Gene DDB0229427 (Slime mold)

DDB0229427

Species: Slime mold
Alias: DdisK054, DDB0229427
External Links: DictyBase Link ,
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: PITSLRE

Sequence

Name Sequence Type Origin Length Description Download
DDB0229427.AA Protein None 366 None Fasta, JSON
DDB0229427.kin_dom Protein Kinase Domain None 287 None Fasta, JSON

Protein domain

Protein domains of DDB0229427.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229427.AA PITSLRE 7-293 58 1.5e-221 742.35 In-house 1-295 (295) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-295/295
Sequence Identity: 58% (173 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIG-QQDKDGIPLTSLREIQ-ILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNIN---
|..|..|.|||||.|....||.|..|||||..|.. |..|.|.|.||||||. ||....|||||...|.|.||..||||.|.||.|||..||..|..   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

KPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYSTAVDLWSIGSIFGEL
.|||..||||...||||.||..|..||.|||||.|||||...|.||..||||||..|.||...|||.||||||.|||||||.||||.||.||.|.||.|.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

LIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVP---TISDTAFDLLNQLLTYDPTKRITASDAIKHPFF
....||..|..|.|||..||...|.|.|.||||...||..|..||.||.||||||...|   .||||.||||||.|||.|..|||||||.|||.|
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase DDB0229427.AA CDK 7-293 43 1.4e-169 546.85 In-house 1-284 (284) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-284/284
Sequence Identity: 43% (139 aa)

FEKLDSIGEGTYGIVSKGRDKETG-----RIVALKKVKIGQQ----DKDGIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGD---------KIYLVFEY
.|||. |||||||.| |.|||.||     .||||||... ..    .|.|.| |..||| .|||. |||||.|..|..... |         |.|.||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LEHDVASLIDNINKPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGN-----LKLADFGLARKFGY------PIESITPCMVTLWYRSPE
..|| ....|          |||...||||...|.||.||.|||||..|.|. |||.     ||.|||||||.||       |.   |. .||||||.||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLLGCQKYS--TAVDLWSIGSIFGELLI---GRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVPTISDTAFDLLNQ
||||...||  |..|.||.| ||.|..    ..||  |..| ||. .||...| |.|..|||...||..                          ||||.
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------DLLNK

LLTYDPTKRITASDAIKHPFF
.|.|||.|||.|..| .||.|
MLCYDPKKRISAEQALQHPYF
Kinase DDB0229427.AA CDC2 7-293 45 1.9e-145 450.3 In-house 1-301 (301) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-301/301
Sequence Identity: 45% (140 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDKD-GIPLTSLREIQILKEIK-HPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLID---NIN
..|.  |||||||.| |..|..|..||||||... |.| . |.| |..||| .|||.| |||||.| .|..     |.|.|||||..|   . |     |
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

KPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPC--MVTLWYRSPELLLGCQKYSTAVDLWSIGSIFG
|.. .. .| .. |.|..|...|.. |.||||| .|.|  ..||.|.||||||| ||.||  .|.    ||||||.||.||||..|||.||.|||| || 
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EL---LIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVPT---------ISDTAFDLLNQLLTYDPTKRITASDA
|.      .||  |  | ||. .||  || ||||.||| ..|| .|  |  |  . ..|....|          . ....|||.|.| ||| |||.| .|
EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYK--NTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEA

IKHPFF
..||.|
LQHPYF
Kinase DDB0229427.AA CDK7 7-293 40 1.1e-141 380.31 In-house 1-288 (288) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-288/288
Sequence Identity: 40% (117 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVK-IGQQD--KDGIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNINKP
.||.. ||||... |.|..|..||.||| ||.| .| ..  ||||  | .||| ||.|..|.|.. |. .      . |.|||.... |    |      
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFM--HKSNIQLVFDFMDWDLEVVIKDKSII

FKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYSTAVDLWSIGSIFGELLI
.. ..|| . ...|. .||.| .|| |||||  |||   || ||.||||||| .| | .  |.  || |||.|||| |   | |.||.||.| || ||. 
LTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELML

GRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVPTISDTAFDLLNQLLTYDPTKRITASDAIKHPFF
  | . | ...||. |||. || |.|. ||. ......  . . |      ||..    || . ||.  ..| .| ||.|.... |.|.|
RVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase DDB0229427.AA CMGC 7-293 26 5.70000000001e-141 466.48 In-house 1-513 (513) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-513/513
Sequence Identity: 26% (136 aa)

FEKLDSIGEGTYGIVSKGRD--------------KETGRIVALKKVK-----IGQQ---DKDGIPLTSLREIQILKEIK-----------------HPNI
.|... |||||||.| |.||              .||..|||.||.|     ....    |||.| ..||||.|||...                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VSLLEVVIGSTGD---------------KIYLVFEYLEHDVASLIDNINK--------PFKLSE------------IKCFL------LQLLRAVE--YLH
|.|....  .  |               ..||||||..|| . .|.| ..        |..  .            ||.|.       |.||...  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SHW--IIHRDLKCSNLLYGNN--------------------GNLKLADFGLARKFGYP---------------------IESITPCMVTLWYRSPELLLG
|||  ||||||| .|.|  .|                    |.||..||||||... .                      . .|.  ||.|||.||.|||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

C---------QKYSTAVDLWSIGSIFGELLIG--------RPLITGNNE-----------VDQIMRIFNLLGEPN---------------EQIWPGFSSL
.         ..|.|..| ||.| ||.|.. |        .||  |..|           .||. .||..|| |.               |..||....|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PNFKR---------------------LNN---IPHQPYNNLRELVPT-----------------------------------ISDTAFDLLNQLLTYDPT
|...                      ...    | .|......|.|                                    ... |.|||...|.|||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRITASDAIKHPFF
|||||..| .||.|
KRITAEQALQHPYF
Kinase DDB0229427.AA CDK10 7-293 51 1.9e-132 446.35 In-house 1-285 (285) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-285/285
Sequence Identity: 51% (148 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDKDGIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNINKPFKL
||||  .|||||||| . ||  .  |||||||.. ...|||.|. .||||..|....|.||| | |||.|   | |.|| .| | |.|||.||. .||  
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRM-DKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQPFTE

SEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYSTAVDLWSIGSIFGELLIGRP
...||  ||.||.. |||....|||||| ||||   .| .|.|||||||..| |.  .|| ||||||| |||||||..  ||.|.| .| | ||||...|
TQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKP

LITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVPTISDTAFDLLNQLLTYDPTKRITASDAIKHPFF
|. || |. ||  | .||| |.|.|||||| ||  ..   . .||||||..  . .|..   ||| |. |.| || || ....  .|
LMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNF-TLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase DDB0229427.AA CDK5 7-293 45 1.5e-127 405.25 In-house 1-287 (287) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-287/287
Sequence Identity: 45% (131 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDKDGIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNINKPFKL
.||.. |||||||.| |.|.|||. |||||.|.. . |  |.| | .||| .|||.||.||| |  |.   .  |. ||||..  |    .|..|    .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSED-EGVPSTAIREICLLKELKHKNIVRLHDVIH--SEKKLTLVFEFCDQDLKKYMDSCNGEMDM

SEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYSTAVDLWSIGSIFGELL-IGR
  || |..|||. ... |.| . |||||  |||   ||.|||||||||| || |.   .   |||||| |  |.| ..||| .|.||.| || |.   ||
HIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGR

PLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFK-RLNNIPHQPYNN-LRELVPTISDTAFDLLNQLLTYDPTKRITASDAIKHPFF
||  ||.. || .||| ..| |.|  ||. . ||..|   .. |  | .  . ..||  . .  |||...| ..| .||.| .|..||.|
PLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase DDB0229427.AA CRK7 7-293 35 9.3e-110 370.94 In-house 1-343 (343) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-343/343
Sequence Identity: 35% (124 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQD---KDGIPLTSLREIQILKEIKHPNIVSLLEVVIG------STGDK--IYLVFEYLEHDVAS
.|... ||||||| | | ..|.|| .||||||.  . .   |.| | |. ||| ||.. .|.||| | |.|.       .  .|  .|.||||  || . 
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRM-DNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMG

LIDNI-NKPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPI--ESITPCMVTLWYRSPELLLGCQKY-------
| ..   . | ....|||. |||  ..|.|   ..|||.||||.|. |.|..|.|||||||..         |   .||||| |||||| ..|       
LLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILK

-------------------------------STAVDLWSIGSIFGELLIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNN
                                ...| || | |.|||. ..|.  |||| .|.  |. . | || . ||    || .. .   | . || 
ELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMK--PKRQYNR

-LRELVP------TISDTAFDLLNQLLTYDPTKRITASDAIKHPFF
 ||| .        ..  ..||| ..|..||.||.||...  |..|
RLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase DDB0229427.AA S_TKc 7-293 32 2.4e-103 350.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-231/231
Sequence Identity: 32% (97 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDKDGIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEH---DVASLIDNINKP
.|.|. ||.|..| | |.|.|.||||||.|..|           . .|||||||. .||||| |..|      |..|.|.||...   |. ..|.. ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----FKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYST-AVDLWSIGSI
     |   ...... |...|.||.|||.||||||| .|.|  .  ..|..||||||..       | . .|.||..||.|    .|.. ..| ||.| |
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

FGELLIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVPTISDTAFDLLNQLLTYDPTKRITASDAIK-------H
. |.| |.|.        |....|...|                                     |. | |.....|..||.||.|| .| .       |
LYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

PFF
|.|
PWF
Kinase DDB0229427.AA CDK4 7-293 40 1.1e-100 340.86 In-house 1-290 (290) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-290/290
Sequence Identity: 40% (119 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDK-DGIPLTSLREIQILK---EIKHPNIVSLLEVVIGSTGDK----IYLVFEYLEHDVASLID
....  |||| ||.| . || .||..||||.|.|  ..   |.|.  .||| ...      |||||.|..|   .  |     | .|||  . | . ..|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

NINKP-FKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYSTAVDLWSIGSI
.. .|      ||    ||||.|..|||| |||||||  |.|   .| .||||||||| ...     ||  ||||||.|| ||  . | | ||.||.| |
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMA-LTPVVVTLWYRAPEVLL-QSYYNTPVDMWSVGCI

FGELLIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVPTISDTAFDLLNQLLTYDPTKRITASDAIKHPFF
| |.   |||  |..|.||  .|| . | | |. ||  .|||    .   | .   ......| ..  . |||.. |.|.. ||..|  . .||.|
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLP----WDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase DDB0229427.AA Pkinase 7-293 35 3.3e-95 327.38 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-293/293
Sequence Identity: 35% (108 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDKDGIPLTSLR--EIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNI----
....  ||.|..| | |...| ||.|||.|..|    .|.. . | .|  ||||.|...||||| |....    .|.||.|.||.|...  ..|      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFDYIS

---NKPF--KLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNL----KLADFGLARKF-GYPIESITPCMVTLWYRSPELLLGCQKYSTAVD
   ...|     |.|....|.||..||.||..||||||| .|.|. |||..    |..|||||..|   . .  |   .|.||..||...|.|.|...||
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

LWSIGSIFGELLIGRPLITGN----NEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVPTISDTAFDLLNQLLTYDPTKRITASD
 ||.| |. |.| |||.  |     | .||. .|.. .| |..  ||  .| ..|. ..  .      .... . .|... |... .|..||.||.|| .
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQ

AIKHPFF
. .||.|
ILQHPWF
Kinase DDB0229427.AA PFTAIRE 7-293 39 9e-89 301.22 In-house 1-287 (287) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-287/287
Sequence Identity: 39% (115 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDKDGIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNINKPFKL
.|||.  |||.|  | ||. . ....|||| ...  |.  | | |  ||   ||. || ||| |  ..   |     .||||.. | .  .|  .   . 
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRL--QQEEGTPFTAIREASLLKNLKHANIVCLHDIIH--TKETLTFVFEYVHTDLCQYMDKHPGGMHP

SEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYSTAVDLWSIGSIFGELLIGRP
  .. || ||||   | |   . |||||  |||  . | ||||||||||    |        |||||| |  |||   ||| .|.| .| || |.. |.|
NNVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQP

LITGN-NEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNI--PHQPYNNLRELVPTIS--DTAFDLLNQLLTYDPTKRITASDAIKHPFF
.  |  .  ||  .|| .|| |.|. ||| ..|||.|   .    ..|  .|.. .| |.    |.||....| . | .|. | .|..||.|
AFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKP-KKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase DDB0229427.AA Pkinase_Tyr 7-155 32 5.4e-23 78.5 Pfam 1-159 (270) Show / Hide 
Range on Protein: 7-155
Range on HMM: 1-159/270
Sequence Identity: 32% (54 aa)

FEKLDSIGEGTYGIVSKGRDK----ETGRIVALKKVKIGQQDKDGIPLTS------LREIQILKEI-KHPNIVSLLEVVIGSTGDK--IYLVFEYLEH-D
 ...  .||| .| | ||. |    .|.  || |..|      .|           .||..|.|.. .|||||.|. |.. . |.   ||.|.|| .| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT-DQGEPNQIYIVMEYMPHGD

VASLIDNI---NKPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLAR
  .   .    ..|...... .. .|  .. |||.|. .||||| . | | ..|.  | .||||||
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase DDB0229427.AA TyrKc 7-293 23 5.5e-15 19.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-293
Range on HMM: 1-280/280
Sequence Identity: 23% (75 aa)

FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDKDGIPLTSLREIQILKEI--KHPNIVSLLEVVIGSTG-----DKIYLVFEYLEH-DVASLI-
 .... .||| .|.| ||. |   . || |..| .           .||..|....  .||||| |. |.. . .     . ...|.|| .| |  . . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DNINKPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPI-------ESITP-----CM--VTLWYRSPELLLGCQ
.. .| .....   | .|  .  |||||. .||||| . | |.|.|.  | .||||.| ..|         . ...     .   . .   .|| .  . 
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSR-DIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG-

KYSTAVDLWSIGSI------FGELLIGRPLI--TGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVPTISDTAFDLLNQLLT
|..|. | || |        .|.     .      | || .  .  . .  | .   |  |                       .. .|  ...  |   
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS----------------------FVCCPDEMYQIMKQCWH

YDPTKRITASDAIKHPFF
.|| .| | |.   | .|
EDPEDRPTFSEI--HECF