Gene YGR052W (Bakers Yeast)
YGR052W
Group:
Other
Family:
Other-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| YGR052W.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 285 | Kinase domain by global Sugen HMM | Fasta, JSON |
| YGR052W.AA | Protein | Refseq_NP | 369 | Hypothetical ORF; Ygr052wp [Saccharomyces cerevisiae] | Fasta, JSON |
Protein domains of YGR052W.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Pkinase | YGR052W.AA | Pkinase | 2-223 | 28 | 5.7e-51 | 180.46 | Pfam | 1-213 (293) | Show / Hide |
Range on Protein: 2-223
Range on HMM: 1-213/293
Sequence Identity: 28% (68 aa)
YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKN-----EYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECG----DLYDFLD
|...| | ||.|..|||. .. ||.|| .| .... .. | .|| |. ||||. ..|...|.... ||.||||.| ||.|..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS
IAKSQGSPSSPSL--IQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDI----KLADWGHA----IQSPKSNDFQIGTDNYRAPETFSGRVS
.. .. . .....|..... . || || |||.||||||. ||.| |..|.| | . . .. || .|.|||
T------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----
NSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFR
| .. .| ||.| .......| .|.
------------GGQYYGPKVDMWSCGCILYEMLCGRPPFP
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| Kinase | YGR052W.AA | CAMK | 7-218 | 20 | 9.6e-50 | 158.07 | In-house | 1-330 (425) | Show / Hide |
Range on Protein: 7-218
Range on HMM: 1-330/425
Sequence Identity: 20% (70 aa)
SIQSGTFSTVYKAWSTTHN------------RYVALKITPKYKTS-----------------------------EANMKNEYDVMKILSSCNP---HPNI
. .|.|..|... . . . || || .| | . ..|...|...|| |.. . ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
CSMLDFYTD-------------------DSYYIMVL---EYCECGDLYDF-LDIAKSQGSPS----------SPSLIQIDMQKIIKQLCSAISFAHSLGI
......| | |....||. |||. |.|.| .| ...|... . . . .....|.|||. . ||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
AHRDIKPENILLTIN-----------------GDIKLADWGHAIQSPKSND-F-------------------------QIGTDNYRA-PETFSG-RVSNS
.|||.|||||||. | ..||..|.| |.. ..... | . || | | || ..| . .|.
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
CFKKNFDRSSA----PLYNTYQADYWSLGATIFYLMFG
. | | ....| ||.| . . |
Q-------N-ATDEEKPYYGPKCDMWSCGVILYIMLCG
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| Kinase | YGR052W.AA | Ciliate-E2 | 2-246 | 20 | 4.4e-45 | 152.69 | In-house | 1-307 (365) | Show / Hide |
Range on Protein: 2-246 Range on HMM: 1-307/365 Sequence Identity: 20% (70 aa) YTKLRSIQSGTFSTVYKA--WST---------------------THNRYVALKITPKY-KTSEANMKNEY----------DVMKILSSCNPHPNICSMLD | ... | .|.|..|||. |.. . . ..|.|| |. . . ...... ..||.. | ||||. | . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLN-HPNIIKMYE FYT--DDSYYIMVLEYCECGDLYDFLDIAKSQG-----SPSSPSLIQIDMQKIIKQLCS---------------AISFAHSLG-IAHRDIKPENILLTIN .. ||... .|.|||. |||.|.. . | . . .. ...|.||... |. . || . | ||||||||||. CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--- GDIKLADWGHAIQSPKSND-------------------------F---------QIGTDNYRAPETFSG-----RVSNSCFKKNFDRSSAPLYNTYQADY ||..|.| . . ..|. . ..|| .| ||| ..| .. . .|..|. --IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ-------------QKQKGYDYKCDI WSLGATIFYLMFGDCLFRVSKSKKVQHLKNFDEFEKDPFAF |||| ......|| | ... .. .. | WSLGVILYEMLFGKPPF-------------QQQIKQCKIDF |
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| Kinase | YGR052W.AA | S_TKc | 2-270 | 25 | 9.9e-44 | 152.52 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 2-270 Range on HMM: 1-231/231 Sequence Identity: 25% (72 aa) YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCEC--GDLYDFLDIAKSQGS |..|| | .|.|..|||.. . .|.||.|| . ....| ...| ||||. ..|.. | ... ||.|||. |||.|... ...| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL PSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYN .. . . .....|.|.|. . ||.|| |||.|||||||. ||..| | | | . ..|| .|.||| . |. RF--PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL-------------------GYG TYQADYWSLGATIFYLMFGDCLFRVSKSKKVQHLKNFDEFEKDPFAFIYRKYVVP---RLSCGYNDE----EDLHVSL . .| ||.| ... .. | .|. . .... .. || . .. |... . .| . KCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | YGR052W.AA | CAMKL | 2-151 | 28 | 1.1e-42 | 133.96 | In-house | 1-172 (297) | Show / Hide |
Range on Protein: 2-151 Range on HMM: 1-172/297 Sequence Identity: 28% (51 aa) YTKLRSIQSGTFSTVYKAWSTTH-NRYVALKITPKYKTS-EANMKN---------------EYDVMKILSSCNP-HPNICSMLDFYTDDSY------YIM |. .. . |.|..| |. . . .. || || | |.. . .||. |. || |. .. ||||..... ...... . . YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN--IGKHPNIIKLYEVIETPEHDIETKKIYL VLEYCECGD--LYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGD--IKLAD |.|||. |. |.|... . . .. . ... .|..||... ||.||.|||||||||||. ||. ||..| VMEYCSGGEMDLFDYIVKHGHRR----GRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIID |
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| Kinase | YGR052W.AA | Other-Unique | 5-276 | 15 | 3.7e-41 | 137.29 | In-house | 1-249 (249) | Show / Hide |
Range on Protein: 5-276 Range on HMM: 1-249/249 Sequence Identity: 15% (41 aa) LRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPS ...|..||...|||.... ...|.| |.. ... ....|.|. .. ... . .|. . ...| .... ....|..|.... .. .... ... IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNN---KRE-QIYHYQ-IIH-CIFYWT-MNHCHLCFCYEHCPNMIFYIMYPWY--HHHCEC LIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQAD .|... ..... .......| .. |.||.|.||....| .......||.| . | ..... . .. . | .. .. .. | . . ... | QCQCEHWMNCCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNI-P----TI-I-IEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFD YWSLGATIFYLMFGDCLFRVSKSKKVQHLKNFDEFEKDPFAFIYRKYVVPRLSCGYNDEEDLHVSLQHTRQY ||.|| |. . ||...|... ... .| ... . .......... . ..... .... .. . .....| YWPLGEKIDQYHFGCYHFHMNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY |
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| Kinase | YGR052W.AA | CMGC | 2-175 | 18 | 1e-40 | 130.88 | In-house | 1-295 (513) | Show / Hide |
Range on Protein: 2-175 Range on HMM: 1-295/513 Sequence Identity: 18% (55 aa) YTKLRSIQSGTFSTVYKAWS--------------TTHNRYVALKITPKYKTSEANMK-------------NEYDVMKILS-------------SCNPHPN |.... | .||...|||.. . |..||.|. . . | .| | .| |. ... |.| YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN ICSMLDFYTDDS-----------------YYIMVLEYCECGDLYDFLDIAK--SQG-SPSSPSLIQ----------IDMQKII------KQLCSAIS--F | ...|..... . .| ||... |||.... . || | | . . .... .|.. .. . IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY AHSLG--IAHRDIKPENILLTIN--------------------GDIKLADWGHAI--QSP----------------------KSNDFQIGTDNYRAPE || . | |||.||||||.. | | .|..|.| | .. . . .. | ||||| CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPE |
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| Kinase | YGR052W.AA | Ciliate-E2-Unclassified | 2-222 | 21 | 5.3e-39 | 132.93 | In-house | 1-270 (352) | Show / Hide |
Range on Protein: 2-222 Range on HMM: 1-270/352 Sequence Identity: 21% (65 aa) YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITP--------KYKTSEANMKNEYDVMKILS---------------SCNPHPNICSMLDFYTDDSYYIMV |.... | .| |..|||. .. | |.|. ...... ...|| . |.... . .|||.| |.. .|. . ..| YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV LEYCECGDLYDFLDIAKS---------------------------QGSPSSPSLIQIDMQKIIKQLCSAISFAHSLG-IAHRDIKPENILLTING---DI .|||| ||| ... . |. . .....|....... |. . | ||||||||||.. || | MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKA-------------KFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYI KLADWGHAIQS------------------PKSNDFQIGTDNYR----APETFSG-RVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF |..|.| .... .. . ..|| || ||| . | ..| . |..|.|||| .....|| . | KIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--------------YKCDIWSLGVILYEMLFGYYPF |
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| Kinase | YGR052W.AA | Ciliate-E2a | 2-153 | 31 | 1.1e-35 | 102.57 | In-house | 1-154 (275) | Show / Hide |
Range on Protein: 2-153 Range on HMM: 1-154/275 Sequence Identity: 31% (51 aa) YTKLRSIQSGTFSTVYKAWST-THNRYVALKITPKYKTSE---ANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQ | ... | .|.| ||.| | .... |. |. .. ....|| . |. | ||||. . ..| |...| .|.|||| |.||| . |.. YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQL----DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRF GSPSSPSLIQIDMQKIIKQLCS-AISFAHSLGIAHRDIKPENILLT---ING----DIKLADWG . .. .|..|| . ... |...| |||.||||||.. |. |||..|.| FEE------IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFG |
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| Kinase | YGR052W.AA | CAMK-Unique | 2-153 | 20 | 4.1e-29 | 93.1 | In-house | 1-218 (363) | Show / Hide |
Range on Protein: 2-153
Range on HMM: 1-218/363
Sequence Identity: 20% (47 aa)
YTKLRSIQSGTFSTVYKAWS-TTHNRYVALKITPKYKTSEANMK--------------------NEYDVMKILSSCNPHPNICSMLDF----YTDDS---
|...|.| .|.|. ||.. .| .. .. .. .... .| ...| .. |||| .|. . |.
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVD----HPNIIKLYDWNNPIFCDRKYPL
------------YYIMVLEYCECGDLYDFLDIA-----------------KSQGSPSSPSLIQ--IDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLT
|. .|.|||..|||.| .. ..|| .. | . |. .| ||....||..| |||.|.|||..
CDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQG-----HFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVC
INGD----------------IKLADWG
... |||.|.|
YSFKDNNHHRDFPYDWSNWHIKLCDFG
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| Kinase | YGR052W.AA | TKL | 8-194 | 15 | 2.4e-28 | 99.17 | In-house | 1-270 (364) | Show / Hide |
Range on Protein: 8-194
Range on HMM: 1-270/364
Sequence Identity: 15% (45 aa)
IQSGTFSTVYKAWSTTHN--------RYVALKITPKYK-------------------------TSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSY
| ||.|..|||. .. . || |. .. ... ... | .....|... ||||.... . .. ..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLR-HPNIVQFMGYCCCPPC
-------------YIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLG--------IAHRDIKPENILLTINGD-------
. .| |||..|.|...| . ..... ...... || . |.|||.|..|||. |.
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMY
-------IKLADWGHAIQSPKS----------------------NDFQIGTDNYRAPETFSGRVSNSCF--------KKNFDRSS
.|..| | . .| . |.|| .. ||| . | ... .. .. ..
NPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKC
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| Kinase | YGR052W.AA | MARK | 115-180 | 44 | 5.8e-19 | 58.77 | In-house | 111-180 (262) | Show / Hide |
Range on Protein: 115-180 Range on HMM: 111-180/262 Sequence Identity: 44% (31 aa) KQLCSAISFAHSLGIAHRDIKPENILLTING--DIKLADWGHAIQSPKSNDFQI--GTDNYRAPETFSGR .|..||... || .|.||||||||||. || .||..| | .|. | . . || | ||| |... RQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKK |
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| Kinase | YGR052W.AA | Pkinase_Tyr | 2-134 | 23 | 1.4e-12 | 43.2 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 2-134 Range on HMM: 1-137/270 Sequence Identity: 23% (34 aa) YTKLRSIQSGTFSTVYKAWST----THNRYVALKITPKYKTSE----ANMKNEYDVMKIL-SSCNPHPNICSMLDFYT-DDSY--YIMVLEYCECGDLYD |... . .| | .|||. . .. || |. . . ..| . . .| .|| | . |||| ... | .. ...|.||...|||.| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH----HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD FLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDI .| . .. ..| |. .. | ... .. .| .. |||. YLRKHR----EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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| Kinase | YGR052W.AA | MARK | 2-91 | 28 | 2.8e-11 | 33.28 | In-house | 1-93 (262) | Show / Hide |
Range on Protein: 2-91 Range on HMM: 1-93/262 Sequence Identity: 28% (28 aa) YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSE----ANMKNEYDVMKILSSCNPHPNICSMLDFYT--DDSY-YIMVLEYCECGDLYDFL | |. | |....|..| .. .| ||.|| .|.| .. | . | ..|| |. |||| .... . . ...||.. |.|||.. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLD----HPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYI |
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| Kinase | YGR052W.AA | TyrKc | 2-233 | 16 | 1.2e-09 | -66.88 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 2-233 Range on HMM: 1-280/280 Sequence Identity: 16% (48 aa) YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKIL--SSCNPHPNICSMLDFYTDD-------SYYIMVLEYCECGDLYDFLD |... . .| | .|||. . . || | ... .. . .| .|. | . |||| .. |.. . .|.||.. ||| |.| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGH----HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR IAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKS-------NDFQI----GTD-----NYRAPET . . | |. .. | .. .. || .. |||. |.|.. |. .| .| | . |.. |||. KHRPK-------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC FSGRVSNS-----------------CFKKNFD-----RSSAPLYNTYQAD-YWSLGAT------------IFYLM----FGDCLFRVSKSKKVQHL . .. .. . . . | . ... .. . . .. .| | | . | .. . INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | YGR052W.AA | CAMK-Unique | 201-218 | 36 | 0.055198 | 2.11 | In-house | 268-289 (363) | Show / Hide |
Range on Protein: 201-218 Range on HMM: 268-289/363 Sequence Identity: 36% (8 aa) YQA----DYWSLGATIFYLMFG .| | ||||.. .|. .| QQCSPASDIWSLGVIMYYMLCG |
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