Gene C01H6.9 (Nematode worm)

C01H6.9

Species: Nematode worm
Alias: C01H6.9, CE07824, aSWK220
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: I: 7241182-7237498, WormBase Genetic Map location: No interpolated position.,

Classification

Group: Other
Family: Haspin

Sequence

Name Sequence Type Origin Length Description Download
C01H6.9.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 281 Kinase domain by global Sugen HMM Fasta, JSON
C01H6.9.AA Protein Genbank 920 None Fasta, JSON

Protein domain

Protein domains of C01H6.9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C01H6.9.AA Haspin 590-853 41 3.1e-134 452.27 In-house 1-264 (264) Show / Hide 
Range on Protein: 590-853
Range on HMM: 1-264/264
Sequence Identity: 41% (110 aa)

RVKKLGEGAYGEVFSTIWDGKPVAIKIVPFEKDGCNRQYFGEYHSEEMQTSDVVLPEVIVMKELSALRDEDAWNSTPNFIEMISAEVVMGKYPKGLLSAW
..||.|||.||||||..|.||.|..|| |.. . |.  |.|||..|..|| |..|.|.|.||....|.........|||..|.....|.||..|.|...|
NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCK--YYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMW

DSYDKLKESENTRPDVYSSIDQNFILFVSANGGIALEDF--VLESENELFSIIHQLVLSMNAAEAALEFEHRDLHLGNVLID-RNGVKELYYTVHGQKVP
| |.....|||.|||...  .|..|......||..|..|   ....|. .||..|||.|| .|.....|.|.|||.|||||. ....|.|.||..|....
DHYCYTHHSENDRPDFFK-KNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIK

LSTHGIKVNIIDFTLSRISKGATTVYWDLENDPAIFEGQDDPQFEVYREMRKNCKSNWKKFSRRTNL
. .||..|.||||..||..|. ...|||..|| ..||...|.||.|||.|||||...|........ 
IKSHGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFWDYQFDVYRDMRKNCQHFWFVHHAKNWK
Kinase C01H6.9.AA DUF3635 819-863 32 2.9e-09 33.52 Pfam 1-56 (121) Show / Hide 
Range on Protein: 819-863
Range on HMM: 1-56/121
Sequence Identity: 32% (18 aa)

PAIFEGQD---------DPQFEVYREMRKNCKS--NWKKFSRRTNLMWIVYIANRL
.  | |..         | ||..|| |||  |   .| .|. .||..|  |    |
HDFFQGKGKSKINEYQYDYQFDIYRMMRKMLKNPICWSQFHPMTNVLWLHYLIHKL
Kinase C01H6.9.AA MOS 589-617 34 6.2e-09 25.53 In-house 2-30 (299) Show / Hide 
Range on Protein: 589-617
Range on HMM: 2-30/299
Sequence Identity: 34% (10 aa)

RRVKKLGEGAYGEVFSTIWDGKPVAIKIV
 .   .| |..|.|.  .. | |||.|.|
CLCQMIGRGGFGSVWKAQYCGRPVAVKQV
Kinase C01H6.9.AA Src 588-615 41 4.1e-08 23.61 In-house 1-29 (255) Show / Hide 
Range on Protein: 588-615
Range on HMM: 1-29/255
Sequence Identity: 41% (12 aa)

GRRVKKLGEGAYGEVFSTIWDG-KPVAIK
 ....|||.| .|||.  .|.|  .||.|
IKLCRKLGQGQFGEVWMGYWNGNTKVAVK
Kinase C01H6.9.AA Src-Unclassified 589-615 42 5.3e-08 23.45 In-house 2-29 (284) Show / Hide 
Range on Protein: 589-615
Range on HMM: 2-29/284
Sequence Identity: 42% (12 aa)

RRVKKLGEGAYGEVFSTIWDG-KPVAIK
....||| |  |||.  .|.|   ||.|
HLLRKLGRGQFGEVWYGKWRGKVDVAVK
Kinase C01H6.9.AA TKL 594-622 30 9e-08 24.08 In-house 1-39 (364) Show / Hide 
Range on Protein: 594-622
Range on HMM: 1-39/364
Sequence Identity: 30% (12 aa)

LGEGAYGEVFSTIWDG----------KPVAIKIVPFEKD
.|.|..|||.  .| |          |.||.|. . . |
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHND
Kinase C01H6.9.AA SFK-Abl 592-615 58 1.8e-07 20.19 In-house 5-28 (251) Show / Hide 
Range on Protein: 592-615
Range on HMM: 5-28/251
Sequence Identity: 58% (14 aa)

KKLGEGAYGEVFSTIWDGKPVAIK
  |||| ||||.  ||  . ||||
HRLGEGQYGEVYKGIWNNHRVAIK
Kinase C01H6.9.AA Dicty4 589-623 31 2.7e-07 20.56 In-house 2-36 (277) Show / Hide 
Range on Protein: 589-623
Range on HMM: 2-36/277
Sequence Identity: 31% (11 aa)

RRVKKLGEGAYGEVFSTIWDGKPVAIKIVPFEKDG
 . ...|.|..|||.  .| || ||.|. .  ...
NIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQN
Kinase C01H6.9.AA TKL-Unique 590-616 51 2.9e-07 21.84 In-house 1-27 (290) Show / Hide 
Range on Protein: 590-616
Range on HMM: 1-27/290
Sequence Identity: 51% (14 aa)

RVKKLGEGAYGEVFSTIWDGKPVAIKI
 ..|.|||.||.|. ..| |.|||||.
FWNKIGEGGYGQVYKGKWRGYPVAIKQ
Kinase C01H6.9.AA MST 591-622 52 3.1e-07 18.95 In-house 4-37 (254) Show / Hide 
Range on Protein: 591-622
Range on HMM: 4-37/254
Sequence Identity: 52% (18 aa)

VKKLGEGAYGEVFSTIW--DGKPVAIKIVPFEKD
| |||.|.|| |.  |   .|| ||||.|| . |
VEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNED
Kinase C01H6.9.AA CMGC 588-626 20 4.3e-07 18.36 In-house 1-70 (513) Show / Hide 
Range on Protein: 588-626
Range on HMM: 1-70/513
Sequence Identity: 20% (14 aa)

GRRVKKLGEGAYGEVFSTIW----------------DGKPVAIKIVP---FEKDGC------------NR
   .||.|||.||.|.. .                 ... ||||..    .| ...            .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALR
Pkinase C01H6.9.AA Pkinase 588-618 30 1e-06 24.85 Pfam 1-33 (293) Show / Hide 
Range on Protein: 588-618
Range on HMM: 1-33/293
Sequence Identity: 30% (10 aa)

GRRVKKLGEGAYGEVFSTIWDGKP--VAIKIVP
 ....|.|.|..|.|.  .. | .  ||.||..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK
Kinase C01H6.9.AA S_TKc 588-905 11 5e-05 -103.14 SMART 1-231 (231) Show / Hide 
Range on Protein: 588-905
Range on HMM: 1-231/231
Sequence Identity: 11% (41 aa)

GRRVKKLGEGAYGEVFSTIW--DGKPVAIKIVPFEKDGCNRQYFGEYHSEEMQTSDVVLPEVIVMKELSALRDEDAWNSTPNFIEMISAEVVMGKYPKGL
 . ..|.|.||.|.|.  ..  .|. |||||..                              ...|.. |.        || . .. . .         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------------------EHIRREIQILKK-----HHPNIVKLYDVFQD--------

LSAWDSYDKLKESENTRPDVYSSIDQNFILFVSANGGI---ALEDFVLE----------SENELFSIIHQLVLSMNAAEAALEFEHRDLHLGNVLIDRNG
                          ... .|    .     | |.  .          .| .  ....|... ..       . ||||   |.|.|.  
--------------------------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--

VKELYYTVHGQKVPLSTHGIKVNIIDFTLSRISKGATTV-----------YWDL-END--------------PAIFEGQDDPQFEVYREMRKNCKSNWKK
                     . |.|| |.|.    | .            ..  . |                 |.     ...... ..         
--------------------HIKICDFGLARQL--TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---------

FSRRTNLMWIVYIANRLIDTKICPKGLLTEKRRMELKVLFDRFAEF-----GSCGESLT------NEEFF
                                  |.| . ..  ..      .. | |.      . ..|
--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase C01H6.9.AA Pkinase_Tyr 589-617 42 0.000165 15.89 Pfam 2-36 (270) Show / Hide 
Range on Protein: 589-617
Range on HMM: 2-36/270
Sequence Identity: 42% (15 aa)

RRVKKLGEGAYGEVFSTIWD------GKPVAIKIV
.  |||||||.|||.  .|.      . |||.|..
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML
Kinase C01H6.9.AA TKL 758-774 28 0.322768 0.15 In-house 163-194 (364) Show / Hide 
Range on Protein: 758-774
Range on HMM: 163-194/364
Sequence Identity: 28% (9 aa)

HRDLHLGNVLIDRNG---------------VK
||||   |.|.|.|.               .|
HRDLKSKNILVDENWTNVSNYMYNPNADWCCK