Gene C36B7.2 (Nematode worm)

C36B7.2

Species: Nematode worm
Alias: CE04173, C36B7.2, aSWK176
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 7108615-7112192, WormBase Genetic Map location: X:-2.04,

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK2

Sequence

Name Sequence Type Origin Length Description Download
C36B7.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 310 Kinase domain by global Sugen HMM Fasta, JSON
C36B7.2.AA Protein Genbank 531 None Fasta, JSON

Protein domain

Protein domains of C36B7.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C36B7.2.AA DYRK2 195-504 39 1.4e-194 638.59 In-house 1-318 (318) Show / Hide 
Range on Protein: 195-504
Range on HMM: 1-318/318
Sequence Identity: 39% (127 aa)

YTIDKVIGQGCYGVVGEATDGKTKQKVAIRMV---SKLAPRIYRETEMIMYISSIDPDHTFDCVRMLDYNVFRGFHYVVTDLFDTSVKKYIKEHHPNGIA
|.|..|||.|..|.|....|.||||.|||.|.   .......|.|......|...|.|.|..||.||||..||..|.....|.......|||..|..|..
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

LENVAAMGRKILKGLVFLHEHNIVHGDLKPENIMLNLANPNDVKLGDFGLSRFAKPYHDHVQCQSMFYRAPEAFVRGRYNGATDMWSFGCTVAEMVSGKI
|..|......||..|.|||..||.|.|||||||.|. .|....|..|||.|.|...|......||.||||||....|.|..|.|||||||..||...|..
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYP

FLAGDNCDDQFYLMQEVINIPPPVFFDT------FYTNYYFFSTLKEAPKHIVITDHGPIVSFIYTKAADHRKIPGATPIGSFFTKTEQKPFNNFILKVF
...|.|..|||..|.||...||..||||      |...|.|.|...|... ...|||.......|......|..||.....|.....|...|..||...|
LFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYC-TFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGCEDENFIDFIKRCF

KWMPASRITAKQALDHPFF
.|.|..|.|..|||.||..
EWDPSERMTPSQALKHPWI
Kinase C36B7.2.AA DYRK 195-504 34 1e-145 490.37 In-house 1-320 (320) Show / Hide 
Range on Protein: 195-504
Range on HMM: 1-320/320
Sequence Identity: 34% (111 aa)

YTIDKVIGQGCYGVVGEATDGKTKQKVAIRMVSKL---APRIYRETEMIMYISSIDPDHTFDCVRMLDYNVFRGFHYVVTDLFDTSVKKYIKEHHPNGI-
|.|...||.|..| |  ..| ||...|||... .    . ....|.....|..  |||....||.|.||...|.....|..|.... . ..|..| .|  
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

ALENVAAMGRKILKGLVFLHEH-NIVHGDLKPENIMLNLA-NPNDVKLGDFGLSRFAKPYHDHVQCQSMFYRAPEAFVRGRYNGATDMWSFGCTVAEMVS
 |..|. ....||..|.|||.. ||.|.|||||||||. . |....|. |||.| | .  . . ..||.|||||| .....|. | ||||.||..||.. 
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQ-RIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFT

GKIFLAGDNCDDQFYLMQEVINIPPPVFFDT--------FYTNYYFFSTLKEAPKHIVITDHGPIVSFIYTKAADHRKIPGATPIGSFFTKTEQKPFNNF
|.....|.|. ||.....||...||. ..|.        |... .......|..|...|||| .......||. ..|..|| ........ .... |..|
GWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC-FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDDHQFKDF

ILKVFKWMPASRITAKQALDHPFF
|.|...|.|..|||..|||.||.|
IKKCLQWDPHKRITPSQALQHPWF
Kinase C36B7.2.AA CMGC 195-504 19 6e-80 262.22 In-house 1-513 (513) Show / Hide 
Range on Protein: 195-504
Range on HMM: 1-513/513
Sequence Identity: 19% (99 aa)

YTIDKVIGQGCYGVVGEATD--------------GKTKQKVAIRMVS-----KLAP----------RIYRETEMIMYIS----------SIDPDHTFD--
|.|.|.||.| |||| ...|               .|...|||  ..       |           |..|| .. ....            |||.  .  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRD-DPDNKHHNN

CVRMLDYNVFRG-----------------FHYVVTDLFDTSVKKYIKEHHP-----NGIAL-------------ENVAAMG------RKILKGLV--FLH
.|...|. ....                   | |... |.. ..|||....     ... |             .|.  .       . ||.||   ..|
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

EHN--IVHGDLKPENIMLNLANPN------------------DVKLGDFGLSRFAKPYHDH-----------------------VQCQSMFYRAPEAFVR
 |.  |.| |||||||..|  . .                   .|..||||.|.  |..||                        . ....|||||  ..
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

GR----------YNGATDMWSFGCTVAEMVSG--------KIFLAGDNC-----------DDQFYLMQEVINIPPPVFFDT----FYTNYYFFSTLKEAP
 .          |. . ||||.||  |||. |        |..  |...            || ... .|.  |.  ....    |   . |..  .| |
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHF---N-FCKHEEEWP

KHIVITDHGPIVS---------FIYTKAADHRKIPGATPIGSFFTKTEQKPFNN----------------------------------------FILKVF
..|   .. .  .         ... .|  ......  |   . . ....|...                                        .. | .
NMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKML

KWMPASRITAKQALDHPFF
.. |. ||||.|||.||.|
QYDPDKRITAEQALQHPYF
Kinase C36B7.2.AA S_TKc 195-504 22 1.4e-67 231.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 195-504
Range on HMM: 1-231/231
Sequence Identity: 22% (74 aa)

YTIDKVIGQGCYGVVGEATDGKTKQKVAIRMVSKLAPRIYRETEMIMYISSIDPDHTFDCVRMLDYNVFRGFHYVVTDLFDT---SVKKYIKEHHPNG--
|.| ..||.| .|.|  ... ||...||| ...    .|.|| .. .        |    |...|. .  .. |.|... |.   ....|||.. ..|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--IALENVAAMGRKILKGLVFLHEHNIVHGDLKPENIMLNLANPNDVKLGDFGLSRFAKPYHDHVQCQSMFYRAPEAFVRGRYNG-ATDMWSFGCTVAEM
  .    .. . . |...| ..|.|.|.| |||||||.|.      .|..||||.|.      . .| . .|.||| .    |.. . |.||.||...||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VSGKIFLAGDNCDDQFYLMQEVINIPPPVFFDTFYTNYYFFSTLKEAPKHIVITDHGPIVSFIYTKAADHRKIPGATPIGSFFTKTEQKPFNNFILKVFK
..|.          | ..| ..|                                                                 ... .|| | ..
LCGYPPFP------QMQMMFKKIG---------------------------------------------------------------SPEAKDFIRKCLQ

WMPASRITAKQALD-------HPFF
. |. |.|| .||        ||.|
KDPEKRPTA-EALQDEWDIKCHPWF
Kinase C36B7.2.AA Pkinase 302-504 26 5.2e-36 128.42 Pfam 117-293 (293) Show / Hide 
Range on Protein: 302-504
Range on HMM: 117-293/293
Sequence Identity: 26% (56 aa)

ILKGLVFLHEHNIVHGDLKPENIMLNLANPND---VKLGDFGLSRF--AKPYHDHVQCQSMFYRAPEAFV-RGRYNGATDMWSFGCTVAEMVSGKIFLAG
||.|| ..|...|.| |||||||...  |..    ||..||||...    ... .. | . .|.|||    .  |  . ||||.||...||..|.    |
ILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPG

D----NCDDQFYLMQEVINIPPPVFFDTFYTNYYFFSTLKEAPKHIVITDHGPIVSFIYTKAADHRKIPGATPIGSFFTKTEQKPFNNFILKVFKWMPAS
.    | .|| ......   |..  ... ....||| .     .                            .  ..| .   ...  || . ... |..
HCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------------------------F-HWTF-HNWSEECKDFIKWCLCKDPKK

RITAKQALDHPFF
|.||.|.| ||.|
RPTAEQILQHPWF
Kinase C36B7.2.AA STE 195-504 17 3.1e-33 114.73 In-house 1-359 (359) Show / Hide 
Range on Protein: 195-504
Range on HMM: 1-359/359
Sequence Identity: 17% (76 aa)

YTIDKVIGQGCYGVVGEATDG------KTKQK---------VAIRMVS---------------------KLAPRIYRETEMIMYISSIDPDHTFDC---V
... ..||.| .|.|  | .       ||...         .||  ..                     .   .| .| .. .  ..        .   |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNH------M-HPNIV

RMLDYNVFRG-------FHYVVTDLFD-TSVKKYIK-EHHPNG-----------IALENVAAMGRKILKG-LVFLHEHNIVHGDLKPENIMLNLANPNDV
. ... .  |         ...  . |  |. . ||  . ...           .  . .|.. | |||| | .||.|.|.| |.|| ||.|       |
KYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-------V

KLGDFGLSRFAKP------------------YHDHVQCQSMFYRAPEAFVRGR------YNGATDMWSFGCTVAEMVSGKIFLAG-DNCDDQFYLMQE--
|| |||..    .                   .    . .  . |||   ...      |.   |.||.|||. ||. ||  ..   .    |. ...  
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

---------VINIPPPVFFD---------------TFYTNYYFFSTLKEAPKHIVITDHGPIVSFIYTKAADHRKIPGATPIGSFFTKTEQKPFNNFILK
         ..| ||| . |               |                                                  ..   ..|..|| |
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTT-------------------------------------------------YPHKWSPEFKDFINK

VFKWMPASRITAKQALD--HPFF
 ..  |  | ||.| |   |||.
CLQKDPNKRPTASQLLKSEHPFI
Kinase C36B7.2.AA DYRK1 195-418 30 1.8e-31 107.45 In-house 1-228 (321) Show / Hide 
Range on Protein: 195-418
Range on HMM: 1-228/321
Sequence Identity: 30% (69 aa)

YTIDKVIGQGCYGVVGEATDGKTKQKVAIRMVSKLAPRIYR---ETEMIMYISSIDPDHTFDCVRMLDYNVFRGFHYVVTDLFDTSVKKYIKEHHPNGIA
| ||  ||.| .| |  | | .... |||...    | .     |  ..  .   |... .  |..    .||    .|..|    .   ..  |  |..
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

LENVAAMGRKILKGLVFLH--EHNIVHGDLKPENIMLNLANPNDVKLGDFGLSRFAKPYHDHVQCQSMFYRAPEAFVRGRYNGATDMWSFGCTVAEMVSG
|  .  . ..... |.|.   | .|.| |||||||.|  .    .|. ||| |  .     .   || |||.||  .  .|. | |||| || . ||  |
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQY-IQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTG

KIFLAGDNCDDQFYLMQEVINIPPPVFFD
    .| |  ||.  . ||...||  . |
EPLFSGSNEVDQMNKIVEVLGMPPKHMID
Kinase C36B7.2.AA CAMK 200-390 18 4.7e-28 86.91 In-house 1-331 (425) Show / Hide 
Range on Protein: 200-390
Range on HMM: 1-331/425
Sequence Identity: 18% (63 aa)

VIGQGCYGVVGEATDGKTK------------QKVAIRMVSK--------------------------------LAPRIYRETEMIMYISSIDP--DHTFD
..|.| .|.| .... .|.            ||||| ...|                                   ...|| |. . ...|.   ||   
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN-

CVRMLDYNVFRGF-------------------HYVVT---------DLFDTSVKKYIKEHHPNG-------------IALENVAAMGRKILKGLVFLHEH
 ......   . .                    | |.         .|||  .  ||.|| ..|             .  . .. . | |. .. ..|.|
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFD-DLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

NIVHGDLKPENIMLNLANP---------------NDVKLGDFGLSRFAKPYHDHV-------------------------QCQSMFYRA-PEAFVRGR--
|||| |||||||.|.  |.               |..|. |||.... .| ..                           .| .  | | || . . .  
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

------------YNGATDMWSFGCTVAEMVSGK
            |. ..|||| |.    |..|.
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGY
Kinase C36B7.2.AA CDC2 268-396 35 2e-25 74.63 In-house 76-212 (301) Show / Hide 
Range on Protein: 268-396
Range on HMM: 76-212/301
Sequence Identity: 35% (49 aa)

YVVTDLFDTSVKKYIK-EHHP-NGIALENVAAMGRKILKGLVFLHEHNIVHGDLKPENIMLNLA-NPNDVKLGDFGLSR-FAKPYHDHV---QCQSMFYR
| |..  |   ||| . .  .   . ...|     .||.|. |.| . |.| |||| || .. . |   .|..||||.| |  |              ||
YMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN---IKIADFGLARAFGIPIRTYTTEHEVVTLWYR

APEAFVRG-RYNGATDMWSFGCTVAEM---VSGKIFLAGD
|||   .  ||. . ||||.||. |||   |. | . .||
APEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGD
Kinase C36B7.2.AA CDK 279-401 30 2e-23 71.65 In-house 105-233 (284) Show / Hide 
Range on Protein: 279-401
Range on HMM: 105-233/284
Sequence Identity: 30% (43 aa)

KKYIKEHHPNGIALENVAAMGRKILKGLVFLHEHNIVHGDLKPENIMLNLANPND---VKLGDFGLSRFAKPYHD---HVQCQS-----MFYRAPEAFV-
|||..           .  . . .|.|| ..|...|.| |||| ||..|    ..   .|..||||.|     |.    ... .     . |||||    
KKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLG

RGRYN--GATDMWSFGCTVAEMVS---GKIFLAGDNCDDQ
  .|.   . ||||.||  |||.    .| .. ||.  ||
SKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQ
Kinase C36B7.2.AA Ciliate-E2 272-390 23 1.3e-22 74.41 In-house 120-293 (365) Show / Hide 
Range on Protein: 272-390
Range on HMM: 120-293/365
Sequence Identity: 23% (42 aa)

DLFDTSVKKYIKEHHP----NGIALENVAAMGRKILK---------------GLVFLHEHN-IVHGDLKPENIMLNLANPNDVKLGDFGLSRF-------
||||   ....|..|     . . .. .. . ..||.               .| .||. | |.| |.|||||..       .|. |||||..       
DLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-------IKIIDFGLSKKYDDDNQN

------AKPYHDHV---------------------QCQSMFYRAPEAFVRGR---------YNGATDMWSFGCTVAEMVSGK
      .| | .                       .| .  | ||| . ..          |. . |.||.|..  ||..||
RTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK
Kinase C36B7.2.AA MAPK 302-409 37 7.1e-20 65.23 In-house 124-251 (328) Show / Hide 
Range on Protein: 302-409
Range on HMM: 124-251/328
Sequence Identity: 37% (49 aa)

ILKG--LVFLHEHNIVHGDLKPENIMLNLANPNDVKLGDFGLSRFAKP-YHDHVQ---------------CQSMFYRAPEAFVR---GRYNGATDMWSFG
||.|  | ..|  |..| ||||.|| .|     |.|..||||.| . | ||.| |                   .|||||        .|. | |||| |
ILRGLKLKYIHSANVIHRDLKPSNILVNEN--CDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVG

CTVAEMVS-GKIFLAGDNCDDQFYLMQEVI
|  |||.. .|... |..  ||. |. ||.
CIFAEMLTDRKPLFPGKDYIDQWNLIMEVL
Kinase C36B7.2.AA TyrKc 195-504 17 3.1e-11 -40.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 195-504
Range on HMM: 1-280/280
Sequence Identity: 17% (61 aa)

YTIDKVIGQGCYGVV--GEATDGKTKQKVAIRMVSKLAPR--IYRETEMIMYI-SSIDPDHTFDCVRMLDYNVFR-------GFHYVVTDLFDT-SVKKY
 | .|..| |..|.|  |...     ..||. |. . | |  ..|| .. . .      .|    ||.. . .         . ...|. . .  . |.|
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-REDFMREARIMCKLGG----HHPN-IVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IKEHHPNGIALENVAAMGRKILKGLVFLHEHNIVHGDLKPENIMLNLANPNDVKLGDFGLSRFAKPY------HDHVQC----QSM-----FYRAPEAFV
...|.|. . ..    .   | .|  .||..|..| ||   |....  .   || .||||||. . .      .|        ..         |||.. 
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

RGRYNGATDMWSFGCTVAEMVS-GKIFLAGDNC--DDQFYLMQEVINI----PPPV----FFDTFYTNYYFFSTLKEAPKHIVITDHGPIVSFIYTKAAD
 |... ..| |||| .  |. . |.    |.     . . ... | .     .||                                             
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------------------

HRKIPGATPIGSFFTKTEQKPFNNFILKVFKWMPASRITAKQALDHPFF
            |     .. ..  ...  .  |..| | ..   | .|
------------F-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase C36B7.2.AA Pkinase_Tyr 304-388 29 1.5e-09 33.01 Pfam 122-209 (270) Show / Hide 
Range on Protein: 304-388
Range on HMM: 122-209/270
Sequence Identity: 29% (27 aa)

KGLVFLHEHNIVHGDLKPENIMLNLANPNDVKLGDFGLSRFA--KPYHDHVQCQ----SMFYRAPEAFVRGRYNGATDMWSFGCTVAEMVS
||. .|...|..| ||   |....   .| || .||||.|    . |  ... .      .  |||..  |... ..| |||| .  |...
KGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFT
Kinase C36B7.2.AA MAPK 195-236 40 8e-09 26.41 In-house 1-54 (328) Show / Hide 
Range on Protein: 195-236
Range on HMM: 1-54/328
Sequence Identity: 40% (22 aa)

YTIDKVIGQGCYGVVGEATDGK------TKQKVAIRMVS------KLAPRIYRE
|.|.| |||| ||||  |.| .      ...||||  .|       .. |.|||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYRE
Kinase C36B7.2.AA CDC2 489-504 62 2.5e-08 21.14 In-house 286-301 (301) Show / Hide 
Range on Protein: 489-504
Range on HMM: 286-301/301
Sequence Identity: 62% (10 aa)

PASRITAKQALDHPFF
|. ||.||.||.||.|
PQKRISAKEALQHPYF
Kinase C36B7.2.AA CDK 489-504 62 3.7e-08 22.02 In-house 269-284 (284) Show / Hide 
Range on Protein: 489-504
Range on HMM: 269-284/284
Sequence Identity: 62% (10 aa)

PASRITAKQALDHPFF
|. ||.|.|||.||.|
PKKRISAEQALQHPYF
Kinase C36B7.2.AA Ciliate-E2 479-504 35 1.3e-07 22.21 In-house 335-365 (365) Show / Hide 
Range on Protein: 479-504
Range on HMM: 335-365/365
Sequence Identity: 35% (11 aa)

NFILK----VFKWMPASRIT-AKQALDHPFF
..| |     ..  |  ||| ..|.|.||.|
DLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase C36B7.2.AA MAPK 489-504 56 4e-06 16.75 In-house 313-328 (328) Show / Hide 
Range on Protein: 489-504
Range on HMM: 313-328/328
Sequence Identity: 56% (9 aa)

PASRITAKQALDHPFF
|  |||...|| ||.|
PDKRITVEEALQHPYF
Kinase C36B7.2.AA CAMK 489-504 43 1e-05 13.66 In-house 410-425 (425) Show / Hide 
Range on Protein: 489-504
Range on HMM: 410-425/425
Sequence Identity: 43% (7 aa)

PASRITAKQALDHPFF
|  |.|..|.|.||..
PEKRMTIEQCLNHPWM
Kinase C36B7.2.AA Ciliate-E2 195-225 35 1.7e-05 14.78 In-house 1-31 (365) Show / Hide 
Range on Protein: 195-225
Range on HMM: 1-31/365
Sequence Identity: 35% (11 aa)

YTIDKVIGQGCYGVVGEATDGKTKQKVAIRM
| . |.||||..|.| .... |.....||..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKI
Kinase C36B7.2.AA DYRK1 477-504 39 2.8e-05 13.92 In-house 294-321 (321) Show / Hide 
Range on Protein: 477-504
Range on HMM: 294-321/321
Sequence Identity: 39% (11 aa)

FNNFILKVFKWMPASRITAKQALDHPFF
|   |... .. |..|||  .|| |.||
FKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase C36B7.2.AA CDC2 195-226 40 0.000167 9.18 In-house 1-32 (301) Show / Hide 
Range on Protein: 195-226
Range on HMM: 1-32/301
Sequence Identity: 40% (13 aa)

YTIDKVIGQGCYGVVGEATDGKTKQKVAIRMV
|.  . || | ||||  . | .|.| ||. ..
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKI
Kinase C36B7.2.AA CDK 195-223 41 0.000172 10.1 In-house 1-34 (284) Show / Hide 
Range on Protein: 195-223
Range on HMM: 1-34/284
Sequence Identity: 41% (14 aa)

YTIDKVIGQGCYGVVGEATDGKTK-----QKVAI
| . . ||.| ||||  | | .|.     | ||.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVAL
Kinase C36B7.2.AA Pkinase 195-228 32 0.00065 14.92 Pfam 1-34 (293) Show / Hide 
Range on Protein: 195-228
Range on HMM: 1-34/293
Sequence Identity: 32% (11 aa)

YTIDKVIGQGCYGVVGEATDGKTKQKVAIRMVSK
|.| ..||.| .|.| .... .| ..||.  ..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKK
Kinase C36B7.2.AA Pkinase_Tyr 195-223 33 0.038619 7.87 Pfam 1-33 (270) Show / Hide 
Range on Protein: 195-223
Range on HMM: 1-33/270
Sequence Identity: 33% (11 aa)

YTIDKVIGQGCYGVV--GEAT--DGKTKQKVAI
 |..|..|.|..|.|  |...  ...||..||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAV