Gene F26A1.4 (Nematode worm)

F26A1.4

Species: Nematode worm
Alias: F26A1.4, F26A1.4na2786-3858, aSWK109, CE29038
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: III: 4813094-4814522, WormBase Genetic Map location: III:-2.56,

Classification

Group: CK1
Family: TTBKL

Sequence

Name Sequence Type Origin Length Description Download
F26A1.4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 235 Kinase domain by global Sugen HMM Fasta, JSON
F26A1.4.AA Protein Genbank 310 None Fasta, JSON

Protein domain

Protein domains of F26A1.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F26A1.4.AA TTBKL 86-260 33 1.3e-83 282.12 In-house 88-288 (288) Show / Hide 
Range on Protein: 86-260
Range on HMM: 88-288/288
Sequence Identity: 33% (67 aa)

DVRRALPHKR-ITDRTLYRAMAQVLKALALVHRAEFLHRDIKPPNCCIGATD-----CTRIYLIDYVLTRQYLDKCG-----------TVRNPRP---GL
|.|. .|.|. ..|.| .| . |.|.|| ..|.. |.|||.|| |||.|..|     | ..||||. ..|||..|.|           ..| ||.     
DLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKA

GLRGTMRYMSLDAHARQDLGPKNDLVSFLYTTIECGDGCLPWSYEKSEENCIKLKQAHIGEKLCIKKP-------LMTKAAEYIESLNYHSIPDYEKLLA
..|||.||.|...|.|...|...||.|..|..||. .| |||............|.....|.|. ..|        ..| .....||.|.. ||||....
PFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYE

LI
..
CF
Kinase F26A1.4.AA CK1 86-256 29 8.7e-62 211.58 In-house 117-339 (339) Show / Hide 
Range on Protein: 86-256
Range on HMM: 117-339/339
Sequence Identity: 29% (65 aa)

DVRR--ALPHKRITDRTLYRAMAQVLKALALVHRAEFLHRDIKPPNCCIGATDC--------------TRIYLIDYVLTR-QYLDKCGTV----------
|.|.  ... ......| .. . | |.||  .|.. |.|||||| |.|.|. ..               ..|.||. . | .|.|| |..          
DLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTW

--RNPRP---GLGLRG-TMRYMSLDAHARQDLGPKNDLVSFLYTTIECGDGC--LPWSYEKSEEN-----CIKLKQAHIGEKLCIKKP------------
  | ||.     |.|| | ||.|...| ....|.. ||.| .|. ||. .|.  |||.  |.|..      .| |...| ||..  ..            
QHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFFLCCPKKDHDCP

-LMTKAAEYIESLNYHSIPDYEKL
  . | ..||.||.|...||||..
QEF-KIMKYIRSLKYYDRPDYEMI
Kinase F26A1.4.AA TTBK 86-256 36 3.9e-33 114.45 In-house 84-257 (257) Show / Hide 
Range on Protein: 86-256
Range on HMM: 84-257/257
Sequence Identity: 36% (63 aa)

DVRRALPHKRITDRTLYRAMAQVLKALALVHRAEFLHRDIKPPNCCIG--ATDCTRIYLIDYVLTRQYLDKCGTVRNPRPGLGLRGTMRYMSLDAHARQD
| ||. |    .  |  |   |.|...  .|   |||||||| |  .|  .  | ..|..|. | |||.  || || ||.  | ||| || |  ||  ..
DLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNRE

LGPKNDLVSFLYTTIECGDGCLPWSYEKSEENCIKLKQAHIGEKLCIKKPL-MTKAAEYIESLNYHSIPDYEKL
.| . || |  |  .|   | |||   |  .   ..|.      |    |  .    . |.||||   |||  .
MGRHDDLWSLFYMLVEFVQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase F26A1.4.AA Worm6 85-256 30 9.2e-32 111.3 In-house 90-279 (279) Show / Hide 
Range on Protein: 85-256
Range on HMM: 90-279/279
Sequence Identity: 30% (57 aa)

RDVRRALPHKRITDRTLYRAMAQVLKALALVHRAEFLHRDIKPPNCCIGA------TDCTRIYLIDYVLTR--QYLDKCGTVRNPR-PGLGLRGTMRYMS
.| |...| .... .| ..   | |.|.  .|.. |.|||.||.| |||        .  .||..|. ..|  .|..| ...|.|| .  | ||| ||..
WDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAP

LDAHARQDLGPKNDLVSFLYTTIECGDGCLPWSY-------EKSEENCIKLKQAHIGEKLCIKKPL--MTKAAEYIESLNYHSIPDYEKL
| .| .|....| |. | .|  .|   |||||         ||  . |.. ..| . . .  . |   ...  .|| ...|.. |||...
LACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase F26A1.4.AA CK1-Unique 107-196 28 7.2e-14 44.48 In-house 125-219 (337) Show / Hide 
Range on Protein: 107-196
Range on HMM: 125-219/337
Sequence Identity: 28% (27 aa)

QVLKALALVHRAEFLHRDIKPPNCCIGATD---CTRIYLIDYVLTRQ--YLDKCGTVRNPRPGLGLRGTMRYMSLDAHARQDLGPKNDLVSFLYT
|.| ..   | ..|.||..|| | | .|        .| .||   |    ..... .|.|||    ||. .| .   |  ...| . |. |..|.
QCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCPCSCHQCREHGRRDDMESWFYM
Kinase F26A1.4.AA CK1-A 107-256 30 4e-13 42.58 In-house 103-261 (261) Show / Hide 
Range on Protein: 107-256
Range on HMM: 103-261/261
Sequence Identity: 30% (49 aa)

QVLKALALVHRAEFLHRDIKPPNCCIGAT-DCTRIYLIDYVLTRQYLDKCGTVRNP-RPGLGLRGTMRYMSLDAHARQDLGPKNDLVSFLYTTIECGDGC
|..  .  ||   |.|||||| |  .|    | ...|||. |...| |.      | |    | || || |..||   .   . |. |. |  .    | 
QMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGK

LPWSYEKSE------ENCIKLKQAHIGEKLCIKKPL-MTKAAEYIESLNYHSIPDYEKL
|||   |        |     | .   |.||   |  ..   .|. .| ..  |||  |
LPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase F26A1.4.AA CK1-D 107-256 30 8.7e-11 34.12 In-house 103-261 (261) Show / Hide 
Range on Protein: 107-256
Range on HMM: 103-261/261
Sequence Identity: 30% (48 aa)

QVLKALALVHRAEFLHRDIKPPNCCIG-ATDCTRIYLIDYVLTRQYLDKCGTVRNP-RPGLGLRGTMRYMSLDAHARQDLGPKNDLVSFLYTTIECGDGC
|... .  .|  .|.|||||| |  .|       .|.||. |...| |       | |    | || || |.  |   .   . || |  |  .    | 
QMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGS

LPWS-------YEKSEENCIKLKQAHIGEKLCIKKPL-MTKAAEYIESLNYHSIPDYEKL
|||         .| |  | |  . .| ..||   |.  ..  .|  .| .   |||  |
LPWQGLKAATKRQKYERICEKKMSTKI-DTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase F26A1.4.AA CK1 107-179 36 3.4e-10 31.49 In-house 113-188 (271) Show / Hide 
Range on Protein: 107-179
Range on HMM: 113-188/271
Sequence Identity: 36% (28 aa)

QVLKALALVHRAEFLHRDIKPPNCCIGA--TDCTRIYLIDYVLTRQYLD-KCGTVRNPRPGLGLRGTMRYMSLDAH
| .. .  ||   |.|||||| | ..|    .|...|.||. |  .|.| | ..    | . .| || ||.|. .|
QMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTH
Kinase F26A1.4.AA Dual 107-196 32 4.1e-10 30.08 In-house 121-212 (282) Show / Hide 
Range on Protein: 107-196
Range on HMM: 121-212/282
Sequence Identity: 32% (30 aa)

QVLKALALVHRAEFLHRDIKPPNCCIG-ATDCTRIYLIDYVLTRQYLD-KCGTVRNPRPGLGLRGTMRYMSLDAHARQDLGPKNDLVSFLYT
| |.|.   | . .|||.||| |  .|   | | .|. |. . | |.| . . .| .| ..   |. || .      .| | | || .  |.
QMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQGRKDDLECWIYM
Kinase F26A1.4.AA CK1-Unclassified 107-154 34 5.7e-10 25.63 In-house 112-163 (244) Show / Hide 
Range on Protein: 107-154
Range on HMM: 112-163/244
Sequence Identity: 34% (18 aa)

QVLKALALVHRAEFLHRDIKPPNCCIG--ATDCTRIYLIDYVLTRQYL--DK
| .. . ..|.  |.|||||| | ..|      ...|.||. |   |.  ||
QMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDK
Kinase F26A1.4.AA TTBKL 69-85 41 5e-06 16.41 In-house 1-17 (288) Show / Hide 
Range on Protein: 69-85
Range on HMM: 1-17/288
Sequence Identity: 41% (7 aa)

FEVEGIIGGGGFAQIYR
......||.|||.|.|.
WMIVKMIGEGGFGQVYH
S_TKc F26A1.4.AA S_TKc 1-274 13 6e-06 -90.17 SMART 16-231 (231) Show / Hide 
Range on Protein: 1-274
Range on HMM: 16-231/231
Sequence Identity: 13% (41 aa)

MSCERKD---------VEKKEKEEKKADESKKKDEKKEEKSKGKEDEKKENQKIAGAVHNQMKNINYMAEGSVISGRFEVEGIIGG--GGFAQIYRDVRR
. |  |.         .                           |. ..| |      |    .. .. .    .  . |   ..|  |   .. .. .|
YKCRHKKTGRIVAIKIIK--------------------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

ALPHKRITDRTLYRAMAQVLKALALVHRAEFLHRDIKPPNCCIGATDCTRIYLIDYVLTRQYLDKCGTVRNPRPGLGLRGTMRYMSLDAHARQDLGP-KN
  ......  .  . |.|...||.  |.  ..|||.|| |  .      .| ..|  | ||.               . ||  ||.         |. | 
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKC

DLVSFLYTTIECGDGCLPWSYEKSEENCIKLKQAHIGEKLCIKKPLMTKAAEYIESLNYHSIPDYEKLLALIEEC---NPA-----DLKE-------SEP
|  |.  . .|.  |. |..    ..  .|.                                  . .. .|. |   .|.     .. .        . 
DWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPW

Y
 
F
Kinase F26A1.4.AA Dual 241-260 30 0.001794 7.39 In-house 263-282 (282) Show / Hide 
Range on Protein: 241-260
Range on HMM: 263-282/282
Sequence Identity: 30% (6 aa)

YIESLNYHSIPDYEKLLALI
|. .. | | |||. ..  .
YVNGYQYDSTPDYDYFRNCL
Kinase F26A1.4.AA Pkinase 93-130 30 0.002601 12.79 Pfam 100-139 (293) Show / Hide 
Range on Protein: 93-130
Range on HMM: 100-139/293
Sequence Identity: 30% (12 aa)

HKRI--TDRTLYRAMAQVLKALALVHRAEFLHRDIKPPNC
|...  ..... . | |.|..|.  |.  ..|||.|| |.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENI
Kinase F26A1.4.AA CK1 69-85 50 0.003217 7.18 In-house 1-18 (339) Show / Hide 
Range on Protein: 69-85
Range on HMM: 1-18/339
Sequence Identity: 50% (9 aa)

FEVEGIIGGGGFA-QIYR
..|.  ||.|||  |||.
WKVVKKIGEGGFGYQIYK
Kinase F26A1.4.AA CK1 240-254 33 0.350639 0.06 In-house 257-271 (271) Show / Hide 
Range on Protein: 240-254
Range on HMM: 257-271/271
Sequence Identity: 33% (5 aa)

EYIESLNYHSIPDYE
.|. .|..   |||.
NYCRQLHFEEKPDYM
Kinase F26A1.4.AA Pkinase 69-89 23 1.124522 3.47 Pfam 1-21 (293) Show / Hide 
Range on Protein: 69-89
Range on HMM: 1-21/293
Sequence Identity: 23% (5 aa)

FEVEGIIGGGGFAQIYRDVRR
......|| |.|.. |. ...
YHIGRKIGSGSFGCVYKCHHK