SLT2

Species: Bakers Yeast
Alias: SLT2
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK1

Sequence

Name Sequence Type Origin Length Description Download
SLT2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 296 Kinase domain by global Sugen HMM Fasta, JSON
SLT2.AA Protein Refseq_NP 484 Suppressor of lyt2; Slt2p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of SLT2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SLT2.AA ERK 23-318 60 3e-224 751.26 In-house 1-307 (307) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-307/307
Sequence Identity: 60% (185 aa)

FQLIKEIGHGAYGIVCSARFAE---AAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQII
.|.||.|||||||.||||.. |   ......|||||..|.|.....||| |||.||||||.||.||.||.|......|. ..|..|..|||||.|.||||
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE-QYNDIYCVEELMETDLHQII

KSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLAR----GYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAID
.| |.|.|.|.|.|.|||||||||||||.|.||||||.|.||| .|.||||||||||    .|.||...|..|.|||||||||||||||||.| ||||.|
NSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMD

VWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTP-PDETLRRIGSKNVQDYIHQLGF--IPKVPFVNLYPNAN--SQALDLLEQMLAFDPQKRITVD
.||.|||.||.||.||.|.|||||.|.|.|.|..||| ..|.|..|.|.|...||..|..  .|..|. |..||||  .||.||||.||.|||.|||||.
IWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVE

EALEHPYL
|.|||||.
ECLEHPYF

Kinase SLT2.AA MAPK 23-318 51 8.99999999999e-191 640.06 In-house 1-328 (328) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-328/328
Sequence Identity: 51% (168 aa)

FQLIKEIGHGAYGIVCSARFAE----AAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVF-----YPDGSINGLYLYEELMEC
.|..| ||.||||.||||.  .    . ....|||||. ..|.....||| .||.||||||..|.|| .|.|.   .     .. .. | .|...||||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DMHQIIKSGQPLTDAHYQSFTYQILCG--LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQ----------FLTEYVATRWYRAP
|.||||||.|||.| | |.|.||||.|  |||||||.|.||||||.|.||| .|.||||||||||.   .  .. |          ..||||||||||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EIMLS--YQGYTKAIDVWSAGCILAEFLG-GKPIFKGKDYVNQLNQILQVLGTPPDETLRRIG-SKNVQDYIHQL---GFIPKVPFVNLYPN----ANSQ
||||.  ...||||.|.||.|||.||.|. .||.|.||||..|.|.|..|||||..| ...|. |... .||..|      ||.|. ...||    ||.|
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

ALDLLEQMLAFDPQKRITVDEALEHPYL
|.||||.||.|||.|||||.|||.|||.
AIDLLEKMLVFDPDKRITVEEALQHPYF

Kinase SLT2.AA CMGC 23-318 27 5e-140 463.32 In-house 1-513 (513) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-513/513
Sequence Identity: 27% (144 aa)

FQLIKEIGHGAYGIVCSARFAE------------AAEDTTVAIKKVTNVFSKTLLCK----------RSLRELKLLRHFR----------------GHKN
.. || ||.|.||.|...|  .               .  |||||. |.| ..  .|          |.|||.|.|.|..                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ITCLYDMDIVFYPDGS-----------INGLYLYEELMECDMHQIIKSGQ---------PLTDAH------------YQSFT------YQILCGLK--YI
| .|||.     .||.            | |||  |.|..| .|.||. |         ||.. |             ..|.      ||||.|||  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAD--VLHRDLKPGNLLVNADCQL--------------------KICDFGLARGYSENPVE-----------------NSQFLTEYVATRWYRAPEIML
||..  ..|||||| |.|.| .|.|                    ||||||||| |.... .                 .....|.||.|||||||||.|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

SY---------QGYTKAIDVWSAGCILAEFLGG--------KPIFK-----------GKDYVNQLNQILQVLGTP----------------PDETLRRIG
..         ..||..||.||.|||.|| . |        ||.|.           ||....||..| .|||||                ..|   .|.
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

--------------------SKNVQDYIHQ---LGFIPKVPFVNLYPN-----------------------------------ANSQALDLLEQMLAFDP
                    |. .. ||..   .. .|. |. ||.|.                                   ...||.|||..|| .||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

QKRITVDEALEHPYL
.||||...||.|||.
DKRITAEQALQHPYF

Kinase SLT2.AA p38 23-318 45 6.4e-126 424.63 In-house 1-289 (289) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-289/289
Sequence Identity: 45% (136 aa)

FQLIKEIGHGAYGIVCSARFAEAAED-TTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYP----DGSINGLYLYEELMECDMHQ
.| .. .| |||| ||.|. ..  .    |||||    | ...  ||  |||.||.| | | |. || |   || |      ...  |.  ..|. | ..
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLD---VFTPPAHSMNDFQDVYMVTHFMGADLNN

IIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVW
|.|. . |.| | |   |||| ||||||||.. ||||||.|. || || |.| ||||||       .  . .|.||||||||||||||.   ||...|.|
IMKCQR-LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR-------HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIW

SAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPY
| |||.|| . |.. |.|.|...||..|..|.|||..| . .| |..   ||  .  .|.  | .....|| ||.|||| ||  || ||||. ||..|||
SVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPY

L
.
F

Kinase SLT2.AA ERK5 23-318 49 2.2e-124 419.53 In-house 1-295 (295) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-295/295
Sequence Identity: 49% (148 aa)

FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSG
.. | .|| ||||.|||||     .   |||||. | | .    || .||||.||||| | ||  . |.     | . .   |   .||| |.|||| | 
YKIIEKIGNGAYGVVCSARRRKNGQQ--VAIKKIPNAFDVVTNAKRTFRELKILRHFR-HDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSN

QPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSE-NPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGC
||.|  |   | |||| ||||.|||.|.|||||| |||||  | ||| |||.||| .   | .   |.|||||||||||||.|.| . ||.|||||| ||
QPFTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGC

ILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQ-LGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYL
|. | .. . .| || |..||. |..|||.||   .. ...  |. |. . .     ...  .|| |  |||||| .|| |.| .|||| .|| ||.|
IFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL

Kinase SLT2.AA ERK1 23-318 52 1e-115 390.74 In-house 1-289 (289) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-289/289
Sequence Identity: 52% (155 aa)

FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSG
.  .. ||.||||.||||   .  . . |||||.   |     |.| |||.|.|  |. | ||  . |. |      ..  .|.  .||| |. ...|. 
YTNLQYIGEGAYGMVCSA--YDTVHKQRVAIKKIS-PFEHQTYCQRTLREIKILTRFK-HENIINIQDI-IRADTIEQMRDVYIVQCLMETDLYKLLKT-

QPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCI
|.|   |   | |||| |||||||| |||||||| |||.|  | ||||||||||  ..   .   ||||||||||||||||||  .||||.||.|| |||
QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI

LAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYL
||| |  .||| || |. ||| || ||| |  . |. |  .    |.. | . ||||.  |.|.| |.|||||..||.| |.|||||.||| ||||
LAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL

Kinase SLT2.AA ERK7 23-318 41 5e-109 368.52 In-house 1-292 (292) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-292/292
Sequence Identity: 41% (123 aa)

FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSG
....| .| ||||||  |    . .  .||.||.   |       |  ||  .|. |..| ||  |..   |.  |     .||  | || |.| .|. |
YEIRKRLGKGAYGIVWKAYDKRTKQ--VVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLIN---VIRADNDRD-IYLVFEFMETDLHAVIRKG

QPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENP--VENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAG
. | | | |.  ||.|  .||.||..|.|||||| |.|....| .|.|||||||  .. .   |. . |||||||||||||||.|. . |||..| || |
NILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIG

CILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYL
|||.| | |||.| |   .||...||.... |  | .  |||.     ..|..  .. .. ...|..  .|.||| ..|.| |.||.|...||.||| 
CILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV

Kinase SLT2.AA nmo 23-318 42 5.4e-96 295.68 In-house 1-292 (292) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-292/292
Sequence Identity: 42% (128 aa)

FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDG-SINGLYLYEELMECDMHQIIKS
 |  . ||.||.|.| |    .  .   ||.||. |||   . |||  ||||.|  |. | |   |  .||.  |.    . .|   |||  |.|.|| |
IQPDRPIGYGAFGVVWS--VTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFK-HDN--VLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVS

GQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGC
 |.|.  | . | |||| ||||.|||..||||.||||||||..| ||||||||||   .   ..|. .|. | | .||||||..  . || |.|.|| ||
PQHLSSDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQ---DQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGC

ILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPN---ANSQALDLLEQMLAFDPQKRITVDEALEHPYL
| || || . .|. .  ..||. | ..||||  | ..       .  . .    |... .        |.  | .|| .|| |||.||| . .||.||||
IFAELLGRRILFQAQSPIQQLQMITDLLGTPSMEDMKYACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL





Kinase SLT2.AA S_TKc 23-318 28 2.9e-93 317.08 SMART 1-231 (231) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-231/231
Sequence Identity: 28% (89 aa)

FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMEC---DMHQII
......||.||.| |. .|  .   .  ||||..          .. .||...|..  .|.||  |||.          . ||.  |...    |....|
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYI

KSGQP------LTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTK-
|. ..      ..  | ....|||.|.|.|.||  ..|||||| |.|..   ..||||||||| .           | .. |.||.|||..    ||.| 
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----GYGKC

AIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEA
..|.|| ||||.|.| |.| |       |........|                                      ..|.|.....| .||.||.|. ||
KCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA

LE-------HPYL
|.       ||..
LQDEWDIKCHPWF

Kinase SLT2.AA CDK 23-318 31 3.4e-92 295.26 In-house 1-284 (284) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-284/284
Sequence Identity: 31% (102 aa)

FQLIKEIGHGAYGIVCSARFAEAA---EDTTVAIKKVTNVF-----SKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGS-----INGLYLYEE
.. ...|| |.||.|  ||  .      .  ||.||.          |. .   ..|| .||..   |.|| .|.|  .   .| .     .| ||.  |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

LMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-----LKICDFGLARGYSEN---PVENSQFLTEYVATRWYRAP
 |. |  ....          .....|.| || |.||  ..|||||| |.|.| . .     ||| |||||| .. .   . |... .|  | |.|||||
YMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYRAP

EIMLSYQGYT--KAIDVWSAGCILAEFLG---GKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLE
|. |  . |.   .||.||.|||.||..    .||.| |.   .||  | ...||| ...   .  .  .||                        |||.
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGV--TKLPDY------------------------DLLN

QMLAFDPQKRITVDEALEHPYL
.||..||.|||. ..||.|||.
KMLCYDPKKRISAEQALQHPYF

Kinase SLT2.AA Pkinase 23-318 26 6.7e-84 289.83 Pfam 1-293 (293) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-293/293
Sequence Identity: 26% (86 aa)

FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLR--ELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLY--EELMEC-----
..... || |..| |. ..     .  .||.|..  .  |   ... .|  |....... .|.||  |||.           . ..|   |..|.     
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--------KDHIYMVMEYCEGGLYVM

DMHQIIK--SGQPL--TDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQL----KICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIML
| . .|.  .. ..  .. . ... ||||.||.|.||  ..|||||| |.|.. ....    ||||||||. ..     |.. .| .. |.||.|||. .
DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR

SYQGYTKAIDVWSAGCILAEFLGGKPIFKGK----DYVNQLNQILQVLGTPPDET-----------LRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQ
..|.|....|.||.||||.|.| |.|.|.|.    . ..|.  | ...|.|...            .|.   .                .  . .|... 
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H--------------F-HWTF-HNWSEE

ALDLLEQMLAFDPQKRITVDEALEHPYL
..|... .|..||.||.| ...|.||..
CKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase SLT2.AA MAPK-Unclassified 23-176 45 1.5e-58 200.86 In-house 1-157 (575) Show / Hide
Range on Protein: 23-176
Range on HMM: 1-157/575
Sequence Identity: 45% (74 aa)

FQLIKEIGHGAYGIVCSARFAEAAE-DTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSIN----GLYLYEELMEC---D
  ..| || ||||.||  |. .       ||||||. .|    .|||.|||. .||.   | ||  . |.   ||...  |     .|.  ..|.    |
YEYQKNIGSGAYGQVC--RAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLN-HPNIIQIQDI---FYNKELHNQEFDDIYIVMDYMQTSLFD

MHQIIKSGQ-PLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLAR
.|||||| | .. . | | |.|||| ||||.||| ..|||||| |||.| || ..|||||..|
LHQIIKSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR

Kinase SLT2.AA MAPK-Unclassified 189-318 33 2.2e-58 200.25 In-house 405-575 (575) Show / Hide
Range on Protein: 189-318
Range on HMM: 405-575/575
Sequence Identity: 33% (57 aa)

LTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGG-----------KPIFKGKD--------------------YVNQLNQILQVLGTPPDETL
.|.||.|||||||||||| . |....| ||.|||.|| .             .|.|.|.|                    .. |.. |. .||.|| | .
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC

RRIGSKNVQDYIHQLGFIPKVPFVNLYPNANS----------QALDLLEQMLAFDPQKRITVDEALEHPYL
..|.. .. .||  ..  . |.|  |.. ...          ...|.. .||.|.|.|||| |.|||||| 
NFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF

Kinase SLT2.AA TyrKc 23-318 22 1.2e-13 -2.24 SMART 1-280 (280) Show / Hide
Range on Protein: 23-318
Range on HMM: 1-280/280
Sequence Identity: 22% (73 aa)

FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHF-RGHKNITCLYDMDIVFYPDG----SINGLYLYEELMEC-DMH
 .|.|..|.||.|.|. ..       ..||.|.. .        .  .||.......   |.|| .||    |   .|    .|  |..  |.|.  | .
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLY---GVCTQQGRNFMYIEPLMIVMEYMPHGDLK

QIIKSGQP-LTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSEN-------PVENSQF--LTEY-VATRWYRAPEIML
. ... .| |. ..  || .|| ||  |.||  . ||||   | ||... . ||.||||.|   .         .  ..    . . .  ||. ||| . 
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-

SYQGYTKAIDVWSAGCILAEFL-GGKPIFKG----KDYVNQLNQILQVLGTPPDETL----RRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLE
 |  .| . |||| |  . | .  |..   |    .    .. . ..  . .|                              |    . . .   .. .
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------F----VCCPDEMYQIMK

QMLAFDPQKRITVDEALEHPYL
|  ..|| .| |  |   | ..
QCWHEDPEDRPTFSEI--HECF

Kinase SLT2.AA Pkinase_Tyr 23-89 25 3e-06 22.01 Pfam 1-70 (270) Show / Hide
Range on Protein: 23-89
Range on HMM: 1-70/270
Sequence Identity: 25% (18 aa)

FQLIKEIGHGAYGIVCSARFA--EAAEDTTVAIKKVTNVFSKTLLCKRS-LRELKLLRHFRGHKNITCLY
 ...|..|.||.| |. ..    .  ....||.|.. .  ..  .|... .||.|.....  |.|| .||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY

Kinase SLT2.AA Pkinase_Tyr 132-176 46 4e-06 21.52 Pfam 115-159 (270) Show / Hide
Range on Protein: 132-176
Range on HMM: 115-159/270
Sequence Identity: 46% (21 aa)

SFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLAR
.. .|| .|. | .|    ||||   | ||. . . |||||||||
QMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR