Gene p70S6K (Human)

p70S6K

Species: Human
Alias: p70(S6K)-alpha, p70s6k, S6K, STK14A, S6K1, p70S6K, RPS6KB1, PS6K, p70-alpha, p70-S6K
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 17q23.2,

Classification

Group: AGC
Family: RSK
Subfamily: RSKp70

Sequence

Name Sequence Type Origin Length Description Download
p70S6K.NA RNA Sugen Kinome 5332 None Fasta, JSON
p70S6K.AA Protein Sugen Kinome 525 None Fasta, JSON
p70S6K.kin_dom Protein Kinase Domain Sugen Kinome 262 None Fasta, JSON

Protein domain

Protein domains of p70S6K.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase p70S6K.AA p70 91-352 73 7.50000000001e-223 746.63 In-house 1-299 (299) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-299/299
Sequence Identity: 73% (219 aa)

FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERNILEEVKHPFIVDLIYAFQTG
||||.||||||||||||||||||..||||.|||||.||.||||.||||||.                         ||||||||||||||.||.|||||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

GKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTV----------THTFCG
||||||||||.||||||.|||.||.|||||||||.||..||.||||.|||||||||||.|||.||||.||||||||||||||.|          ||||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK--LNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF
||||||||||||.|||.||||||||.||||||||.|||||||||||||||||.|  |.||||||.|.|||.||||||....|.||||.||...|.||||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase p70S6K.AA AGC 91-352 37 2.8e-196 513.35 In-house 1-395 (395) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-395/395
Sequence Identity: 37% (149 aa)

FELLRVLGKGGYGKVFQVRKVTGA---NTGKIFAMKVLKKAM-IVRNAK-DTAHTKAE------------RNILEEVK----------HPFIVD-LIYAF
||.|.|.|||..|||..|||..|     |||..|||||||.  ||.. | . .||..|            |||||...          |||||  | |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTGGK--LYLILEYLS---------GG-ELFMQLE---REGIFMEDTACFYLAE-------ISMALGHLHQ-KGIIYRD-LKPENIMLNHQGHVKLTDFG
|.  .  ||...||..         || |||..|    .||.| |..|.||.||       | .|| .||. .|||.|| ||||||.|...||.||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKESIHDG--------------------------------------------------TVTHTFCG--TIEYMAPEILMRSGHNRAVDWWS--LGALMY
|||| . ||                                                    |.||||  | ||||||||    ...|.||||  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

DMLTGAPPFTGEN----------RKKTIDKIL------KCKLNLP----------PYLTQEARDLLKKLLKRNAASRLGAGPGD-----AGEVQAHPFF
 |||| |||.|.|          .... .||.      ..|. .|          .....||.||.||||... . |||.|..|     | |...||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase p70S6K.AA RSK 94-352 58 4.90000000001e-179 601.07 In-house 1-278 (278) Show / Hide 
Range on Protein: 94-352
Range on HMM: 1-278/278
Sequence Identity: 58% (162 aa)

LRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVK-HPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGI---
|.|||.|||||||..||.|. .||.|.||||||||.||...|||.||..||||||... |||||.| |||||.||||||.||..|||||. |..|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNH---QGHVKLTDFGLCKE-SIHDGTVTHTFCGTIEYMAPEILM----RSGHNRAVDWWSLGA
|.||.||||.|||..|. ||||.|||.||||||||....   .||.||||||.||. .....  |.|||.||||||||.|.    ..||..|.||||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMYDMLTGAPPFTG---ENRKKTIDKILKCK--LNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF
|||.||||.|||.|   .|||.....|.|.|  |..|  .||.|||.||..|.|.|. . |||.||.|| |...||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase p70S6K.AA SGK 91-352 47 1.3e-150 468.69 In-house 1-283 (283) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-283/283
Sequence Identity: 47% (134 aa)

FELLRVLGKGGYGKVFQVRKVTG---------------ANTGKIFAMKVLKKAMIV------RNAKDTAHTKAER-NILEEVKHPFIVDLIYAFQTGGKL
|..| |.|||..|||.||...                    .|..|||||.|. |.       . |   |..||| .||  .|||||| | |||||  ||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRS
|. ..|. |||.|  | ||..| || | || |||  ||..|| . |||||||||||.| ||||..||||||||| | . . | ||||| ||.|||.|   
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF
.| |.||||.||...|.|..|.|||   |..   |.|.. .|..||. . .|.||.. ||...   |||.   |..|.. ||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase p70S6K.AA Akt 91-352 51 2.3e-147 474.18 In-house 1-264 (264) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-264/264
Sequence Identity: 51% (138 aa)

FELLRVLGKGGYGKVFQVRKVTGANTGKIF-AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGI
|..|.||||| .||||.|.|    .|.|.. ||||||| .|. .    .|||.|||||. ..||||| | |.|||  |||....| .|||||  | |...
FDFLKVLGKGSFGKVFLVKK---KDTQKWYYAMKVLKKDYIIQKN-QVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR

FMEDTACFYLAEISMALGHLHQKGIIYRD-LKPENIMLNHQGHVKLTDFGLCKES-IHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWS-LGALMYDM
| ||.| || |||. |..|||.|.||||| ||||||.. ..||..|||||||||  | |. .| ||||| ||.|||||   || .|||||. ||..|| |
FSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEM

LTGAPPFTGENRKKTIDKILKCKLNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF
..|.|||  .....  .||. .... |  ... .|..||...||...   |||.||.|| |...||.|
MCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase p70S6K.AA RSK 91-352 41 1.8e-130 439.75 In-house 1-271 (271) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-271/271
Sequence Identity: 41% (113 aa)

FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIF
.||....|.| ..||. ..|...  |.. .|||..||| ..  .||.  ...||.||... ||||| | |.||..||.|.|.. . ||.||  | ... |
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRD--VKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF

MEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQ----GHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDM
 |. ..||.|||  |. .||..||..|||||||| .  .    ||.|..|||. |... .   . |||.|..|||||.|.| || .|.||||.|.||| |
SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM

LTGAPPFTGENRKKTIDKILKCKLNL-------PPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF
|||..|| . .|. . ..|.. || .       . ....|| ||| ..|.|. . |||||| .. ..  ||.|
LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase p70S6K.AA RSK-Unclassified 91-352 43 6.4e-124 391.32 In-house 1-283 (283) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-283/283
Sequence Identity: 43% (125 aa)

FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLE--REG
|.  | .|.|  |||. |||    .| .|.|||||.|  ..|  | .     |.||.   .||||| | ..|||  .|||..||  ||..|  |   .| 
FIKHRLIGQGDFGKVYLVRK---KDTQQIYAMKVLHKHKMIRHNK-IKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEK

IFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKES---------------------IHDGTVTHTFCGTIEYMAPEILMR
 | || . ||..|. .|| .|| ...|||||||.||.| . |||.||||.| ..                      . .|. |  |||| ||.|||.. |
CFCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRR

SGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF
 || .||||| || .|| || | ||. |.|.  |   |.| .. .|   |. ...|||.||||.|| | |||.. ||| .. .||||
CGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase p70S6K.AA AktR 91-352 45 2.4e-112 379.55 In-house 1-268 (268) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-268/268
Sequence Identity: 45% (124 aa)

FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKK-AMIVRNAKDTAHTKAERNILE-EVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG
|.....||||..|||. |.|    ...|..|||..||  .| ||...  ||  ||||.| ...||||| | |.|||  ||..|.||  |||||  | ...
FHVYKCLGKGAFGKVYLVQKKR--DNQKQYAMKMIKKKKIIERNQMH--HTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKK

IFMEDTACFYLAEISMALGHLHQK-GIIYRDLKPENIMLNHQGHVKLTDFGLCK-ESIH-DGTVTHTFCGTIEYMAPEILMR-SGHNRAVDWWSLGALMY
 | |..| || |.|  || .|||.  |||||||||||.|   ||||.||||| | . .  .  ....|||| ||||||....  |||..||||..|.. |
KFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIY

DMLTGAPPFTGENRKKTIDKILKCK---LNLPPYLTQEARDLLK-KLLKRNAASRLGAGPGDAGEVQAHPFF
 |.|| |||. .|..  ..||...     . |.|......||.. |||..|   ||| .  .. |.  ||.|
EMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase p70S6K.AA PKA 91-352 42 3.9e-110 372.2 In-house 1-263 (263) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-263/263
Sequence Identity: 42% (114 aa)

FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVD-LIYAFQTGGKLYLILEYLSGGELFMQLEREGI
||....||.| .|.| ..|. .   .|...|||.|||. |||  | . |.. |.||| ..||||||  ... ||.  .||...|| .|||.|  | ..| 
FEIIQTLGTGSFGRVMLCRHKH---SGNYYAMKMLKKQEIVR-LKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGR

FMEDTACFYLA-EISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRS-GHNRAVDWWSLGALMYDML
| ...|.|| | .|  ||  ||.. |||||||||||... .||.|.||||  |. . |  .| | ||| ||.||||. .. ||...||||.|| | | ||
FSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEML

TGAPPFTGE--NRKKTIDKILKCKLNLPPYLTQEA---RDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF
.| |||. .  .  .. .||...|.. |..... |   .||.|||| ..   |.|   ...  .  |..|
AGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase p70S6K.AA MSK 94-347 41 9.1e-110 370.97 In-house 1-277 (277) Show / Hide 
Range on Protein: 94-347
Range on HMM: 1-277/277
Sequence Identity: 41% (116 aa)

LRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV-KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFME
|.|||.|||||.| .||... .|||..|||.|.|| .|  .| ..||..|| .|| . .||.|| | ||||.  ..||..||..|||||  . . . | |
LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDE

DTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQ---GHVKLTDFGLCKESIHD-GTVTHTFCGTIEYMAPEILMR-----SGHNRAVDWWSLGALM
. . ....|. ||. |.||||||.||||||||..  .   |||||.|||. ..   |    ....|.|..|||||.| |     .|.. |.||||||...
SECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVIL

YDMLTGAPPFT--GENRK------KTIDK-ILKCKLNLP----PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQ
| ||||. ||.  .. |.      . | | |.|.. ..|        ..|.||...|| .. . |||... .| |. 
YTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase p70S6K.AA S_TKc 91-352 36 4.90000000001e-109 369.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-231/231
Sequence Identity: 36% (100 aa)

FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSG--GELFMQLEREG
.|.||..|||..|||...|..    ||.|.|.|..|            |.. |..||.. .||.|| |...||. ..||...||..|  |.||  ... |
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

I------FMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNR-AVDWWSLGA
       | | .|.||...|  || ..|..|||.||||||||.|..  |.|..||||...        .||||| .|||||.|   |... ..||||.| 
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGE--VQAHPFF
..| ||.| |||   . .....||.          ..||.|...|.|... . |..|    ..|  . .||.|
ILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase p70S6K.AA Pkinase 91-352 30 8.2e-92 316.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-293/293
Sequence Identity: 30% (93 aa)

FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDT---AHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGG----ELFMQ
....|..|.|..|.|   .| .  .||||.|.|..||  .  . . |   .   .|  |. ...||.|| |...|......|...||. ||    .||  
YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

LE--REGIF--MEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHV----KLTDFGLCKES-IHDGTVTHTFCGTIEYMAPEILM-RSGHNRA
..  |.| |   |....||. .|  .| ..|..|||.||||||||.....||.    |..||||.|   .  .. ..|||||..|||||... .... ..
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

VDWWSLGALMYDMLTGAPPFTGE------NRKKTIDKILKCKLNLPPYLT---------------------QEARDLLKKLLKRNAASRLGAGPGDAGEV
||.||.| ..| ||.| ||| |.      . .. |..|....|  . . .                     .|..|..|..|... ..|..     | ..
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQI

QAHPFF
  ||.|
LQHPWF
Kinase p70S6K.AA S_TK_X 353-415 40 4.6e-29 103.78 SMART 1-79 (79) Show / Hide 
Range on Protein: 353-415
Range on HMM: 1-79/79
Sequence Identity: 40% (32 aa)

RHINWEELLA--RKVEPPFKPLLQ----SEEDVSQFDSKFTRQTPVDSPDDSTLSESANQV----------FLGFTYVA
|.|.|. |..  ...|||||| ..    |..|.|.|| .||..||...|||..||.|..|           |.|||||.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase p70S6K.AA Pkinase_C 372-417 40 2.7e-15 57.07 Pfam 1-46 (46) Show / Hide 
Range on Protein: 372-417
Range on HMM: 1-46/46
Sequence Identity: 40% (19 aa)

LLQSEEDVSQFDSKFTRQTPVDS-PDDSTLSESANQVFLGFTYVAPS
 . |..|.| ||  ||...|.|. ||.. .|....  | |||||.|.
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase p70S6K.AA TyrKc 91-352 20 5e-14 4.17 SMART 1-280 (280) Show / Hide 
Range on Protein: 91-352
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV--KHPFIVDLIYAFQTG-------GKLYLILEYLSGGELF
 .|...|| | .|.|.. .           | |.||.          .    | .|. ..  .|| || |. .  ..       . |....|| ..| | 
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

MQLEREGI-FMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHD-------GTVTHTF--CGT----IEYMAPEILMR
  | . .  .  .. . .   |.    .||.|..| |||   |........|| .||||...  .|        . ...   .|     |  |||| .. 
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

SGHNRAVDWWSLGALMYDMLT-GAPPFTG-----ENRKKTIDKILKC-KLNLPPY--------LTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF
.  . . | || | .|. ..| |..|  |      . .  | .. .   .  ||.         ..|  .. |.  ......|           . | .|
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF-------SEIHECF
Kinase p70S6K.AA Pkinase_Tyr 91-248 23 4e-07 24.74 Pfam 1-166 (270) Show / Hide 
Range on Protein: 91-248
Range on HMM: 1-166/270
Sequence Identity: 23% (41 aa)

FELLRVLGKGGYGKVFQVRKV-TGANTGKIFAMKVLKKAMIVRNAKDTAHTKA--------ERNILEEV-KHPFIVDLIYAFQ-TGGK--LYLILEYLSG
 .....||.| .|.|.. .    . ||.   | |.||         ..|. ..        | .|. .  .|| || |. .    |.   .|...||  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH

GELFMQLER----EGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGT
| |   | .    .. .   . . . ..|.... .|..|..| |||   |........|| .||||..   .|..
GDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDY