Gene SgK269 (Mouse)

SgK269

Species: Mouse
Alias: SgK269, C230081A13Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: NKF3

Sequence

Name Sequence Type Origin Length Description Download
SgK269.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 338 Kinase domain by global Sugen HMM Fasta, JSON
SgK269.NA RNA Sugen 6936 None Fasta, JSON
SgK269.AA Protein Sugen 1735 None Fasta, JSON

Protein domain

Protein domains of SgK269.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SgK269.AA NKF3 1319-1655 68 0.0 894.65 In-house 1-360 (360) Show / Hide 
Range on Protein: 1319-1655
Range on HMM: 1-360/360
Sequence Identity: 68% (247 aa)

TSDKPCCEAGDAVYYTASYAKDPLSNYAVKICKSK--AKESQQYYHSLAVRQSLPVHFNIQQDCGHFLAEVPSRLLPWEDPDAPEKAEDGTEDSEEEGKA
|.|||||..||||||.|...|||.||||||||...  ||.||||.|...|.||.|||||||||||||.||||||.|.|||||||||.||..||.||..||
TCDKPCCRSGDAVYYCATHPKDPGSNYAVKICCDPNKAKQSQQYCHMTKVMQSHPVHFNIQQDCGHFIAEVPSRMLQWEDPDAPEKDEDDMEDTEEDAKA

ETLGGNPEPCSETEPSQKENQRVTNRKQRSHVVVITREVPHLTVADFVRDSLAHHGNSPDLYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQH
||.|.||.||.||.|.|.|||||.||||...||||||||||.|||||||||.|||...|..||||||..|||||.||.|||..|..||||.|||||||..
ETDGKNPSPCLETHPPQQENQRVMNRKQQDCVVVITREVPHQTVADFVRDSMAHHEHEPEVYERQVCFMLLQLCQGLCHLKEHHMCHCDLCLENLLLVHC

QP-GGAAQGPSPADP-----------CPTLACP--------TRLIVSNFSQAKQKS-HLVDPQILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLP
|| ||..|||.||||           |||.|||        .|||.|||.|||||| |.|.||..|||.||||||.||.||.||.|||||||||||||.|
QPQGGPHQGPTPADPTTTARCPSAAPCPTTACPEGPREKQLPRLIISNFMQAKQKSGHTVNPQQKRDQARLAPEIVTAKQYQKCHEFQTGILIYEMLHQP

NPFDENPELKEKEYTRTDLPRIPLRSPYSWGLQQLASCLLNPNPSERILISDAKGILQCL
||||..|.|.|..|||.||||||.||||||||||||.||||.||..||....||.|||||
NPFDTRPQLRERDYTRDDLPRIPVRSPYSWGLQQLAHCLLNKNPQDRIRCNQAKRILQCL
Kinase SgK269.AA S_TKc 1333-1655 13 1.7e-08 -52.24 SMART 16-231 (231) Show / Hide 
Range on Protein: 1333-1655
Range on HMM: 16-231/231
Sequence Identity: 13% (47 aa)

YTASYAKDPLSNYAVKICKSKAKESQQYYHSLAVRQSLPVHFNIQQDCGHFLAEVPSRLLPWEDPDAPEKAEDGTEDSEEEGKAETLGGNPEPCSETEPS
| .   |     .|.|| |                                                                              |  
YKCRHKK-TGRIVAIKIIK------------------------------------------------------------------------------EHI

QKENQRVTNRKQRSHVVVITREVPH----LTVADFVRD---SLAHHGNSPD-------LYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQHQP
..| |   .   .   .|   .| .      | ...     .| ..  .         . | ... .. |.|..||..   .. |.||  ||.|| .   
RREIQILKK---HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---

GGAAQGPSPADPCPTLACPTRLIVSNFSQAKQKSHLVDPQILRDQSR--LAPEIITATQYK--KCDEFQTGILIYEMLHLPNPFDENPELKEKEYTRTDL
                    .. .. |  |.|             ..  .|||..   .|   |||    |...||||    ||.   . .  .  .   
--------------------HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---

PRIPLRSPYSWGLQQLASCLLNPNPSERILISDAKG------ILQCL
         |  . .. . .|. .|..|. . .|        . . .
---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SgK269.AA CAMK 1479-1516 31 3e-06 15.57 In-house 444-481 (425) Show / Hide 
Range on Protein: 1479-1516
Range on HMM: 444-481/425
Sequence Identity: 31% (12 aa)

ERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQH
||... .  |.||.....   .. |.|| .||.||...
EREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDN
Kinase SgK269.AA Ciliate-E2-Unclassified 1566-1649 20 7e-06 16.33 In-house 233-347 (352) Show / Hide 
Range on Protein: 1566-1649
Range on HMM: 233-347/352
Sequence Identity: 20% (24 aa)

LAPEIITA-TQY----KKCDEFQTGILIYEMLHLPNPF-DENPEL------------KEKEYTRTDLPRIPLRSPYSW-----GLQQLA----S----CL
.|||..    ..    .||| .  |...||||    || |.| |              .|.. .  . ...  ....|     .... |    .    ..
TAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKM

LNPNPSERILISDAK
|. ||..|| .....
LKKNPNKRITFEQIL
Kinase SgK269.AA DCAMKL 1479-1519 34 1.1e-05 13.02 In-house 114-154 (279) Show / Hide 
Range on Protein: 1479-1519
Range on HMM: 114-154/279
Sequence Identity: 34% (14 aa)

ERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQHQPG
||.  .....||. |..|    . | |. .||||...|. |
ERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG
Kinase SgK269.AA AMPK 1477-1513 43 1.5e-05 12.5 In-house 97-133 (254) Show / Hide 
Range on Protein: 1477-1513
Range on HMM: 97-133/254
Sequence Identity: 43% (16 aa)

LYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLL
| ||. | .. |  ||.| .    . | || .|||||
LQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLL
Kinase SgK269.AA CAMKL 1475-1517 19 3.9e-05 12.18 In-house 118-164 (297) Show / Hide 
Range on Protein: 1475-1517
Range on HMM: 118-164/297
Sequence Identity: 19% (9 aa)

PD----LYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQHQ
..    . |.. . .  |..|.....   .. | |. .||.|| ...
GHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENG
Kinase SgK269.AA Ciliate-E2a 1479-1513 30 0.000265 8.6 In-house 100-135 (275) Show / Hide 
Range on Protein: 1479-1513
Range on HMM: 100-135/275
Sequence Identity: 30% (11 aa)

ERQVCLLLLQLCS-GLEHLKPYHVTHCDLRLENLLL
. ..| .. || . ||.... ... | ||..||.|.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILF
TyrKc SgK269.AA TyrKc 1318-1652 10 0.00035 -155.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 1318-1652
Range on HMM: 1-280/280
Sequence Identity: 10% (43 aa)

LTSDKP--CCEAGDAVYYTASYAKDPLSNYAVKICKSKAKESQQYYHSLAVRQSL-PVHFNI--------QQ--------------------DCGHFLAE
.| .|   ... |  .  |..       . ||| .|. |   .  .. . .  .| . | ||        ||                    |. ..| .
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

VPSRLLPWEDPDAPEKAEDGTEDSEEEGKAETLGGNPEPCSETEPSQKENQRVTNRKQRSHVVVITREVPHLTVADFVRDSLAHHGNSPDLYERQVCLLL
   .                                                                                      |  .. .   
HRPK--------------------------------------------------------------------------------------LCMKDLLSFC

LQLCSGLEHLKPYHVTHCDLRLENLLLVQHQPGGAAQGPSPADPCPTLACPTRLIVSNFSQAKQKSHL----VDPQILRD----QSR-------LAPEII
.| ..| |.|   .. | ||   | |.   .                     .  .| |  ..   .     .  .  |     ...       .||| |
WQIACGMEYLHSKNCIHRDLAARNCLVGENH---------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

TATQYKKCDEFQT-----GILIYEMLHLPNPFDENPEL--KEKEYTRTDLPRI--PLRSPY---------SWGLQQLASCLLNPNPSERILISDAKGIL
   .|.|.  ...     |....|.. .  .  .....  .. .  . .. .   . . |.         .  . |. ..  . .|..|   |. . ..
---NYGKFT-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase SgK269.AA NKF2 1576-1642 29 0.000371 10.59 In-house 279-355 (365) Show / Hide 
Range on Protein: 1576-1642
Range on HMM: 279-355/365
Sequence Identity: 29% (23 aa)

YKKCDEFQTGILIYEMLHLPNPFDE----------NPELKEKE--YTRTDLPRIPLRSPYSWGLQQLASCLLNPNPSER
| | |    | ..|| . . |||            .  |      |   .||  | . |   .|.||   ||...||.|
YEKADTWACGAIAYEIFGQKNPFYSSSGGMAREQGEMHLDSCNSDYQEDQLPQMPQSCPP--VLRQLVYNLLQRDPSKR
Kinase SgK269.AA Kin4 1477-1516 45 0.00038 7.94 In-house 107-146 (273) Show / Hide 
Range on Protein: 1477-1516
Range on HMM: 107-146/273
Sequence Identity: 45% (18 aa)

LYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQH
| | . | |  || || . .    . | ||.|||||| .|
LKEMNACRLFAQLISGVHYMHYKGLVHRDLKLENLLLDKH
Kinase SgK269.AA MAPKAPK 1479-1518 35 0.000466 9.43 In-house 103-142 (268) Show / Hide 
Range on Protein: 1479-1518
Range on HMM: 103-142/268
Sequence Identity: 35% (14 aa)

ERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQHQP
||..  .  | |. ..|.    . | || .||||..  ||
EREAAQIMKQICQAVQHCHSMNIAHRDLKPENLLYKDTQP
Kinase SgK269.AA CAMK 1567-1649 19 0.007551 4.21 In-house 288-420 (425) Show / Hide 
Range on Protein: 1567-1649
Range on HMM: 288-420/425
Sequence Identity: 19% (26 aa)

APEIITA-------------TQY--KKCDEFQTGILIYEMLHLPNPFDEN---------------PELKEK----EYTRTDLPRIPLR---SPYSWG---
|||..                .|  .|||    |.. | ||    ||..                .||.||    .|.  . .  |.    .|  |.   
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDIS

----------LQQLASCLLNPNPSERILISDAK
           ..| ...|...|..|. |....
DEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCL