Gene T07A9.3 (Nematode worm)

T07A9.3

Species: Nematode worm
Alias: aSWK194, CE29466, T07A9.3
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: IV:-25.1, WormBase Physical Map location: IV: 408886-405683

Classification

Group: CMGC
Family: MAPK
Subfamily: JNK

Sequence

Name Sequence Type Origin Length Description Download
T07A9.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 301 Kinase domain by global Sugen HMM Fasta, JSON
T07A9.3.AA Protein Genbank 390 None Fasta, JSON

Protein domain

Protein domains of T07A9.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase T07A9.3.AA JNK 38-338 56 5.2e-225 753.79 In-house 1-309 (309) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-309/309
Sequence Identity: 56% (176 aa)

YVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQP--FVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHR--
|.||.|...||||.|.||.|.||.||||||||..|  |...|..||||||||....|.|.|||...|.|||...|..|..||.|||.|..||..|||.  
YQNLKFIGQGAQGIVCMAFDQVTNQRVAIKKMMRPDNFQNWMHWKRAYREFICMKCINHKNIIKMYNCFTPQETLEEFQDVYIVMEYMDWNLCQVIHSTF

LRLDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILGLP--YSEKVDIWSVGCIFA
..|||...|...||..|.|||||..|.|||||||||||||..|.||..|||.||.....  ..|..|||||||||||||.|..  |.|.|||||||||.|
MELDHERMSYLFYQMCCGIKHLHSMGIIHRDLKPSNIVVNQDCTLKICDFGHARTEDPT--FMMTPYVVTRYYRAPEVICGMMDNYKENVDIWSVGCIMA

EMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQSAAMYVRSL---PRHQARAFSEIVPDTNFLP-ETENPRVHLTPHVARDLLFNMLKINPEERY
|||.|.|||||||.||||.||...|||||.||..|.......||...   |..|...|.|..|||.|.. ....|..|||.|.||||||.||.|||..|.
EMIRHHVLFPGKDHIDQWNKIIEFLGTPDPHFMMQMQPHVRNYVENRNMDPYYQPYNFHEHFPDTLFPDVMQSEPKDHLTCHMARDLLFRMLVINPDDRI

SVEDALNHPYV
||.|||.|||.
SVDDALQHPYI
Kinase T07A9.3.AA MAPK 38-338 41 1.8e-164 552.7 In-house 1-328 (328) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-328/328
Sequence Identity: 41% (140 aa)

YVNLSFLNAGAQGTVVMADDLVTTQR------VAIKKMQQPFVMTMSAKRAYREFILLTTI-KHPNIIRLLNAFTPD-----TSLSTFREVYLVMELMTH
|..|...  ||.|.|..|.|  |.|.      |||||...||  ....||.||| .||  . .|.|||.||. |||.      ||. |...|.||||| .
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NLHEVIHRLR-LDHKTLSFFVYQSLCA--IKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTS-------------MRMSDYVVTRYYRAP
.|| .|.. . |...  ..|.|| |..  .|..|  .|||||||||||.||  | ||..||||||.   ...             | |..||.||.||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EVILG---LPYSEKVDIWSVGCIFAEMIN-HTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLG--QSAAMYVRSL---PRHQARAFSEIVPDTNFLPETE
|..|.     |...||.||||||||||.. ...|||||| ||||..| .|||||...||....  ..|. |..||   |..... .... |..||     
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF-----

NPRVHLTPHVARDLLFNMLKINPEERYSVEDALNHPYV
     .. . |.|||. || ..|..|..||.||.|||.
-----NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase T07A9.3.AA CMGC 38-338 23 1e-121 401.99 In-house 1-513 (513) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-513/513
Sequence Identity: 23% (120 aa)

YVNLSFLNAGAQGTVVMADDLVTTQR--------------VAIKKMQQPFVMTMSAK----------RAYREFILLTTIK-----------------HPN
| ... .  |. |.|. . |  | |.              |||||. .|| ..  ||          ||.||  .|  ..                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIRLLNAFTPDTSLST-----------FREVYLVMELMTHNLHEVIHRLR----------LDHKT------------LSFFV------YQSLCAIK--HL
|..|.. |... | ..           |...|||.|.| |.|...|.. .          |..                .|.      || |...|  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HNSG--VIHRDLKPSNIVVNDRCVL--------------------KVLDFGLARKKNVD--------------------TSMRMSDYVVTRYYRAPEVIL
|  .  .|||||||.|| .|..| |                    |. ||||||. ..                     ... ...|||||.|||||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GLP----------YSEKVDIWSVGCIFAEMIN--------HTVLFP-----------GKDRIDQWTKIYSVLGTP----------------DDHFISQLG
| .          |....|.||||||||||..        .  |||           ||. |||. ||  |||||                .. ... ..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

---------------------QSAAMYVRS---LPRHQARAFSEIVPDTNFLPETENPR-----------------------VHLTPHVARDLLFNMLKI
                      .|  |..|   .|... . .....|. ... . . ..                        .. .. |.||| .||..
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-N-NKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

NPEERYSVEDALNHPYV
.|..| ..|.||.||| 
DPDKRITAEQALQHPYF
Kinase T07A9.3.AA p38 38-338 42 2.5e-110 372.82 In-house 1-289 (289) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-289/289
Sequence Identity: 42% (131 aa)

YVNLSFLNAGAQGTVVMADDLVTTQR---VAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTP-DTSLSTFREVYLVMELMTHNLHEVIHR
|.||...  || |.|  | |  | |.   |||||.  ||  .. |||.|||  || ...| |.| ||. ||| ..|.. |..||.|...|   |. ..  
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

LRLDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILG-LPYSEKVDIWSVGCIFAE
 ||      | ||| | . |  |  |.|||||||||| ||..| |..|||||||     .   | .||.|| |||||..|    | ..||||||||| ||
QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR----HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAE

MINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQSAA-MYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYSVED
.|   .||||.| ||| ..| .|.||||. |.. . . .|  |..|.| .. | |... .  | .              | |||  ||.. |. | ..|.
LITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQ--------------AIDLLEKMLELDPDKRITAEE

ALNHPYV
|. ||| 
AMQHPYF
Kinase T07A9.3.AA ERK 38-338 37 1.2e-90 307.41 In-house 1-307 (307) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-307/307
Sequence Identity: 37% (121 aa)

YVNLSFLNAGAQGTVVMADDLV-----TTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIK-HPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVI
|  ....  || |.|. | |       | |.||||| ...|  .  .||..||  ||   | |.||| |.. . |. .   . ..|.| |||.  || .|
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE-QYNDIYCVEELMETDLHQII

HRL-RLDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMR-------MSDYVVTRYYRAPEVILGL-PYSEKVD
.   .|  .   .|.|| ||..|..| ..||||||||||| ||  |.||. ||||||. ... . .       |..||.||.|||||..| . .|....|
NSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMD

IWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTP--DDHFISQLGQSAAMYVRSLPR--HQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNM
|||.|||||||.. . |||||| ..| . | ...|||  .. .. .  . |  |...||    ... ...| |..|              . | |||  |
IWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNAN------------CNPQAIDLLEKM

LKINPEERYSVEDALNHPYV
| ..|..|..||..| ||| 
LVFDPDKRITVEECLEHPYF
Kinase T07A9.3.AA S_TKc 38-338 24 5.7e-82 279.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-231/231
Sequence Identity: 24% (79 aa)

YVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTH---NLHEVIHRL
|  |  .  || |.|  . .  | ..||||..          ....||  .|   .||||..|. .|          ..|.|||.. .   .|...|.. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKR

R-------LDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILGLPYSE-KVDIWSV
.       ..  .  |..|| .||....|. |.|||||||.|| ...  ..|. ||||||.         . ...|..|.||||.   .|.  |.|.||.
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQSAAMYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEER
|||..||.    .||      |  ... ..|                                                  .. |.|.. ..|. .||.|
GCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------------------------SPEAKDFIRKCLQKDPEKR

YSVEDALN-------HPYV
... .||.       ||..
PTA-EALQDEWDIKCHPWF
Kinase T07A9.3.AA Pkinase 38-338 26 1.2e-77 269.07 Pfam 1-293 (293) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-293/293
Sequence Identity: 26% (85 aa)

YVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYR--EFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTH-----NLHEV
|. .. . .|. |.|  . .  | ..||.|..  .       ... |  |  ..  ..||||.||. .|.        ...|.|||.. .      |...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY

IH---RLRL--DHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVL----KVLDFGLARKK-NVDTSMRMSDYVVTRYYRAPEVIL-GLPYSE
|.   . ..  . ... |..|| |......|. |.|||||||.|| .......    |. |||||... .   |  |.....|..|.|||||. | .|. 
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGP

KVDIWSVGCIFAEMINHTVLFPGK----DRIDQWTKIYSVLGTPDDHFISQLGQ-SAAMYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDL
|||.||.|||..||..   .|||.    . .||  .|. ..|.| .  ....   |  . .|  . |                . . .. |...  ..|.
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------------F-HWTF-HNWSEECKDF

LFNMLKINPEERYSVEDALNHPYV
. ..|. .|..|.. |..|.||..
IKWCLCKDPKKRPTAEQILQHPWF
Kinase T07A9.3.AA ERK5 38-338 37 4.5e-75 255.71 In-house 1-295 (295) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-295/295
Sequence Identity: 37% (116 aa)

YVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHR---L
|  .  .  || | |  |    . |.|||||.   |     ||| .||  .|   .| ||| . .   |   .| ...|| |..||   || .||    .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPF

RLDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNV----DTSMRMSDYVVTRYYRAPEVILGLP-YSEKVDIWSVGCI
 |.|  . .|.|| |  .| .|   ||||||||||..||. | ||. |||.||        .  | | .|| ||.|||||... .  |   .|.||||||
TLEH--IRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCI

FAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLG-QSAAMYVRS-LPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERY
| |||    .||||  |.|   |  |||.|  | |   . .    |. . .| .| . .... |                   | |||  ||.  | || 
FGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKAD--------------RQALDLLARMLRFEPSERI

SVEDALNHPYV
.|  || ||..
TVNKALQHPFL
Kinase T07A9.3.AA ERK1 38-338 39 5.5e-70 238.82 In-house 1-289 (289) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-289/289
Sequence Identity: 39% (121 aa)

YVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHRLRLD
|.||...  || | |. |.| |. |||||||.  ||      .|  ||  .||  || ||| . .    || .  .|.||.| .||   |  ..   .| 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRADT-IEQMRDVYIVQCLMETDLYKLLKTQHLS

HKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLAR--KKNVDTSMRMSDYVVTRYYRAPEVIL-GLPYSEKVDIWSVGCIFAEMI
   . .|.|| |  .| .|   |.||||||||...|  | ||. ||||||    . |    . .|| ||.|||||..|    |   .|||||||| |||.
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML

NHTVLFPGKDRIDQWTKIYSVLGTP-DDHFISQLGQSAAMYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYSVEDAL
    .||||  .||  .| .||| |  |     . . |  |..|||  .  .. .. |..                 | |||  ||  ||..|  ||.||
SNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSK--------------ALDLLDKMLTFNPHKRITVEEAL

NHPYV
 |||.
AHPYL
Kinase T07A9.3.AA ERK7 38-338 36 8.6e-68 230.86 In-house 1-292 (292) Show / Hide 
Range on Protein: 38-338
Range on HMM: 1-292/292
Sequence Identity: 36% (114 aa)

YVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIK-HPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHRLR-
|  .. |  || | |  | |  | | ||.||.   |     | | .|| ..|  .. |||||||.| .  |      | .||| | |   || || . . 
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADND----RDIYLVFEFMETDLHAVIRKGNI

LDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLAR---KKN--VDTSMRMSDYVVTRYYRAPEVILG-LPYSEKVDIWSVGCI
|      . .|| | |||..|   ||||||||||| ..  |..|| ||||||   ...   .    . .|| || |||||. ||   |   || ||.|||
LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCI

FAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQSAAMYV-RSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYS
 .||.    .|||   ..|  ||  ... |    |  .| . |. .  ...... . .....|.              ... | ||| ..|  ||..| .
LGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQ--------------CCDDAIDLLKRLLVFNPKKRLT

VEDALNHPYV
.|.||.||||
AEQALQHPYV
Kinase T07A9.3.AA nmo 47-259 44 9.3e-68 207.23 In-house 10-223 (292) Show / Hide 
Range on Protein: 47-259
Range on HMM: 10-223/292
Sequence Identity: 44% (96 aa)

GAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVI---HRLRLDHKTLSF
|| | |    |    .|||.||| . |   .|.|| .||  .|   || |.. .|.   |   .. |.|.| | |||   || .|     |  ||  .  
GAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQP-PHKDFFQEIYVVTELMQSDLHKIIVSPQHLSSDH--VKV

FVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILGL-PYSEKVDIWSVGCIFAEMINHTVLFPG
|.|| |  .| ||  ...|||.|| |..||  ||||. |||||| .. |.|  |   ||| ||||||...|   |.. ||||||||||||..   .||  
FLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGRRILFQA

KDRIDQWTKIYSVLGTP
.  |.|   |  .||||
QSPIQQLQMITDLLGTP
Kinase T07A9.3.AA MAPK-Unclassified 38-187 35 9.8e-38 131.69 In-house 1-157 (575) Show / Hide 
Range on Protein: 38-187
Range on HMM: 1-157/575
Sequence Identity: 35% (56 aa)

YVNLSFLNAGAQGTVVMADDLVT-TQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTPDTSLS-TFREVYLVMELMTH---NLHEVIH
|     . .|| | |. | |  .  | |||||    |     .||. ||  .|  . |||||.. . |...  .   |  .|.||..|     .|| .|.
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

-RL-RLDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLAR
 ..  . |.    | || |  .| ||  ..|||||||||. .|  | ... |||..|
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase T07A9.3.AA MAPK-Unclassified 193-338 28 8.7e-36 125.22 In-house 401-575 (575) Show / Hide 
Range on Protein: 193-338
Range on HMM: 401-575/575
Sequence Identity: 28% (52 aa)

TSMRMSDYVVTRYYRAPEVILGLP-YSEKVDIWSVGCIFAEMIN-----------HTVLFPGKD--------------------RIDQWTKIYSVLGTPD
..  |. |||||.||||| .| .. |. .|||||.|||||||..           |  ||||.|                     .||   | ..||.|.
HCYHMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPP

DHFISQLGQSAAM-YVRSLPRHQARAFSEIVPDTNFLPETE-NPRVHLTPHVARDLLFNMLKINPEERYSVEDALNHPYV
   ..  ... |  |..|. .     |... .     ...  . ..      ..|..  || .||  |.. ..||.|||.
EEDCNFITCDSARKYIQSFKCKTPVHFTDLMF-----CKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase T07A9.3.AA TyrKc 38-341 19 7.4e-15 17.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 38-341
Range on HMM: 1-280/280
Sequence Identity: 19% (66 aa)

YVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTI--KHPNIIRLLNAFTPDTSLSTF---REVYLVMELMTH-NLHEVI
 . .  |  || |.|. .      . ||.|...         .  .||  ... .  .||||.||. . | .     |     ...|||.| | .|.. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYL

HRLR--LDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVD-------TSMRM-----SDYVVTRYYRAPEVILGLPY
.. |  | .|.|  | .|  |   .||  ..|||||   |. |... . |. ||||.|.   |          |.     .....     |||.|    .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SEKVDIWSVGCIFAEMINHTVLFPGK--------DRIDQWTKIYSVLGTPDD--HFISQLGQSAAMYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLT
..| |.|| |    |.       .          ... .. |    .  |..    .|                             |        |. .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS-----------------------------F--------VCCP

PHVARDLLFNMLKINPEERYSVEDALNHPYVKLW
. . . .     . .||.| . ..      ....
DEMYQ-IMKQCWHEDPEDRPTFSEI-----HECF
Kinase T07A9.3.AA Pkinase_Tyr 49-225 27 1.9e-13 46.2 Pfam 17-199 (270) Show / Hide 
Range on Protein: 49-225
Range on HMM: 17-199/270
Sequence Identity: 27% (53 aa)

QGTVVMADDLVTTQRVAIKKMQQPFVMTMS--AKRAYREFILLTTI-KHPNIIRLLNAFTPDTSLSTFREVYLVMELMTH-NLHEVIHRL-----RLDHK
.||  . |.  |.. ||.|..  .  |      .   ||  ..... .||||.||. . |..   .   ..|.|||.| | .|..  ..      .|..|
KGTWKG-DPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDYLRKHREDKQPLTMK

TLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDY-VVT-------RYYRAPEVILGLPYSEKVDIWS
.|  . .|  ..  .|.. . |||||   |. |..  | |. ||||||       .  . | ...       . . |||.|    ...| |.||
DLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-----YNDDYYYRKRGGGKLPIKWM-APECINYGKFTTKSDVWS
Kinase T07A9.3.AA nmo 309-338 50 3.4e-10 26.9 In-house 263-292 (292) Show / Hide 
Range on Protein: 309-338
Range on HMM: 263-292/292
Sequence Identity: 50% (15 aa)

HVARDLLFNMLKINPEERYSVEDALNHPYV
| | .||  ||  .|. | |..||| |||.
HEAVHLLCRMLHFDPDKRISCKDALAHPYL