Gene TBCK (Mouse)

TBCK

Species: Mouse
Alias: TBCK, A630047E20Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: TBCK

Sequence

Name Sequence Type Origin Length Description Download
TBCK.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON
TBCK.AA Protein Sugen 893 None Fasta, JSON
TBCK.NA RNA Sugen 3396 None Fasta, JSON

Protein domain

Protein domains of TBCK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TBCK.AA TBCK 18-273 40 2.9e-176 591.86 In-house 1-346 (346) Show / Hide 
Range on Protein: 18-273
Range on HMM: 1-346/346
Sequence Identity: 40% (139 aa)

ALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGK--HERLVVVAEHCERSLED----LLRERKPVSHSTVLCIAYEVLEGLHYLNKHG
...||.|..||||.|||....|||||.||...||.||||.|.||||  |||..||.||....|||    ......|...|..|||.|..|.||.|..||.
QEKHDRCCINGLPVTPNAKQMLGRFQYLKSLQHPNLCQYLDFSRGKIHHERMIVVMEHYKMNLEDQIEIYAKRHTPKDCSQILCIYYQILCGLSYMHKHH

IVHRALSPHNILLDRKG----HIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIPKTTDHVPSEKPLP-------SGPKSDVWSLGIILFELCVG
||||.|.||||.||..|    |.|||..||||||.||.||.||||||.|.|||.|.||..|||||.|...|||       |.|||||||||.|..|.|.|
IVHRFLHPHNIYLDDNGNQKLHVKLANYGLYHMTNHGKDVPFPIGYPRYMAPERILQGEMKTTDHMPPTNPLPPKTTNLSSNPKSDVWSLGCIMLEICLG

RKLFQSLDVSERVKFLLTLG------------------------------------------------------------CVDDTIIVLAEEHGCLDI--
..|.|.|..||........|                                                            |.......||.||.|...  
ICLWQELTLSEVLNKIMHYGTHSTTQSFNSISKSFEQCELKKTIINEKQHEEYEEYDDDEDISEEEKEKRIKDIKLNDQDCMNHFMEDLAREHQCHQRSN

-----------IKELPENVINILKKCLTFHPSKRPTPDELMKDQVF
           .....|..|.|..|||...|.|||.|.|||....|
SGSSNSNIGIPYHQMCEWLIQIIRKCLQMCPMKRPSPTELMEHPMF
Kinase TBCK.AA Pkinase 43-221 28 7.7e-29 103.05 Pfam 52-233 (293) Show / Hide 
Range on Protein: 43-221
Range on HMM: 52-233/293
Sequence Identity: 28% (57 aa)

QILKTITHPRLCQYVDISRGKHERLVVVAEHCER-----SLEDLLR--ERKPV--SHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDRKGHI---
||.| . ||  ... |. .  . .. .| |.||      .| |...  .....  |  .. ...|..|.|| |. ..||.|| | | |||.|..|||   
QIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDAC

-KLAKFGL-YHM-TAHGDDVDFPIGYPSYLAPEVIAQGIPKTTDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSL----DVSERVKFLLTLGC
 |.. |||  .. . ..   . . | | |.|||||              .  . |||.|.||.|.||.|.. || .|..     ........ ...|.
VKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-------------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGP
S_TKc TBCK.AA S_TKc 1-273 23 1.1e-28 102.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-273
Range on HMM: 1-231/231
Sequence Identity: 23% (69 aa)

MFPLKDAEMGAFTFFASALPHD---------VCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCER---SLEDLLRERKP-
   |.    |||     .  ..         .            ..|.   ||||   || .... |. .   ..| .| |.|.    .| |....|.. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----VSHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDRKGHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIPKTTDHVPSEKPLPSG
      .  .. ...|.....| |. .|||.|| | | |||||.  |||.. |||          .  .| | |.||||.                 . |
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-----------------GYG

P-KSDVWSLGIILFELCVGRKLFQSLDVSERVKFLLTLGCVDDTIIVLAEEHGCLDIIKELPENVINILKKCLTFHPSKRPTPDELMK-------DQVF
. |.|.||.|.||.|...|. .|.  .. .  | ..                         .. ......|||.. |.||||  |...       .. |
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TBCK.AA Ciliate-E2 43-273 17 3.2e-27 90.47 In-house 84-365 (365) Show / Hide 
Range on Protein: 43-273
Range on HMM: 84-365/365
Sequence Identity: 17% (57 aa)

QILKTITHPRLCQYVDISRG-KHERLVVVAEHCER-SLEDLLRER-----------KPVSHSTVLCIAYEVLE---------------GLHYLNKHG-IV
.||... || ......     . . .  | | |.  .|.|.....           |. ..  .. | ...|.               .|.|| . . |.
NILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNII

HRALSPHNILLDRKGHIKLAKFGL-----------------YHMTAHGDDVDFPIG----------------YPSYLAPEVIA------QGIPKTTDHVP
|| . | |||.     ||.. |||                 . ..  . | .  .|                 | |.|||..       |          
HRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ----------

SEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDVSERVKFLLTLGCVDDTIIVLAEEHGCLDIIKE--------------------------LPENVIN
 .|  . . |.|.||||.||.|.. |.  |                               ...||.                          .......
-QKQKGYDYKCDIWSLGVILYEMLFGKPPF-------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKD

ILKK----CLTFHPSKRPT-PDELMKDQVF
..||    .|   |.||.| ...... . |
LIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase TBCK.AA Ciliate-E2-Unclassified 77-273 19 1.1e-25 86.1 In-house 107-352 (352) Show / Hide 
Range on Protein: 77-273
Range on HMM: 107-352/352
Sequence Identity: 19% (51 aa)

SLEDLLRERKP-----------------VSHSTVL-----CIAYEVLEGL-HYLNKHGIVHRALSPHNILLDRKG---HIKLAKFGLYH-----------
.|.. ...||                  ..   ..      .....|.|| ..  |..|.|| . | |||.| .|   .||.. ||.             
DLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTN

----MTAHGDDVDFPI-GYPSYL----APEVIAQGIPKTTDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDVSE------------RVKFLLT
    |    ..    . | |.|.    ||||. .  . ..             |.|.||||.||.|.. |.  |.. .  .            . | |. 
QQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----------YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

LGCVDDTIIVLAEEHGCLDIIKELPENVIN-ILKKCLTFHPSKRPTPDELMKDQVF
  .  .. .  ...    ... .  .. || .|.|.|   |.||.|...... . |
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase TBCK.AA TKL 77-269 18 2.2e-24 84.74 In-house 124-362 (364) Show / Hide 
Range on Protein: 77-269
Range on HMM: 124-362/364
Sequence Identity: 18% (47 aa)

SLEDLLRERKPVSHSTVLCIAYEVLEGLHYLNKHG--------IVHRALSPHNILLDRKGH--------------IKLAKFGLYH-MTAHGD--------
||...|       ..  . .|...  |..||  ..        |.|| | ..|||.|....              .|.. |||   |. .|.        
SLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTM

-----------DVDFPIGYPSYLAPEVI--------AQGIPKTTDHVPSEKPL----PSGPKSDVWSLGIILFELCVGRKLFQSLDVSERVKFLLTLGCV
               ..| | ..||||.        . ||         ..      .  .|.||.| ||.|.|.. ... .. .. .... . . .   
MESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGI---------DE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDP-F---

DDTIIVLAEEHGCLDII-------------KELPENVINILKKCLTFHPSKRPTPDELMK
 . ..... ..|.   |             .  |. .......|    |.|||. .|..|
-EEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILK
Kinase TBCK.AA STE 43-201 23 1e-21 73.53 In-house 80-265 (359) Show / Hide 
Range on Protein: 43-201
Range on HMM: 80-265/359
Sequence Identity: 23% (47 aa)

QILKTIT--HPRLCQYVDISRGK------HERLVVVAEHCE-RSLEDLLRER--------------KPVSHSTVLCIAYEVLEG-LHYLNKHGIVHRALS
.|.|     ||   .| .    .      .. | .. |...  ||.|.....              .... | . .|....|.| |.|| .|.|.|| . 
KIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIK

PHNILLDRKGHIKLAKFGLYH-MTAHGD------------DVD----FPIGYPSYLAPEVIAQGIPKTTDHVPSEKPLPSGPKSDVWSLGIILFELCVGR
| ||||     .||. ||.   .| ...            . .      .| | . ||||| |.  . .         . . |.|.||||. . |.. |.
PANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R-------DKGYDTKCDIWSLGCTIIEMATGK
Kinase TBCK.AA CAMK 43-195 18 3.7e-19 57.71 In-house 83-325 (425) Show / Hide 
Range on Protein: 43-195
Range on HMM: 83-325/425
Sequence Identity: 18% (47 aa)

QILKT-------ITHPRLCQYVD-----------ISRG-KHER--------LVVVA---EHCER-----SLEDLLRERKP---------------VSHST
.|.|.       . || ...  .           .. .   ..        .. |    |.|.       | | ..|...               .. . 
EIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTERE

VLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDRK-----------------GHIKLAKFGLYHMTAH------------------------GDDVDFPI
.  .   .....||. .|.|||| | | ||||| .                 . ||.. ||.  .  .                        |.    . 
ARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFC

GYPSYLA-PEVIAQ-------GIPKTTDHVPSEKPLPSGPKSDVWSLGIILF
| |.| | |||. .       .   |     .|.  . |||.|.||.|.||.
GTPEYMAAPEVLNGKGHCNMQN-A-T-----DEEKPYYGPKCDMWSCGVILY
Kinase TBCK.AA CMGC 62-137 20 3.4e-15 45.48 In-house 119-250 (513) Show / Hide 
Range on Protein: 62-137
Range on HMM: 119-250/513
Sequence Identity: 20% (27 aa)

GKHE------RLVVVAEHCERSLEDLLRERK---------PVSHST------------VLCIA------YEVLEGLH--YLNKHG--IVHRALSPHNILL
.||.       |  | |... .| ..... .         | |.              . ..       | .|.||.  |. .|.  |.|| | | |||.
DKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILI

DRK--------------------GHIKLAKFGL
. .                    |..|.. |||
NHNCELITRMMWKSEDWNPCQKNGRLKICDFGL
Kinase TBCK.AA ULK 43-137 22 1.6e-14 47.18 In-house 62-188 (329) Show / Hide 
Range on Protein: 43-137
Range on HMM: 62-188/329
Sequence Identity: 22% (28 aa)

QILKTIT--------HPRLCQYVDISRGKHE-RLVVVAEHCER-SLEDLLRERKP----------VSHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNI
.|.|..         ||  ... |... ...  .  . | |.   ||... ..|.           | . .. . .  |.|. .|.||.|.|| . | ||
KIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNI

LLDRK------------GHIKLAKFGL
|.. .            |..|.| ||.
LIHNGQPKTDSKKVHPNGVLKIADFGF
Kinase TBCK.AA PEK 72-137 21 1.8e-13 42.56 In-house 363-478 (655) Show / Hide 
Range on Protein: 72-137
Range on HMM: 363-478/655
Sequence Identity: 21% (25 aa)

EHCE-RSLEDLLRERK--------------------------------------------PVSHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDR
|.||  .|.|......                                             ... ... |. ..|||| |.  .|..|| | |.||.||.
EYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIFLDC

KGH-----IKLAKFGL
.|.     .| . |||
DGQHHQMQVKIGDFGL
Kinase TBCK.AA ULK 43-137 22 2.2e-13 43.9 In-house 62-184 (324) Show / Hide 
Range on Protein: 43-137
Range on HMM: 62-184/324
Sequence Identity: 22% (28 aa)

QILKTIT---HPR--LCQYVDISRGKHE-RLVVVAEHCER-SLEDLLRERKP---------VSHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDR
||.|..    ||    ... |... ...  .  . | |.   ||... ..|.          | . .. . .  ..|. .|.||.|.|| . | |||.  
QIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHN

K------------GHIKLAKFGL
.            |..|.| ||.
GQPKTDSKKVHPNGVLKIADFGF
TyrKc TBCK.AA TyrKc 1-272 17 6.2e-11 -45.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-272
Range on HMM: 1-280/280
Sequence Identity: 17% (56 aa)

MFPLKDAEMGAF---------------TFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTI--THPRLCQYVDISRGKH------ERLVVVAEHCER-
   .|    |||               .  ..|                   ..   .|.. .   || . . . . . .       | | .| |...  
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

SLEDLLRERKP-VSHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDRKGHIKLAKFGL---------------YHMTAHGDDVD--FPIGYPSYLA
.| | ||...| ..... | ... . .|  || .....|| |   |.|.......| . |||               | ... ... .  .||     .|
DLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI---RWMA

PEVIAQGIPKTTDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDVSERVKFLLTLGCVDDTIIVLAEEHGCLDIIKE--------LPENVINIL
||.|  |.                .|||||| |. ..|..   .   . .. .         . .. .| . .. . ... ..         |. . .| 
PECINYGK--------------FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIM

KKCLTFHPSKRPTPDELMKDQV
|.|  . |..|||  |. ... 
KQCWHEDPEDRPTFSEI-HECF
Kinase TBCK.AA Pkinase_Tyr 43-137 24 1.7e-08 29.42 Pfam 55-157 (270) Show / Hide 
Range on Protein: 43-137
Range on HMM: 55-157/270
Sequence Identity: 24% (25 aa)

QILKTI-THPRLCQYVDISRGKHER--LVVVAEHCER-SLEDLLRE----RKPVSHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDRKGHIKLAK
.|.|..  || . ... .   . |   . .| |...  .| | ||.    ..|..... |...... .|. ||  ....|| |   |.|.......| . 
KIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICD

FGL
|||
FGL
Kinase TBCK.AA CMGC 240-273 32 2.9e-07 18.95 In-house 480-513 (513) Show / Hide 
Range on Protein: 240-273
Range on HMM: 480-513/513
Sequence Identity: 32% (11 aa)

KELPENVINILKKCLTFHPSKRPTPDELMKDQVF
| ...  |. |||.|.. |.||.|... ..   |
KCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase TBCK.AA STE 247-273 34 1e-06 19.34 In-house 331-359 (359) Show / Hide 
Range on Protein: 247-273
Range on HMM: 331-359/359
Sequence Identity: 34% (10 aa)

INILKKCLTFHPSKRPTPDELMK--DQVF
.. ..|||.  |.||||...|.|     .
KDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase TBCK.AA Pkinase 240-273 29 5e-06 22.34 Pfam 260-293 (293) Show / Hide 
Range on Protein: 240-273
Range on HMM: 260-293/293
Sequence Identity: 29% (10 aa)

KELPENVINILKKCLTFHPSKRPTPDELMKDQVF
....|. . ..|.||.. |.||||.......  |
HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TBCK.AA ULK 184-201 50 1.4e-05 15.52 In-house 236-253 (329) Show / Hide 
Range on Protein: 184-201
Range on HMM: 236-253/329
Sequence Identity: 50% (9 aa)

KSDVWSLGIILFELCVGR
|.|.||||.|..|. .|.
KCDIWSLGCIFYEMLYGK
Kinase TBCK.AA PEK 184-200 52 1.7e-05 14.25 In-house 574-590 (655) Show / Hide 
Range on Protein: 184-200
Range on HMM: 574-590/655
Sequence Identity: 52% (9 aa)

KSDVWSLGIILFELCVG
|.|..|||||.||....
KVDMYSLGIIFFEMWYP
Kinase TBCK.AA ULK 184-201 50 1.8e-05 15.48 In-house 232-249 (324) Show / Hide 
Range on Protein: 184-201
Range on HMM: 232-249/324
Sequence Identity: 50% (9 aa)

KSDVWSLGIILFELCVGR
|.|.||||.|..|.  |.
KCDIWSLGCIFYEMLYGK
Kinase TBCK.AA PEK 248-273 19 4.3e-05 12.84 In-house 630-655 (655) Show / Hide 
Range on Protein: 248-273
Range on HMM: 630-655/655
Sequence Identity: 19% (5 aa)

NILKKCLTFHPSKRPTPDELMKDQVF
......|   |..||.......   |
DFIQWMLSHDPQQRPSAQQILQHEFF
Kinase TBCK.AA CAMK 241-273 18 5.4e-05 11.24 In-house 393-425 (425) Show / Hide 
Range on Protein: 241-273
Range on HMM: 393-425/425
Sequence Identity: 18% (6 aa)

ELPENVINILKKCLTFHPSKRPTPDELMKDQVF
.. . ... ..|.|.  |.||.| .. .... .
FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase TBCK.AA CMGC 182-205 28 0.000233 9.21 In-house 313-344 (513) Show / Hide 
Range on Protein: 182-205
Range on HMM: 313-344/513
Sequence Identity: 28% (9 aa)

GPKSDVWSLGIILFELCVG--------RKLFQ
... |.||.| |..|.  |        . ||.
TTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFP
Kinase TBCK.AA ULK 244-273 13 0.000501 10.25 In-house 295-324 (324) Show / Hide 
Range on Protein: 244-273
Range on HMM: 295-324/324
Sequence Identity: 13% (4 aa)

ENVINILKKCLTFHPSKRPTPDELMKDQVF
..........|.. ...| . .|. .  .|
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase TBCK.AA ULK 244-273 16 0.00051 10.02 In-house 300-329 (329) Show / Hide 
Range on Protein: 244-273
Range on HMM: 300-329/329
Sequence Identity: 16% (5 aa)

ENVINILKKCLTFHPSKRPTPDELMKDQVF
..........|.. ...| . .|| .  .|
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase TBCK.AA Pkinase_Tyr 184-198 53 0.06883 7.02 Pfam 194-208 (270) Show / Hide 
Range on Protein: 184-198
Range on HMM: 194-208/270
Sequence Identity: 53% (8 aa)

KSDVWSLGIILFELC
|||||| |. ..|..
KSDVWSFGVLMWEIF
TBC TBCK.AA TBC 469-671 24 5.8e-55 193.7 Pfam 1-240 (240) Show / Hide 
Range on Protein: 469-671
Range on HMM: 1-240/240
Sequence Identity: 24% (60 aa)

PLMRGLTWAALLGV-----------------EGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQ-YD--ELLSSPEGHA-KFRRVLKAWVVSHPDLVYWQG
. .|.  |  |||.                 .   .  |  .....| |...||| |..|... ..  . .....|.  . |..|||. . .||. |.||
DQLRWQVWPYLLGYYPWMNGYYKRLYYQEKKQWYQMK-YQ-NNYHEPHPDYHQIEKDVHRTFPNHHHFFFFQNGQGQQVQLRNILKAYSNYNPDVGYCQG

LDSLCAPFLYLNFNNEAL-----AYACMSAFI--PKYLYNFFLKD-NSHVIQEYLT--VFSQMIAFHDPELSNHLNE--IGFIPDLYAIPWFLTMFTHVF
.  ..|||||. ...|       |. |.....   ..| .....| .  ..| ..   || . .  |||.| .|...  ..  |...|..||...|||.|
MNFIAAPFLYMYMMDEEDFQAEDAFWCFCQLMNENYHLRDYYTHDMPG-HLQRDFYFQVFEELLKKHDPKLYKHFQKDCLNIDPSMFATQWFMCLFTHCF

PLHKIFHLWDTLLL---GN--SSFPFCIGVA-IL-QQLRDRLL
|.  ....|| ...   |   . | | ...| ||  ..|. .|
PFETVLRIWDCFFFYCEGWNAKFFLFRFCLACILVKYHRQEIL
TBC TBCK.AA TBC 463-674 19 2.6e-48 167.74 SMART 1-310 (310) Show / Hide 
Range on Protein: 463-674
Range on HMM: 1-310/310
Sequence Identity: 19% (61 aa)

ARVDIPPLMRGLTWAALLGV-------------------------EGAIHAKYDAIDKDTPIPT--------------------------------DRQI
 .  ||. .||  |  ||.                          . . . .|| . . ..  .                                . ||
WWQGIPHHYRGWVWWLLLNCQPMNTSNWERMQYMWDGENCYFPVNWDRCKDYYDRMLNQHCPCDHHHDNWQDIMMNNNDHECCWMSYWHFFQDCWHWHQI

EVDIPRCHQYDELLSSP---------------EGHAKFRRVLKAWVVSHPD--LVYWQGLDSLCAPFLYLNF-NNEALAYACMSAFIPKYLYNFFL----
|.|..|... ...  ..               ... . ||||.|. . .|.  ..|.||.  ..||.|. .   .|. |..|.....  |. .|.     
EKDLRRTFPNHPFFQFRMRYNQHCIMLHDQNGPHQESLRRVLYAYSWHNPEHIVGYCQGMNFIAAPLLLHMPCYDEEDAFWCFCKLMERYCPWFYFCDDQ

---KDNSHVIQEYLTVFSQMIAFHDPELSNHLNEI------------GFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLG----NSSFPFCIGVAILQ
   . . . ... . .|....  |||.|..||.|             .. |..||..||||.|.. |||. ....|| ...      . |.|||..|.|.
NCYTPDMMGMHWQMYQFDHLLQEHDPDLYKHLQEQDHHSMKWHFDHLEIDPSMYAFRWFLTCFAREFPLEDVCRIWDCYFFEYGRHGHPFLFCIALAMLK

QLRDRLLANG
..|. || . 
MHRQKLLQHD
Rhodanese TBCK.AA Rhodanese 782-883 25 2e-17 56.94 Pfam 1-102 (102) Show / Hide 
Range on Protein: 782-883
Range on HMM: 1-102/102
Sequence Identity: 25% (29 aa)

TPTKKTKSS-KPKLLVVDIRNSEDFVRGHIAGS-INIPFSAAFTAEGELSQG--PYTTMLHNFKGKVI-VVVGHVAKQTAEFAAH-----LVKMKYP-RV
||.   .   .|.....|.|. |.. .||| |. .|||.         | .       .... |.| | ||..   .. . ..|      | .| || .|
TPEWLKEMMNDPDYVIIDVRPPEEYEKGHIPGAHVNIPW---------LEEEHDLEELGIKLDKDKPIIVVYC-HGNRSG-AWACLVWWMLKAMGYPPNV

CILDGGINKIRPT
 .||||... .  
YVLDGGWEAWKAE
RHOD TBCK.AA RHOD 780-886 22 9.7e-16 59.54 SMART 1-94 (94) Show / Hide 
Range on Protein: 780-886
Range on HMM: 1-94/94
Sequence Identity: 22% (24 aa)

FKTPTKKTKSSKPKLLVVDIRNSEDFVRGHIAGSINIPFSAAFTAEGELSQGPYTTMLHNFKGKVIVVVGHVAKQT-AEFAAHLVKMKYPRVCILDGGIN
  .  .| ... ......|.|. ... .||| |.||||....               |   |.| ..|.     .  .. |. | .. |..|.|||||..
V-PEWWKMLQN-EDCVIIDCRWPYEYEGGHIPGAINIPWDELLDR------------LGIDKDKPVIVYCRSGNRSAPRAAWWLREAGYKNVYILDGGWK

KIRPTGLL
. .  .. 
EWKRACPP