Gene CRK7 (Human)

CRK7

Species: Human
Alias: CRKR, CrkRS, CRK7, CRKRS, KIAA0904
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 17q12-q21.1,

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7

Sequence

Name Sequence Type Origin Length Description Download
CRK7.kin_dom Protein Kinase Domain Sugen Kinome 294 None Fasta, JSON
CRK7.AA Protein Sugen Kinome 1490 None Fasta, JSON
CRK7.NA RNA Sugen Kinome 8310 None Fasta, JSON

Protein domain

Protein domains of CRK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CRK7.AA CRK7 727-1020 65 5.5e-243 813.52 In-house 1-343 (343) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-343/343
Sequence Identity: 65% (224 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNE---KEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGL
...|..|||||||||||||.|.|||.|||||||.|||   |||||||||||||||||| |...||.||||||||||..|||.||.||.||||||||||||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LESG-LVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE-SRPYTNKVITLWYRPPELLLGEERY--------
|||. ..|||....|.|||||.||..||||||||||||||||||.||.|..|.||||||||||||| .|||||.||||||||||||||||||        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------TPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLR
                              .|.||.||||||||||||||||||.| |.||||.|...||||.|..||.|.|||..||||||.||.||||
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

EEFS------FIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
|||.      |.|...|||||.||.|||.||.|||..||.|..
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CRK7.AA CDK 727-1020 42 2.4e-170 549.34 In-house 1-284 (284) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-284/284
Sequence Identity: 42% (138 aa)

FDIIGIIGEGTYGQVYKAKDKDTG-----ELVALKKVRLDN-----EKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDK--GAFYLVFE
....  |||||||.||||.||.||     ..|||||.|..|     |||||||||||||..|..| |  .|. ......|... .. |||    .|.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQ-----IKLADFGLARLYNSE-----ESRPYTNKVITLWYRPP
||||||.....          ||..|.||..||.|||.....|||.|..|||.|| |.     .|.|||||||.....     ..|.||..|.|||||.|
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ELLLGEERYT--PAIDVWSCGCILGELFT---KKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDH
|||||...|.  ..||.||.|||..|.||   .||.|. . |. ||..|.|.||.|.. .||.| |||..                         |||..
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNK

MLTLDPSKRCTAEQTLQSDFL
||..||.||..||| ||....
MLCYDPKKRISAEQALQHPYF
Kinase CRK7.AA CMGC 727-1020 26 6.5e-140 462.92 In-house 1-513 (513) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-513/513
Sequence Identity: 26% (137 aa)

FDIIGIIGEGTYGQVYKAKD--------------KDTGELVALKKVRLDN---------EKEGFPITAIREIKILRQL----------------IHRS-V
..||. |||||||.|||..|              ..|.|.||.||....          ||.||||.|.||||||..|                 |.  .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNMKEIVTDKQDALDFKKDK-------GAFYLVFEYMDHDLMGLLES--------GLVHFSEDH------------IKSFM------KQLMEGLE--YCH
|....|...|... . ..||         .||||||||||| .....        . ...|| |            ||.||      .|. .||.  |||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

KKN--FLHRDIKCSNILLNNS--------------------GQIKLADFGLARLYNSE--------------------ESRPYTNKVITLWYRPPELLLG
...  ..|||.| .|||.|.                     |..|..|||||| |...                    ..||||. | |.|||.||.|||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

EERYT---------PAIDVWSCGCILGELFTK--------KPIFQ-----------ANLELAQLELISRLCGSPC---------------PAVWPDVIKL
 ..||         ..||.||.|||..|..|.        ||.|.            . .. ||..| ...|.|.               .  ||..|||
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PYFNT-------------MK------------PKKQYRRRLREEFSF-----------------------------------IPSAALDLLDHMLTLDPS
|..|.             ..             ...... ... | .                                   ... |.|||. ||..||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRCTAEQTLQSDFL
|| |||| || ...
KRITAEQALQHPYF
Kinase CRK7.AA CDK9 727-1020 42 1.2e-117 397.14 In-house 1-340 (340) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-340/340
Sequence Identity: 42% (145 aa)

FDIIGIIGEGTYG-----------QVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEY
.. .  || ||.|            |.||. | .. .||.||| ..|||||||||| ||||.| .| |  |||. ||   |  |    ||.  |||||..
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEICRTKATAYNRYKDRATFYLVFDF

MDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLY----NSEESRP-YTNKVITLWYRPPELLLGE
 .||| |||   .| ||  |||. |..|| || | |.   |||| |  |.|    |  ||||||||| .    |.   || ||| |.||||||||||||.
CEHDLAGLLSNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLGD

ERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTM-------KPKKQYRR---RLREEFS-------------
  | |.||.|  |||. |. |  || | | |  || ||| ||||  |.||| . ... .|.|        || |.|.   |..                 
RNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNYMKFDAPDSKTDPFGK

-------FIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
            |..|.| .|..|| || .... |  |. 
NVKQHDSATDQQACHLIDKLLNIDPKKRMDSDEALDHDWF
Kinase CRK7.AA CDC2 727-1020 38 8.70000000001e-117 360.58 In-house 1-301 (301) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-301/301
Sequence Identity: 38% (122 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEG--FPITAIREIKILRQLI-HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGL
.  |  ||||||| |||.||..|...|||||.||..| ||  .| |||||| .|  |  |  .|  ....                |.||||.|.||  .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-----------NKLYMVFEYLDMDLKKY

LESGLV---HFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYT--NKVITLWYRPPELLLGEERYTPAID
..  ..   |.... .||.|.|. .|...|| .  .|||.| .|||....|.||.|||||||  .   .|.||    |.|||||.||.|||..||. ..|
MDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFG-IPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVD

VWSCGCILGEL---FTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPK---KQYRRRLRE-----EFSFIPSAALDLLDHMLTLDPSK
.|| |||. |.    ||||.|..  |  ||  | |  |.|    ||.| .||....  |.   .. .. .       ..|...  ..|||. || .||.|
MWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQK

RCTAEQTLQSDFL
| .|.. ||  ..
RISAKEALQHPYF
Kinase CRK7.AA PITSLRE 727-1020 42 4.6e-116 391.88 In-house 1-295 (295) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-295/295
Sequence Identity: 42% (128 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLD--NEKEGFPITAIREIK-ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGL
| ..  |.||||| ||.|||| |.| ||||.. ..   ||||||||..|||. ||. | |. .|| ||||          ...   |.|.||..||| .|
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIV--------MGSNMDKIYMVMEYVEHDLKSL

LESGL---VHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW
.|        |..  ||..| ||  | |. |..  .||| |.||.|....|. |..|||||| | |   .|||  |.||||| |||||| . |....|.|
MENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSP-IKPYTPCVVTLWYRAPELLLGCKKYSTPVDMW

SCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMK-PKKQYRRRLREEFS---FIPSAALDLLDHMLTLDPSKRCTAEQTLQ
| |||..|. |.||.|| . |. |.. |  . | |    ||.. .|| .. |.  ...    ||. |     |   ..|||  |||..| .| ||.. |.
SVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALK

SDFL
 .. 
HPWF
Kinase CRK7.AA CDK7 727-1020 38 1.8e-112 300.92 In-house 1-288 (288) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-288/288
Sequence Identity: 38% (115 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVR----LDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMG
...|  ||||... |||| |. ||. || ||..     .  | |   |||||||||. . |  |...  |   |             .|||..|| ||  
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKS----------NIQLVFDFMDWDLEV

LLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSC
  .   . .   |||..|...  ||||||.   ||||.|  | |.|  ||.|.||||||| | |   | || .|.| ||| |||| |   |....|.|| 
VIKDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPN-RIYTHQVVTRWYRAPELLFGARHYGTGVDMWSV

GCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQY-RRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
|||. ||    |..    .. ||. | .  | | .. ||.. ... ....|.   | |  ||. |.  .  .|||.  |.|..|.||.|. | |.... 
GCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CRK7.AA CDK5 727-1020 40 4.5e-102 323.37 In-house 1-287 (287) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-287/287
Sequence Identity: 40% (120 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIV-TDKQDALDFKKDKGAFYLVFEYMDHDLMGLLE
.. .  ||||||| ||||..|.|.|.||||.||||.| || | |||||| .|. | |. .| .  .. ..|              ||||..| ||   ..
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKK-----------LTLVFEFCDQDLKKYMD

SGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI
|  .  . . ||||| ||. ||..||... |||| |  | | |  |. ||||||||| .     | |.  |.|||||||  |.|   |.  ||.||||||
SCNGEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAF-GIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCI

LGELF-TKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFN---TMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
. |.  . .| |  | .  || .| .. |.||   || . ||| ..   .  |. . .  . .      .  .|||  || ..| .| .|.. |.  . 
FAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CRK7.AA Pkinase 727-1020 32 4.6e-98 336.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-293/293
Sequence Identity: 32% (101 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIR--EIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDH-----D
. |...||.|..|.|||...|.||..||.|......||.....|..|  ||.|.. | |  .| ......|          |.  |.|.||...     |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----------KDHIYMVMEYCEGGLYVMD

LMGLLE-SGLVHF--SEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQI----KLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEER
|. ... .    |  ||...|..|.|. .||||||.....|||.| .|||..| |.|    |..|||||....   .. .|  . |.||..||...| . 
LFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQY

YTPAIDVWSCGCILGELFTKKPIFQAN----LELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKR
|.|..|.||||||| |.....|.|.        . |...| |  | | .  ||  .  .||.  .. .   . ...    ......|... .|..||.||
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKR

CTAEQTLQSDFL
.|||| ||....
PTAEQILQHPWF
Kinase CRK7.AA S_TKc 727-1020 28 1.1e-97 331.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-231/231
Sequence Identity: 28% (88 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDH---DLMGL
..|. .||.|..|.|||...|.||..||.|...         ....|||.||..  |  .|.....  |           . .|.|.||.|.   ||. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-----------DHLYMVMEYCDGDLGDLFDY

LESGLVH-----FSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTP-AI
...   |     |.| |....|.|. ..|||||.....|||.| .||||..  .||..||||||..        |  . |.||..||.|     |.. ..
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKC

DVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQ-
|.||||||| |... .| |.      |.... ...|                                    .. |.|.....|. ||.|| || . || 
DWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

------SDFL
        ..
EWDIKCHPWF
Kinase CRK7.AA CDK10 727-1020 42 9.5e-95 321.08 In-house 1-285 (285) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-285/285
Sequence Identity: 42% (124 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLES
|. .  .|||||| ||.|.|  . |.|||||||.| ||.| || ..|||..| |. |  .|...|.|  ..  ||      . .|| .| . ||  ||. 
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQH--LD------SIFLVMQYCEQDLASLLDN

GLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCIL
    |.| ..|  | |.. || | |..  .|||.| ||.|.   | ||.||||||| | .   .| | |..||||| ||||||    | |||.|  ||||
MPQPFTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMY-GVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCIL

GELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
|||  .||..  | |..|...|  | |.|  ..||   .||  .    |||    |.. | ..  . . ||. ..  .| || |||..|.| . 
GELLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase CRK7.AA MAPK 727-1020 32 1.4e-82 280.69 In-house 1-328 (328) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-328/328
Sequence Identity: 32% (106 aa)

FDIIGIIGEGTYGQVYKAKDKD------TGELVALKKVRLDNEKEGFPITAIREIKILRQL-IHRSVVNMKEIVTDKQDALDFKKDK---GAFYLVFEYM
..|.  ||.| ||.| .|.||       .|. ||.||.    ... .   ..||||.|| .  |  ......| | ..   |  ...     .|.|.|.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEM-Q-DDQNSLEEFNDIYIVMELM

DHDLMGLLESGLVHFSEDHIKSFMKQLMEG--LEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPY-------------TNKVITLWY
..||  ...|.  . |.|||..|| |.  |  | | |  | .|||.| ||||.|  .. |..||||||   .|.. ..             |  | | ||
ETDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWY

RPPELLLG--EERYTPAIDVWSCGCILGELFT-KKPIFQANLELAQLELISRLCGSPCPAVWPDVI--KLP--YFNTMK-PKKQYRRRLREEFS----FI
| ||..|.    .|| |.|.||.|||..|. |  ||.|. .  . |..||  ..|.| . ..  .   . .  |.  .. ..|. .. ... |.      
RAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNA

PSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
 . |.|||. ||..||.|| |.|. ||  ..
NPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CRK7.AA Pkinase_Tyr 727-931 28 8e-21 71.14 Pfam 1-209 (270) Show / Hide 
Range on Protein: 727-931
Range on HMM: 1-209/270
Sequence Identity: 28% (63 aa)

FDIIGIIGEGTYGQVYKAKDK----DTGELVALKKVRLDNEKEGFPITA------IREIKILRQL-IHRSVVNMKEIVTDKQDALDFKKDKGA--FYLVF
  ..  .||| .|.|||.. |    .|.  || |...     ||    .      .||.||..||  |  .|..  ..|         ....    |.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT---------DQGEPNQIYIVM

EYMDH-DLMGLLESG---LVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLY-NSEES-RPYTNKVITLWYRPPELL
||| | ||   | .      ...  .. ..  |  .|.|| . ||. |||. . |.|.......| .||||||.  | ..  |  ..  .     .|| .
EYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECI

LGEERYTPAIDVWSCGCILGELFT
   . .| . |||| |  . |.||
NYGK-FTTKSDVWSFGVLMWEIFT
Kinase CRK7.AA TyrKc 727-1020 21 4.7e-15 20.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 727-1020
Range on HMM: 1-280/280
Sequence Identity: 21% (70 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQL--IHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDH-DLMGL
   . ..||| .|.|||.. |   . || |... |          .||..|...|   |  .|..  ..|...    |    .  ..|.|||.| ||   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--F-MYIEPLMIVMEYMPHGDLKDY

LESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSE----ESRPYT------NKV--ITLWYRPPELLLGEE
| .   ... ..  ||. |  .| || |.||. |||. . |.|... ...| .||||.|   ..    ||  |       ..   . .   .|| .  . 
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

RYTPAIDVWSCGCILGELFTKKPIFQAN-----LELAQLELISRLC-GSPCPAV----WPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHML
..|.. |||| |  . |.||       .     .. ...    .     |.|.                               |   |..  ..     
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------FVCCPDEMYQIMKQCW

TLDPSKRCTAEQTLQSDFL
  ||..|.| ..    ...
HEDPEDRPTFSEI--HECF