Gene DDB0229424 (Slime mold)

DDB0229424

Species: Slime mold
Alias: DdisK050, DDB0229424
External Links: DictyBase Link ,
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK-DD1

Sequence

Name Sequence Type Origin Length Description Download
DDB0229424.AA Protein None 1397 None Fasta, JSON
DDB0229424.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of DDB0229424.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229424.AA CDK-DD1 4-287 49 9.5e-238 742.79 In-house 1-379 (379) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-379/379
Sequence Identity: 49% (186 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALKIISVMNIENGLP-VEVKYLMKLRDCKNIVHLIEYFYSN-DDKLVMVFEYLEYDLWKFISPKNKYMTLSCT
.|||...|.|.||.|.||||....|.||||.....|.|.|.| ||.||||.||.||||||||..||.. ..|.||||||.|.|||||.|....||.|.|.
YQIISKCGQGIYGSVFKAIHKITHCMVALKNFKDWNQEDGEPKVECKYLMQLRHCKNIVHLIDHFYNFKNSKYVMVFEYFEHDLWKFMSNHQCYMSLPCI

KFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDLKIADFGFTTYIGN---PHLAHQVISLFYRPPELLMGSRNYGPEVDIWSVGCIIVEMLTGFYMF
|.|.||||||..|.|.|.|||.||||.|||||.|.||||.|||||||...   .|..|||.||.||||||||||..||||.|.||||||..||.|.||||
KCFFHQLLEGINECHNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSHQVVSLWYRPPELLMGSCQYGPEIDMWSVGCILMEMITNFYMF

AGSNDSLQLELIFKTFGTPTEKNWPGISKLSGYSPYLGSK----------SKKYPSKS---------------------------LKDIS----------
||||...|||||.|..|.||||||||.|.|.||..|....          ||.|||..                           ...||          
AGSNEQQQLELICKLCGCPTEKNWPGVSQLQGYNQYFHKQQQQQQNENNYSKQYPSRNRNNNNNNNNNNNNNNNNNNNNNNNNNKYNNISTSCLQSPSSS

------------KFKS---------FSN----------------------STLDIILRMLTLCPKNRISTKEALNHPWF
            .|||         |||                      |.||.|.||||||||.||.|||||.||||
PPIGGYASSLSTDFKSNEYNGYNQTFSNEDCLAISQKKLIDKFPHLVLLPSFLDLIERMLTLCPKKRINTKEALQHPWF
Kinase DDB0229424.AA CDK 4-287 35 1.3e-136 439.68 In-house 1-284 (284) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-284/284
Sequence Identity: 35% (116 aa)

FQIIELIGSGSYGKVYKAIHNLSK-----CTVALKIISVMNI----E-NGLP----VEVKYLMKLRDCKNIVHLIEYFYSN----------DDKLVMVFE
....| || |.||.||||.. ...       |||| | . |     |  |.|     |...|..|  ..||| |.. ....          . ||.||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YLEYDLWKFISPKNKYMTLSCTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFD-----LKIADFGFTTYIGN------PH--LAHQVISLFYRPP
|...||.|...           | ...|||.||. .||..||| |.||.|.||| .       |||||||.    |.      |   . |.|. | ||.|
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ELLMGSRNYG--PEVDIWSVGCIIVEMLT---GFYMFAGSNDSLQLELIFKTFGTPTEKNWPGISKLSGYSPYLGSKSKKYPSKSLKDISKFKSFSNSTL
|||.||..|.  ...|.||||||..||.|   . ..| |...  ||..||...|||||.||||..|| .|                              
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------------

DIILRMLTLCPKNRISTKEALNHPWF
| . .||...||.||| ..||.||.|
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase DDB0229424.AA CMGC 4-287 21 4.6e-115 379.75 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-513/513
Sequence Identity: 21% (113 aa)

FQIIELIGSGSYGKVYKAIH--------------NLSKCTVALKIIS---VMNI------ENGLP----VEVKYLMKLR----------------DCKNI
..||. ||.|.||.|||...              . ..  ||.|.|.     .       ..|.|     |.|.|..|.                . .||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VHLIEYFYSND----------------DKLVMVFEYLEYDLWKFISPKN---------------------------KYMTLSCTKFFIHQLLEGLD--EL
|.|...||...                ..| .||||...||...|  ..                           ||... . . ...|.|.||.   .
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYC

HSQK--IMHLDIKPSNLLINPR--------------------FDLKIADFGFTTYIGNP-----------------------HLAHQVISLFYRPPELLM
||..  |.| |.||.|.|||..                    . |||.|||. ......                       .. |.| ...||.||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GS---------RNYGPEVDIWSVGCIIVEMLTG--------FYMFAGSND-----------SLQLELIFKTFGTPT---------------EKNWPGISK
|.         ..|....|.||||||. ||.||         ..| |...             ||..|||..||||               |..||...|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

LSGYSPYLG-----------SK-----------SKKYPSKSLKDI----------------------SKFKS-----------FSNSTLDIILRMLTLCP
| .| ...            |.            ...| |..|..                       ||||            .   .| . .||.. |
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

KNRISTKEALNHPWF
..||. ..||.||.|
DKRITAEQALQHPYF
Kinase DDB0229424.AA CDC2 4-287 38 3.8e-92 283.46 In-house 1-301 (301) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-301/301
Sequence Identity: 38% (116 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALKIISVMNIENG--LPV----EVKYLMKLRDCKNIVHLIEYFYSNDDKLVMVFEYLEYDLWKFIS---PKNK
.| || || |.||.|||.... ..  |||| | . . . |   |     |  .| .|.| .||| | . ...   || ||||||..|| |.     ||||
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ--NKLYMVFEYLDMDLKKYMDMSIPKNK

YMTLSCTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDLKIADFGFTTYIGNPH--LA--HQVISLFYRPPELLMGSRNYGPEVDIWSVGCIIVE
.|...  | ...|.|.|.. .|...||| |.||.|.||.   ..||||||    .| |.  .   | |. | ||.||.|.|.. |  .||.||.|||. |
HMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAE

M---LTGFYMFAGSNDSLQLELIFKTFGTPTEKNWPGISKLSGYSPYLGSKSKKYPSKSLKD-ISKFKS--FSNSTLDIILRMLTLCPKNRISTKEALNH
|    |  ..|.|     ||  ||...|||.|..|||...|  | .  .   .. .|| ... ..| .     .  .|.. .|| ..| .||| ||||.|
MFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQH

PWF
|.|
PYF
Kinase DDB0229424.AA S_TKc 4-287 27 1.2e-89 305.05 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-231/231
Sequence Identity: 27% (83 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALKIISVMNIENGLPVEVKYLMKLRDCKNIVHLIEYFYSNDDKLVMVFEYLEY---DLWKFISPKNK-----Y
..|...||.|..|||||..|. ..  ||.|||.     . .  |.. |.|  ...|||.|...|..  |.| ||.||..    || ..|  ...     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MTLSCTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDLKIADFGFTTYIGNPHLAHQVISLFYRPPELLMGSRNYGP-EVDIWSVGCIIVEMLTG
..   ..|...|....|. .||..|.| |.||.|.|..    .||.|||. . .      ... ...|..||.|     ||. ..|.||.|||. |||.|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCG

FYMFAGSNDSLQLELIFKTFGTPTEKNWPGISKLSGYSPYLGSKSKKYPSKSLKDISKFKSFSNSTLDIILRMLTLCPKNRISTKEALN-------HPWF
   |       |....||  |                                         | . .|.| ..|.  |..|..  |||.       ||||
YPPFP------QMQMMFKKIG-----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0229424.AA CDK5 4-287 39 2.7e-82 259.78 In-house 1-287 (287) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-287/287
Sequence Identity: 39% (115 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALKIISVMNIENGLPV----EVKYLMKLRDCKNIVHLIEYFYSNDDKLVMVFEYLEYDLWKFISPKNKYMTLS
.. .| || | || ||||    ..  |||| .   .   | |     |.  |  |.  |||| |.    | . ||..|||..  || |..   | .| . 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIHS-EKKLTLVFEFCDQDLKKYMDSCNGEMDMH

CTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDLKIADFGFTTYIGNP--HLAHQVISLFYRPPELLMGSRNYGPEVDIWSVGCIIVEML-TGFY
  | |. ||| ||   |.....| | || ||||| .  || ||||     | |     | |. | ||||  ||||. |   .|.||.|||. ||  .|  
IIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRP

MFAGSNDSLQLELIFKTFGTPTEKNWPGISKLSGYSPYLGSKSKKYPSKS-LKDISKFKSFSNSTLDIILRMLTLCPKNRISTKEALNHPWF
.| |.... || .|||  |||.| .||.|.||. | |    .  .|| .  .. | .    .   .|.  .|| . |. ||| |.||.||.|
LFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNH-QQYPMYPAHQSWQQIVPK--LDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase DDB0229424.AA Pkinase 4-287 31 3.5e-80 277.47 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-293/293
Sequence Identity: 31% (97 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALKIISVMNIENGLPV------EVKYLMKLRDCKNIVHLIEYFYSNDDKLVMVFEYLEY-----DLWKFIS-P
..|.. |||||.|.|||..|  . ..||.|||.. ... . ..      |.... .| ...||| |...|.. .|.. ||.||.|      ||. .||  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTW

KNKYM--TLSCTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDL----KIADFGFTT---YIGNPHLAHQVISLFYRPPELLMGSRNYGPEVDIW
... .  .    ||.. |.|.||. .||..|.| |.||.|.||. . ..    ||.|||.     |  |. . . . ...|..||...|.. |||.||.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SVGCIIVEMLTGFYMFAGS----NDSLQLELIFKTFGTPTEKNWPGISKLSGYSPYLGSKSKKYPSKSLKDISKFKSFSNSTLDIILRMLTLCPKNRIST
|.|||. |||.|   | |.    |   |...|... |.|.. .||  .  | ..     . .       .  ..|.  | . .|.| ..|...|| |.. 
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------F-HWTFHNWSEECKDFIKWCLCKDPKKRPTA

KEALNHPWF
...|.||||
EQILQHPWF
Kinase DDB0229424.AA CDK7 4-287 34 1.3e-78 208.85 In-house 1-288 (288) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-288/288
Sequence Identity: 34% (103 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALKIIS----VMNIENGLPV----EVKYLMKLRDCKNIVHLIEYFYSNDDKLVMVFEYLEYDLWKFISPKNKY
...|..|| | .. ||||    .   || | |         . |.      |.|.|  ..   |.. ||  |   .  . .||.... ||   |  |   
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQ-HDNVIGLIDIFMHKSN-IQLVFDFMDWDLEVVIKDKSII

MTLSCTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDLKIADFGFTTYIGNPH--LAHQVISLFYRPPELLMGSRNYGPEVDIWSVGCIIVEMLT
.| .  | .  ..| ||  .|   | | |.|| |||.|.  .|||||||    .| |.  . |||.  .|| |||| | | ||. ||.||||||. | . 
LTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELML

GFYMFAGSNDSLQLELIFKTFGTPTEKNWPGISKLSGYSPYLGSKSKKYPS---KSLKDISKFKSFSNSTLDIILRMLTLCPKNRISTKEALNHPWF
    . | .|  ||. ||.| |||||..||.....  |      | |..|      |..|  |   |.  || . .|.|. | .|..  ..|..| |
RVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDY-----IKFKDFPGYSRTPLRHI--FTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase DDB0229424.AA CRK7 4-287 32 6.5e-70 238.59 In-house 1-343 (343) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-343/343
Sequence Identity: 32% (113 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALKIISVMNI---ENGLPV----EVKYLMKLRDCKNIVHLIEYFYS-------NDDK--LVMVFEYLEYDLWK
...|. ||.| ||.||||  .  .  |||| .   |    . | |.    |.| |  | . .||| | |   .       ...|    |||||   ||  
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQL-NHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMG

FISPK-NKYMTLSCTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDLKIADFGFTTYIGN----PHLAHQVISLFYRPPELLMGSRNY-------
    |  ..  ..  | |  |||||.| .| ....| ||| ||.|.| .  .||||||           . .   || | ||||||| |  .|       
LLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILK

-------------------------------GPEVDIWSVGCIIVEMLTGFYMFAGSNDSLQLELIFKTFGTPTEKNWPGISKLSGYSPYLGSKSKK-YP
                               |||.|.||.||| .| .|.  .| |.|   |||.|.|  |.|.  ||| . || ..      | |. | 
ELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTM---KPKRQYN

SKSLKDIS-KFK--SFSNSTLDIILRMLTLCPKNRISTKEALNHPWF
...... . ..|   ..   ||    ||.| || |.. .|.|.|.||
RRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase DDB0229424.AA CAMK 9-287 18 6.8e-67 214.33 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-287
Range on HMM: 1-425/425
Sequence Identity: 18% (84 aa)

LIGSGSYGKVYKAIHNLSK------------CTVALKIISV------------------------------MNIENGLPVEVKYLMKLR------DCKNI
 .|.||.|||...|| ...              || |||.                                . .  .. |.. ..||.      | .||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VHLIEYFYS-----------NDDK--------LVMVF---EYLEY-----DLWKFI--SPKN------------KYMTLSCTKFFIHQLLEGLDELHSQK
..|.|.. .           . .|        ..||.   || .      ||  .|   ...            ...| . ......|...... .||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHLDIKPSNLLINPR-----------------FDLKIADFGFTTYIGNPH-------------------------LAHQVISLFYRP-PELLMG-----
|.|.|.|| |.|.. .                 ...||.|||| ...   .                         .  .. .. | . ||.| |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------SRNYGPEVDIWSVGCIIVEMLTGFYMFAGSNDSLQLE---------LIFK-------TFGTPTEKN---------WPGISKLSGYSPYLGSK
         . |||..|.||.|.|   ||.|.. | |..|. ..|          .|.       .|  |  ..         | .||.           
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDE----------

SKKYPSKSLKDISKFKSFSNSTLDIILRMLTLCPKNRISTKEALNHPWF
           . .   .| .  | | .||.  |..|.. ...|||||.
-----------F-HH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DDB0229424.AA PFTAIRE 4-287 36 1.2e-66 227.78 In-house 1-287 (287) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-287/287
Sequence Identity: 36% (108 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALKIISVMNIENGLPV----EVKYLMKLRDCKNIVHLIEYFYSNDDKLVMVFEYLEYDLWKFISPKNKYMTLS
.. .|  | ||| .|||.|  . .  |||| |. .. | | |     |.  |  |.   ||| |       .  | .||||.. || ....  .  |   
YEKLEKLGEGSYATVYKGISCINQQFVALKEIR-LQQEEGTPFTAIREASLLKNLKHA-NIVCLHDIIHT-KETLTFVFEYVHTDLCQYMDKHPGGMHPN

CTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDLKIADFGF--TTYIGNPHLAHQVISLFYRPPELLMGSRNYGPEVDIWSVGCIIVEMLTGFYM
  . |. ||| ||   | ....| |.|| ||||     || ||||      .      | |. | ||||  |.|| .|  ..|.| |||| |||..|  .
NVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPA

FAGSNDSL-QLELIFKTFGTPTEKNWPGISKLSGYSPYLGSKSKKYPSKSLKDISKFKSFS--NSTLDIILRMLTLCPKNRISTKEALNHPWF
| |  | . |||.|||. |||||  |||...| .| |.   . . | .|.|. .  . . .  .   |..  || . |..|.|..||. ||.|
FPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHW-FRGRFYKPKKLCHQ--WPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase DDB0229424.AA PITSLRE 69-287 39 5.6e-59 202.25 In-house 73-295 (295) Show / Hide 
Range on Protein: 69-287
Range on HMM: 73-295/295
Sequence Identity: 39% (90 aa)

SNDDKLVMVFEYLEYDLWKFISPKN---KYMTLSCTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDLKIADFGFTTYIGNP--HLAHQVISLFY
|| ||  ||.||.| ||   .   .   .  ... .| .. ||| | . .|. .||| | | ||||..    |||.|||     | |   .   |. | |
SNMDKIYMVMEYVEHDLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWY

RPPELLMGSRNYGPEVDIWSVGCIIVEMLTGFYMFAGSNDSLQLELIFKTFGTPTEKNWPGISKLSGYSPYLGSKSKKYPSKSLKDISKFK---SFSNST
| |||| |.. | . ||.||||||  |..|.  .| |...  |.. ||| .|||||| |||...| .         ..||   |.  ..|.     |   
RAPELLLGCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNN--FPHYPYNNLR--KRFPAENHISDTG

LDIILRMLTLCPKNRISTKEALNHPWF
.|   .|||. |||||.  .|| ||||
FDLLNQMLTYNPKNRITASDALKHPWF
Kinase DDB0229424.AA TyrKc 4-287 17 7.7e-11 -47.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-280/280
Sequence Identity: 17% (56 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALKIISVMNIENGLPVEVKYLMKL-RDCKNIVHLIEYFYSN------DDKLVMVFEYLEY-DLWKFISPKNKY
 . .. .|.| .|.|||.. .    .|| | .     .  .  | . ..||  . .||| |. .  .       .. | .|.|| .. || ...  . . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

MTLSCTKFFIHQLLEGLDELHSQKIMHLDIKPSNLLINPRFDLKIADFGFTTYIGNP----------H-----LAHQVISLFYRPPELLMGSRNYGPEVD
 ...    | .|  .| . |||... | |.   | |.. ..  ||.||| . .|..           .      .. .. .   .|| .. .. . .. |
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-FTTKSD

IWSVGCIIVEMLTGFYMFAGS-----NDSLQLELIFKTFGTPTEKNW--PGISKLSGYSPYLGSKSKKYPSKSLKDISKFKSFSNSTLDIILRMLTLCPK
.|| |  . |..|   .          .  ..    |. . .       | .|                          |   .    .|...     |.
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS--------------------------FVCCPDEMYQIMKQCWHEDPE

NRISTKEALNHPWF
.| . .|   |  |
DRPTFSEI--HECF
Kinase DDB0229424.AA Pkinase_Tyr 4-83 23 2.5e-07 25.42 Pfam 1-91 (270) Show / Hide 
Range on Protein: 4-83
Range on HMM: 1-91/270
Sequence Identity: 23% (21 aa)

FQIIELIGSGSYGKVYKAIHN----LSKCTVALKII--SVMNIE---NGLPVEVKYLMKLRDCKNIVHLIEYFYSNDDK--LVMVFEYLEY
 .... .|.|..|.|||.. .      |..|| |..  . |  .     .  |.| ...| ...||| |.   .. ..   . .|.|| ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH
Kinase DDB0229424.AA PITSLRE 4-33 43 0.005149 7.07 In-house 1-30 (295) Show / Hide 
Range on Protein: 4-33
Range on HMM: 1-30/295
Sequence Identity: 43% (13 aa)

FQIIELIGSGSYGKVYKAIHNLSKCTVALK
||..  |. | || ||.|   .    ||||
FQCLNRIHEGTYGVVYRAKDKRTDEIVALK
Kinase DDB0229424.AA CDK-DD1 1222-1272 46 0.000332 8.21 In-house 233-284 (379) Show / Hide 
Range on Protein: 1222-1272
Range on HMM: 233-284/379
Sequence Identity: 46% (24 aa)

FSPLLNSA-SQDINNNSRSSRHRSKLNIDTKGNNNNNNNNKNNNNNNNNNNN
.......   |  | |  | .. |... .   |||||||| |||||||||||
YNQYFHKQQQQQQNENNYSKQYPSRNRNNNNNNNNNNNNNNNNNNNNNNNNN