Gene cdk-7 (Nematode worm)

cdk-7

Species: Nematode worm
Alias: cdk-7, Y39G10.con155, Y39G10AL.3, CE30320, aSWK163
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: I: 2291184-2281534, WormBase Genetic Map location: I:-10.13,

Classification

Group: CMGC
Family: CDK
Subfamily: CDK7

Sequence

Name Sequence Type Origin Length Description Download
cdk-7.AA Protein Genbank 330 None Fasta, JSON
cdk-7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 285 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of cdk-7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase cdk-7.AA CDK7 5-289 67 8.60000000001e-284 766.55 In-house 1-288 (288) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-288/288
Sequence Identity: 67% (194 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIK-LGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEIILM
|..|||.||||||.||.|.|...|..||||||| ||.|.|||||||||||||||.|.|..|||.|||.|...|...|||||||||.|||.|||||.|||.
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

PAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYTHQVVTRWYRAPELLFGARSYGVGIDIWSVGCIIAELLLRN
|||||...|..|.|||..|..|||||||||||||||..|..|..|||||||.|||||.||||||||||||||||||||.||.|.|.||||||.|||.||.
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEY--MALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYF
|..||.||||||..||..||.||.|.||||..|..|...|....|  ..|...|.||..||||||.||||..|.||.||||.|.|.||
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase cdk-7.AA CDK 5-289 41 1.5e-158 510.98 In-house 1-284 (284) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-284/284
Sequence Identity: 41% (131 aa)

YDTIKHLGEGQFANVYLAQDLESG-----ECVAIKKIKLGS--REEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHR-----------TSIQLVFDF
|. .. .||| .. || |.|...|     . ||.|||.. .  |||.|.|.. ||||||.||||. |.||. |.||. .            .....||..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGR-----VKLTDFGLARFFGS------PNRNYTHQVVTRWYRAPE
||.|| ....          ||....|.| ||...| .||.||||||.|.|.|. |      .|..|||||| ||.      ||| |||.|||.||||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLFGARSYG--VGIDIWSVGCIIAELLL---RNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEYMALNYYFSAAPQDLLDLMAGMW
||.|.. |.   .||.||||||.||...   | |.|||.|.|||| |||.|.|.||...||..|..  |                        ||. .| 
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DLLNKML

TFDPIKRLTCTQSLQMEYF
..|| ||....| ||..||
CYDPKKRISAEQALQHPYF
Kinase cdk-7.AA CMGC 5-289 27 1.3e-135 448.58 In-house 1-513 (513) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-513/513
Sequence Identity: 27% (140 aa)

YDTIKHLGEGQFANVYLAQD--------------LESGECVAIKKIKLGSREE-------AKDGINRTAIREIKLLKEI-----------------HHDN
|. || .||| ...|| ..|               |..| |||||||.   .|       .|||....|.||||.||..                 || |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIGLRDVIGHRT-----------------SIQLVFDFMDTDLEHVIKDKE--------IILMPAH------------IKNIT------MQMLLGLE--FL
|..|.|.. |.                  .. |||..||.|| ..||..         . | . |            ||...       |.| ||.  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HVHW--ILHRDLKPNNLLMNKM--------------------GRVKLTDFGLARFFGSP---------------------NRNYTHQVVTRWYRAPELLF
| ||  |.|||||| |.|.|.                     ||.|. ||||||.....                     || |||.||||||||||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GA---------RSYGVGIDIWSVGCIIAELLLR--------NPIFPGESD-----------IDQLVKIFNILGCPT---------------PETWPNMTE
|.         . |. .||.||||||.||....         |.|||.|.           |||| |||..|| ||               .|.||||..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

MNSY-----------------------VII---KPQTEYMALNYYFSA-----------------------------------APQDLLDLMAGMWTFDP
.  |                       . .   .|.  .  ..  |                                     ......||. .| ..||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

IKRLTCTQSLQMEYF
 ||.|. | ||..||
DKRITAEQALQHPYF
Kinase cdk-7.AA CDC2 5-289 40 2.1e-121 375.04 In-house 1-301 (301) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-301/301
Sequence Identity: 40% (122 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIH-HDNIIGLRDVIGHRTSIQLVFDFMDTDLEHVIK-DKEI--
|  |. .||| .  || ..|..... ||.|||.| . .|   |.  |||||| .|||.  |.||. |.|||    ....||...| ||    .  .    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGD-GVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNK

ILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYT--HQVVTRWYRAPELLFGARSYGVGIDIWSVGCIIAE
 . |. .|....|.| |..|.| . |.|||||| |.| .| |..|. |||||| || | |.||  | |||.||||||.|.|.. | ...|.||.|||.||
HMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAE

L---LLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEYMALNYYFSA---------APQDLLDLMAGMWTFDPIKRLTCTQSLQM
.     . |.|.|.| |||| ||| ||| |. .|||..|..  |    |. .   |  ..           .... .||   |   ||.||..  . || 
MFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQH

EYF
 ||
PYF
Kinase cdk-7.AA CDK5 5-289 42 1.4e-109 347.48 In-house 1-287 (287) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-287/287
Sequence Identity: 42% (122 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEIILMP
|. .  .||| .. || |.. |..| ||.|...| |  |   |.  |||||| ||||. | ||. | |||     . ||| |.| ||   . . .  . .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDE---GVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDM

AHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYTHQVVTRWYRAPELLFGARSYGVGIDIWSVGCIIAELL-LRN
. || .  |.| ||.| | | .||||||| ||| || |  || |||||| || | |.|.| ||| |||.|  |.|.. |   ||.||.|||.||.     
HIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGR

PIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSY-VIIKPQTEYMALNYYFSAAPQ---DLLDLMAGMWTFDPIKRLTCTQSLQMEYF
| ||| .. ||| .|| |.| |. ..|| .|..  | . ...   | |   . .  |.    ..||. .|  ..| .|..  . |.  ||
PLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase cdk-7.AA Pkinase 5-289 30 9.5e-95 325.87 Pfam 1-293 (293) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-293/293
Sequence Identity: 30% (93 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIR--EIKLLKEIHHDNIIGLRDVIGHRTSIQLVFDFMDT-----DLEHVIK-
| ... .|.| |. ||....  .|. ||.|.||.   ...|.. ..|..|  ||...|...|.||. |.|.   ...| .|.....      || ..|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKK---RHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

DKEIIL--MPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRV----KLTDFGLARFF-GSPNRNYTHQVVTRWYRAPELLFGARSYGVGIDI
...  .   . ..|..  |.| |||..| ..|.|||||| |.|... | .    |..|||||..|   .|. .|. ..|.||.|||.. |.. ||  .|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSVGCIIAELLLRNPIFPGE----SDIDQLVKIFNILGCPTPETWPNMTE-MNSYVIIKPQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSL
||.|||..|.|...|.|||.    . .||...|..|.|.|... ||.  . .... .   . .   .     .......|.. .....|| ||.|..| |
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQIL

QMEYF
| ..|
QHPWF
Kinase cdk-7.AA S_TKc 5-289 28 1.9e-94 321.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-231/231
Sequence Identity: 28% (86 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLVFDFMDT---DLEHVIKDKEII
|. ....|.| |. ||.... ..|. ||||.||            ....|||..||. ||.||. | ||. . ... .|....|.   || ..||..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYTHQVVTRWYRAPELLFGARSYGV-GIDIWSVGCI
     . . |.. .. |....||..| |.|.|||||| |.|...  ..|..||||||..       |....|.||.|||.|    .||   .|.||.|||
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

IAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQ-------MEY
..|.| . | ||      |. ..|...|                                   .....|.. .....|| ||.|. . ||       ...
LYEMLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

F
|
F
Kinase cdk-7.AA PITSLRE 5-289 36 1.9e-93 316.75 In-house 1-295 (295) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-295/295
Sequence Identity: 36% (108 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIK-LLKEIHHDNIIGLRDVI--GHRTSIQLVFDFMDTDLEHVIKDKE--
.  .   .|| .  || |.| . .| ||.|..|.. . | |.|.  |..|||. .|... |.||. .. ..     ..| .|..... ||  ..      
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKE-KEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRR

-IILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYTHQVVTRWYRAPELLFGARSYGVGIDIWSVGCIIAE
     |  ||  . | |.| |..| .||.|||||  |||..  |  |. |||||| .||| . ||  ||| |||||||| |.. |   .|.|||||| ||
NQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAE

LLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIK--PQTEYMALNYYFS---AAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYF
...  |.|.|.|.|||. .||. .| ||   ||  ||.     ..  |.  |  |.  |       .  .||. .| |..| .|.| .. |. ..|
FITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase cdk-7.AA CRK7 5-289 34 2.8e-92 312.9 In-house 1-343 (343) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-343/343
Sequence Identity: 34% (117 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGH----------RTSIQLVFDFMDTDLEHV
|. |.  ||| .  || |.... || || ||...      |.|   |||||||.|.. .|.||. |....            . |. .||. || ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

IKDKEII-LMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPN--RNYTHQVVTRWYRAPELLFGARSY--------
 . ||.    . ..| .  |.|.|.. .|   .||||.|  |.|||  | ||..|||||| . | .  | ||  |.| |||.|||| |.  |        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------GVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEYMA-LN
                              |  ||.||.||| .||. . |||.|.  ..|| ||. | | |.|. ||. ...  .  .||. .|   | 
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

YYFS------AAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYF
  |.        |.. |||. .| . || || | .. || ..|
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase cdk-7.AA RCK 5-289 39 6.2e-90 285.53 In-house 1-298 (298) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-298/298
Sequence Identity: 39% (121 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIK--LGSREEAKDGINRTAIREIKLLKEIH-HDNIIGLRDVIGHRT--SIQLVFDFMDTDLEHVIKD--
| .|| ||.| .  | .||..|.|| ||||| |  . | ||..        |||| |. .. |.||| |..|| ...  .  .|| .||..|   .||  
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECM------NLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFK

-KEIILMPAH--IKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNK---------MGRVKLTDFGLARFFGSPNRNYTHQVVTRWYRAPELLFGARSYGV
 ..  |      ||||  | |.||...| | . |||||| |.. ..          ...|..||||.| . | . .||  | ||||||||.|  .  |  
ERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRS-KPPYTDYVSTRWYRAPECLLRCTYYNS

GIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIK-PQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSL
 .|||.||||..||   .| ||| | |||. || ...| |....||   .  | . .. || . | |. ... ..||...||  | . || || |  |.|
PMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQAL

QMEYF
|. ||
QHPYF
Kinase cdk-7.AA MAPK 5-289 33 3.9e-88 299.11 In-house 1-328 (328) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-328/328
Sequence Identity: 33% (111 aa)

YDTIKHLGEGQFANVYLAQDLE------SGECVAIKKIK--LGSREEAKDGINRTAIREIKLLKEI-HHDNIIGLRDVIGH------RT-----SIQLVF
|. .| .|.| .  |  | | .      .|. ||||||     .   .|      ..||||||... ||.|||.|.|..        ..      | .|.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK-----RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVM

DFMDTDLEHVIKDKEIILMPAHIKNITMQMLLG--LEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGS-PNRNY-------------THQVVT
..|.||| ..||    .|   ||. .. |.| |  | ..|   ..|||||| |.|.|. . .|. |||||| . .  . ..             |  |.|
ELMETDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVAT

RWYRAPELLFG--ARSYGVGIDIWSVGCIIAELLL-RNPIFPGESDIDQLVKIFNILGCPTPETWPNMT-EMNSYVIIK-----PQTEYMALNYYFSA--
|||||||....  .. |  ..|.|||||| ||.|  | |.|||.. |||. .|...|| |..| . ...   . .  |.     |..    .   |.   
RWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNAN

--APQDLLDLMAGMWTFDPIKRLTCTQSLQMEYF
  |  . .||.  | .||| ||.|  . || .||
FNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase cdk-7.AA CCRK 5-289 44 6.9e-85 288.33 In-house 1-285 (285) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-285/285
Sequence Identity: 44% (130 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDN-IIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEIILM
|  .  .|||    |. |. .| || ||.||. |       |||  .|.|||| |.||  .  .. |.||  | |   |||.||  ||  |... .  | 
YCILDRIGEGAHGIVFKAKHVETGEIVALKKVAL---RRLDDGIPNQALREIKALQEIEDNQYVVQLKDVFPHGTGFVLVFEFMLSDLAEVVRHAQRPLA

PAHIKNITMQMLL-GLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPN-RNYTHQVVTRWYRAPELLFGARSYGVGIDIWSVGCIIAELLL
.| .|   ||||| |. . |   |.|||||| |||. . |..|. |||||| |   . | ||||| ||||||||||.||| |  |.|.|.||||. ||| 
EAQVKSY-MQMLLKGVAHCHENNIMHRDLKPANLLISESGHLKIADFGLARVFSNDEGRQYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLN

RNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIK-PQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYF
  |||||| ||.||  .  ||| ||| .||.|...  |  |  .    | |      |  . |||.     . | .|..  | |  .||
NSPIFPGENDIEQLCCVLRILGTPTPKVWPEMKDLPDYNKISFKEQPPMPLEQVVPDASPQALDLLKQFLVYPPRQRIAASQALLHQYF
Kinase cdk-7.AA TyrKc 5-289 21 7.6e-14 1.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEI--HHDNIIGLRDVIGHR-------TSIQLVFDFMDT-DLEHV
   .| ||||.|  ||...     . ||.|..| ..         .  .||.......  ||.||. |  |. .          . .|. .|.  || . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IKDKEIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSP------NRNYT------HQ--VVTRWYRAPELLFGA
.....  | ...  ..  |   | |.|| . . ||||   | | .. ..|| .||||.|. ..          |.          .  ||. ||| .   
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NY

RSYGVGIDIWSVGCIIAELLLRNPIFPGE--------SDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEYMALNYYFSAAPQDLLDLMAGMWTF
. .    |.|| |  . |.. .    . .        ... ..||  . . .|     | |                     |  .|... ..|   | .
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS--------------------FVCCPDEMYQIMKQCWHE

DPIKRLTCTQSLQMEYF
|| .| | ..    |.|
DPEDRPTFSEI--HECF
Kinase cdk-7.AA Pkinase_Tyr 5-153 29 9.2e-08 26.91 Pfam 1-159 (270) Show / Hide 
Range on Protein: 5-153
Range on HMM: 1-159/270
Sequence Identity: 29% (48 aa)

YDTIKHLGEGQFANVYLAQDL----ESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEI-HHDNIIGLRDVIG-HRTS--IQLVFDFMDT-DLEHVI
   .| ||||.| .||..       . .  ||.|..| |. .|.   . .  .||.|..|.. ||.||. |  |.  .. .  | .|. .|   || .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN--CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KDK---EIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLAR
...   .  | . .. .. .|   |.|.|. . . ||||   | | .. . || .||||||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR