Gene jnk-1 (Nematode worm)

jnk-1

Species: Nematode worm
Alias: jnk-1, CE27574, B0478.1, aSWK193, B0478.1a
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 6957629-6963715, WormBase Genetic Map location: n/a,

Classification

Group: CMGC
Family: MAPK
Subfamily: JNK

Sequence

Name Sequence Type Origin Length Description Download
jnk-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 296 Kinase domain by global Sugen HMM Fasta, JSON
jnk-1.AA Protein Genbank 463 None Fasta, JSON

Protein domain

Protein domains of jnk-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase jnk-1.AA JNK 119-414 66 2.1e-238 798.26 In-house 1-309 (309) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-309/309
Sequence Identity: 66% (207 aa)

YQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRP--FQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ---
||||..||.|||||||.|||.|.|..|||||..||  |||..|.||||||...|...||||||...||||||..|.||.|.|||||.||.||||||.   
YQNLKFIGQGAQGIVCMAFDQVTNQRVAIKKMMRPDNFQNWMHWKRAYREFICMKCINHKNIIKMYNCFTPQETLEEFQDVYIVMEYMDWNLCQVIHSTF

MDLDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVILGMG--YKENVDVWSIGCIFGEL
|.|||||.|||.|||.|||.||||.||||||||||||||..||||||.|||.|||....||||||||||||||||||.||.  ||||||.||.|||..|.
MELDHERMSYLFYQMCCGIKHLHSMGIIHRDLKPSNIVVNQDCTLKICDFGHARTEDPTFMMTPYVVTRYYRAPEVICGMMDNYKENVDIWSVGCIMAEM

IRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTVRNYVENR---PRYQATPFEVLFSDNMFP--MTADSS-RLTGAQARDLLSRMLVIDPERRISV
||..||||| ||||||..|||.|||||..|....||.||||||||   |.||...|. .|.|..||  |..... .|| ..|||||.|||||.|..||||
IRHHVLFPGKDHIDQWNKIIEFLGTPDPHFMMQMQPHVRNYVENRNMDPYYQPYNFHEHFPDTLFPDVMQSEPKDHLTCHMARDLLFRMLVINPDDRISV

DDALRHPYV
||||.|||.
DDALQHPYI
Kinase jnk-1.AA MAPK 119-414 45 9.90000000001e-186 623.31 In-house 1-328 (328) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-328/328
Sequence Identity: 45% (153 aa)

YQNLRLIGSGAQGIVCSAFDTV------RNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLV-NHKNIIGILNCFTP-----QKKLDEFNDLYIVMELMDA
||.|. ||.||.|.||||.|.        ...|||||.||||||.||.||.|||.||.    .|.|||..|..|||     |. |.||||.|||||||..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NLCQVIQ-MD-LDHERLSYLLYQMLCGIR--HLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEA---------------FMMTPYVVTRYYRAP
.|.|.|. .. |.... .|..||.|.|..  ..|||..||||||||||.| ..|.|||.||||||..                  ..||.||.||.||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EVILG---MGYKENVDVWSIGCIFGELIR-GRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQ-P-TVRNYVENR---PRYQATPFEVLFSDNMFPMTAD
|..|.   |.|...||.||.||||.|... ...|||| |.||||..|.|.||||.. |..... .  .|||....   |.|.. |.| .|....|     
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF-----

SSRLTGAQARDLLSRMLVIDPERRISVDDALRHPYV
   ..  ||.|||..|||.||..||.|..||.|||.
---NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase jnk-1.AA p38 119-414 47 6.6e-134 451.17 In-house 1-289 (289) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-289/289
Sequence Identity: 47% (145 aa)

YQNLRLIGSGAQGIVCSAFDTVRNEQ---VAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTP-QKKLDEFNDLYIVMELMDANLCQVIQM
||||. .|||| | ||.|.|. ....   ||||||.|||| . ||||.||||.|  . .| |.|..|..|||  . ...|.| |.|...|.| | ... .
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

D-LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVILG-MGYKENVDVWSIGCIFGELI
  |  ..  .|.||.| | .  ||||||||||||||| |  || |.||||||||    .  || ||.|| |||||..|  | | . ||.||.|||  |||
QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR--HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELI

RGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTV-RNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRH
 ||.|||| ||||| .||.. .||||. |....|    |||....| ..   |. .|      | |.       || ||| .||..||..||.. .|..|
TGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVF------MGAN------PQAIDLLEKMLELDPDKRITAEEAMQH

PYV
|| 
PYF
Kinase jnk-1.AA CMGC 119-414 24 3.4e-132 437.08 In-house 1-513 (513) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-513/513
Sequence Identity: 24% (128 aa)

YQNLRLIGSGAQGIVCSAFDTVRN--------------EQVAIKKLSRPFQNVTHAK----------RAYRELKLMSLVN-----------------HKN
|.... ||.|. |.|....|. .|              |.|||||...|| . ..||          ||.||.|..  .|                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIGILNCFTPQ---KKLDE--------FNDLYIVMELMDANLCQVIQM-----------DLDHER------------LSYLL------YQMLCGIR--HL
|......|..    ....|        ||.||.|.|.|| .|.|.|..            |..                |..      ||.|.|.   ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAG--IIHRDLKPSNIVVRSDCTL--------------------KILDFGLARTAIEA----------------------FMMTPYVVTRYYRAPEVIL
||..  ||||||||.|| . ..|.|                    || ||||||   .                        ..|.|||||.|||||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

G----------MGYKENVDVWSIGCIFGELIRG--------RVLFP-----------GGDHIDQWTRIIEQLGTP----------------DRSFLERLQ
|          |.| . .|.||.||||.|...|        . |||           | .||||. .|.. ||||                .. . ....
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

---------------------PTVRNYVEN---RPRYQATPFEVLFSDNMFPMTADSSR-------------------------LTGAQARDLLSRMLVI
                     . .|||...    |...  |.. || .. .. .    .                         .   ||.|||..||..
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-N-NKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

DPERRISVDDALRHPYV
||..||....||.||| 
DPDKRITAEQALQHPYF
Kinase jnk-1.AA ERK 119-414 40 1.2e-112 380.56 In-house 1-307 (307) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-307/307
Sequence Identity: 40% (129 aa)

YQNLRLIGSGAQGIVCSAFDTV-----RNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVN-HKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVI
|| . .|| || |.||||.|.       .. ||||| ...| .   .||..||.||. . . |.|||.... . |  .  ..||.|.| |||.  | |.|
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE-QYNDIYCVEELMETDLHQII

QMD--LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLAR----TAIEAF-----MMTPYVVTRYYRAPEVILGM-GYKENVD
. .  |  .   |..||.|||. ..|||..|||||||||| | |.|.||| ||||||    .. |       .|| ||.||.|||||..|    | . .|
NSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMD

VWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTP-DRSFLERL-QPTVRNYVENRPR--YQATPFEVLFSD-NMFPMTADSSRLTGAQARDLLSRML
.||.|||| |..... ||||.|...| .||.. .||| .   |..   . ...|. | |   ... |.| .|.. |              || |||..||
IWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNAN-----------CNPQAIDLLEKML

VIDPERRISVDDALRHPYV
|.||. ||.|...|.||| 
VFDPDKRITVEECLEHPYF
Kinase jnk-1.AA S_TKc 119-414 26 2.2e-89 304.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-231/231
Sequence Identity: 26% (83 aa)

YQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDA---NLCQVIQMD
|. ||.||.|| | |. . ..  ...||||...         ....||.....  .|.||. .. .|         ..||.|||..|    .| ..|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKR

--------LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVILGMGYKE-NVDVWSIGC
        ..  .  ...||..|.. ..|| |||||||||.|| . .  ..|| ||||||        | ...|..|.||||.   ||    .|.||.||
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

IFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVD
|. |.. |. .||      |  ......|                                                  .|.|.....|. |||.|... 
ILYEMLCGYPPFP------QMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-

DALR-------HPYV
.||.       ||..
EALQDEWDIKCHPWF
Kinase jnk-1.AA ERK5 119-414 41 6.9e-88 298.28 In-house 1-295 (295) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-295/295
Sequence Identity: 41% (128 aa)

YQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQMD--L
|. .  || || |.||||      .||||||.   |  || ||| .||||..    | ||| | .   |.. . |. | |.|..||.. | |.|  .  .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPF

DHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLAR---T---AIEAFMMTPYVVTRYYRAPEVILGM-GYKENVDVWSIGCIFG
  | . | |||.| |.. .||| .|||||||||..|   | ||| |||.||   |   . . . || || ||.|||||... .  |   .||||.|||||
TLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIFG

ELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQP-TVRNYVEN-RPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDD
|.|  | .|||   |.|   |.. ||.|    ..      |.||.    |  |  ..| ..        ||       || |||.|||. .|  ||.|  
EMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVY------PKAD------RQALDLLARMLRFEPSERITVNK

ALRHPYV
||.||..
ALQHPFL
Kinase jnk-1.AA nmo 120-414 40 1.3e-84 260.03 In-house 2-292 (292) Show / Hide 
Range on Protein: 120-414
Range on HMM: 2-292/292
Sequence Identity: 40% (121 aa)

QNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVI--QMDLD
|  | || || |.| |  |      ||.||.   |||.  .|| .||||...  .| |..  |..  | .| | |...|.| ||| . | ..|     | 
QPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHK-DFFQEIYVVTELMQSDLHKIIVSPQHLS

HERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLART--AIEAFMMTPYVVTRYYRAPEVILGM-GYKENVDVWSIGCIFGELIRG
 . .   |||.| |.. ||||.|.|||.|| |..| |.| ||| ||||||.    ..  ||  ||| ||||||...|   | . ||.||.||||.||.  
SDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGR

RVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPYV
|.||     |.|   |.. ||||    .       .. .  .|  .   ..||.       |  |       | .||.|||. ||..|||. ||| |||.
RILFQAQSPIQQLQMITDLLGTPSMEDMKYACEGAKAHMLRMPHKPPC-LQVLY-------TLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase jnk-1.AA ERK1 119-414 40 1.1e-78 267.69 In-house 1-289 (289) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-289/289
Sequence Identity: 40% (124 aa)

YQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQM-DLD
| ||. || || |.|||| |||....|||||.| ||   |. .|  ||.|..   .| |||.| .     . .... |.||| .||.  | ....   | 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKIS-PFEHQTYCQRTLREIKILTRFKHENIINIQDIIR-ADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

HERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAF----MMTPYVVTRYYRAPEVIL-GMGYKENVDVWSIGCIFGELI
 . . | |||.| |.. .||| ..||||||||...   | ||| |||||| |         .| || ||.|||||..|   ||   .|.||.|||  |..
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML

RGRVLFPGGDHIDQWTRIIEQLGTPDRSFLER-LQPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRH
  | .|||   .||   |.  || | .  |.  .    |||..  |  .  |.. || .      ||      ..| ||| .||   |..|| |..|| |
SNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPK------AD------SKALDLLDKMLTFNPHKRITVEEALAH

PYV
||.
PYL
Kinase jnk-1.AA ERK7 119-414 37 1.7e-78 267.12 In-house 1-292 (292) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-292/292
Sequence Identity: 37% (115 aa)

YQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVN-HKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ--MD
|. .. .| || |||  |.|    . ||.||    |.| | | | .||  ..   . | ||| ..| .    . |   |.|.| | |.. |  ||.    
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVI----RADNDRDIYLVFEFMETDLHAVIRKGNI

LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAF-------MMTPYVVTRYYRAPEVILG-MGYKENVDVWSIGCI
|      | .||.|  |...||. .|||||||||| . |.|..|. ||||||.  .         |.| || || |||||. ||   |   || ||||||
LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCI

FGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDD
 ||..||. .|||   ..|  .|.| .. | .  .| ... ..  . ..     .. . |  |.|.|.. |       .| ||| |.||  |..|.....
LGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN--QQKRKTL--DQMMPQCCD-------DAIDLLKRLLVFNPKKRLTAEQ

ALRHPYV
||.||||
ALQHPYV
Kinase jnk-1.AA Pkinase 119-414 26 3.1e-73 254.42 Pfam 1-293 (293) Show / Hide 
Range on Protein: 119-414
Range on HMM: 1-293/293
Sequence Identity: 26% (86 aa)

YQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYR--ELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDA-----NLCQV
|. .| ||||. | |. . .   ...||.|..... ..    ... |  |...|  .||.||. .. .|.        ...|.|||...       |. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY

IQ-------MDLDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTL----KILDFGLART--AIEAFMMTPYVVTRYYRAPEVIL-GMGYKE
|.       . .. . .   .||.|.|. ..|| |||||||||.|| . .....    || |||||.         || ...|..|.|||||. | .|  
ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

NVDVWSIGCIFGELIRGRVLFPGG----DHIDQWTRIIEQLGTPDRSFLERLQPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSR
 ||.||.|||. |.. || .|||     . .||  .| . .|.| ..  . . .  . .  .. .               . .     ..   ..|....
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------------F-HWTF-HNWSEECKDFIKW

MLVIDPERRISVDDALRHPYV
.|  ||..|.. ...| ||..
CLCKDPKKRPTAEQILQHPWF
Kinase jnk-1.AA MAPK-Unclassified 119-267 44 1.6e-56 194.11 In-house 1-157 (575) Show / Hide 
Range on Protein: 119-267
Range on HMM: 1-157/575
Sequence Identity: 44% (70 aa)

YQNLRLIGSGAQGIVCSAFDTVR-NEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLD-EFNDLYIVMELMDA---NLCQVIQ
|    .||||| |.|| | |.   | ||||||. . |.|.| .||. ||. .    || ||| | . |..   .  || |.||||..|     .| |.|.
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

MDL---DHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLAR
 ..    |.   |..|| | |.  ||||.||||||||||. .  ||...| |||..|
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase jnk-1.AA MAPK-Unclassified 275-414 33 4.2e-37 129.58 In-house 405-575 (575) Show / Hide 
Range on Protein: 275-414
Range on HMM: 405-575/575
Sequence Identity: 33% (58 aa)

MTPYVVTRYYRAPEVILGMG-YKENVDVWSIGCIFGELIRG-----------RVLFPGGD--------------------HIDQWTRIIEQLGTPDRSFL
|| |||||.||||| .| |. |   || |||||||.|..             | |||| |                    |.||   |.. ||.|.   .
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC

ERLQ-PTVRNYVENRPRYQATPFEVLFSDNMFPMTA--DSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPYV
 . . . .| |..   .       | |.| ||. .   |       ...|... ||...| .||. |.|| |||.
NFITCDSARKYIQSFKCKT----PVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase jnk-1.AA TyrKc 119-391 22 6e-14 2.87 SMART 1-280 (280) Show / Hide 
Range on Protein: 119-391
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

YQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLV--NHKNIIGILNCFTPQKKLDEF---NDLYIVMELMDA-NLCQVI
 . .. .|.|| |.|. .  .   .|||.|.|          .  .||...|. .  .|.||. .. . | |.    |     |.||||.|.  .| . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYL

-QMD--LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEA---------FMM-----TPYVVTRYYRAPEVILGMGY
      | .. | .  .|  || ..||| ..|||||   |. | .. | || ||||.|   .           ..     . ...     |||.|    .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

KENVDVWSIGCIFGELI-RGRVLFPG---GDHIDQWTRIIEQLGTPDRSFLERL----QPTVRNYVENRPRYQATPFEVLFSDNMFPMTAD------SSR
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TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------F-VCCPDEMYQIMKQCWHEDPEDR

LTGAQARDLL
 | .. ....
PTFSEIHECF
Kinase jnk-1.AA Pkinase_Tyr 119-268 28 1.8e-08 29.29 Pfam 1-160 (270) Show / Hide 
Range on Protein: 119-268
Range on HMM: 1-160/270
Sequence Identity: 28% (47 aa)

YQNLRLIGSGAQGIVCSAFDT----VRNEQVAIKKLSRPFQNVTHA----KRAYRELKLMSLV-NHKNIIGILNCFTPQKKLDEFNDLYIVMELMDA-NL
 . .. .|.|| | |. .  .      . .||.|.| ..  . .|     .   ||.|.|.   .|.||.  . . |.|..      .|||||.|   .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDL

CQVIQMD------LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLART
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LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD