TBCK

Species: Human
Alias: MGC16169, TBCK, HSPC302
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 4q24,

Classification

Group: Other
Family: TBCK

Sequence

Name Sequence Type Origin Length Description Download
TBCK.NA RNA Sugen Kinome 3923 None Fasta, JSON
TBCK.AA Protein Sugen Kinome 893 None Fasta, JSON
TBCK.kin_dom Protein Kinase Domain Sugen Kinome 256 None Fasta, JSON

Protein domain

Protein domains of TBCK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TBCK.AA TBCK 18-273 40 4.5e-175 587.9 In-house 1-346 (346) Show / Hide
Range on Protein: 18-273
Range on HMM: 1-346/346
Sequence Identity: 40% (139 aa)

ALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGK--HERLVVVAEHCERSLED----LLRERKPVSCSTVLCIAFEVLQGLQYMNKHG
...||.|..||||.|||....|||||.||...||.||||.|.||||  |||..||.||....|||    ......|..||..|||....|.||.||.||.
QEKHDRCCINGLPVTPNAKQMLGRFQYLKSLQHPNLCQYLDFSRGKIHHERMIVVMEHYKMNLEDQIEIYAKRHTPKDCSQILCIYYQILCGLSYMHKHH

IVHRALSPHNILLDRKG----HIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIFKTTDHMPSKKPLP-------SGPKSDVWSLGIILFELCVG
||||.|.||||.||..|    |.|||..||||||.||.||.||||||.|.|||.|.||..|||||||...|||       |.|||||||||.|..|.|.|
IVHRFLHPHNIYLDDNGNQKLHVKLANYGLYHMTNHGKDVPFPIGYPRYMAPERILQGEMKTTDHMPPTNPLPPKTTNLSSNPKSDVWSLGCIMLEICLG

RKLFQSLDISERLKFLLTLD------------------------------------------------------------CVDDTLIVLAEEHGCLDI--
..|.|.|..||.|.......                                                            |.......||.||.|...  
ICLWQELTLSEVLNKIMHYGTHSTTQSFNSISKSFEQCELKKTIINEKQHEEYEEYDDDEDISEEEKEKRIKDIKLNDQDCMNHFMEDLAREHQCHQRSN

-----------IKELPETVIDLLNKCLTFHPSKRPTPDQLMKDKVF
           .....|..|....|||...|.|||.|..||....|
SGSSNSNIGIPYHQMCEWLIQIIRKCLQMCPMKRPSPTELMEHPMF

Kinase TBCK.AA Ciliate-E2-Unclassified 77-273 20 5.9e-29 97.58 In-house 107-352 (352) Show / Hide
Range on Protein: 77-273
Range on HMM: 107-352/352
Sequence Identity: 20% (54 aa)

SLEDLLRERKP-----------------VSCSTVL-----CIAFEVLQGLQYMNKHG-IVHRALSPHNILLDRKG---HIKLAKFGLYH-----------
.|.. ...||                  ...  ..      .. ..||||.|. . . |.|| . | |||.| .|   .||.. ||.             
DLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTN

----MTAHGDDVDFPI-GYPSYL----APEVIAQGIFKTTDHMPSKKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISE------------RLKFLLT
    |    ..    . | |.|.    ||||. .    ..             |.|.||||.||.|.. |.  |.. .  .            . | |. 
QQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----------YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

LDCVDDTLIVLAEEHGCLDIIKELPETVIDLLN----KCLTFHPSKRPTPDQLMKDKVF
  .  .. .  ...     | | ......|..|    |.|   |.||.|..|...   |
NIKQKNIQFPKFPWQQ---IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

S_TKc TBCK.AA S_TKc 1-273 22 6.6e-28 99.96 SMART 1-231 (231) Show / Hide
Range on Protein: 1-273
Range on HMM: 1-231/231
Sequence Identity: 22% (68 aa)

MFPLKDAEMGAFTFFASALPHD---------VCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCER---SLEDLLRERKP-
   |.    |||     .  ..         .            ..|.   ||||   || .... |. .   ..| .| |.|.    .| |....|.. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----VSCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIFKTTDHMPSKKPLPSG
      .  .. ... .....|.|. .|||.|| | | |||||.  |||.. |||          .  .| | |.||||.                 . |
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-----------------GYG

P-KSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLDIIKELPETVIDLLNKCLTFHPSKRPTPDQLMK-------DKVF
. |.|.||.|.||.|...|. .|.  .. . .| ..                         .. ..|...|||.. |.||||  ....       .  |
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase TBCK.AA Ciliate-E2 43-273 19 1.9e-27 91.26 In-house 84-365 (365) Show / Hide
Range on Protein: 43-273
Range on HMM: 84-365/365
Sequence Identity: 19% (59 aa)

QILKTITHPRLCQYVDISRG-KHERLVVVAEHCER-SLEDLLRER-----------KPVSCSTVLCIAFEVLQ---------------GLQYMNKHG-IV
.||... || ......     . . .  | | |.  .|.|.....           |. ..  .. |  ..||               .|.|. . . |.
NILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNII

HRALSPHNILLDRKGHIKLAKFGL-----------------YHMTAHGDDVDFPIG----------------YPSYLAPEVIA------QGIFKTTDHMP
|| . | |||.     ||.. |||                 . ..  . | .  .|                 | |.|||..       |          
HRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ----------

SKKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLD--IIKELPETVIDLLNK----CLTFHPSKRPT-PDQL
 .|  . . |.|.||||.||.|.. |.  |    . . ..  . ..| . ..  .  .   ..  . |.... ..||..|    .|   |.||.| ..|.
-QKQKGYDYKCDIWSLGVILYEMLFGKPPF----QQQIKQCKIDFPCPEWQKD-TQ-CI-QCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI

MKDKVF
.. . |
LNHPWF

Kinase TBCK.AA Pkinase 43-214 29 2.4e-26 94.25 Pfam 52-228 (293) Show / Hide
Range on Protein: 43-214
Range on HMM: 52-228/293
Sequence Identity: 29% (56 aa)

QILKTITHPRLCQYVDISRGKHERLVVVAEHCER-----SLEDLLR--ERKPV--SCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHI---
||.| . ||  ... |. .  . .. .| |.||      .| |...  .....  |  .. ... ..|.||.|. ..||.|| | | |||.|..|||   
QIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDAC

-KLAKFGL-YHM-TAHGDDVDFPIGYPSYLAPEVIAQGIFKTTDHMPSKKPLPSGPKSDVWSLGIILFELCVGRKLFQSL------DISERLK
 |.. |||  .. . ..   . . | | |.|||||              .  . |||.|.||.|.||.|.. || .|..       |  ....
VKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-------------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMIC

Kinase TBCK.AA TKL 96-269 18 9.6e-22 75.08 In-house 137-362 (364) Show / Hide
Range on Protein: 96-269
Range on HMM: 137-362/364
Sequence Identity: 18% (42 aa)

IAFEVLQGLQYMNKHG--------IVHRALSPHNILLDRKGH--------------IKLAKFGLYH-MTAHGD-------------------DVDFPIGY
.| .. .|..|.  ..        |.|| | ..|||.|....              .|.. |||   |. .|.                       ..| 
WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGT

PSYLAPEVIAQGIFKTT----DHMPSKKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLD----------II
| ..||||. . .. |     |     | ..  .|.||.| ||.|.|.. ... .. .. .... .       .  ....  ..  ..            
PRWMAPEVLRGQMNYTEKVGIDE--FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPC

KELPETVIDLLNKCLTFHPSKRPTPDQLMK
.  |. ...|. .|    |.|||. ....|
PDCPPSMKKLMQDCWDHDPEKRPSFQEILK

Kinase TBCK.AA STE 43-201 23 3.6e-20 67.99 In-house 80-265 (359) Show / Hide
Range on Protein: 43-201
Range on HMM: 80-265/359
Sequence Identity: 23% (46 aa)

QILKTIT--HPRLCQYVDISRGK------HERLVVVAEHCE-RSLEDLLRERKPVSC--------------STVLCIAFEVLQG-LQYMNKHGIVHRALS
.|.|     ||   .| .    .      .. | .. |...  ||.|...... . .              | . .|....|.| |.|  .|.|.|| . 
KIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIK

PHNILLDRKGHIKLAKFGLYH-MTAHGD------------DVD----FPIGYPSYLAPEVIAQGIFKTTDHMPSKKPLPSGPKSDVWSLGIILFELCVGR
| ||||     .||. ||.   .| ...            . .      .| | . ||||| |.  . .         . . |.|.||||. . |.. |.
PANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R-------DKGYDTKCDIWSLGCTIIEMATGK





Kinase TBCK.AA STE20 95-197 33 2.4e-14 49.12 In-house 121-220 (288) Show / Hide
Range on Protein: 95-197
Range on HMM: 121-220/288
Sequence Identity: 33% (36 aa)

CIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHIKLAKFGLYHMTAH-----GD-DVDFPIGYPSYLAPEVIAQGIFKTTDHMPSKKPLPSGPKSDVW
.|  ||||||.|  ...|.|| .   ||||. .| .||| ||.  .  .      .   .  .| | ..|||||..  ..  ..         . |.|.|
YICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPDKGY---------DYKCDIW

SLGIILFEL
|||| . |.
SLGITAIEM

Kinase TBCK.AA ULK 43-137 21 3.6e-14 45.96 In-house 62-188 (329) Show / Hide
Range on Protein: 43-137
Range on HMM: 62-188/329
Sequence Identity: 21% (27 aa)

QILKTIT--------HPRLCQYVDISRGKHE-RLVVVAEHCER-SLEDLLRERKPVSCST----------VLCIAFEVLQGLQYMNKHGIVHRALSPHNI
.|.|..         ||  ... |... ...  .  . | |.   ||... ..|. . .|          .. .    |.|.....||.|.|| . | ||
KIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNI

LLDRK------------GHIKLAKFGL
|.. .            |..|.| ||.
LIHNGQPKTDSKKVHPNGVLKIADFGF

Kinase TBCK.AA ULK 43-137 21 5.9e-13 42.36 In-house 62-184 (324) Show / Hide
Range on Protein: 43-137
Range on HMM: 62-184/324
Sequence Identity: 21% (27 aa)

QILKTIT---HPR--LCQYVDISRGKHE-RLVVVAEHCER-SLEDLLRERKPVSCST----------VLCIAFEVLQGLQYMNKHGIVHRALSPHNILLD
||.|..    ||    ... |... ...  .  . | |.   ||... ..|. .  |          .. .    ..|.....||.|.|| . | |||. 
QIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIH

RK------------GHIKLAKFGL
 .            |..|.| ||.
NGQPKTDSKKVHPNGVLKIADFGF

Kinase TBCK.AA CMGC 62-137 18 1.5e-12 36.62 In-house 119-250 (513) Show / Hide
Range on Protein: 62-137
Range on HMM: 119-250/513
Sequence Identity: 18% (25 aa)

GKHE------RLVVVAEHCERSLEDLLRE----------------------------RKPVSCSTVLCIAFEVLQGLQ--YMNKHG--IVHRALSPHNIL
.||.       |  | |... .| .....                             |  .   .  ... .|.||   |. .|.  |.|| | | |||
DKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENIL

LDRK--------------------GHIKLAKFGL
.. .                    |..|.. |||
INHNCELITRMMWKSEDWNPCQKNGRLKICDFGL

Kinase TBCK.AA PEK 72-137 20 1.3e-11 35.92 In-house 363-478 (655) Show / Hide
Range on Protein: 72-137
Range on HMM: 363-478/655
Sequence Identity: 20% (24 aa)

EHCE-RSLEDLLRERK--------------------------------------------PVSCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDR
|.||  .|.|......                                             ..  ... |. ..| ||.|.  .|..|| | |.||.||.
EYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIFLDC

KGH-----IKLAKFGL
.|.     .| . |||
DGQHHQMQVKIGDFGL

TyrKc TBCK.AA TyrKc 1-272 16 5.6e-11 -45.21 SMART 1-280 (280) Show / Hide
Range on Protein: 1-272
Range on HMM: 1-280/280
Sequence Identity: 16% (54 aa)

MFPLKDAEMGAF---------------TFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTI--THPRLCQYVDISRGKH------ERLVVVAEHCER-
   .|    |||               .  ..|                   ..   .|.. .   || . . . . . .       | | .| |...  
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

SLEDLLRERKP-VSCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHIKLAKFGL---------------YHMTAHGDDVD--FPIGYPSYLA
.| | ||...| .. .. | ... . .| .|  .....|| |   |.|.......| . |||               | ... ... .  .||     .|
DLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI---RWMA

PEVIAQGIFKTTDHMPSKKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLDIIKE--------LPETVIDLL
||.|  |.|               .|||||| |. ..|..   .   . .| .        .. .. .| . .. . ... ..         |. . .. 
PECINYGKF--------------TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIM

NKCLTFHPSKRPTPDQLMKDKV
 .|  . |..|||  .. ... 
KQCWHEDPEDRPTFSEI-HECF

Kinase TBCK.AA CMGC 240-273 38 5.2e-09 24.78 In-house 480-513 (513) Show / Hide
Range on Protein: 240-273
Range on HMM: 480-513/513
Sequence Identity: 38% (13 aa)

KELPETVIDLLNKCLTFHPSKRPTPDQLMKDKVF
| ...  ||||.|.|.. |.||.|..| ..   |
KCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF

Kinase TBCK.AA Pkinase 240-273 32 1.3e-07 28.02 Pfam 260-293 (293) Show / Hide
Range on Protein: 240-273
Range on HMM: 260-293/293
Sequence Identity: 32% (11 aa)

KELPETVIDLLNKCLTFHPSKRPTPDQLMKDKVF
....|. .|....||.. |.||||..|..... |
HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase TBCK.AA STE 247-273 44 2.4e-07 22.12 In-house 331-359 (359) Show / Hide
Range on Protein: 247-273
Range on HMM: 331-359/359
Sequence Identity: 44% (13 aa)

IDLLNKCLTFHPSKRPTPDQLMK--DKVF
.| .||||.  |.||||..||.|   . .
KDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase TBCK.AA Pkinase_Tyr 43-137 23 4e-07 24.74 Pfam 55-157 (270) Show / Hide
Range on Protein: 43-137
Range on HMM: 55-157/270
Sequence Identity: 23% (24 aa)

QILKTI-THPRLCQYVDISRGKHER--LVVVAEHCER-SLEDLLRE----RKPVSCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHIKLAK
.|.|..  || . ... .   . |   . .| |...  .| | ||.    ..|.. .. |...... .|..|   ....|| |   |.|.......| . 
KIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICD

FGL
|||
FGL

Kinase TBCK.AA STE20 248-273 46 4e-06 18.89 In-house 263-288 (288) Show / Hide
Range on Protein: 248-273
Range on HMM: 263-288/288
Sequence Identity: 46% (12 aa)

DLLNKCLTFHPSKRPTPDQLMKDKVF
|...|||.  |.||||..||.| . .
DFVDKCLQKDPEKRPTASQLLKHPFI

Kinase TBCK.AA PEK 248-273 26 8e-06 15.39 In-house 630-655 (655) Show / Hide
Range on Protein: 248-273
Range on HMM: 630-655/655
Sequence Identity: 26% (7 aa)

DLLNKCLTFHPSKRPTPDQLMKDKVF
|.....|   |..||...|... . |
DFIQWMLSHDPQQRPSAQQILQHEFF

Kinase TBCK.AA ULK 184-201 50 1.4e-05 15.52 In-house 236-253 (329) Show / Hide
Range on Protein: 184-201
Range on HMM: 236-253/329
Sequence Identity: 50% (9 aa)

KSDVWSLGIILFELCVGR
|.|.||||.|..|. .|.
KCDIWSLGCIFYEMLYGK

Kinase TBCK.AA PEK 184-200 52 1.7e-05 14.25 In-house 574-590 (655) Show / Hide
Range on Protein: 184-200
Range on HMM: 574-590/655
Sequence Identity: 52% (9 aa)

KSDVWSLGIILFELCVG
|.|..|||||.||....
KVDMYSLGIIFFEMWYP

Kinase TBCK.AA ULK 184-201 50 1.8e-05 15.48 In-house 232-249 (324) Show / Hide
Range on Protein: 184-201
Range on HMM: 232-249/324
Sequence Identity: 50% (9 aa)

KSDVWSLGIILFELCVGR
|.|.||||.|..|.  |.
KCDIWSLGCIFYEMLYGK

Kinase TBCK.AA CMGC 182-205 28 0.000233 9.21 In-house 313-344 (513) Show / Hide
Range on Protein: 182-205
Range on HMM: 313-344/513
Sequence Identity: 28% (9 aa)

GPKSDVWSLGIILFELCVG--------RKLFQ
... |.||.| |..|.  |        . ||.
TTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFP

Kinase TBCK.AA ULK 246-273 21 0.000472 10.14 In-house 302-329 (329) Show / Hide
Range on Protein: 246-273
Range on HMM: 302-329/329
Sequence Identity: 21% (6 aa)

VIDLLNKCLTFHPSKRPTPDQLMKDKVF
..||. ..|.. ...| . ..| . ..|
CKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase TBCK.AA ULK 246-273 17 0.000479 10.32 In-house 297-324 (324) Show / Hide
Range on Protein: 246-273
Range on HMM: 297-324/324
Sequence Identity: 17% (5 aa)

VIDLLNKCLTFHPSKRPTPDQLMKDKVF
..||. ..|.. ...| . ... . ..|
CKDLIRRMLQYDEKDRISWEEIFNHPWF

Kinase TBCK.AA Pkinase_Tyr 184-198 53 0.06883 7.02 Pfam 194-208 (270) Show / Hide
Range on Protein: 184-198
Range on HMM: 194-208/270
Sequence Identity: 53% (8 aa)

KSDVWSLGIILFELC
|||||| |. ..|..
KSDVWSFGVLMWEIF

TBC TBCK.AA TBC 469-671 24 5.8e-55 193.7 Pfam 1-240 (240) Show / Hide
Range on Protein: 469-671
Range on HMM: 1-240/240
Sequence Identity: 24% (60 aa)

PLMRGLTWAALLGV-----------------EGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQ-YD--ELLSSPEGHA-KFRRVLKAWVVSHPDLVYWQG
. .|.  |  |||.                 .   .  |  .....| |...||| |..|... ..  . .....|.  . |..|||. . .||. |.||
DQLRWQVWPYLLGYYPWMNGYYKRLYYQEKKQWYQMK-YQ-NNYHEPHPDYHQIEKDVHRTFPNHHHFFFFQNGQGQQVQLRNILKAYSNYNPDVGYCQG

LDSLCAPFLYLNFNNEAL-----AYACMSAFI--PKYLYNFFLKD-NSHVIQEYLT--VFSQMIAFHDPELSNHLNE--IGFIPDLYAIPWFLTMFTHVF
.  ..|||||. ...|       |. |.....   ..| .....| .  ..| ..   || . .  |||.| .|...  ..  |...|..||...|||.|
MNFIAAPFLYMYMMDEEDFQAEDAFWCFCQLMNENYHLRDYYTHDMPG-HLQRDFYFQVFEELLKKHDPKLYKHFQKDCLNIDPSMFATQWFMCLFTHCF

PLHKIFHLWDTLLL---GN--SSFPFCIGVA-IL-QQLRDRLL
|.  ....|| ...   |   . | | ...| ||  ..|. .|
PFETVLRIWDCFFFYCEGWNAKFFLFRFCLACILVKYHRQEIL

TBC TBCK.AA TBC 463-674 19 2.6e-48 167.74 SMART 1-310 (310) Show / Hide
Range on Protein: 463-674
Range on HMM: 1-310/310
Sequence Identity: 19% (61 aa)

ARVDIPPLMRGLTWAALLGV-------------------------EGAIHAKYDAIDKDTPIPT--------------------------------DRQI
 .  ||. .||  |  ||.                          . . . .|| . . ..  .                                . ||
WWQGIPHHYRGWVWWLLLNCQPMNTSNWERMQYMWDGENCYFPVNWDRCKDYYDRMLNQHCPCDHHHDNWQDIMMNNNDHECCWMSYWHFFQDCWHWHQI

EVDIPRCHQYDELLSSP---------------EGHAKFRRVLKAWVVSHPD--LVYWQGLDSLCAPFLYLNF-NNEALAYACMSAFIPKYLYNFFL----
|.|..|... ...  ..               ... . ||||.|. . .|.  ..|.||.  ..||.|. .   .|. |..|.....  |. .|.     
EKDLRRTFPNHPFFQFRMRYNQHCIMLHDQNGPHQESLRRVLYAYSWHNPEHIVGYCQGMNFIAAPLLLHMPCYDEEDAFWCFCKLMERYCPWFYFCDDQ

---KDNSHVIQEYLTVFSQMIAFHDPELSNHLNEI------------GFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLG----NSSFPFCIGVAILQ
   . . . ... . .|....  |||.|..||.|             .. |..||..||||.|.. |||. ....|| ...      . |.|||..|.|.
NCYTPDMMGMHWQMYQFDHLLQEHDPDLYKHLQEQDHHSMKWHFDHLEIDPSMYAFRWFLTCFAREFPLEDVCRIWDCYFFEYGRHGHPFLFCIALAMLK

QLRDRLLANG
..|. || . 
MHRQKLLQHD

Rhodanese TBCK.AA Rhodanese 782-883 24 1.6e-16 54.02 Pfam 1-102 (102) Show / Hide
Range on Protein: 782-883
Range on HMM: 1-102/102
Sequence Identity: 24% (28 aa)

TPSKKTKSS-KPKLLVVDIRNSEDFIRGHISGS-INIPFSAAFTAEGELTQG--PYTAMLQNFKGKVI-VIVGHVAKHTAEFAAH-----LVKMKYP-RI
||    .   .|.....|.|. |.. .||| |. .|||.         |..      ... . |.| | |...   .  . ..|      | .| || ..
TPEWLKEMMNDPDYVIIDVRPPEEYEKGHIPGAHVNIPW---------LEEEHDLEELGIKLDKDKPIIVVYC-HGNRSG-AWACLVWWMLKAMGYPPNV

CILDGGINKIKPT
 .||||... |  
YVLDGGWEAWKAE

RHOD TBCK.AA RHOD 780-886 21 1.7e-14 55.37 SMART 1-94 (94) Show / Hide
Range on Protein: 780-886
Range on HMM: 1-94/94
Sequence Identity: 21% (23 aa)

FKTPSKKTKSSKPKLLVVDIRNSEDFIRGHISGSINIPFSAAFTAEGELTQGPYTAMLQNFKGKVIVIVGHVAKHT-AEFAAHLVKMKYPRICILDGGIN
  .  .| ... ......|.|. ... .||| |.||||....               |.  |.| ....        .. |. | .. |....|||||..
V-PEWWKMLQN-EDCVIIDCRWPYEYEGGHIPGAINIPWDELLDR------------LGIDKDKPVIVYCRSGNRSAPRAAWWLREAGYKNVYILDGGWK

KIKPTGLL
. |  .. 
EWKRACPP