Gene T07F12.4 (Nematode worm)

T07F12.4

Species: Nematode worm
Alias: T07F12.4, CE28650, aSWK246
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: X:-6.64, WormBase Physical Map location: X: 4901931-4900449,

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
T07F12.4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 230 Kinase domain by global Sugen HMM Fasta, JSON
T07F12.4.AA Protein Genbank 288 None Fasta, JSON

Protein domain

Protein domains of T07F12.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase T07F12.4.AA ULK 20-282 23 1.7e-70 240.48 In-house 2-324 (324) Show / Hide 
Range on Protein: 20-282
Range on HMM: 2-324/324
Sequence Identity: 23% (76 aa)

SVDAMIGMGAFG-AVFKGSLKDS---SNSIAIKRML-----KVHVK----------ESELKMIKELN---SEY--LVGVLDICNFDDF-FCCLIMELCDC
... ..| |.||  |.||  |..      .|.| .      |   .          ..| . .|.|.   ...   |  .|... ... ....|||.|..
CLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNG

-DLDHHMRNIS------VKGRLNPSNFRLLLDNIARGYKALYELKIVHRDIKPQNILITYTDAS-------KQIACARITDFGISRTLDNEGEELCNVA-
 ||.. . .         |.||. .  .  .  |. |.|.|.. .|.|||||||||||.  ...       . . .. |.||| ....||...| .    
GDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTFYYMAPEVGANLLKTCQYD-SKVDMWSIGCLLYQCVTGEVPFDECSLCKLFLY--------------VAGANFDAYDPPELPDELSQEVS
        || .||||..  .... ..|. .|.|.||.||..|....|..|| ..  ....||              .   ... ..||   . .|.|. 
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPECK

GIIQSLLQLDTTQRCTPTQFYDKAIN
 .|. .|| | ..|.. .....  . 
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase T07F12.4.AA ULK 20-282 22 2.7e-67 229.86 In-house 2-329 (329) Show / Hide 
Range on Protein: 20-282
Range on HMM: 2-329/329
Sequence Identity: 22% (74 aa)

SVDAMIGMGAFGAVFKGSLKDS----SNSIAIKRML---KVHVK------------ESELKMIKELN----SEY----LVGVLDICNFDDF-FCCLIMEL
... ..| |.|| |.||  |..       .|.| ..   .   .            ..| | .|.|.    ...     |  .|... ...  . .|||.
CLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEY

CDC-DLDHHMRNIS-------VKGRLNPSNFRLLLDNIARGYKALYELKIVHRDIKPQNILITYTDAS-------KQIACARITDFGISRTLDNE---GE
|.  ||.. . .          |.||. .  .  .  |. |.|.|.. .|.|||||||||||.  ...       . . .. |.||| ....||.    .
CNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDNMEQQ

ELCNVA------GTFYYMAPEVGANLLKTCQYD-SKVDMWSIGCLLYQCVTGEVPFDECSLCKLFLYVAGANFDA---------YDPPELP-----DELS
 ..         || .||||..  .... ..|. .|.|.||.||..|....|..|| ..  ....|.    ...            |.. |     . .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

QEVSGIIQSLLQLDTTQRCTPTQFYDKAIN
.|.  .|. .|| | ..|.. .....  . 
PECKDLIRRMLQYDEKDRISWEELFNHPWF
S_TKc T07F12.4.AA S_TKc 19-284 25 3.7e-53 183.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-284
Range on HMM: 1-231/231
Sequence Identity: 25% (71 aa)

DSVDAMIGMGAFGAVFKGSLKDSSNSIAIKRMLKVHVKESELKMIKELNSEYLVGVLDICNFDDFFCCLIMELCDC---DLDHHMRNISVKGR---LNPS
  .   || |||| |.|.  |..    |||..      ..|... |. . ...|  .|..     . ...||.||    || .....   .|.   ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

NFRLLLDNIARGYKALYELKIVHRDIKPQNILITYTDASKQIACARITDFGISRTLDNEGEELCNVAGTFYYMAPEVGANLLKTCQYDS-KVDMWSIGCL
  | ..  |... . . ...|.|||.||.|||..         .  |.|||..| |         . || .||||||        .|.  |.|.||.||.
HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL-------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCI

LYQCVTGEVPFDECSLCKLFLYVAGANFDAYDPPELPDELSQEVSGIIQSLLQLDTTQRCTPTQFYD-----KAINWS
|| ...|. ||.   . ..|  .                 |.|.  .|. .|| | ..| |  .        |.  | 
LYEMLCGYPPFP--QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase T07F12.4.AA Pkinase 25-275 26 1.1e-51 182.79 Pfam 7-286 (293) Show / Hide 
Range on Protein: 25-275
Range on HMM: 7-286/293
Sequence Identity: 26% (77 aa)

IGMGAFGAVFKGSLKDSSNSIAIKRMLKVHVKE---------SELKMIKELNSEYLVGVLDICNFDDFFCCLIMELCDC-----DLDHHMRNISVKGRL-
|| |.|| |.|.  |...   |.|.. |.| |.         ||... |.||... |  .|..  .|  . ..||.|..     || ....  . .|.. 
IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYIST-WRHGCFY

-NPSNFRLLLDNIARGYKALYELKIVHRDIKPQNILIT---YTDASKQIACARITDFGISRTL-DNEGEELCNVAGTFYYMAPEVGANLLKTCQYDSKVD
  .   .  .  |.|| . ... .|.|||.||.||||    ..||     | .|.|||... .    .. .  ..|| .||||||   ...   |..|||
FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-----CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV---IRGGQYYGPKVD

MWSIGCLLYQCVTGEVPFDEC----SLCKLFLYVAGANFDAYDPPELPDELS-----------------QEVSGIIQSLLQLDTTQRCTPTQ
|||.||.||. ..|. ||...    .........     .   . . ... |                 .|   .| ..|..| ..|.|..|
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ
Kinase T07F12.4.AA CAMK 24-275 17 5.5e-39 122.76 In-house 1-418 (425) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-418/425
Sequence Identity: 17% (74 aa)

MIGMGAFGAVFKGSLKDSS------------NSIAIKRMLKVHVK---------------------------------ESELKMIKE-------LNSEYL
 .| |.|| |...  | .                ||| . |  .|                                 ..|... |        |. . .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VGVLDICNFDDF------------------FCCLIM---ELCDCD------LDHHMRN------------ISVKGRLNPSNFRLLLDNIARGYKALYELK
.  ...   ...                  .....|   |.|.        .|.  ..            .  .||.. .  | .   |. . . . ...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKPQNILITYTDASKQI-----------ACARITDFGISRTLDN-----------------------EGEELCNVAGTFYYMA-PEVGAN-----
|||||.|| |||... . ...            .   |.||| .. .|                        ||. .  . || .||| |||        
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----LLKTCQYDSKVDMWSIGCLLYQCVTGEVPFDEC-------------SLCKLFLYVAGANFDAYDPP----------ELPDELSQE--------VS
     . .   |. |.||||.|..|| ...|. ||..              .. .||  .  ...| ..|.          |  |. |.|        . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

GIIQSLLQLDTTQRCTPTQ
  |...|| | ..| | .|
DLIRKMLQVDPEKRMTIEQ
Kinase T07F12.4.AA Ciliate-E2 19-275 19 1.1e-37 126.9 In-house 1-358 (365) Show / Hide 
Range on Protein: 19-275
Range on HMM: 1-358/365
Sequence Identity: 19% (76 aa)

DSVDAMIGMGAFGAVFKGSL-----------------------KDSSNSIAIKRMLK--VHVKESELKMIKELN----------------SEYLVGVLDI
  .  .|| |.|| |.|..                        |. .. .|.|.| |  .  ...|.....|.|                . ...   . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CNF-DDFFCCLIMELCDC-DLDHHMRNISVK--------GRLNPSNFRLLLDNIARGY---------------KALYELK-IVHRDIKPQNILITYTDAS
    ||  . |.||.|.  || ....| . |        ....    . .   |..|.               . | . . |.||||||.|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

KQIACARITDFGISRTLDNEGEE-----LCN--------------------------VAGTFYYMAPEVGANLLKTCQ---------YDSKVDMWSIGCL
       |.|||.|. .|.. ..     .|.                          ..|| .|||||.    |.  .         || |.|.||.|..
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEI----LNGKKYDNQQKQKGYDYKCDIWSLGVI

LYQCVTGEVPFDECSLCKLFLYVAGANFDAYDPPELP------------------DELSQEVSGIIQS----LLQLDTTQRCT-PTQ
||....|. ||               .     . ..|                  ...|||.  .|.     .|| |  .| | . |
LYEMLFGKPPF--------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQ
Kinase T07F12.4.AA AGC 130-270 19 1e-34 85.92 In-house 171-373 (395) Show / Hide 
Range on Protein: 130-270
Range on HMM: 171-373/395
Sequence Identity: 19% (43 aa)

E-LKIVHRD-IKPQNILITYTDASKQIACARITDFGISRTLDNEG-------------------------------------------------EELCN-
. ..|.||| .|| |||..           ..|||| .  . |.|                                                 ..... 
SHMGIIHRDYLKPENILLDED------GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWT

VAG--TFYYMAPEVGANLLKTCQYDSKVDMWS--IGCLLYQCVTGEVPFDECSLC----------KLFLYVAGANFDAYDPPELP----------DELSQ
  |  |  |||||.         |.  .| ||   |||.|. .||  ||   .            ..|  .   ..   .....|          ...|.
FCGPCTPEYMAPEIL--------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSP

EVSGIIQSLLQLDTTQR
|   .|. ||. | ..|
EAKDLIKKLLCKDPEKR
Kinase T07F12.4.AA CMGC 20-213 18 1.6e-34 110.19 In-house 2-326 (513) Show / Hide 
Range on Protein: 20-213
Range on HMM: 2-326/513
Sequence Identity: 18% (60 aa)

SVDAMIGMGAFGAVFKGSLKDSSNS--------------IAIKRMLKVHVKE-----------------SELKMIKELN-----------------SEYL
 ..  || |..| |.|.  |..                 .|||.. ... .|                  |.|. |.||                  ...
EIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VGVLDICNFDDF----------------FCCLIMELCDCDLDHHMRNIS--VKG----RLNPSN------------FRLLL------DNIARG--YKALY
|. .||. ...                   .|..|..|.|| . ..| .   .|     |..               . ..        | ||   | . 
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

ELK--IVHRDIKPQNILITYTDAS--------------KQIACARITDFGISRTLDNE---------------------GEELCNVAGTFYYMAPEVGAN
  .  |.|||.||.||||. .  .              ..  . .| ||| .| ....                     .. . .   | .| |||.   
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI---

LLKTCQYD---------SKVDMWSIGCLLY
||   .|.         ...||||.|| ..
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFA
Kinase T07F12.4.AA STE 24-275 21 1.4e-33 116.03 In-house 6-350 (359) Show / Hide 
Range on Protein: 24-275
Range on HMM: 6-350/359
Sequence Identity: 21% (75 aa)

MIGMGAFGAVFKGSLK------DSSNS---------IAIKRML----------------------KVHVKESELKMIKELN--SEYLVGVLDICNFD---
.|| |||| |.|.  .      .. .          .|||.|                       ..   . |.|. |..|  ... |  .. .  .   
KIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHN

---DFFCCLIMELCDC-DLDHHMRNISVKGRLNP-----------SNFRLLLDNIARG-YKALYELKIVHRDIKPQNILITYTDASKQIACARITDFGIS
   |  ....||..|   ||  ...   .|. ..           |  .  .  | .|  . | ...|.||||||.|||.           . ..|||..
HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----------VKLCDFGVC

RTLDNE----------------GEELCNVAGTFYYMAPEVGANLLKT--CQYDSKVDMWSIGCLLYQCVTGEVPFDECSLCK-LFLYVAGANFDA-----
  |...                ...   ..||  .|||||  .  ..   .|| |.|.||.||..   .||..|. . .  . .|.   .    .     
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----YDPPELPD-------------------ELSQEVSGIIQSLLQLDTTQRCTPTQ
     .|| |||                   ..|.|    |.  || |  .| |..|
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase T07F12.4.AA TKL 25-224 20 9.9e-33 115.06 In-house 1-291 (364) Show / Hide 
Range on Protein: 25-224
Range on HMM: 1-291/364
Sequence Identity: 20% (63 aa)

IGMGAFGAVFKGSLKDSS--------NSIAIKRMLKVHV--------------------------------KESELKMIKELNSEYLVGVLDICNFDDF-
|| |.|| |.|| ..  .        . .|.|.. . ..                                .| |..|.. |. . .|  . .|.  .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

--------F---CCLIMELCDC-DLDHHMRNISVKGRLNPSNFRLLLDNIARGYKALYELK--------IVHRDIKPQNILIT--YTDASKQIA------
            .|..||.|.. .| |..          .  .|. || ||||   |   .        |.|||.|..|||.   .|. |  .       
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALD-IARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS-NYMYNPNAD

-CARITDFGISRTLDNEGE-------------------ELCNVAGTFYYMAPEVGANLLKTC------------QYDSKVDMWSIGCLLYQCVTGEVPFD
 |. |.|||.||.....|.                    .... ||...|||||  . ....            .|. |.|..| | .|. ..|...|..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

E
.
D
Kinase T07F12.4.AA Ciliate-E2-Unclassified 25-223 21 4.7e-32 108.49 In-house 7-271 (352) Show / Hide 
Range on Protein: 25-223
Range on HMM: 7-271/352
Sequence Identity: 21% (60 aa)

IGMGAFGAVFKGSLKDSSNSI-AIKRMLKVHVKESELKM-----------IKELNSEYLVG-------------------VLDICNFDDFFCCLIMELC-
|| |.|| |.|   |.    . |.| | |.... . ..|           ...... | .                    ..  |  |.. ....||.| 
IGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCE

DCDLDHHMRNISV--------------KGRLNPSNFR-----LLLDNIARGY-KALYELKIVHRDIKPQNILITYTDASKQIACARITDFGISRTLDNE-
. ||  .... .               . ..   . .      ..  |  |  .  ....|.||||||.|||..         . .|.|||||. ...  
GGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK---NYYIKIIDFGISKKYQQNN

--------------GEELCNVAGTFYYM----APEVGANLLKTCQYD----SKVDMWSIGCLLYQCVTGEVPFD
               .... ..|| .||    ||||    |. ..||     |.|.|| |..||....|. ||.
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEV----LQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFY
Kinase T07F12.4.AA NEK 130-270 32 9.1e-25 84.41 In-house 132-274 (286) Show / Hide 
Range on Protein: 130-270
Range on HMM: 132-274/286
Sequence Identity: 32% (50 aa)

EL-----KIVHRDIKPQNILITYTDA-SKQIACARITDFGISRTLDNEGEELCN-VAGTFYYMAPEVGANLLKTCQYDSKVDMWSIGCLLYQCVTGEV--
.      ||.||||||||| .|  .  .     ..| |||||. |... . ..  . || |||.|||    ..   |..|.|.||.||.||. .|     
DRKGPQRKILHRDIKPQNIFLTKNNNDY---HNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEV----CQNKPYNNKSDIWSLGCVLYEMCTLKPKH

PFDEC--SLCKLFLYVAGANFDAYDPPELPDE--LSQEVSGIIQSLLQLDTTQR
||.    ..  |.. .        ..| .|.    ||. . .|...|| | .||
PFEAWDMNMPSLYMKIMKG----PQYPPIPSHRMYSQDLQNLISQMLQKDPEQR
Kinase T07F12.4.AA TyrKc 19-280 19 2.2e-13 -6.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-280
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

DSVDAMIGMGAFGAVFKGSLKDSSNSIAIKRMLKVHVKE---SELKMIKEL--NSEYLVGVLDICNFD-------DFFCCLIMELCDC-DLDHHMRNISV
 . . ..| |||| |.|| .|      |.| . . . .|   .|... ..|  . . .|  . .|  .       .   ...||...  ||... |.   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL-MIVMEYMPHGDLKDYLRKHRP

KGRLNPSNFRLLLDNIARGYKALYELKIVHRDIKPQNILITYTDASKQIACARITDFGISRTLDNE------GEELC-----NVA--GTFYYMAPEVGAN
|  |... .      ||.|   | . ...|||.   |.|..         ...|.||| || ....      ..        .         ||||.   
K--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC---

LLKTCQYDSKVDMWSIGCLLYQCVT-GEVPFDE-----CSLCKLFLYVAGANFDAYDPPELPDE--------LSQEVSGIIQSLLQLDTTQRCTPTQFYD
 .... . .| | || | ...   | |. |  .     .|   .. ||   .      .. |..         ..|.  |...  . |  .|.| .. ..
-INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYR-----MPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

KA
. 
CF
Kinase T07F12.4.AA AGC 20-69 24 0.01148 1.12 In-house 2-58 (395) Show / Hide 
Range on Protein: 20-69
Range on HMM: 2-58/395
Sequence Identity: 24% (14 aa)

SVDAMIGMGAFGAVFKGSLKD-----SSNSI-AIKRMLKVH-VKESELKMIKELNSE
 .  .|| |.|| |.    ||     ... . |.| . | | ... . .|..  ..|
EFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTE
Kinase T07F12.4.AA NEK 24-50 28 0.157256 1.63 In-house 6-37 (286) Show / Hide 
Range on Protein: 24-50
Range on HMM: 6-37/286
Sequence Identity: 28% (9 aa)

MIGMGAFGAVFKGSLKDSSNS-----IAIKRM
.|| |.|| |.|   |  ..       ..|..
KIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKI