Gene MOK (Human)

MOK

Species: Human
Alias: MOK, RAGE1, RAGE
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards ,
Annotation: Consensus chromosomal location: 14q32.31,

Classification

Group: CMGC
Family: RCK
Subfamily: MOK

Sequence

Name Sequence Type Origin Length Description Download
MOK.NA RNA Sugen Kinome 1935 None Fasta, JSON
MOK.AA Protein Sugen Kinome 419 None Fasta, JSON
MOK.kin_dom Protein Kinase Domain Sugen Kinome 282 None Fasta, JSON

Protein domain

Protein domains of MOK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MOK.AA MOK 4-285 87 6.4e-254 805.19 In-house 1-283 (283) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-283/283
Sequence Identity: 87% (247 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEK
||||||||||||||||||||||||||||||||||.|||||||||||||||.||||||||||||||||||||.|.||||||||||||||||||||..|..|
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQK

KIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFP
|||||||||||||||.||||||||||||||||||||.|||.|||||||||||||||||||||||||||||||||.|||.||.||.||||||||||.||||
KIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQDHLKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPLFP

GVNELDQISKIHDVIGTPAQKILTKFK-QSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF
||||.|||||||||.|||.||||.||| ||||||.||||||||||..||.||..|||...|.|..|||||||.|||..|||||
GVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase MOK.AA RCK 4-285 47 2.6e-203 651.34 In-house 1-298 (298) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-298/298
Sequence Identity: 47% (141 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDMNIYELIRG---RRYPL
|..| ..|.||...|||.|....|...|.|.|||.|.|.|...|||||..||.|||||||..|.||..|.....|....|.||||.|.....   || .|
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYL

SEKK--IMHYMYQLCKSLDHIHRNGIFHRDVKPENILIK----------QDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSA
.|..  |...|||....|.|.|..|.||||.|||||...          ||..|..|||.||...||.|||.|.||||||||||||....|...||.|. 
PENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAV

GCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFK-QSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF
||..||. .|.||||| .|.||| ||..|.||| .|...... ....|||.||..||.... |..|.|..|..|.. |...||..||.|.||||||||
GCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase MOK.AA CMGC 4-285 23 6.4e-113 372.59 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-513/513
Sequence Identity: 23% (121 aa)

YKAIGKIGEGTFSEVMKMQS--------------LRDGNYYACKQMKQRFESIEQV----------NNLREIQALRRLN----------------PHPNI
|. |.||||||...| | .                ......| | .|..|. ...             ||||. |..||                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

LMLHEVVFDRKSG---------------SLALICELMDMNIYELIRGRRY--------PLSEKK------------IMHYM------YQLCKSLD--HIH
. |.... ...|                .| |. |.||.. |..|.  .         |||| .            | ..|      ||....|.  ..|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

RNG--IFHRDVKPENILIKQD---------------------VLKLGDFGSCRSVYSK----------------------QPYTEYISTRWYRAPECLLT
...  |.||| ||||||| ..                     .||..|||..|.. .                       .|||.|..|||||||| || 
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

DGFYT---------YKMDLWSAGCVFYEIAS--------LQPLFPGVNE-----------LDQISKIHDVIGTPA---------------QK--------
.. ||         ...| ||.||.|.|.          ..||||| .|           .||. || .|.|||                ..        
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

------------------ILTKFKQSRAMNFDFPFKKGSGIPLLTTN-----------------------------------LSPQCLSLLHAMVAYDPD
                  .  . .. . .|..|| ...  .  |  .                                   ..||.. ||  |  ||||
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

ERIAAHQALQHPYF
.|| | ||||||||
KRITAEQALQHPYF
Kinase MOK.AA MAK 4-285 32 5.3e-94 299.62 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-352/352
Sequence Identity: 32% (114 aa)

YKAIGKIGEGTFSEVMKMQS------------------------------LRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNILMLHEVVFDR
|  | ..| ||. .||. ..                                 |   | |.||. | | |   ||||. .|. || ||||  | ||. | 
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

KSGSLALICELMDMNIYELIRGRRY-PLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQ------------------DVLKLGDFGSCRSVYS
    | .. | |  | |... .|.   ..|  |   |||    | ..|..| |||| |||||..                    ...|. |||  | . |
ENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLAREIRS

KQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKI-----------------LTKFKQSRAMNF
| ||| |.||||||||| ||  . |   .|.|  ||.  |. .. ||||| .| ||| ||  |.|||  .                     .. . .|||
KPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQLAHMMNF

DFPFKKG---SGIPLLTTNLSP-QCLSLLHAMVAYDPDERIAAHQALQHPYF
 ||   .   . .  |  | |.   . |.  | ..||..|  | |....|||
RFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase MOK.AA S_TKc 4-285 29 2.1e-86 294.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-231/231
Sequence Identity: 29% (88 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDM---NIYELIRGRRYP-
|. . |||.|.|..|.| .  ..| ..|.|..|         . .|||| |..   ||||  |..|  |   ..| .. |..|    . ...|. |... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTY-KMDLWSAGCVFYE
    ..|  . .||||.|. |...|..|| |||.||||||. . ..|..|||..| .      | .. |.||.||| |     |.. | | || ||..||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

IASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQ-------HPYF
 .. .|.||      |. .. ..||                                   ||......  .  .||..|. | .|||       ||.|
MLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MOK.AA CDK 4-285 31 4e-83 265.77 In-house 1-284 (284) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-284/284
Sequence Identity: 31% (101 aa)

YKAIGKIGEGTFSEVMKMQSLRDG-----NYYACKQMK------QRFESIEQVNNLREIQALRRLNPHPNILMLHEVVFDRKSG---------SLALICE
|. . ||||||. .| | .....|     ...| |. .      .. .       .|||  |. |  ||||  ||.|. . ..          .| .. |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

LMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIK-QDV-----LKLGDFGSCRSVYS-------KQPYTEYISTRWYRAP
 ||.  .....          | .||.|| . |...|.|.| ||| || ||||  . .     ||..|||  |   .        ..||  . |.|||||
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ECLLTDGFYT--YKMDLWSAGCVFYEIAS---LQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAM
| || .  |.     |.||.||.|.|..     .||||| .|.||. || ...|||  ..   ...                             ||  |
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DLLNKM

VAYDPDERIAAHQALQHPYF
 .|||. || | ||||||||
LCYDPKKRISAEQALQHPYF
Kinase MOK.AA CDC2 4-285 33 7e-81 248.21 In-house 1-301 (301) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-301/301
Sequence Identity: 33% (103 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQ---VNNLREIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDMNIYELIR---GRR
|. | ||||||. .| | . .... . | |. .   |. .       .|||  |  |..|||| .||.|..     .| .. | .||.  .. .   . .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

YPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQD-VLKLGDFGSCRSV-YSKQPYT--EYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFY
..... ..  ||||... ... |...|.||| || ||||  . ..|..|||  | . . . .||    . |.|||||| || . .|.   |.|| ||.|.
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EI---ASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPFKKGSGIPLLTTN---------LSPQCLSLLHAMVAYDPDERIAAHQALQ
|.   ..  |||.|  | ||. ||  ..|||  ...   .|    . .||  | ...  .  |         | |....||  | .|||  || | .|||
EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

HPYF
||||
HPYF
Kinase MOK.AA Pkinase 4-285 30 5.9e-77 266.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-293/293
Sequence Identity: 30% (93 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQ-VNNLR--EIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDM-----NIYELIR-
|. ..|||.|.|..| | .   .|  .|.|..| | |. .. ....|  ||| ..||| ||||. |.... |  .... .. |....       ...|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

GRRYPL--SEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIK-QDVL----KLGDFGSCRS--VYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDL
 |. ..  ||. . .||||... |...|..|| |||.|||||||. ....    |..|||...     ... .| .  |.||.||| ....  |..| | 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSAGCVFYEIASLQPLFPGV----NELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQ
||.||..|| .. .|.|||     | .||. .|  . |.|      .    .  . ... .      .. .|.|. |....  . ..|| .|. |.|.||
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQ

HPYF
||.|
HPWF
Kinase MOK.AA CDK5 4-285 33 3.4e-62 195.13 In-house 1-287 (287) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-287/287
Sequence Identity: 33% (99 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESI-EQV--NNLREIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPL
|. . ||||||.  | | .    . ..| |.   | .|  | |    .|||  |. |  |.||  || |.   |   | |. | .|  .   .  .   .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRV--RLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIHSEK--KLTLVFEFCDQDLKKYMDSCNGEM

SEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILI-KQDVLKLGDFGSCRSV-YSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIA-S
. . |  .|||| | |   | . . ||| || | || |.  |||.|||  |      . |.  . | |||.|  |.    |.   |.||.||.| |.| .
DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA

LQPLFPGVNELDQISKIHDVIGTPAQKI---LTKFKQSRAMNFDFPFKKGSG-IPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF
..||||| .. ||  .| ...|||       .||  . ..   ..|   .      .. .|. . . ||. |  ..|..|| | .||.||||
GRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase MOK.AA Ciliate-E2 4-285 20 1.2e-55 189.49 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-365/365
Sequence Identity: 20% (82 aa)

YKAIGKIGEGTFSEVMKMQSLRDGN-----------------------YYACKQMKQR-FESIEQVNNLR----------EIQALRRLNPHPNILMLHEV
|| | |||.|.|. | |..  ....                       .|| |.||..  |.|.|....           . . . ... ||||. ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VFDRKSGSLALICELMDM-NIYELIRGRR----------YPLSEKKIMHYMYQLCK---------------SLDHIHRNG-IFHRDVKPENILIKQDVLK
  . .  .. |. |. .  . ...|. ..           ...||.| ..|.|...                | ..| .. |.||| ||||||.    .|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

LGDFGSCRSVYSK----------QPYTEYIS-----------------------TRWYRAPECLLTDGF--------YTYKMDLWSAGCVFYEIASLQPL
. ||| .. .  .          . |..  .                       |  | ||| |   .         |.|| |.||.|...||  . .| 
IIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPFKKGSGIPLL--------TTNLSPQCLSLLHA----MVAYDPDERIA-AHQALQHPYF
|                          ..|    ..|||...     ..        . ..|..|  |.      |  .||..||  . |.|.||.|
F--------------------------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MOK.AA CDKL 4-220 36 1.7e-53 181.24 In-house 1-218 (286) Show / Hide 
Range on Protein: 4-220
Range on HMM: 1-218/286
Sequence Identity: 36% (81 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQ-RFESIEQVNNLREIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSE
|  .||.|||    |||      | . | |  |  . . ..  . .|||  |. |  |.||  | ||   |. . | |  | .| .. ..   .   . |
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLK-HENIVNLIEVF--RRKRKLHLVFEYCDHTVLHELEEYPNGVDE

KKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIK--QDVLKLGDFGSCRSVYSKQP--YTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASL
.... ||.|..|.... | . . |||.|||||||   ....||.|||  |   .|.   ||.|  |||||||| |. |  |    |.|..|||. | .. 
HVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDG

QPLFPGVNELDQISKIHDVIGT
|||.|| ...||  .|  ..|.
QPLWPGQSDIDQLYHIQKCLGP
Kinase MOK.AA CDK-Unclassified 45-221 30 1.4e-48 157.85 In-house 53-258 (324) Show / Hide 
Range on Protein: 45-221
Range on HMM: 53-258/324
Sequence Identity: 30% (64 aa)

VNNLREIQALRRLNPHPNILMLHEVVFDRKSGS-----------LALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPEN
.. .|||  |...| | ||. . ... |.   |           . .. | |.   |      ||.||   |  .| |. ...  .| |.| |||.||.|
ITDQREISCLQNCN-HMNIIKFMDMHYDHDRCSKNPYYDNLHPSFYMVMEYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQN

ILI-KQD-----VLKLGDFGSCRSVY-------------SKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKI
|.|  ..     .||..|||. .  .             . | |.  .||||||||| |. .  |..  | ||.||.. |.    |.|.| .|..|...|
IMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRTEIEQMHHI

HDVIGTP
 ...|||
FKMLGTP
Kinase MOK.AA TyrKc 4-285 21 1.3e-12 -18.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRL-NPHPNILMLHEVVFDR-----KSGSLALICELMDM-NIYELIRGR
 . . |.||| | ||.| .        | | .|     .|    .||.. ...|   ||||. |. |. .       .. | .. |.|.  .  . .| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDF--MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

RYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQDV-LKLGDFGSCRSVYSK-------QPYT------EY--ISTRWYRAPECLLTDGFYT
|  |. |.  ....| ..  ...|.... |||    |.|.. .   | .||| .| .|..       . |.      .   .  ||. ||||.  .| .|
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKFT

YKMDLWSAGCVFYEIASL-QPLFPGV----NELDQISKIHDVIGTPAQKIL----TKFKQSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMV----A
 | | || | . .|| .. |.  ||.     . ... .  .  . . |                                   .. | . .. .     .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------FVCCPDEMYQIMKQCWH

YDPDERIAAHQALQHPYF
.||..|    .   | .|
EDPEDRPTFSEI--HECF
Kinase MOK.AA CDKL 253-285 38 1.6e-10 32.22 In-house 253-286 (286) Show / Hide 
Range on Protein: 253-285
Range on HMM: 253-286/286
Sequence Identity: 38% (13 aa)

NLS-PQCLSLLHAMVAYDPDERIAAHQALQHPYF
|.| .  |......   |||||. . |...||||
NKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase MOK.AA Pkinase_Tyr 48-198 27 3.4e-10 35.16 Pfam 51-210 (270) Show / Hide 
Range on Protein: 48-198
Range on HMM: 51-210/270
Sequence Identity: 27% (44 aa)

LREIQALRRLNPHPNILMLHEVVFDRKSG-SLALICELMDM-NIYELIRGR---RYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIK-QDVL
.||.. .. |  ||||. |. |. |..   .. .. |.|   . ..  | .   . ||. | . .. .| .| ... ..... |||.   |.|.. . | 
MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVV

KLGDFGSCRSVYSKQPY-----TEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASL
| .||| .| .|..  |        .  .|. ||||. .   .| | | || | . .|| ..
KICDFGLARDIYNDDYYYRKRGGGKLPIKWM-APECINYGK-FTTKSDVWSFGVLMWEIFTY
Kinase MOK.AA CDK-Unclassified 253-285 34 3.8e-07 19.42 In-house 287-324 (324) Show / Hide 
Range on Protein: 253-285
Range on HMM: 287-324/324
Sequence Identity: 34% (13 aa)

NLSPQCLS-----LLHAMVAYDPDERIAAHQALQHPYF
|..| |..     ..  ||.|.|..|  . ..||||.|
NRFPKCKHASENNCEFQMVMYQPYNRWKCMEILQHPWF
Kinase MOK.AA CDK-Unclassified 4-20 52 0.000921 8.1 In-house 1-17 (324) Show / Hide 
Range on Protein: 4-20
Range on HMM: 1-17/324
Sequence Identity: 52% (9 aa)

YKAIGKIGEGTFSEVMK
|. . |.||||| .| |
YRMQCKYGEGTFGCVCK