Gene C36B7.1 (Nematode worm)

C36B7.1

Species: Nematode worm
Alias: C36B7.1, aSWK177, CE04172
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 7116645-7118619, WormBase Genetic Map location: X:-2.04,

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK2

Sequence

Name Sequence Type Origin Length Description Download
C36B7.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 313 Kinase domain by global Sugen HMM Fasta, JSON
C36B7.1.AA Protein Genbank 450 None Fasta, JSON

Protein domain

Protein domains of C36B7.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C36B7.1.AA DYRK2 131-443 43 1.5e-195 641.83 In-house 1-318 (318) Show / Hide 
Range on Protein: 131-443
Range on HMM: 1-318/318
Sequence Identity: 43% (138 aa)

YSIDEVLSSGYYAQVFRCTDKKTDKKVCIKLK---NRNLSTTYEETIILLRIHQLNRQNNSNCVRMLDYDHFRGHHFIVLENYQTDLASYLCGRSK--LT
|.|.||...|...||..|.|.||...|.||..   .|.....|||..|| .|.. ...|..|||.||||..||.||.|..|.....|..|......  ..
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

PREYIPMIKSIVHGLKFLHQNKIIHGDLKPANVLLNEWNRNNLKLTDFGLSTFVNQGPFFRDYQTLYYKAPEVFCQGKVSVEIDIWSLGCVAAEIVRGTP
.........||...|.|||.|.|||.||||.|.||..|||...|..|||.|.|..|.......|...|.||||...||....||.||.||..||...|.|
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYP

LFVGDNYFDQFALIQEFFGKPSRKLFNTWGGIHQFYTEYFFPRHCFEWLNPFNGDRTMEIEPHYKLAHPSRKPPLTSSLVSKLPGGNQKFLARFLMRCFE
||.|.|..||||...|..|.|..|.|.||..||.|...|||..|||||...|..|..|||..||| .|..|.|| ..|..|.|.|........|..||||
LFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYCTFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGCEDENFIDFIKRCFE

WDPTERIKSSFILNHPFF
|||.||...|..|.||..
WDPSERMTPSQALKHPWI
Kinase C36B7.1.AA DYRK 131-443 32 6.00000000001e-144 484.51 In-house 1-320 (320) Show / Hide 
Range on Protein: 131-443
Range on HMM: 1-320/320
Sequence Identity: 32% (106 aa)

YSIDEVLSSGYYAQVFRCTDKKTDKKVCIKLKNRN---LSTTYEETIILLRIHQLNRQNNSNCVRMLDYDHFRGHHFIVLENYQTDLASYLCGRSK---L
| |.|.. .|...||..|.|.||...|.||. ..|   . ....|. || ...| .......||.|.||...|.|..|| |.....|  .|. ...   .
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

TPREYIPMIKSIVHGLKFLHQN-KIIHGDLKPANVLLNEW-NRNNLKLTDFGLSTFVNQGPFFRDYQTLYYKAPEVFCQGKVSVEIDIWSLGCVAAEIVR
. . . .....|...|||||.| .|||.|||| |..|... |....|. |||.|.|..|  ... .|  .|.||||..... ...||.|||||. ||.. 
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQ-RIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFT

GTPLFVGDNYFDQFALIQEFFGKPSRKLFNTW--GGIHQFYTEYFFPRHCFEWLN-PFNGDRTMEIEPHYKLAHPSRKPPLTSSLVSKLPGGNQKFLARF
| ||| |.|..||.|.|.|..|.|........    .|.|... |....|.|| .  ...|..|....|....  .|.|| .... ...   ... . .|
GWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC-FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDDHQFKDF

LMRCFEWDPTERIKSSFILNHPFF
...|..|||..||. |  |.||.|
IKKCLQWDPHKRITPSQALQHPWF
Kinase C36B7.1.AA CMGC 131-443 17 1.3e-80 264.44 In-house 1-513 (513) Show / Hide 
Range on Protein: 131-443
Range on HMM: 1-513/513
Sequence Identity: 17% (93 aa)

YSIDEVLSSGYYAQVFRCTD--------------KKTDKKVCIK---------------LKNRNLSTTYEETIILLRIH-QLNRQN----------NSN-
| |.... .| |..|..|.|              ..|...| ||               .|..  .... |  || ... . .  |          . | 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHNN

CVRMLDYDHFRG-----------------HHFIVLENYQTDLASYLCGRS---------KLTPRE------------YIPMI------KSIVHGLK--FL
.|...|. ....                 | ..| |  ..||. |.   .         .|.. .               ..      . |  |||  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HQNK--IIHGDLKPANVLLNEWNRN------------------NLKLTDFGLSTFVNQG-----------------------PFFRDYQTLYYKAPEVFC
|...  ||| ||||.|.|.|. ...                  .||. ||||......                        |.  . .|..|.|||. .
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

QGKVS----------VEIDIWSLGCVAAEIVRG--------TPLFV-----------GDNYFDQFALIQEFFGKPSRKLFNTWGGIHQFYTEYFFPRHCF
  |             .||.||.||. ||...|         |||            |... || ..| . .|.|. ......  .| |   . |..|  
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGK-RH-F---N-FCKHEE

EWLN----------------PFNGDRTMEIEPHYKLAH------PSRKPPLTSSLVSKLPGGNQ-------------------------------KFLAR
|| |                .   . | .. ......       | ..|.  ..|. ..| ..                                . .  
EWPNMIKLPWYNKFPKKWNWQ---TMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAID

FLMRCFEWDPTERIKSSFILNHPFF
.|......||..||. . .|.||.|
LLKKMLQYDPDKRITAEQALQHPYF
Kinase C36B7.1.AA S_TKc 131-443 20 2.7e-62 214.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 131-443
Range on HMM: 1-231/231
Sequence Identity: 20% (69 aa)

YSIDEVLSSGYYAQVFRCTDKKTDKKVCIKLKNRNLSTTYEETIILLRIHQLNRQNNSNCVRMLDYDHFRGHHFIVLENYQT---DLASYLCGRSK----
| | ... .| ...|..|..|||...| ||  .    ... |  || .       .  | |...|. .  .| ..|.|   .   || .|.. | .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LTPREYIPMIKSIVHGLKFLHQNKIIHGDLKPANVLLNEWNRNNLKLTDFGLSTFVNQGPFFRDYQTLYYKAPEVFCQGKVSV-EIDIWSLGCVAAEI
  ... .   ... |. .|...|...||| ||||.|.||.|    ..|..||||....          |..| ||||.   . .  ..|.||.||. .| 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VRGTPLFVGDNYFDQFALIQEFFGKPSRKLFNTWGGIHQFYTEYFFPRHCFEWLNPFNGDRTMEIEPHYKLAHPSRKPPLTSSLVSKLPGGNQKFLARFL
. | |.|   ...  | .|                                                                         . ..  |.
LCGYPPFP--QMQMMFKKIG-----------------------------------------------------------------------SPEAKD-FI

MRCFEWDPTERIKSSFILN-------HPFF
..|...||..|.    .|.       ||.|
RKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase C36B7.1.AA Ciliate-E2-Unclassified 131-443 17 4.4e-48 164.88 In-house 1-352 (352) Show / Hide 
Range on Protein: 131-443
Range on HMM: 1-352/352
Sequence Identity: 17% (70 aa)

YSIDEVLSSGYYAQVFRCTDKKTDKKV-----CIKLKNRN-LSTTYEETIILLRIHQLNRQN-------------------NSNCVRMLDYDHFRGHHFI
| | ... .| ...|..| .||.. ..      .| .... ..  ... .|.. ....|...                   . . |.|....  . . .|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VLENY-QTDLASYLCGRSK-----------------LTPREYI-----PMIKSIVHGLKFLHQNK-IIHGDLKPANVLLNEWNR-NNLKLTDFGLSTFVN
|.|   . ||  |.. |.|                 .| .. .      ... |. ||..||... ||| |.|| |.|... .. ...|..|||.| . .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

QGP-----------------FFRDYQTLYYK----APEVFCQGKVS----VEIDIWSLGCVAAEIVRGTPLFVGDNYFD----------------QFALI
| .                 .    .|..|.    ||||... . .     ..||||||... |.. |.. | . |. .                ..  |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

QE----FFGKPSRKLFNTWGGIHQFYTEYFFPRHCFEWLNPFNGDRTMEIEPHYKLAHPSRKPPLTSSLVSKLPGGNQKFLARFLMRCFEWDPTERIKSS
..    |.  | ..                                                         ...   . |. ..| ......| .||  .
KQKNIQFPKFPWQQ------------------------------------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFE

FILNHPFF
 |||||.|
QILNHPWF
Kinase C36B7.1.AA Ciliate-E2 131-443 15 5.8e-40 134.87 In-house 1-365 (365) Show / Hide 
Range on Protein: 131-443
Range on HMM: 1-365/365
Sequence Identity: 15% (70 aa)

YSIDEVLSSGYYAQVFRCTDKKTDK------------------KVCIKLKNRNLSTTYEETIILLRIHQLN----------------RQNNSNCVRMLDY
| . ... .| ...|..|...|..|                  || ||... .    ..  .|.  ||...                . |. | ..| ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

DH--FRGHHFIVLENYQT-DLASYLC------------GRSKLTPREYIPMIKSIVH---------------GLKFLHQNK-IIHGDLKPANVLLNEWNR
     . . ..|.| .|  || .|.             .  ..| .| . ..| |.                .|..||... ||| |.|| |.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

NNLKLTDFGLSTFVN-----------QGPFFRDYQ-----------------------TLYYKAPEVFCQGK---------VSVEIDIWSLGCVAAEIVR
  .|..|||||....           .. .    .                       |..|.|||..  .|          . ..||||||..  | . 
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GTPLFVGDNYFDQFALIQEFFGKPSRKLFNTWGGIHQFYTEYFFPRHCFEWLNPFNGDRTMEIEPHYKLAHPSRKPPLTSSLVSKLPGGNQKFLA-----
| | |                                                                                     |. .      
GKPPF------------------------------------------------------------------------------------QQQIKQCKIDF

---------------------------RFLMR----CFEWDPTERIK-SSFILNHPFF
                            .. .    ... || .||   . |||||.|
PCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase C36B7.1.AA CAMK 136-341 16 5.4e-37 116.22 In-house 1-361 (425) Show / Hide 
Range on Protein: 136-341
Range on HMM: 1-361/425
Sequence Identity: 16% (58 aa)

VLSSGYYAQVFRCTDKKTD------------KKVCIKLKNR--------------------------------NLSTTYEETIILLRIHQLNR-QNNSNC
.| .| ...|..|..|.|             .|| ||  ..                                ..   . |  |. .......  .  | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRMLDYDH------------FRGH--------HFIVL---ENYQT-----DLASYLCGRSK---------------LTPREYIPMIKSIVHGLKFLHQNK
......              .  .         ..|.   |  .      || .|.. ...               .| ||   ... |. .....|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHGDLKPANVLLNEWNR---------------NNLKLTDFGLSTFVNQG-------------------------PFFRDYQTLYYKA-PEVFCQ-----
|.| |||| |.||.. |.               ||.|..|||.......|                         ..     |..| | |||. .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------GKVSVEIDIWSLGCVAAEIVRGTPLFVGD-------------NYFDQFALIQE
           .. ..|.||.|..    . |.| | ||             |. . |  |..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMK
Kinase C36B7.1.AA CDK 196-443 22 3e-35 110.1 In-house 73-284 (284) Show / Hide 
Range on Protein: 196-443
Range on HMM: 73-284/284
Sequence Identity: 22% (65 aa)

YDHFRGHH-------------FIVLENYQTDLASYLCGRSKLTPREYIPMIKSIVH----GLKFLHQNKIIHGDLKPANVLLNEWNRNN---LKLTDFGL
.| . ...             ..| |   .||..|.              ||.. .    || ..|.|.|.| ||||.| |.|.   .    ||..||||
HDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGL

STFVN-----QGPFFRDYQ----TLYYKAPEV-FCQGKVS--VEIDIWSLGCVAAEIVR---GTPLFVGDNYFDQFALIQEFFGKPSRKLFNTWGGIHQF
.   .     . .  | |     || | |||. . . . |   .||.||.||. ||...   . ||| ||.  ||  .| ...| |. .   .| |. ..
ARAFGIPHQMS-EPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTED---NWPGVTKL

YTEYFFPRHCFEWLNPFNGDRTMEIEPHYKLAHPSRKPPLTSSLVSKLPGGNQKFLARFLMRCFEWDPTERIKSSFILNHPFF
                                                          .|....  ||. ||...  |.||.|
PDY------------------------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase C36B7.1.AA Pkinase 131-341 27 5.5e-33 117.71 Pfam 1-229 (293) Show / Hide 
Range on Protein: 131-341
Range on HMM: 1-229/293
Sequence Identity: 27% (65 aa)

YSIDEVLSSGYYAQVFRCTDKKTDKKVCIKLKNRNLSTTYEETIILLR---IHQLNRQNNSNCVRMLDYDHFRGHHFIVLENYQT-----DLASYLC--G
| | ... || ...|..|..|.| |.|..|  ..  ..  .. ....|   |. ..| |  | ||..|. . ..|  .|.|  .      ||..|.    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

RSKL--TPREYIPMIKSIVHGLKFLHQNKIIHGDLKPANVLLNEWNRNNL----KLTDFGLSTF--VNQGPFFRDYQ-TLYYKAPEVFC-QGKVSVEIDI
. ..  ...| . ... |. ||...|...||| ||||.|.|..  |....    |..||||. .     .. . ..  |..| ||||   . . . ..|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGCVAAEIVRGTPLFVGD----NYFDQFALIQE
||.||. .| . | |.| |.    |  || ..|..
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICR
Kinase C36B7.1.AA ULK 131-316 24 5.9e-29 98.26 In-house 1-245 (329) Show / Hide 
Range on Protein: 131-316
Range on HMM: 1-245/329
Sequence Identity: 24% (59 aa)

YSIDEVLSSGYYAQVFRCTDKKT----DKKVCIKLKNRN-LSTTYEE-----TIILLR-----IHQLNRQN-----NSNCVRMLDYDHFRGH--HFIVLE
|.....| .| ...|.. ..|||    ..|| .|   .. ..  . |      . ||.     ...|...|     . |.|...|.     |  ..|..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

NYQT-DLASYLC----------GRSKLTPREYIPMIKSIVHGLKFLHQNKIIHGDLKPANVLLNEWNRNN----------LKLTDFGLSTFVNQG----P
  .  || .|.              .|.  | |  .| |. |.|.||...||| |.||.|.|... .  .          ||..|||.. .|. .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

FFRDYQ-------TLYYKAPEVFC----QGKVS-VEIDIWSLGCV
 .  .        | .| ||...     | . .  . |||||||.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCI
Kinase C36B7.1.AA ULK 131-316 23 4.7e-26 89.46 In-house 1-241 (324) Show / Hide 
Range on Protein: 131-316
Range on HMM: 1-241/324
Sequence Identity: 23% (56 aa)

YSIDEVLSSGYYA-QVFRCTDKKT---DKKVCI------KLKNRNLS--------TTYEETIILLRIHQLNRQNNSNCVRMLDYDHFRGH--HFIVLENY
|.....| .| .. .|.. ..|||   ...| .      |... ..             |  |.  .. |. .|. ..|...|.     |  ..|..|  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

QT-DLASYLC---------GRSKLTPREYIPMIKSIVHGLKFLHQNKIIHGDLKPANVLLNEWNRNN----------LKLTDFGLSTFVNQG----PFFR
.  || .|.             .|.  | |  .| |. |.|.||...||| |.||.| |... .  .          ||..|||.. .|. .      . 
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

DYQ-------TLYYKAPEVFC----QGKVS-VEIDIWSLGCV
 .        | .| ||...     | . .  . |||||||.
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCI
Kinase C36B7.1.AA STE 232-325 30 1.1e-25 87.79 In-house 156-266 (359) Show / Hide 
Range on Protein: 232-325
Range on HMM: 156-266/359
Sequence Identity: 30% (36 aa)

MIKSIVHG-LKFLHQNKIIHGDLKPANVLLNEWNRNNLKLTDFGLSTFVNQ-----------------GPFF-RDYQTLYYKAPEVFCQ------GKVSV
....|..| |..||...||| |.||||.||        ||.|||... ...                 .     .  |  . ||||  |      .. ..
ICRQILKGLLYYLHSHHIIHRDIKPANILL-------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDT

EIDIWSLGCVAAEIVRGTP
  |||||||.. | . | |
KCDIWSLGCTIIEMATGKP
Kinase C36B7.1.AA TyrKc 131-443 16 1.8e-08 -85.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 131-443
Range on HMM: 1-280/280
Sequence Identity: 16% (58 aa)

YSIDEVLSSGYYAQVFRCTDKKTDKKVCIKLKNRNLSTTYEETIILLR--IHQLNRQ--NNSNCVRMLDYDHFR-------GHHFIVLENYQT-DLASYL
 . ...| .| . .|...| |    .| .|  . .        .  ..  .  . .   .. | ||.. .           . ..||.|     || .||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

CGRSK-LTPREYIPMIKSIVHGLKFLHQNKIIHGDLKPANVLLNEWNRNNLKLTDFGLSTFVNQG-------PFFR------DY--QTLYYKAPEVFCQG
  . . |.... . .   |  |  .||....|| ||   |.|..| .    | .||||| ..  .          |            .   |||..  |
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

KVSVEIDIWSLGCVAAEIV-RGTPLFVG-----DNYFDQFALIQEFFGKPSRKL----FNTWGGIHQFYTEYFFPRHCFEWLNPFNGDRTMEIEPHYKLA
| . . |.|| | .  ||  .| .   |      . .. ...... .  |  .                                               
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------------------

HPSRKPPLTSSLVSKLPGGNQKFLARFLMRCFEWDPTERIKSSFILNHPFF
             .  ..  ..       .| . || .|   | |  | .|
-------------F--VCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase C36B7.1.AA STE 419-443 37 9.1e-05 12.91 In-house 333-359 (359) Show / Hide 
Range on Protein: 419-443
Range on HMM: 333-359/359
Sequence Identity: 37% (10 aa)

FLMRCFEWDPTERIKSSFILN--HPFF
|. .|.. || .| ..|  |.  |||.
FINKCLQKDPNKRPTASQLLKSEHPFI
Kinase C36B7.1.AA CDK 131-160 28 0.00011 10.73 In-house 1-35 (284) Show / Hide 
Range on Protein: 131-160
Range on HMM: 1-35/284
Sequence Identity: 28% (10 aa)

YSIDEVLSSGYYAQVFRCTDKKTD-----KKVCIK
| . | .  | |..|... ||.|.     . | .|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALK
Kinase C36B7.1.AA Pkinase_Tyr 239-276 39 0.000183 15.74 Pfam 123-158 (270) Show / Hide 
Range on Protein: 239-276
Range on HMM: 123-158/270
Sequence Identity: 39% (15 aa)

GLKFLHQNKIIHGDLKPANVLLNEWNRNNLKLTDFGLS
|. .|.....|| ||   |.|..|   |  | .||||.
GMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLA
Kinase C36B7.1.AA STE 131-160 15 0.000376 10.7 In-house 1-45 (359) Show / Hide 
Range on Protein: 131-160
Range on HMM: 1-45/359
Sequence Identity: 15% (7 aa)

YSIDEVLSSGYYAQVFRCTDKK---------------TDKKVCIK
. . |.. .| . .|... ..|               | . . ||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIK
Kinase C36B7.1.AA CAMK 419-443 28 0.001612 6.41 In-house 401-425 (425) Show / Hide 
Range on Protein: 419-443
Range on HMM: 401-425/425
Sequence Identity: 28% (7 aa)

FLMRCFEWDPTERIKSSFILNHPFF
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LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase C36B7.1.AA ULK 419-443 32 0.009233 5.57 In-house 305-329 (329) Show / Hide 
Range on Protein: 419-443
Range on HMM: 305-329/329
Sequence Identity: 32% (8 aa)

FLMRCFEWDPTERIKSSFILNHPFF
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LIRRMLQYDEKDRISWEELFNHPWF
Kinase C36B7.1.AA ULK 419-443 36 0.011037 5.42 In-house 300-324 (324) Show / Hide 
Range on Protein: 419-443
Range on HMM: 300-324/324
Sequence Identity: 36% (9 aa)

FLMRCFEWDPTERIKSSFILNHPFF
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LIRRMLQYDEKDRISWEEIFNHPWF
Kinase C36B7.1.AA Pkinase 419-443 40 0.017759 9.84 Pfam 269-293 (293) Show / Hide 
Range on Protein: 419-443
Range on HMM: 269-293/293
Sequence Identity: 40% (10 aa)

FLMRCFEWDPTERIKSSFILNHPFF
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FIKWCLCKDPKKRPTAEQILQHPWF