Gene T05A7.6 (Nematode worm)

T05A7.6

Species: Nematode worm
Alias: T05A7.6Nna18220-17630, aSWK077, CE04892, T05A7.6
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: II:-2.91, WormBase Physical Map location: II: 4671759-4668639, Secondary Group: CK1, Secondary Family: Dual

Classification

Group: CK1
Family: Dual

Sequence

Name Sequence Type Origin Length Description Download
T05A7.6.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 233 Kinase domain by global Sugen HMM Fasta, JSON
T05A7.6.AA Protein Genbank 758 None Fasta, JSON
T05A7.6.kin_dom2 Protein Kinase Domain Sugen global kinase HMM prediction 276 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of T05A7.6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase T05A7.6.AA Dual 101-367 51 8.60000000001e-179 600.26 In-house 13-282 (282) Show / Hide 
Range on Protein: 101-367
Range on HMM: 13-282/282
Sequence Identity: 51% (140 aa)

KVTSQLRKSSKLLDYDVYLVKDTESGDDYRMKVARKDPQILKTEAALLRRLEKIPGDKCFISMIEYGSIVKDKVEFLIVSPYGATLNEIMKKATMGQLSM
.. ......|.... ... ...||| . ..|....|. .... ..|..|..||||||||||....||....||......||||..|.||..|..||||||
RDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQEIRRKYIMGQLSM

DCSFVVGLQMLRAIQNLHSIGYIHRNISPASFHCGLGMDEPTLFLQDFRQARKFEE--NKKHVTARTNVKMYGCGRFANRACQGSKDQGRKDDLESWVYT
.|||.|..|||||||.||||||.||||.||.|||||||||.|...||||..||...  ||||.|||..||||||||.|.|||...||||||||||.|.|.
HCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQGRKDDLECWIYM

LFYLMDNGS-LSWKRENNSLVVIQQKDAFMAGNGKDQFTHAPRDLVPLLSVINGYEFSSAPDYEVFRNCL
.|.|||... .||..|......|.|||.||....|.|..|.||.|.||.|..|||...|.|||..|||||
VFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL
Kinase T05A7.6.AA CK1 115-363 20 7.4e-69 235.07 In-house 14-339 (339) Show / Hide 
Range on Protein: 115-363
Range on HMM: 14-339/339
Sequence Identity: 20% (67 aa)

YDVYLV-----KDTESG-----DDYRMKVARKD----PQILKTEAALLRRLEKI----------------PGDKCFISMIEYGSIVKDKVEFLIVSPYGA
|..|.|     ||....     ..| ||| .|.    .  |. |. ... |...                .  .... |..|.  ..|.  ... . .| 
YQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEEDDYYNYMVMTLLGP

TLNEIMK--KATMGQLSMDCSFVVGLQMLRAIQNLHSIGYIHRNISPASFHCGL-------------GMDEPTLFLQDFRQAR-KFE-------------
.| ...|  .   . .|| ... ...||| |.. .|..|.|||.| |. |..|.             .... .... ||  || |.              
NLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRD

ENKKHVTART---NVKMYG-CGRFANRACQGSKDQGRKDDLESWVYTLFYLMDNGS-LSWKRENNSLV-----VIQQKDAFMAG--NGKDQF-------T
....| ..|.   .... | . |.. ..|.  |.|||.|||.|| |.|..... .. | |.  .         |...| .|..   .   .|       .
KTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFFLCCPKKDH

HAPRDLVPLLSVINGYEFSSAPDYEVF
. |... ... .|........|||| .
DCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase T05A7.6.AA Worm6 116-363 24 1.2e-27 96.32 In-house 14-279 (279) Show / Hide 
Range on Protein: 116-363
Range on HMM: 14-279/279
Sequence Identity: 24% (65 aa)

DVYLVKDTESGD--DYRMKVAR----KDPQILKTEAALLRRLEKIPGDKCFISMIEYGSIVKDKVEFLIVSPYGATLNEIMKKATMGQLSMDCSFVVGLQ
.||.|.|.. .    . ||. .       | || |.. | ......  . | .....| . ..   ...   .|  | ...| .  . .|| ..  ...|
AVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHK-CRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQ

MLRAIQNLHSIGYIHRNISPASFHCGL-----GMDEPTLFLQDFRQAR--KFEENKK-HVTAR-TNVKMYGCGRFANRACQGSKDQGRKDDLESWVYTLF
.|.||. ||..|.|||.. |. | .|        .. |... ||  .|  |. ....   | | |...  |  |.| .||   ..|.||||.||| | . 
CLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMV

YLMDNGSLSWKRENNSLVVIQQKDAFMAGNG---KDQFTH-APR-DLVPLLSVINGYEFSSAPDYEVF
 .   | | |.  . .  | ..| . .  .    . .|    |. ...  . .| .| . ..|||.  
EMI-VGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase T05A7.6.AA CK1-Unique 207-311 27 8.3e-22 72.4 In-house 123-233 (337) Show / Hide 
Range on Protein: 207-311
Range on HMM: 123-233/337
Sequence Identity: 27% (31 aa)

GLQMLRAIQNLHSIGYIHRNISPASFHCGLGM--DEPTLFLQDFRQARK---FEENKKHVTARTNVKMYGCGRFANRACQGSKDQGRKDDLESWVYTLFY
|.| | .|   |  |..||.. |.... .     .. ...  |.   |.    . |      |  ... || ... ..| . ...||.||.|||.|.|  
GYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCPCSCHQCREHGRRDDMESWFYMLYH

LMDNG-SLSWK
| .|   ||||
LVHNTRGLSWK
Kinase T05A7.6.AA CK1-D 197-311 31 1.1e-17 58.9 In-house 91-206 (261) Show / Hide 
Range on Protein: 197-311
Range on HMM: 91-206/261
Sequence Identity: 31% (37 aa)

QLSMDCSFVVGLQMLRAIQNLHSIGYIHRNISPASFHCGLGMDEPTLFLQDFRQARKFEENK--KHVTARTNVKMYGCGRFANRACQGSKDQGRKDDLES
. |.    ....||.. |. .|.  .||| | |  |  |||    . .. ||  |... . .  .|.  | |  . |  |.|        .| |.|||||
KFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLES

WVYTLFYLMDNGSLSWK
  | | |    ||| |.
LGYVLMYFN-RGSLPWQ
Kinase T05A7.6.AA CK1-A 209-311 33 1.3e-14 47.96 In-house 103-206 (261) Show / Hide 
Range on Protein: 209-311
Range on HMM: 103-206/261
Sequence Identity: 33% (35 aa)

QMLRAIQNLHSIGYIHRNISPASFHCGLGMDEPTLFLQDFRQARKF--EENKKHVTARTNVKMYGCGRFANRACQGSKDQGRKDDLESWVYTLFYLMDNG
||.  |  .|  ..||| | |  |  |.|     ||| ||  |.|.  .. ..|.  |.  .. |  |.|    .   .| |.||.||  | . |    |
QMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMY-FNRG

SLSWK
.| |.
KLPWQ
Kinase T05A7.6.AA TTBK 183-299 29 4.9e-12 38.87 In-house 79-197 (257) Show / Hide 
Range on Protein: 183-299
Range on HMM: 79-197/257
Sequence Identity: 29% (35 aa)

GATLNEIMKKATMGQLSMDCSFVVGLQMLRAIQNLHSIGYIHRNISPASFHCG-LGMDEPTLFLQDFRQARKFEENKKHV-TARTNVKMYGCGRFANRAC
|  | .   |.  |  |.     .|.|.| .|.  ||.|. || | |  |  | .       .. ||  ||..   .  | ..|      |  |.|    
GKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINA

QGSKDQGRKDDLESWVYTL
  ... ||.||| |  | |
HRNREMGRHDDLWSLFYML
Kinase T05A7.6.AA CK1-Unclassified 207-302 34 3.2e-11 29.37 In-house 110-209 (244) Show / Hide 
Range on Protein: 207-302
Range on HMM: 110-209/244
Sequence Identity: 34% (35 aa)

GLQMLRAIQNLHSIGYIHRNISPASFHCG-LGMDEPTLFLQDFRQARKFE---ENKKHVTARTNVKMYGCGRFAN-RACQGSKDQGRKDDLESWVYTLFY
. ||.  |..||. ..||| | |  |  | ||    .... ||  . ..    ...||.. | | .. |  |.|  .| .| . |.|.|||||  |.| |
ADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLG-IEQSRRDDLESLGYVLIY

L
.
F
Kinase T05A7.6.AA CK1 206-302 30 2.7e-10 31.83 In-house 110-209 (271) Show / Hide 
Range on Protein: 206-302
Range on HMM: 110-209/271
Sequence Identity: 30% (30 aa)

VGLQMLRAIQNLHSIGYIHRNISPASFHCGL-GMDEPTLFLQDFRQARKF--EENKKHVTARTNVKMYGCGRFANRACQGSKDQGRKDDLESWVYTLFYL
.. ||.. |. .|. ..||| | |  |  |. | .. .... ||  | ..   ....|.  |.| .. |  |.|       . |.|.||.||  | |.|.
IADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDMESLGYVLMYF
Kinase T05A7.6.AA TTBKL 284-367 24 2.2e-08 24.52 In-house 204-288 (288) Show / Hide 
Range on Protein: 284-367
Range on HMM: 204-288/288
Sequence Identity: 24% (22 aa)

KDQGRKDDLESWVYTLFYLMDNGSLSWKRENNSLVVIQQKDAFMAGNGKDQFTH------APRDLVPLLSVINGYEFSSAPDYEVFRNCL
|.|||.||| || |.. .|..   | |.....   ... | .    ...| |         |. . .    .   .. . |||| ...|.
KEQGRHDDLWSWMYMIIELHCG--LPWTNMEDKMEIEHMKKNM---KDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase T05A7.6.AA TTBKL 117-230 24 4.1e-08 23.56 In-house 15-131 (288) Show / Hide 
Range on Protein: 117-230
Range on HMM: 15-131/288
Sequence Identity: 24% (29 aa)

VYLVKDTES-GDDYRMKV-ARK-D--PQILKTEAALLRRLEKIPGDKCFISMIEYGSIVKDKVEFLIVSPYGATLNEIMKKATMGQ-LSMDCSFVVGLQM
||.|.|... .| . ||.  .. .  ....| |. .| .| . .| . |. ....| .  ..  |.. .  |  |  ..|.   .  .|   . ..| | 
VYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQP-NGSPHFPKCHCSGKR--KDYNFMVMTLCGPNLQDLRKMMPNKKRFSDGTWSRIGIQC

LRAIQNLHSIGYIHRNISPA
| |.. .|..|.||| . |.
LYALKQMHDCGFIHRDVKPC
Kinase T05A7.6.AA Dual 440-715 63 9.80000000001e-204 683.12 In-house 1-282 (282) Show / Hide 
Range on Protein: 440-715
Range on HMM: 1-282/282
Sequence Identity: 63% (179 aa)

WKVVNLLGSGGFGDVYKVHRESQ--ASNKCYALKTESEEGEKRYLRLKVEVTVMMKTAEKKKDNK---FKNFIEFVDRGKCEQLKCKFVVMGLVGPSLED
||||||||||||.|||.|||.||  ..||||.||||||||||..||||||..||||.|||.|..|   .|.||||||.|||||.|||..||...||||..
WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQE

IRRKYLLASFSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGLDEREDTVYMLDFGIAKLYVD-ENGVHKIKRKKVKFLGTLRYACRACMMQQEQ
|||||.....|.|.|||||||...|..||||.|||||.|||||...||...|.||||.||.|...|.| ||..|...|||||..|..||||||||||..|
IRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQ

GRKDDLETWIYLVFDLMDEAHGMPWRALCDPREILKSKNTFFATFDNFQFSNILKRLKDLVVYVDDMQYDTTPDYSYILNFL
|||||||.|||.||||||..|||.||..||.....|.|..|...||..|.|.|..|||.||.||...|||.||||.|..|.|
GRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL
Kinase T05A7.6.AA CK1 440-711 25 4.4e-98 332.17 In-house 1-339 (339) Show / Hide 
Range on Protein: 440-711
Range on HMM: 1-339/339
Sequence Identity: 25% (88 aa)

WKVVNLLGSGGFG-DVYKV-----HRESQA---SNKCYALKTESEEGEKRYLRLKVEVTVMMK------------TAEKKKD-NKFKNFIEFVDRGKCEQ
|||| ..|.|||| ..|||      ...     ....||.|.|... .... .|..|. ...|            ..... . .... ..  .. ...|.
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

LKCKFVVMGLVGPSLEDIRR--KYLLASFSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGL-------------DEREDTVYMLDFGIAK-LYV
 .....|| |.||.|||.|.  .     ||. |....|||.. ||...|. |..||||||.|...|.             ......|||.|||.|.  |.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

DENG------------VHKIKRK---KVKFLG-TLRYACRACMMQQEQGRKDDLETWIYLVFDLMDEAHGMPWRALCDPRE-----ILKSKNTFFATFDN
| .|            .|. .|.   |..| | |.||. ..|. ..||||.|||..|.|.......  .|.||. . |. .     . | |  |.... .
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

FQFSN---------ILKRLKDLVVYVDDMQYDTTPDYSYI
 . ..         . . . ... |.. ..|...||| .|
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase T05A7.6.AA Worm6 440-711 34 1.3e-78 267.45 In-house 1-279 (279) Show / Hide 
Range on Protein: 440-711
Range on HMM: 1-279/279
Sequence Identity: 34% (100 aa)

WKVVNLLGSGGFGDVYKVHRESQASNKCYALKTESE-EGEKRYLRLKVEVTVMMKTAEKKKDNKFKNFIEFVDRGKCEQLKCKFVVMGLVGPSLEDIRRK
|||. ..|.||||.|||| ..|  ..| .|.| |.. |..||   ||.|. |..... .|     ..| ...|||| ..   ...|| |||..|.|.|. 
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQM-LKMECMVLKAVKHHK----CRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKN

YLLASFSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGL-----DEREDTVYMLDFGIAK--LYVDENGVHKIKR-KKVKFLGTLRYACRACMMQ
     ||  |.  .|||.  |..|||. |..|||.||.|...|      |. . |.||||||...   | ..... .  | ....| ||.||| .||. .
RPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKG

QEQGRKDDLETWIYLVFDLMDEAHGMPWRALCDPREILKSKNTFFATFD----NFQFSNILK-RLKDLVVYVDDMQYDTTPDYSYI
|||.||||.|.| |.. ..     . ||| . |. .  | |     . .     . | .. |  ..|   |.| ..| ..||| .|
QEQCRKDDCESWFYMMVEMIVG--CLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase T05A7.6.AA TTBKL 440-715 29 3.6e-58 195.02 In-house 1-288 (288) Show / Hide 
Range on Protein: 440-715
Range on HMM: 1-288/288
Sequence Identity: 29% (90 aa)

WKVVNLLGSGGFGDVYKVHRESQASNKCYALKTESEEGEKRYLRLKVEVTVMMKTAEKKKDNKFKNFIEFVDRGKCEQLKCKFVVMGLVGPSLEDIRRKY
|..| ..|.|||| ||.| . .. ...|.|.| |. . |.   |.| || |.|| .....    . |..... || ..  . |.|| |.||.| |.|.. 
WMIVKMIGEGGFGQVYHV-WDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGS----PHFPKCHCSGKRKD--YNFMVMTLCGPNLQDLRKMM

LLAS-FSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGLD----EREDTVYMLDFGIAKLYVDENG-----------VHKIKRK---KVKFLGTL
     ||. |.  ..||.. ||...|. |..|||.||.|...|.     ||. .|| .|||.|. |....|            .. .|.   |. | ||.
PNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTT

RYACRACMMQQEQGRKDDLETWIYLVFDLMDEAHGMPWRALCDPREILKSKNTFFATFDNFQFSN------ILKRLKDLVVYVDDMQYDTTPDYSYILNF
||.  .  . .||||.|||  |.| .  |...    ||. . |. || . |.   .. |.  |..      . . . . . ..  ..|  .|||..|...
RYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG---LPWTNMEDKMEIEHMKK---NMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYEC

L
.
F
Kinase T05A7.6.AA CK1-Unique 440-659 25 2.2e-42 144.75 In-house 1-233 (337) Show / Hide 
Range on Protein: 440-659
Range on HMM: 1-233/337
Sequence Identity: 25% (61 aa)

WKVVNLLGSGGFGDVYKVHRESQA----SNKCYALKTESEEGEKRYLRLKVEVTVMMK----TAEKKKDNKFKNFIEFVDRGKCEQLKCKFVVMGLVGPS
|.|  ..|.||.|.|..|  .       . . |. |||     |.  ||..|  ||      ... |.  .|   . |   .   .   .. || ..|||
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDF---HQHRDW--WWIVMTMHGPS

LEDIRRKYLLASFSKH------TSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGLDE--REDTVYMLDFGIAKL--YVDENGVHKIKRKKVKFLGTLR
.| .....   .| .       .  . . |.  ...  |  |..||..||.||  .      . . ||||.|| .    |. |.. . .|....| |...
MEECCMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKD

YACRACMMQQEQGRKDDLETWIYLVFDLMDEAHGMPWR
|. ..|   .|.||.||.|.| |.  .| .   |. |.
YCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWK
Kinase T05A7.6.AA CK1-Unclassified 440-640 31 4e-30 86.12 In-house 1-200 (244) Show / Hide 
Range on Protein: 440-640
Range on HMM: 1-200/244
Sequence Identity: 31% (66 aa)

WKVVNLLGSGGFGDVYKVHRESQASNKCYALKTESEEGEKRYLRLKVEVTVMMKTAEKK-KDN--KFKNFIEFVDRGKCEQLKCKFVVMGLVGPSLEDIR
 .|.  .|.| ||..||.      .|. .|.| |..  .  .  |. |. .|.     . . .    |..      |. ||  . ..|| | ||||||. 
YRVIEKIGQGSFGEIYKC--INMQTNEEVAIKLEKKNSK--HPQLCYEAKIMQYLQNGHNC-DNFI-KGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDL-

RKYLLA-SFSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVG-LDEREDTVYMLDFGIAKLYV--DENGVHKIKRKKVKFLGTLRYACRACMMQQE
 . .    ||  |  . | | .. .  ||. ...|||||| |. .| |  . ..||. |||..| |.  |..| |   | . .. || |||        |
-FNMCNRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIE

QGRKDDLE
|.|.||||
QSRRDDLE
Kinase T05A7.6.AA TTBK 522-711 31 1.4e-29 101.77 In-house 72-257 (257) Show / Hide 
Range on Protein: 522-711
Range on HMM: 72-257/257
Sequence Identity: 31% (61 aa)

FVVMGLVGPSLEDIRRKYLLASFSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGLD-EREDTVYMLDFGIAKLYVDENGVHKIKRKKVKFLGTL
..|| | | .| | ||| .   ||  |   . .| . ...  ||.|.||||||| |.|.|.  ..   .|||||| |  |.   |     |.   | || 
YMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTV

RYACRACMMQQEQGRKDDLETWIYLVFDLMDEAHG-MPWRALCDPREILKSKNTFFATFDNFQFSNILKRLKDLVVYVDDMQYDTTPDYSYI
|||       .| ||.|||    |.   |   ..| .||| . |  .. . |. .          .. . ..  .  .  ..| ..|||  |
RYASINAHRNREMGRHDDLWSLFYM---LVEFVQGQLPWRKIKDKDQVGEMKEKYDHR---MLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase T05A7.6.AA CK1 440-640 29 4.5e-29 97.32 In-house 1-200 (271) Show / Hide 
Range on Protein: 440-640
Range on HMM: 1-200/271
Sequence Identity: 29% (62 aa)

WKVVNLLGSGGFGDVYKVHRESQASNK-CYALKTESEEGEKRYLRLKVEVTVMMKTAE-KKKDNKFKNFIEFVDRGKCEQLKCKFVVMGLVGPSLEDIRR
 .|.  .|.| |||.|.. .  .  ..  .| | |..  .  .  |. |. ...     .. ||. ...      |..|| .. ..|| | ||||||   
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSK-HP-QLHYEAKIYKILQGHNC-DNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDL--

KYLLAS--FSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGL-DEREDTVYMLDFGIAKLYVD-ENGVHKIKRKKVKFLGTLRYACRACMMQQEQ
 . . .  ||  |  ..| | .. .  .|. ...|||||| |. .|.   ....||. |||.|| |.| ... |   | . .. || |||     .  ||
-FNFCNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQ

GRKDDLE
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SRRDDME
Kinase T05A7.6.AA CK1-D 523-646 40 7.8e-23 77.27 In-house 72-195 (261) Show / Hide 
Range on Protein: 523-646
Range on HMM: 72-195/261
Sequence Identity: 40% (51 aa)

VVMGLVGPSLEDIRRKYLLASFSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGLDEREDTVYMLDFGIAKLYVDENGVHKIKRKKVKFL-GTLR
.|| |.||||||.   |    ||  |   .| | .. .  .|.  ..|||||| |. .||  | ..||..|||.|| | | .  . |  .  | | || |
MVMDLLGPSLEDL-FNYCHRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTAR

YACRACMMQQEQGRKDDLETWIYLV
||     .  || |.||||   |..
YASINTHQGIEQSRRDDLESLGYVL
Kinase T05A7.6.AA CK1-A 523-646 35 3.6e-21 71.41 In-house 72-195 (261) Show / Hide 
Range on Protein: 523-646
Range on HMM: 72-195/261
Sequence Identity: 35% (44 aa)

VVMGLVGPSLEDIRRKYLLASFSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGLDEREDTVYMLDFGIAKLYVDENGVHKIKRKKVKFL-GTLR
.|| |.||||||.   .    |.  |   .| | .. .  .|  ...|||||| |. .|..     ....|||.|| | |..  . |. .. | | || |
MVMDLLGPSLEDL-FNFCKRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTAR

YACRACMMQQEQGRKDDLETWIYLV
||     .  || |.||.|   | .
YASINAHLGIEQSRRDDMESMGYVM
Kinase T05A7.6.AA S_TKc 440-733 15 6.4e-11 -16.76 SMART 1-231 (231) Show / Hide 
Range on Protein: 440-733
Range on HMM: 1-231/231
Sequence Identity: 15% (48 aa)

WKVVNLLGSGGFGDVYKVHRESQASNKCYALKTESEEGEKRYLRLKVEVTVMMKTAEKKKDNKFKNFIEFVDRGKCEQLKCKFVVMGLVGP---SLEDIR
.......|.|.|| |||..  .  ... .|.|  .        ... |. ...|        . .| . . |       .. ..|| ...    .| |. 
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-------EHIRREIQILKK--------HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYI

RKYLLAS----FSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGLDEREDTVYMLDFGIAKLYVDENGVHKIKRKKVKFLGTLRY-ACRACMMQQ
.|.        |.  .   .. |.. ||  .||.| .|||.||.|  .       ..   |||.|...               | ||. | |   .    
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL----

EQGRKDDLETWIY----------LVFDLMDEAHGMPWRALCDPREILKSKNTFFATFDNFQFSNILKRLKDLVVYVDDMQYDTTPDYSYILNFLKT----
          . .          ... ..      |..   .. ...|                                  . .  . | . |.     
---------GYGKCKCDWWSCGCILYEMLC--GYPPFP---QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDPEK

--TANDVGA--KITKKLDWM
  || .. .     |.  |.
RPTA-EALQDEWDIKCHPWF
Kinase T05A7.6.AA TTBK 440-488 36 1e-06 19.66 In-house 1-48 (257) Show / Hide 
Range on Protein: 440-488
Range on HMM: 1-48/257
Sequence Identity: 36% (18 aa)

WKVVNLLGSGGFGDVYKVHRESQASNKCYALKTESEEGEKRYLRLKVEV
||||   | |||| .|    . .    . |.| || .  |  |.. | |
WKVVKKIGGGGFGEIYEAK-DMINHHEQVAIKVESAQQPKQVLKMEVAV
Kinase T05A7.6.AA CK1-A 440-455 50 0.000673 9.46 In-house 1-16 (261) Show / Hide 
Range on Protein: 440-455
Range on HMM: 1-16/261
Sequence Identity: 50% (8 aa)

WKVVNLLGSGGFGDVY
...|  .||| |||.|
YRLVRKIGSGSFGDIY
Kinase T05A7.6.AA Pkinase 440-461 40 0.003141 12.5 Pfam 1-22 (293) Show / Hide 
Range on Protein: 440-461
Range on HMM: 1-22/293
Sequence Identity: 40% (9 aa)

WKVVNLLGSGGFGDVYKVHRES
....  .|||.|| ||| |. .
YHIGRKIGSGSFGCVYKCHHKG
Kinase T05A7.6.AA Pkinase 555-577 47 0.028943 9.09 Pfam 116-138 (293) Show / Hide 
Range on Protein: 555-577
Range on HMM: 116-138/293
Sequence Identity: 47% (11 aa)

QTVTALRDLHSLGYLHRDIKPAN
|.. .|  .|| | .|||.||.|
QILRGLEYCHSMGIIHRDLKPEN
Kinase T05A7.6.AA CK1-D 696-711 37 0.04809 2.81 In-house 246-261 (261) Show / Hide 
Range on Protein: 696-711
Range on HMM: 246-261/261
Sequence Identity: 37% (6 aa)

YVDDMQYDTTPDYSYI
|.  ...|  |||.|.
YCRNLKFDDKPDYCYL
Kinase T05A7.6.AA CK1-A 693-711 26 0.068833 2.25 In-house 243-261 (261) Show / Hide 
Range on Protein: 693-711
Range on HMM: 243-261/261
Sequence Identity: 26% (5 aa)

LVVYVDDMQYDTTPDYSYI
.. |. ..... .||| |.
YMNYCRNLRFEEQPDYMYL
Kinase T05A7.6.AA CK1-D 440-455 43 0.075415 2.11 In-house 1-16 (261) Show / Hide 
Range on Protein: 440-455
Range on HMM: 1-16/261
Sequence Identity: 43% (7 aa)

WKVVNLLGSGGFGDVY
...   .||| |||.|
YRIGRKIGSGSFGDIY