||||||  | .. .| ||||| ||.|||||  .|| .|||||. ||..|| |
FSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEM

LTGSPPFTAENRKKTMDKIIKGKLVLP--PYLTPDARDLAKKFLKRNPTQRIGGGLGDAADVQRHPFF
..| ||| ...... ..||  ...  |  ... |...|| .. |...|..| ||| .|| ...|||.|
MCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase p70S6Kb.AA RSK 67-328 41 1.7e-131 443.17 In-house 1-271 (271) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-271/271
Sequence Identity: 41% (112 aa)

FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIF
.||....|.| ..||. ..|.|.   .. ||||...||... . .    . .||.||. . ||||| |.|.||..||.|.|.. . ||.||..| ... |
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR--VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF

LEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQ----GHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEILVRTGHNRAVDWWSLGALMYDM
 |. ..||.|||.||. .|||.||..|||||||| ....    ||||..|||. |... |  .. |||.|..|||||.| | || .|.||||.|.||| |
SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM

LTGSPPFTAENRKKTMDKIIKGKLVL-------PPYLTPDARDLAKKFLKRNPTQRIGGGLGDAADVQRHPFF
||| .|| . .|. .|..| . ||..       . .... | ||  . |.|.|..| | |  ..... .||.|
LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase p70S6Kb.AA RSK-Unclassified 67-328 43 3.3e-117 369.85 In-house 1-283 (283) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-283/283
Sequence Identity: 43% (124 aa)

FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLE--REG
|.    .|.|  |||. ||| ..|.  .||||||| | |..   | .     |.||.   .||||| | ..|||  .|||..|   ||..| ||   .| 
FIKHRLIGQGDFGKVYLVRK-KDTQ--QIYAMKVLHKHKMIRHNK-IKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEK

IFLEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCKES---------------------IHEGAITHTFCGTIEYMAPEILVR
 | || . ||..|.|.|| .||  ..|||||||.||.|   ||..||||.| ..                      . .|  |  |||| ||.|||.. |
CFCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRR

TGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLP--PYLTPDARDLAKKFLKRNPTQRIGGGLGDAADVQRHPFF
 || .||||| || .|| || | ||. ..|.  |   | |... .|   |.  ..||| || |.|||  | | . |||.|. |||||
CGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase p70S6Kb.AA AktR 67-328 44 2.2e-110 372.99 In-house 1-268 (268) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-268/268
Sequence Identity: 44% (120 aa)

FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILE-SVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGI
|... .||||..|||. |.|    . .|.||||...| ||.   .   ||. ||||.|  ..||||| | |.|||  ||..|.|   |||||.|| ... 
FHVYKCLGKGAFGKVYLVQKKR--DNQKQYAMKMIKKKKII-ERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKK

FLEDTACFYLAEITLALGHLHSH-GIIYRDLKPENIMLSSQGHIKLTDFGLCK-ESIH-EGAITHTFCGTIEYMAPEILVR-TGHNRAVDWWSLGALMYD
| |..| || |.| ||| .||.|  |||||||||||.| . ||.|.||||| | . .  .  ....|||| ||||||.. .  |||..||||..|.. | 
FSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYE

MLTGSPPFTAENRKKTMDKIIKGK-LVLPPY--LTPDARDLAK-KFLKRNPTQRIGGGLGDAADVQRHPFF
|.|| |||...|..   .||..   .  |..  ... ..|| . | |..||..|.| .  .. .. .||.|
MVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase p70S6Kb.AA PKA 67-328 42 4.8e-110 371.9 In-house 1-263 (263) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-263/263
Sequence Identity: 42% (116 aa)

FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESVKHPFIV-ELAYAFQTGGKLYLILECLSGGELFTHLEREGI
||.. .||.| .|.| ..|. ...   ..||||.|.|..||   | . |.  |.||| ..|||||| .. . ||.  .||...|  .|||.|..| ..| 
FEIIQTLGTGSFGRVMLCRHKHSG---NYYAMKMLKKQEIV-RLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGR

FLEDTACFYLA-EITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEILVRT-GHNRAVDWWSLGALMYDML
| ...|.|| | .|.|||  |||. |||||||||||.. ..||||.||||  |. . .   | | ||| ||.||||. .. ||...||||.|| | | ||
FSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEML

TGSPPFTAE--NRKKTMDKIIKGKLVLPPYLTPDA---RDLAKKFLKRNPTQRIGGGLGDAADVQRHPFF
.| |||...  .  .. .||..||.  |.....||   .|| || | ...|.|.|   ... |. .|..|
AGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase p70S6Kb.AA S_TKc 67-328 36 1.6e-105 357.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-231/231
Sequence Identity: 36% (100 aa)

FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSG--GELFTHLEREG
.|.| ..|||..|||...|..     |.|.|.|...            |.| |..||.. .||.|| | ..||. ..||...|...|  |.||..... |
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

I------FLEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEILVRTGHNR-AVDWWSLGA
       | | .|.||...| .|| ..||||||.||||||||.|..  |||..||||...        .||||| .|||||.|   |... ..||||.| 
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLAKKFLKRNPTQRIGGGLGDA--ADVQRHPFF
..| ||.| |||   . .....||           .|.|.|. .| |...|..|..     .   |.  ||.|
ILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase p70S6Kb.AA MSK 70-323 40 7.4e-105 354.66 In-house 1-277 (277) Show / Hide 
Range on Protein: 70-323
Range on HMM: 1-277/277
Sequence Identity: 40% (112 aa)

LSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESV-KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLE
|.|||.|||||.| .||. . . ||.||||.|.|| .| ..| ..||..|| .|| . .||.||.| ||||.  ..||..| ..|||||||. . . | |
LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDE

DTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQ---GHIKLTDFGLCKESIHE-GAITHTFCGTIEYMAPEILVR-----TGHNRAVDWWSLGALM
. . ....|. .|. |.|. |||.||||||||.. ..   ||.||.|||. ..   .    ....|.|..|||||.| |     .|.. |.||||||...
SECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVIL

YDMLTGSPPFT--AENRK-------KTMDKIIKGKLVLP----PYLTPDARDLAKKFLKRNPTQRIGGGLGDAADVQ
| ||||  ||.  .. |.         | .| ||.  .|        |||.|| .. | ..|  | | .  .|  . 
YTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase p70S6Kb.AA Pkinase 67-328 29 5.2e-90 310.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGG----ELFTHLE-
.......|.|..|.|.. ...     |||.|.|...| .. .. . |.  ..|  |. ...||.||.| ..|......|...|.. ||    .||.... 
YHIGRKIGSGSFGCVYKCHHKGT---GKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-REGIF--LEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQGHI----KLTDFGLCKES-IHEGAITHTFCGTIEYMAPEILV-RTGHNRAVDW
 |.| |   |....||. .|  .| ..||.|||.||||||||.....|||    |..||||.|   .  .  ..|||||..|||||..  .... ..||.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGALMYDMLTGSPPFTAE------NRKKTMDKIIKGKLVLPPYLT---------------------PDARDLAKKFLKRNPTQRIGGGLGDAADVQRH
||.| ..| ||.| |||  .      . .. ...| ...|  . . .                     ....|. |. |...|..|..     |...  |
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQH

PFF
|.|
PWF
Kinase p70S6Kb.AA S_TK_X 329-391 39 1.4e-28 102.22 SMART 1-79 (79) Show / Hide 
Range on Protein: 329-391
Range on HMM: 1-79/79
Sequence Identity: 39% (31 aa)

RHINWDDLLA--RRVDPPFRPSLQ----SEEDVSQFDARFTRQTPVDSPDDTALSESANQA----------FLGFTYVA
|.|.||.|..  ... |||.| ..    |..|.|.||  ||..||...|||..||.|..|           |.|||||.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase p70S6Kb.AA Pkinase_C 348-393 40 5.3e-16 59.55 Pfam 1-46 (46) Show / Hide 
Range on Protein: 348-393
Range on HMM: 1-46/46
Sequence Identity: 40% (19 aa)

SLQSEEDVSQFDARFTRQTPVDS-PDDTALSESANQAFLGFTYVAPS
 . |..|.| ||  ||...|.|. ||.. .|.... .| |||||.|.
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase p70S6Kb.AA TyrKc 67-316 19 2.4e-13 -6.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 67-316
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESV--KHPFIVELAYAFQTG-------GKLYLILECLSGGELF
 .|. .|| | .|.|.. .           | |.|.. .        .  . | .|. ..  .|| || |  .  ..       . |....|  ..| | 
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

THLEREGI-FLEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHE-------GAITHTF--CGT----IEYMAPEILVR
 .| . .  .  .. . .   |     .|||...| |||   |.........| .||||...  ..         ....   .|     |  |||| .  
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

TGHNRAVDWWSLGALMYDMLT-GSPPFTA-----ENRKKTMDKIIKG-KLVLPPY--------LTPDARDLAKKFLKRNPTQR-----IGGGL
   . . | || | .|. ..| | .|         . .  . .. .|  .  ||.         ...  .. |.  ...| .|     |   .
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase p70S6Kb.AA Pkinase_Tyr 121-217 23 0.00064 13.9 Pfam 55-159 (270) Show / Hide 
Range on Protein: 121-217
Range on HMM: 55-159/270
Sequence Identity: 23% (25 aa)

NILESV-KHPFIVELAYAFQ-TGGK--LYLILECLSGGELFTHLER----EGIFLEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTD
.|. .  .|| || |  .    |.   .|...|   .| | ..| .    .. .   . . . ..|  .. .|.|...| |||   |.........| .|
KIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICD

FGLCK
|||..
FGLAR
Kinase p70S6Kb.AA Pkinase_Tyr 67-83 29 4.3831 0.91 Pfam 1-17 (270) Show / Hide 
Range on Protein: 67-83
Range on HMM: 1-17/270
Sequence Identity: 29% (5 aa)

FELLSVLGKGGYGKVFQ
 ... .||.| .|.|..
ITFGKKLGEGAFGEVYK