Gene C44H4.6 (Nematode worm)

C44H4.6

Species: Nematode worm
Alias: C44H4.6, CE08727, aSWK184
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 14602888-14600206, WormBase Genetic Map location: X:18,

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
C44H4.6.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 281 Kinase domain by global Sugen HMM Fasta, JSON
C44H4.6.AA Protein Genbank 367 None Fasta, JSON

Protein domain

Protein domains of C44H4.6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C44H4.6.AA GSK 37-317 42 2.9e-187 577.62 In-house 1-328 (328) Show / Hide 
Range on Protein: 37-317
Range on HMM: 1-328/328
Sequence Identity: 42% (140 aa)

FTNLQLIGTGSFGAVYKAVLR----ENDEP----IAIKKIKVDDRFK-SRELTIMHEM---DHPNIIRLLYYYVMQQEN------CLN-FVMEFMPKDLA
... ..||.|||| ||.|...    |..|     .||||.  |.|.| .||| ||...   |||||.||.|.. |..|.      ..| .|||.||..|.
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

YVHRQFAHNDKQMPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEK--NEPNITYICSRYYRAPELIFGSKNYDTSI
.|.|....|..||| . |||||.|..||...|| |.|.||||||.|.|||...|.||||||||||.||.  |||||.|||||||||||||||..||...|
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQI

DTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKEDMAKWNYEYVHIPYD-----TITGVGIQK-------------------FIGRKLSLS--
|.||.|.|..|.|.. |.|  ||.||.| ..||..|||.||.. ..|..| .. ..     .|..  .||                   .. .. . .  
DVWSCGCVMAEMLKGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTDMQD

TLELLNSLMKMDPKLRIKPYEALTLPYF
...|.......||| |..|.||.. |.|
WIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase C44H4.6.AA CMGC 37-317 18 3.9e-102 336.49 In-house 1-513 (513) Show / Hide 
Range on Protein: 37-317
Range on HMM: 1-513/513
Sequence Identity: 18% (98 aa)

FTNLQLIGTGSFGAVYKAVL--------------RENDEPIAIKKIKVDDRFKS----------------RELTIMHEM-----------------DHPN
..... || |..| |||..               .|..| .|||||| .  ..                 ||. |. ..                 .|.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIRLLYYYVMQQ---------------ENCLNFVMEFMPKDLAYVHRQFA------------------------HNDKQMPAYSIKLYMFQLLRGIG--F
|..|.....  .               .|.|..|.|.|..||. . ..                          || | ..   |. ||.|.|||.   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LHLHN--IVHRDIKPKNLLVDESN-------------------GILKICDFGSAKRLEKN----------------------EPNITYICSRYYRAPELI
.| |.  |.|||.|| |.|... .                   |.|||||||.|. ....                      .|. .|...|.|||||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

FGSKNYD---------TSIDTWSVGTVVGELLHN--------SPIFLADSA-----------VDILALQIKAFGTPS---------------KEDMAKWN
.|.|.|.         |.|| |||| . .|.. .         |.|  .|            .| |.. .| .|||.               .|.. ...
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

YEYVHIP---------------------------YDTITGVGIQKFIGR----------------------------------KLSLSTLELLNSLMKMD
  . ...                           . .. .  ..... .                                  ...   ..||. ....|
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PKLRIKPYEALTLPYF
|. ||.. .||  |||
PDKRITAEQALQHPYF
Kinase C44H4.6.AA S_TKc 37-317 25 3.2e-78 267.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 37-317
Range on HMM: 1-231/231
Sequence Identity: 25% (76 aa)

FTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKSRELTIMHEMDHPNIIRLLYYYVMQQENCLNFVMEFMPK---DLAYVHRQFAH--NDKQMP
.. |..|| |.|| |||.. .. ..  |||.||   .   ||. |... .||||..|.....    ..| .|||...    ||  . ..  .  .....|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

AYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNITYICSRYYRAPELIFGSKNYDT-SIDTWSVGTVVGELLHN
   .. || |..... ..| |.|.|||.|| |.|.||    .||||||.|..|       |.. ...|.|||..     |.. ..| ||.| .. |.|  
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCG

SPIFLADSAVDILALQIKAFGTPSKEDMAKWNYEYVHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKMDPKLRIKPYEALT-------LPYF
 | |     .. .  .|.                                      | . ..... ....||. |.   |||.        |.|
YPPFP---QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase C44H4.6.AA CDK 37-317 29 1.7e-74 237.71 In-house 1-284 (284) Show / Hide 
Range on Protein: 37-317
Range on HMM: 1-284/284
Sequence Identity: 29% (98 aa)

FTNLQLIGTGSFGAVYKAVLREND-----EPIAIKKIKVD--------DRFKS---RELTIMHEMDHPNIIRLLYYYVMQQ---------ENCLNFVMEF
.  |. || |..| ||||  ....     . .|.|||...        . | .   || ... |. ||||..|.  ..  .         || | .|.|.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MPKDLAYVHRQFAHNDKQMPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGI-----LKICDFGSAKRLEK------NEPNIT-YICSRYY
|. ||. . .             || ||.|||||. ..| ..|.|||.|| |.|... ||.     ||| ||| |.          .    |  .  . |
MDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINN-NGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWY

RAPELIFGSKNYD--TSIDTWSVGTVVGELLH---NSPIFLADSAVDILALQIKAFGTPSKE------DMAKWNYEYVHIPYDTITGVGIQKFIGRKLSL
||||| .|||.|.  |.|| |||| . .|..    . |.|  ||  | | . .. .|||. .      ..  .                           
RAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------

STLELLNSLMKMDPKLRIKPYEALTLPYF
   .|||... .||| ||.  .||  |||
---DLLNKMLCYDPKKRISAEQALQHPYF
Kinase C44H4.6.AA Pkinase 37-317 27 8.1e-69 239.73 Pfam 1-293 (293) Show / Hide 
Range on Protein: 37-317
Range on HMM: 1-293/293
Sequence Identity: 27% (85 aa)

FTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKSR--------ELTIMHEMDHPNIIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQF----A
.. .. || |||| |||.. . . .  |.|.||.... ..         |. ||....||||.||....   .. .  .|||.....|  |   |    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY--MVMEYCEGGLY-VMDLFDYIST

HNDKQM--PAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGIL----KICDFGSAKR--LEKNEPNITYICSRYYRAPELIFGSKNYDTSID
.... .  .   .| || |.|||. ..| ..|.|||.|| |.|.| .|| .    ||||||.||   . .|. . |. ....|.|||.| |.. |....|
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

TWSVGTVVGELLHNSPIFLAD----SAVDILALQIKAFGTPSKEDMAKW----NYEYVHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKMDPKLRIKP
 ||.| .. |.|   |.|  .    . .| ...  .  |.| ..|  .|    ... . . . .     . ..   ..| . ....... ..||| |. .
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----FHWTF-HNWSEECKDFIKWCLCKDPKKRPTA

YEALTLPYF
 ..|  |.|
EQILQHPWF
Kinase C44H4.6.AA CDK7 37-257 37 2.7e-64 169.95 In-house 1-226 (288) Show / Hide 
Range on Protein: 37-257
Range on HMM: 1-226/288
Sequence Identity: 37% (90 aa)

FTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIK---VDDRFKS-------RELTIMHEMDHPNIIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHN
.. ...|| | |. ||||   . .. .||||||     . .|        ||  |  || |.|.| |.   .. .   .. |..||. ||  | .     
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLI--DIFMHKSNIQLVFDFMDWDLEVVIK-----

DKQ---MPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNITY---ICSRYYRAPELIFGSKNYDTSIDTWSV
||.   .||  || || ..|.|. ..|.. | |||.|| |||..| ||.||| ||| |.      ||  |   .  |.|||||| || . | |..| |||
DKSIILTPA-HIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNE-NGQLKIADFGLARFY--GSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSV

GTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKED
| .  ||.   |..  || .| |    .. |||. |.
GCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEE
Kinase C44H4.6.AA CDC2 37-241 32 5.4e-62 189.09 In-house 1-216 (301) Show / Hide 
Range on Protein: 37-241
Range on HMM: 1-216/301
Sequence Identity: 32% (72 aa)

FTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKS--------RELTIMHEMD-HPNIIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHND
.. .. || |..| |||.  .. .. .|.|||...             ||. .. |.. ||||..|   ..    | |  | |..  || .  ..    .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

KQMPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNIT---YICSRYYRAPELIFGSKNYDTSIDTWSVGTVV
|.||   .| ||.|.|.|. |.| . |.|||.|| |.|.|. .| .|| ||| |.    .  ..|    .  . |||||. .|.| |.|..| ||.| . 
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDK-KGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIF

GEL---LHNSPIFLADSAVD
 |.    .. |.| .||  |
AEMFMDVTKKPLFHGDSEID
Kinase C44H4.6.AA CAMK 42-221 19 1.9e-51 163.63 In-house 1-321 (425) Show / Hide 
Range on Protein: 42-221
Range on HMM: 1-321/425
Sequence Identity: 19% (62 aa)

LIGTGSFGAVYKAVLREND------------EPIAIKKIKV--------------------------------DDRFKSRELTIMHE-------MDHPNI
 .|.|||| |.... ...             .  ||| |.                                 | ..  ||. ||         .|||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLLYYYVMQQ-----------------ENCLNFVM---EFMPKD------LAYVHRQ-----------FAHNDKQMPAYSIKLYMFQLLRGIGFLHLHN
|.|. .|   .                 .... .||   |...        . |. ..           .. ... ..    . |. |.. .. ..| ||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKPKNLLVDESN----------------GILKICDFGSAKRLEKNEPNI------------------------TYICSRYYRA-PELIFG-----
|||||.|| |.|.|..|                . .||.||| |......| |                         |.  . .| | ||.. |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------SKNYDTSIDTWSVG
         . |. ..| ||.|
MQNATDEEKPYYGPKCDMWSCG
Kinase C44H4.6.AA RCK 37-317 30 2.1e-51 161.21 In-house 1-298 (298) Show / Hide 
Range on Protein: 37-317
Range on HMM: 1-298/298
Sequence Identity: 30% (92 aa)

FTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKS-------RELTIMHEMD-HPNIIRLLYYYVMQQEN--CLNFVMEFMPKDLAYVHRQFAHN
 . .  .| |..| | ||.  |. | .|||| |   .|.|       ||.. .  .  ||||| |.   | ....   | ||.|.| ..|    . |.  
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK--QKFYSWEECMNLREIKSLRKLNPHPNIIKLK--EVIRDNDTYQLYFVFEYMDMNLYQMMKDFKER

DKQMPAYS--IKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDES--------NGILKICDFGSAKRLEKNEPNITYICSRYYRAPELIFGSKNYDTSID
.| .|     || .|.|.| |. ..| |.. |||.|| |... .|        ....||.|||...  . . |.  |. .|.|||||..  . .|.. .|
RKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMD

TWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKEDMAKWN--YEYVHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKMDPKLRIKPYEALTL
 |.|| .  || .  | |   | .| .   .|  |||.|.|  .     . ... .    |..... | . .|  ..||.. ... ||. || ...||  
IWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPN-CSQDCIELMEKMLQWDPQKRITAQQALQH

PYF
|||
PYF
Kinase C44H4.6.AA Ciliate-E2 37-317 19 2.5e-49 167.48 In-house 1-365 (365) Show / Hide 
Range on Protein: 37-317
Range on HMM: 1-365/365
Sequence Identity: 19% (79 aa)

FTNLQLIGTGSFGAVYKAVLRENDE-----------------------PIAIKKI-KVDDRFKSRELTIMHEMD----------------HPNIIRLLYY
.  ...||.|.|| |||.  .....                        .|.| . | . .....|. || |..                |||||.. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YVMQQENCLNFVMEFMPK-DLAYVHRQFAHNDKQMPA-------YSIKLYMFQLLRGI-------------GFLHLHN---IVHRDIKPKNLLVDESNGI
. ....|.. .|||.    || .  ... .. .. .        . || .| |.|.|.             .. .||.   |.|||||| |.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

LKICDFGSAKRLEKNEPNITY--------------------------------ICSRYYRAPELIFGSKN--------YDTSIDTWSVGTVVGELLHNSP
.||.||| .|.. ... |.|.                                ... .| ||| . | |.        ||...| ||.| .  |.| . |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

IFLADSAVDILALQIKAFGTPSKEDMAKWNYEYVHIPYDTITGVGIQKF----------------IGRKLSLSTLELLNS----LMKMDPKLRIK-PYEA
 |                                   .. |    |. .                .  |.|...  |..     ... ||. ||  . ..
PF-----------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI

LTLPYF
|  |.|
LNHPWF
Kinase C44H4.6.AA ERK7 37-317 29 2.2e-47 159.93 In-house 1-292 (292) Show / Hide 
Range on Protein: 37-317
Range on HMM: 1-292/292
Sequence Identity: 29% (89 aa)

FTNLQLIGTGSFGAVYKAVLRENDEPIAIKKI------KVDDRFKSRELTIMHEMD-HPNIIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHNDKQ
.  .. .| | .| | ||. .   . .|.|||      ..|     || ....|.. |||||||.     . .  .  | |||  ||  | |.     . 
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRK----GNI

MPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNE------PNIT-YICSRYYRAPELIFGSKNYDTSIDTWSVGT
.     .  |.|||| | ..|  |..|||.|| |.|.| |.  .|.|||| |  . . |      | .| |.  | |||||   ||..|   .| ||.| 
LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLD-SECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGC

VVGELLHNSPIFLADSAVDILALQIKAFGTPSKEDMAKWNYEYVHIPYDTITGVGIQKF--IGRKLSLSTLELLNSLMKMDPKLRIKPYEALTLPYF
..||.| . |.|   | .. . . ..  . |..||..  . .|     . .     ...  . .. .   ..||  |. . || |.   .||  || 
ILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase C44H4.6.AA CDK5 37-181 37 4.7e-37 114.29 In-house 1-145 (287) Show / Hide 
Range on Protein: 37-181
Range on HMM: 1-145/287
Sequence Identity: 37% (56 aa)

FTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDR------FKSRELTIMHEMDHPNIIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHNDKQM
.  .  || | .| ||||  .|  | .|.|... |.          ||  .. |. |.||.||  . |.  |. |  | ||. .||     ..     .|
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRL--HDVIHSEKKLTLVFEFCDQDLKKYMDSCNG---EM

PAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSA
 .  || .|.|||.|..| | |.. ||| || |||.   ||.||  ||| |
DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINK-NGELKLADFGLA
Kinase C44H4.6.AA CDK5 199-317 32 1.9e-21 64.13 In-house 164-287 (287) Show / Hide 
Range on Protein: 199-317
Range on HMM: 164-287/287
Sequence Identity: 32% (40 aa)

YRAPELIFGSKNYDTSIDTWSVGTVVGELL-HNSPIFLADSAVDILALQIKAFGTPSKED---MAKW-NYEYVHIPYDTITGVGIQKFIGRKLSLSTLEL
||.|   .||| | |||| ||.| .  |.     | |   .  | | .  |  |||. .    ..|  .|   | .|.   .    . | .||.   ..|
YRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDL

LNSLMKMDPKLRIKPYEALTLPYF
|. .....|. ||   .||  |||
LQKMLQCNPNQRISAKAALHHPYF
Kinase C44H4.6.AA Pkinase_Tyr 37-179 30 3.6e-20 68.93 Pfam 1-156 (270) Show / Hide 
Range on Protein: 37-179
Range on HMM: 1-156/270
Sequence Identity: 30% (49 aa)

FTNLQLIGTGSFGAVYKAVLR----ENDEPIAIKKI--KVDDR------FKSRELTIMHEM-DHPNIIRLLYYYVMQQEN-CLNFVMEFMPK-DL-AYVH
 | .. .| |.|| |||....    ... | |.|..  . ...      | . |. ||... .||||.||.   . |.|   .  |||.||. ||  | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RQFAHNDKQMPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFG
..  ..... .   .  . .|  .|  .|. .|..|||.  .| ||.|.| . ||||||
KHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFG
Kinase C44H4.6.AA TyrKc 37-312 23 2.2e-12 -22.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 37-312
Range on HMM: 1-280/280
Sequence Identity: 23% (74 aa)

FTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKS--RELTIMHEM--DHPNIIRLLYYYVMQQE-----NCLNFVMEFMPKDLAYVHRQFAHND
 | .. .| | || |||....   .. |.|..| |   .   ||. ||..   .||||.||. . . |..       |  |||.||.  .  ..  .| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLRKHRP

KQMPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKN----EPNITYI-----CSR-----YYRAPELIFGSKNYDT
|  .      ...|  .|  .|| .|..|||.   | ||.| . . ||.||| .. ..      |   .|      ...        ||| |. .| . |
K-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-FTT

SIDTWSVGTVV------GELLHNSPIFLADSAVDILALQIKAFGTPSKED---MAKWNYEYVHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKM----
  | || | .       |.  .  .|.   |. .....  . .  |  ..   |.                     |        . |. . .||.    
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------F-----VCCPDEMYQ-IMKQCWHE

DPKLR-----IKPYEAL
||. |     |  .| .
DPEDRPTFSEI--HECF
Kinase C44H4.6.AA CDK7 291-317 33 2.2e-07 15.24 In-house 262-288 (288) Show / Hide 
Range on Protein: 291-317
Range on HMM: 262-288/288
Sequence Identity: 33% (9 aa)

LELLNSLMKMDPKLRIKPYEALTLPYF
|.|.  .  |.|  |..  ..|  |||
LDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase C44H4.6.AA CDC2 291-317 44 6e-07 16.82 In-house 275-301 (301) Show / Hide 
Range on Protein: 291-317
Range on HMM: 275-301/301
Sequence Identity: 44% (12 aa)

LELLNSLMKMDPKLRIKPYEALTLPYF
..||...   ||  ||.  |||  |||
IDLLMQMLQYDPQKRISAKEALQHPYF
Kinase C44H4.6.AA CAMK 293-317 24 0.017285 3.03 In-house 401-425 (425) Show / Hide 
Range on Protein: 293-317
Range on HMM: 401-425/425
Sequence Identity: 24% (6 aa)

LLNSLMKMDPKLRIKPYEALTLPYF
|...... ||. |..  ..|  | .
LIRKMLQVDPEKRMTIEQCLNHPWM