Gene KSS1 (Bakers Yeast)

KSS1

Species: Bakers Yeast
Alias: KSS1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK1

Sequence

Name Sequence Type Origin Length Description Download
KSS1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 301 Kinase domain by global Sugen HMM Fasta, JSON
KSS1.AA Protein Refseq_NP 368 Recovery from alpha factor arrest; Kss1p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of KSS1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase KSS1.AA ERK 13-313 59 2e-221 741.89 In-house 1-307 (307) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-307/307
Sequence Identity: 59% (184 aa)

YKLVDLIGEGAYGTVCSAIHKP-----SGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVIN
|.....||.||||.|||||.|.     .| ||||||| ..|.......||.|||||||.|..|||||...| ..|.|....| .|.|||||||||...||
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

NQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLA-SSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTT
.|.    .|||||.|||.||||..|| ||||.|||||.||||.|.|||||||.||||||||.. |.... |....||||||||||||||||||..|.||.
SQQ----ELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTK

AMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTP-SFEDFNQIKSKRAKEYIANLPM--RPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRI
||||||||||.|||. .||||||.||.||...|....||| |.||...|.|..|..|| |||.  ||| |||........||..||||.|||.|.|||||
AMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRI

SAAEALRHPYL
...|.|.|||.
TVEECLEHPYF
Kinase KSS1.AA MAPK 13-313 53 8.60000000001e-194 650.09 In-house 1-328 (328) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-328/328
Sequence Identity: 53% (177 aa)

YKLVDLIGEGAYGTVCSAIHKP------SGIKVAIKKIQ-PFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRP------VSIDKLNAVYLVEELMET
|...  ||.||||.|||||.|.      .| |||||||. ||.....  ||.|||||||.||.|||||..||  .|       |....| .|.|.|||||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLQKVINNQNSGFSTLSDDHVQYFTYQILRA--LKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLAS-SSDSRETLVG------FMTEYVATRW
||...|. |.    .|||||.|||.|||||.  || ||||.|||||.||||.|.|.|||||.|||||||.... ...  ..  .      .|||||||||
DLHQIIKSQQ----PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRW

YRAPEIMLT--FQEYTTAMDIWSCGCILAEMVS-GKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIK-SKRAKEYIANL---PMRPPLPWETVWSKTD--
||||||||    ..||.|.|.||.|||.|||.. .||||||.|| .|..||.||||||| |. ..|. |..|..|| .|   |..|. |||.......  
YRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFN

LNPDMIDLLDKMLQFNPDKRISAAEALRHPYL
 ||. ||||.|||.|.|||||...|||.|||.
ANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase KSS1.AA CMGC 13-313 28 1.3e-141 468.59 In-house 1-513 (513) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-513/513
Sequence Identity: 28% (147 aa)

YKLVDLIGEGAYGTVCSAIHKPSGIK--------------VAIKKIQ-PFSKKLFVT----------RTIREIKLLRYFH----------------EHEN
|. .. ||||.||.|.....| .. |              ||||||  || ..              |..||||.|....                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IISILDKVRPVS-------------IDKLNAVYLVEELMETDLQKVINNQNS-----GFSTLSDDH------------VQYFT------YQILRALK--S
|....| ...               . ..| .||| |.|..|| ..| |..      .   ||. |            ..||.      |||||.||   
IVKLYDIFYHKNSDGNEYEDKHIISQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

IHSAQ--VIHRDIKPSNLLLNSNCDL--------------------KVCDFGLARCLASSSDSRETLVGF--------------MTEYVATRWYRAPEIM
.||.   .||||.||.|.|.|.||.|                    |.||||||| . . || ... ...              .|.||.|||||||||.
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LTF---------QEYTTAMDIWSCGCILAEMVSG--------KPLFP-----------GRDYHHQLWLILEVLGTP----------------SFEDFNQI
|           ..|||..|.||.|||.|||. |        |||||           |... .|| .| .|||||                . |..| |
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

K--------------------SKRAKEYIAN---LPMRPPLPWETVWSKTD---------------------------------LNPDMIDLLDKMLQFN
|                    |. |. || .   .|..|| ||. .  . .                                 ..|. ||||.||||..
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PDKRISAAEALRHPYL
|||||.|..||.|||.
PDKRITAEQALQHPYF
Kinase KSS1.AA ERK1 13-313 55 8.70000000001e-132 444.12 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-289/289
Sequence Identity: 55% (167 aa)

YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGF
|  .. ||||||| ||||. .  . .|||||| ||  . .  ||.||||.|  |. ||||| | | .|  .|...  ||.| .|||||| |..  |.   
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKISPFEHQTYCQRTLREIKILTRFK-HENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKTQH---

STLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSC
  || ||. || ||||| || |||| |.|||.||||||||  ||||.|||||||     .|      ||.||||||||||||||||  . || ..|||| 
--LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARI----ADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSV

GCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPY
|||||||.| .|.|||. |  || .|| ||| || .| | |  ..|..|.  ||..| .||. .. |.|  .  .||||||| |||.|||   ||| |||
GCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKAD--SKALDLLDKMLTFNPHKRITVEEALAHPY

L
|
L
Kinase KSS1.AA p38 13-313 46 4.7e-131 441.67 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-289/289
Sequence Identity: 46% (143 aa)

YKLVDLIGEGAYGTVCSAIHKPSGIK---VAIKKIQ-PFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRP--VSIDKLNAVYLVEELMETDLQKVIN
|. .  .|.||||.||.|. . .| |   |||||.  || . ..  || ||..||.  . |||.|..||   |   |.. .. ||.| ..|..||.... 
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

NQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTA
 |      |||||.|.  |||||.|| |||| .|||| ||||. .| .|.|.. ||||||    . |.       ||.||||||||||||||   .|| .
CQR-----LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR----HCDDE------MTGYVATRWYRAPEIMLNWMHYTQT

MDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAE
 |||| |||.||...|..|||| |. .||  |..|.|||. |  . |.|..|. || ..| .|    ..| ..   ||  ||||.|||.  |||||.|.|
VDIWSVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMG--ANPQAIDLLEKMLELDPDKRITAEE

ALRHPYL
|..|||.
AMQHPYF
Kinase KSS1.AA ERK5 13-313 47 6.6e-120 404.65 In-house 1-295 (295) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-295/295
Sequence Identity: 47% (146 aa)

YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRP-VSIDKLNAVYLVEELMETDLQKVINNQNS
|| .. ||.|||| ||||...  | .||||||   | .     ||.||.|.|| |. |.||| | | ..| | .  .  || | .||| || ..|  .  
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFR-HDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQ-

GFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLAS-SSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDI
    .. .|. || ||||| || .|||||||||.|||||| | ||.||. |||.|| |.  |.| ..    |||||||||||||||.|.  ..|| |.|.
---PFTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQM---FMTEYVATRWYRAPELMFSSHDYTQAIDV

WSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIAN-LPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEAL
|| |||. ||.. . .|||. | ||| ||..|||.|.      . . . . |.   .| | | .||.|. | |  .  .||| .|| | | .||....||
WSVGCIFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKAD--RQALDLLARMLRFEPSERITVNKAL

RHPYL
.||.|
QHPFL
Kinase KSS1.AA ERK7 13-313 45 9.40000000001e-111 374.25 In-house 1-292 (292) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-292/292
Sequence Identity: 45% (136 aa)

YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSG
|..   .| |||| |  |. | ..  ||.|||   |  .    || ||| .|. ||.|.|||.... .|    |    .||| | |||||  ||   |  
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIR---ADNDRDIYLVFEFMETDLHAVIRKGN--

FSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWS
   | | |.||  ||.|||.| .||..|||||.||||.||.|.| .||||||||| .|.  .  .   . .||||||||||||||.|  ..|| . | ||
--ILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEY-DEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWS

CGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHP
 ||||.||. |||.|||    .|. .|||... |. || . |.|. |   . ... ... . . .    .  .| |||| ..|.|||.||..| .||.||
IGCILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMP--QCCDDAIDLLKRLLVFNPKKRLTAEQALQHP

YL
| 
YV
Kinase KSS1.AA S_TKc 13-313 29 1.5e-99 337.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-231/231
Sequence Identity: 29% (93 aa)

YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMET---DLQKVINNQN
|.....||.||.|.|. ..|| .| .||||.|          ...|||..|.    |.||. ..|  .       . .|.| |....   || ..| ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRG

SGF--STLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTT-A
..   . ..  |.....|||..||. .|| ..||||.||.|.||..   .|.||||||| |              | .. |.||.|||..     |.. .
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL----GYGKCK

MDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAE
 |.|||||||.||..|.|.||      |. ......|                                        |...|...|.||..|.||..| |
CDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-E

ALR-------HPYL
||.       ||..
ALQDEWDIKCHPWF
Kinase KSS1.AA CDK 13-313 33 4.7e-95 304.57 In-house 1-284 (284) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-284/284
Sequence Identity: 33% (110 aa)

YKLVDLIGEGAYGTVCSAIHKPSG-----IKVAIKKIQ-PF-----SKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKL------NAVYLVEE
|. .. ||||.||.|  |..| .|       ||.|||          |  |   .||||.||.    |.||....| .   . |.       | .|.| |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

LMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCD-----LKVCDFGLARCLASSSDSRETLVGFMTEYVATRW
 |..|| |..              .. ...|.||.|  .||  ..|||.||.|.|.|.|       ||. ||||||   . ..     .  .|  | |.|
YMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLW

YRAPEIMLTFQEYT--TAMDIWSCGCILAEMVS---GKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPD
|||||. |  ..|.  |. |.||.|||.|||.    .||||||.  ..|| .| ...|||. ..   ...                              
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------

MIDLLDKMLQFNPDKRISAAEALRHPYL
  |||.|||...|.||||| .|| |||.
--DLLNKMLCYDPKKRISAEQALQHPYF
Kinase KSS1.AA Pkinase 13-313 30 3.2e-93 320.81 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-293/293
Sequence Identity: 30% (97 aa)

YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIR---EIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMET-----DLQKV
|...  ||.|..|.|. ..|| .|..||.|.|   ..|  . .| |   ||.... .  |.||. ..| ..       . .|.| |..|      ||  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDY

IN-NQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDL----KVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLT
|   .. .|. .|..... . |||||.|. .||  .||||.||.|.|...|...    |.||||||...       .   . || .. |.||.|||. ..
ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRG

FQEYTTAMDIWSCGCILAEMVSGKPLFPGR----DYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQ
 |.|... |.|||||||.||..|.|.|||.    . | |...| ...|.|  .|. .  |..  . .   . .     .  | .. ......|.....|.
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTFHNWSEECKDFIKWCLC

FNPDKRISAAEALRHPYL
..| ||..|...| ||..
KDPKKRPTAEQILQHPWF
Kinase KSS1.AA nmo 14-313 43 1.5e-92 284.86 In-house 2-292 (292) Show / Hide 
Range on Protein: 14-313
Range on HMM: 2-292/292
Sequence Identity: 43% (131 aa)

KLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGF
.    || ||.| | |     .| .||.||. . |   .   |  ||.|.| .| .|.|..| || ..|  .| .. .| | |||  || |.|       
QPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFF-KHDNVLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVSPQ---

STLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSC
  || |||. | ||||| || .|||...|||||| |||.|||| ||.|||||||      . .. .   ||. | | .||||||..  . || |.|||| 
-HLSSDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVW----EQDQSK--HMTQEVVTQYYRAPEILMGARHYTSAVDIWSV

GCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWE--TVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRH
||| ||..  . ||  .   .|| .| ..||||| ||  .     ||  .   |..||      |. |  . . . ..|| .|| |.||||||. .|| |
GCIFAELLGRRILFQAQSPIQQLQMITDLLGTPSMEDM-KYACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAH

PYL
|||
PYL
Kinase KSS1.AA MAPK-Unclassified 182-313 39 7.1e-58 198.58 In-house 405-575 (575) Show / Hide 
Range on Protein: 182-313
Range on HMM: 405-575/575
Sequence Identity: 39% (67 aa)

MTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSG-----------KPLFPGRD--------------------YHHQLWLILEVLGTPSFEDF
||.||.|||||||||||  .||.|. |||| |||.|||..            .|||||.|                    .  |. .|...||.|  || 
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC

NQIKSKRAKEYIANLPMRPPLPWE-TVWSKTD-------LNPDMIDLLDKMLQFNPDKRISAAEALRHPYL
| |.. .|..||  .   .|...     .|.         |.. ||...||||||| |||.| .|| ||| 
NFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase KSS1.AA MAPK-Unclassified 13-166 42 1.4e-53 184.37 In-house 1-157 (575) Show / Hide 
Range on Protein: 13-166
Range on HMM: 1-157/575
Sequence Identity: 42% (69 aa)

YKLVDLIGEGAYGTVCSAIHKPS-GIKVAIKKIQ-PFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDK--LNAVYLVEELMET---DLQKVI
| .  .|| |||| || |. | . . .|||||.   |  .    |. ||| .|||   |.||| | |  .. .        .|.| ..|.|   || ..|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLN-HPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQII

NNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLAR
    |   .... |.|||.||||| || .||| .|||| ||||||.| .| ...||||..|
---KSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase KSS1.AA TyrKc 13-313 19 2.8e-15 24.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYF-HEHENIISILDKVRPVSIDKL------NAVYLVEELMET-DLQKV
 .| . .||||.|.|. .. |   |.||.|.... .    .   .||..... .  .|.||. ..     | ...         ...| |.|.  ||.. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLY----GVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

I-NNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASS----SDSRETLVGF--MTEY-VATRWYRAPEI
. ....     |. ..  .| .|| .    .|| ..||||.   | |...|   |..||||.| . .       .    .     . . .  ||. ||| 
LRKHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APEC

MLTFQEYTTAMDIWSCGCILAEMVS-GKPLFPGR----DYHHQLWLILEVLGTPSFEDF----NQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMI
.  . ..||. |.|| |  . |. . |..  ||         ..   ..  . .   .                                .     ..| 
I-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------F-VCCPDEMY

DLLDKMLQFNPDKRISAAEALRHPYL
..  .  ...|..| . .|   | ..
QIMKQCWHEDPEDRPTFSEI--HECF
Kinase KSS1.AA Pkinase_Tyr 13-76 24 1.3e-07 26.4 Pfam 1-70 (270) Show / Hide 
Range on Protein: 13-76
Range on HMM: 1-70/270
Sequence Identity: 24% (17 aa)

YKLVDLIGEGAYGTVCSAIHK----PSGIKVAIKKIQPFSKKL--FVTRTIREIKLLRYFHEHENIISIL
 ..   .||||.|.|. .. |      .|.||.|.. . . .   .    .||.|... .  |.||.. .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY
Kinase KSS1.AA Pkinase_Tyr 148-221 31 0.119383 6.21 Pfam 141-209 (270) Show / Hide 
Range on Protein: 148-221
Range on HMM: 141-209/270
Sequence Identity: 31% (23 aa)

NLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVS
| |...|   |.||||||| .  . |   . ..  .  .  .|. ||| . .   .||. |.|| |  . |...
NCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGK-LPIKWM-APECINYGK-FTTKSDVWSFGVLMWEIFT