Gene cdk-1 (Nematode worm)

cdk-1

Species: Nematode worm
Alias: aSWK159, CC2_CAEEL, T05G5.3, CE00315, cdk-1, ncc-1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: III: 9742890-9744282, WormBase Genetic Map location: n/a,

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
cdk-1.AA Protein Genbank 332 None Fasta, JSON
cdk-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 291 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of cdk-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase cdk-1.AA CDC2 22-312 62 1.4e-226 704.18 In-house 1-301 (301) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-301/301
Sequence Identity: 62% (188 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEG--VPSTAVREISLLKELQ-HPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMD-QLGKDEY
..|.|||||||||||||.|...|| .||.||||||.||||  |||||.||||.||||. |||.| |. ||.| |.|...||.|..|||.||| ...|...
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYT--HEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEM
.|....|||..||||...||||||..||||||||.|.|..|.||.||||||||.|||||.||  ||||||||||||||.|..|||..|||||||||||||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---ATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKFYDKKTGKHL--LDDTAFSLLEGLLIYDPSLRLNAKKALVHP
   .||||||.||||||.||.|||.||||.| .|.||..|||||.|||.|... |.. .......|..  ||.....||. .|.|||. |..||.|| ||
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHP

YF
||
YF
Kinase cdk-1.AA CDK 22-312 47 3.1e-177 571.77 In-house 1-284 (284) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-284/284
Sequence Identity: 47% (156 aa)

FTKLEKIGEGTYGVVYKGKNRRTN-----AMVAMKKIRLES-----EDEGVPSTAVREISLLKELQHPNVVGLEAVIMQE-----------NRLFLIFEF
. |||||||||||||||.....|.      .||.||||.|.     |.||.|.||.||||||||| |||.| |  |....           |.|...||.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGA-----IKLADFGLARAIGI------PIRVYTHEVVTLWYRA
.  ||| |||             |.|..|.|... .||.....||||||||.|..|||      .|.|||||||| ||      |.|.||||||||||||
MDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRA

PEILMGAQRYS--MGVDMWSIGCIFAEMAT---KKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDT
||.|.|...||   ..||||.|||||||.|   .||||.|||||| ||.|||..|||||  | ||..||||                             
PELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------------

AFSLLEGLLIYDPSLRLNAKKALVHPYF
   ||...| |||. |..|. || ||||
--DLLNKMLCYDPKKRISAEQALQHPYF
Kinase cdk-1.AA CDK5 22-312 51 3.1e-162 516.83 In-house 1-287 (287) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-287/287
Sequence Identity: 51% (153 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLE
. |.|||||||||.|||..|. |  .||.|..||.||||||||||.|||.|||||.|.|.| |  ||  |..| |.|||.  |||.|||...   .. ..
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNG--EMDMH

TLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMA-TKKP
. ||. .| |. . |||...| ||||||||||.  ||  |||||||||| |||.| |.|||||||||.| .|||.. ||  .||||.|||||||| . .|
IIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRP

LFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYK---ATFPKWRENF-LRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF
|| | .. |.|.|||...|||.| .| ..  |||||     .|..  .  .           . || .   ||...|...|  |. ||.|| ||||
LFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIV-------PKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase cdk-1.AA CMGC 22-312 27 2.1e-143 474.59 In-house 1-513 (513) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-513/513
Sequence Identity: 27% (142 aa)

FTKLEKIGEGTYGVVYKGKN--------------RRTNAMVAMKKIRLES---------EDEGVPSTAVREISLLKELQ-----------------HPNV
.....||||||||||||...              ..|| .||.|||...          | .|.|..| |||..||.|.                 |.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VGLEAVIMQEN-----------------RLFLIFEFLSFDLKRYMDQLGKD----EYLPL-------------ETLKSYT------FQILQAMC--FCHQ
|.|  ... .|                  |.|.||..  ||..|...  .|      .||             .. |...      .|||...   .||.
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHS

RR--VIHRDLKPQNLLVDNN--------------------GAIKLADFGLARAIGIP---------------------IRVYTHEVVTLWYRAPEILMGA
..  .|||||||.|.|...|                    | .|..||||||.....                      | |||.|||.||||||||.|.
HWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGW

QRYS---------MGVDMWSIGCIFAEMATK--------KPLFQGDSE-----------IDELFRIFRVLGTPT---------------ELEWNGVESLP
..|.          ..||||.||||||| |.        ||||.|.||           || ||.||.||||||               | || .. .||
KHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLP

DYKA--------------T------------FPKWRENFLRDKFYDKKT----------------------------GKHLLDDTAFSLLEGLLIYDPSL
.|.               .            ||.|. . ....| ....                             ....|. |. ||...|.|||. 
WYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDK

RLNAKKALVHPYF
|. |. || ||||
RITAEQALQHPYF
Kinase cdk-1.AA CDK7 22-312 42 2e-135 363.3 In-house 1-288 (288) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-288/288
Sequence Identity: 42% (128 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIR----LESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEY
..|...||||....|||.    |.  || |||.     .  . |.  ||.||| .|.|.||.||.||  ..|.   . |.|.|.  ||        ||  
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVI----KDKS

LPLE--TLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEM
. |     |.|. ..|| . .||.  . |||||| |||.. || .|.|||||||..| | |.||| ||| |||||| | ||  |  ||||||.|||||| 
IILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAEL

ATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRE---NFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF
    | . |||.|| | |||. |||||| || .. ...||  .| .. .     ||. |     .  |||     |..|..  .|. |. .  .| .|||
MLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDY-IKFKDFPGYSRTPLRHIFTA--ASDDLLD-----LMCGMWTMNPCKRWTCTQCLKMPYF
Kinase cdk-1.AA PITSLRE 22-312 45 5.9e-123 414.77 In-house 1-295 (295) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-295/295
Sequence Identity: 45% (135 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLE--SEDEGVPSTAVREIS-LLKELQHPNVVGLEAVIM--QENRLFLIFEFLSFDLKRYMDQLG--K
| .| .|.||||||||..|..||.  ||.|.. .|   | || | |..|||. .|..|||||.| .  ..|    .  ....|..  |||  |.     .
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

DEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAE
.. .| |. |. . | | .. . |   ..|||||  |||  ..|  |..||||||  | ||. ||  ||||||||||.| |.. ||  |||||.||||||
QPFKPGEI-KCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAE

MATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKA-T-FPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF
. |.||||||.||||.. .||  .|||||  | |. .||  |. . ||.  .| || .|     .  .. ||.|.|| ..| |.|  |..| .|| ||.|
FITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFP----AENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase cdk-1.AA PCTAIRE 22-312 46 3.8e-115 388.83 In-house 1-291 (291) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-291/291
Sequence Identity: 46% (141 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLE
..||.| |||||  |||.. . |. .||.| |||| | || | ||.||.||||.|.| |.| |  .| ..  | |.||..  |||.|||. |    .   
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCG--NIMNMH

TLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKKPL
  | . ||.|  . .||.|.. ||||||||||..  |  ||||||||||  .| ..| ||||||||| |..|||   ||  .||| .||||.||.| .||
NVKLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPL

FQGDS------EIDELFRIFRVLGTPTELEWNGVESLPDYKA-TFPKWRENFLRDKFYDKKTGKHLLD---DTAFSLLEGLLIYDPSLRLNAKKALVHPY
| |          |.|  |||.||||.|  | ||.|......  ||..||  |        .    ||    .   ||. || | .  |. | ||. |||
FPGSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLI-------NHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPY

F
|
F
Kinase cdk-1.AA PFTAIRE 22-312 45 1.5e-108 366.9 In-house 1-287 (287) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-287/287
Sequence Identity: 45% (134 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLE
. |||| |||.|  ||||. . .. .||.| |||. ..||.| ||.|| ||||.|.| |.| |  .|  .  | ..||..  ||. |||.      .  .
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKH--PGGMHPN

TLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKKPL
  . . || |  . .|||||| ||||||||||. . |  ||||||||||  .| . | ||||||||| | .|.|.  ||  .||| .|||| || . .|.
NVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPA

FQGD-SEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRE-NFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF
| |     | | .||.|||||||  | || .|| ||   |.| .  | . |   .   . ..   |..|. ..| . |  |. |..|..||||
FPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYK---PHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase cdk-1.AA Pkinase 22-312 32 1.5e-103 355.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-293/293
Sequence Identity: 32% (99 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVR--EISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSF-----DLKRYMD--QL
.....|||.|..|.|||.... |. .||.|.|....|..... |..|  ||...|.|.|||.| |  . . .... ...|..       ||..|.   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAI----KLADFGLARAI-GIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWS
|.   .. ...|.|  |||... .||....|||||||.|.|.|||| |    |..|||||. .   . . .|. ..|.||.|||...|.| |.  |||||
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGCIFAEMATKKPLFQGD----SEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNA
.|||..||....|.|.|.    . .|....|.|..|.|.. .|    | .... ... | .          .|  |...... ......| .||. |..|
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTA

KKALVHPYF
. .| ||.|
EQILQHPWF
Kinase cdk-1.AA S_TKc 22-312 28 1.5e-100 341.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-231/231
Sequence Identity: 28% (88 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSF---DLKRYMDQLGK---D
...|.|||.|..|.|||.....|.  ||.|.|.          .. |||..||. .|||.| |  |.   ..|....|...    ||..|... |.   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

EYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSM-GVDMWSIGCIFAE
 ..|  . ..|. ||..|. .||....|||||||.|.|.|.   ||..|||||| .       |. ..|.||.|||.|     |.   .|.||.|||..|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALV------
|.. .|.|.      .....|...|                                          .. | ......| .||. |. | .||       
MLCGYPPFP------QMQMMFKKIG------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPYF
 ||.|
CHPWF
Kinase cdk-1.AA CRK7 22-312 33 9e-95 321.16 In-house 1-343 (343) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-343/343
Sequence Identity: 33% (117 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESE---DEGVPSTAVREISLLKELQHPNVVGLEAVIMQ--------ENR--LFLIFEFLSFDLKRY
. ... ||||||| ||| || .|. ||| ||.|.. |    || | ||.||| .|..|.|.|.| |  ..          . .   ...||    ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

MDQLGKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPI--RVYTHEVVTLWYRAPEILMGAQRY-------
..  .   .  .. .|..  |.|  |  ||.. ..|||.|  |.|..|.| .|.|||||||        | ||  |.|||||.|| | |..||       
LES-KEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILK

-------------------------------SMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWR--ENF
                                  .|||| |||..| .||||.|||  |.. |  |... |.|.   |  |  || ...  || |  .  
ELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPK-RQYNRR

LRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF
||  ||..|    ...  .. || ..| .||. |  |. .| |..|
LREEFYHHKK-PVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase cdk-1.AA CDK4 22-312 40 1.2e-86 294.12 In-house 1-290 (290) Show / Hide 
Range on Protein: 22-312
Range on HMM: 1-290/290
Sequence Identity: 40% (121 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDE--GVPSTAVREISLLKELQ---HPNVVGLEAV--IMQENR----LFLIFEFLSFDLKRYMD
. ..  |||| || ||.     |   || |..|  ...|  |.|   .||||... |.   |||.| |  |   |   |    . ..||    ||. |.|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

QLGKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGC
.. .   .| .| |  ..|.| .. | |  |.|||||||||.||  .| .|||||||||  .      |  ||||||||||.|  .. |   |||||.||
KCPP-PGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMAL-TPVVVTLWYRAPEVLL-QSYYNTPVDMWSVGC

IFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHP
|||||   .||| | || | | .|| | |.|.| .|    |||     ||  .   ..|   .       ..  .  ||.  | |....|. | ..| ||
IFAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLP--WDHFPQRHPRPFKDFCPH-------MCKQGDDLLQKMLCYNHHKRMSAYQCLQHP

YF
||
YF
Kinase cdk-1.AA Pkinase_Tyr 22-171 31 8.4e-29 98.17 Pfam 1-161 (270) Show / Hide 
Range on Protein: 22-171
Range on HMM: 1-161/270
Sequence Identity: 31% (53 aa)

FTKLEKIGEGTYGVVYKGKNR----RTNAMVAMKKIRLESEDEGVPSTA------VREISLLKEL-QHPNVVGLEAVIM-QENR--LFLIFEFLSF-DLK
 |...|.||| .|.||||. .     |.  || |...     ||  . .       ||....|.| .|||.| | .|.. |.    .....|.    ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

RYMDQL-GKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAI
 |  .    .. |....| .. .|| ..| . .... |||||   | ||..|. .| .||||||.|
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase cdk-1.AA TyrKc 22-271 23 3e-16 40.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-271
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKEL--QHPNVVGLEAVIMQE-------NRLFLIFEFLSF-DLKRYMDQ
 |...|.||| .|.||||. .    .|| |... ..          ||......|  .|||.| | .|..|.         |....|. .  ||| |   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LGKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIP------IRVYT-----HEV--VTLWYRAPEILMGAQR
 ...  |....| |. .|| . | . |....|||||   | ||..|. .| .||||.|.|.          .|.     ..   . .   ||| .    .
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK

YSMGVDMWSIGC----IFAEMATKKPL----FQGDSEIDELFRIFRVLGTPTELEWNGV----ESLPDYKATFPKWRE--------NFLRDKF
..   | || |     ||   ..  |     .  ..|. |. .  . .  | . .   .     .   |.     |.|        . ....|
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF